-
1
-
-
0025284206
-
Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge
-
Wenzel SE, Larsen GL, Johnston K, Voelkel NF, Westcott JY (1990) Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge. Am Rev Respir Dis 142(1):112-119.
-
(1990)
Am Rev Respir Dis
, vol.142
, Issue.1
, pp. 112-119
-
-
Wenzel, S.E.1
Larsen, G.L.2
Johnston, K.3
Voelkel, N.F.4
Westcott, J.Y.5
-
2
-
-
0025892285
-
Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects
-
Christie PE, et al. (1991) Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects. Am Rev Respir Dis 143(5 Pt 1): 1025-1029.
-
(1991)
Am Rev Respir Dis
, vol.143
, Issue.5
, pp. 1025-1029
-
-
Christie, P.E.1
-
3
-
-
84860322842
-
Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes
-
Laidlaw TM, et al. (2012) Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes. Blood 119(16): 3790-3798.
-
(2012)
Blood
, vol.119
, Issue.16
, pp. 3790-3798
-
-
Laidlaw, T.M.1
-
4
-
-
0026613070
-
Recovery of leukotriene E4 from the urine of patients with airway obstruction
-
Drazen JM, et al. (1992) Recovery of leukotriene E4 from the urine of patients with airway obstruction. Am Rev Respir Dis 146(1):104-108.
-
(1992)
Am Rev Respir Dis
, vol.146
, Issue.1
, pp. 104-108
-
-
Drazen, J.M.1
-
5
-
-
0033600291
-
Characterization of the human cysteinyl leukotriene CysLT1 receptor
-
Lynch KR, et al. (1999) Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature 399(6738):789-793.
-
(1999)
Nature
, vol.399
, Issue.6738
, pp. 789-793
-
-
Lynch, K.R.1
-
6
-
-
0035152877
-
Expression of the cysteinyl leukotriene 1 receptor in normal human lung and peripheral blood leukocytes
-
Figueroa DJ, et al. (2001) Expression of the cysteinyl leukotriene 1 receptor in normal human lung and peripheral blood leukocytes. Am J Respir Crit Care Med 163(1): 226-233.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, Issue.1
, pp. 226-233
-
-
Figueroa, D.J.1
-
7
-
-
0037824477
-
Effects of cysteinyl leukotrienes in small human bronchus and antagonist activity of montelukast and its metabolites
-
Mechiche H, et al. (2003) Effects of cysteinyl leukotrienes in small human bronchus and antagonist activity of montelukast and its metabolites. Clin Exp Allergy 33(7): 887-894.
-
(2003)
Clin Exp Allergy
, vol.33
, Issue.7
, pp. 887-894
-
-
Mechiche, H.1
-
8
-
-
18744421762
-
Montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction
-
Leff JA, et al. (1998) Montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction. N Engl J Med 339(3): 147-152.
-
(1998)
N Engl J Med
, vol.339
, Issue.3
, pp. 147-152
-
-
Leff, J.A.1
-
9
-
-
33646594755
-
Cysteinyl leukotriene 2 receptor and protease-activated receptor 1 activate strongly correlated early genes in human endothelial cells
-
Uzonyi B, et al. (2006) Cysteinyl leukotriene 2 receptor and protease-activated receptor 1 activate strongly correlated early genes in human endothelial cells. Proc Natl Acad Sci USA 103(16):6326-6331.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.16
, pp. 6326-6331
-
-
Uzonyi, B.1
-
10
-
-
40449090322
-
Endothelial cysteinyl leukotriene 2 receptor expression mediates myocardial ischemia-reperfusion injury
-
JiangW, et al. (2008) Endothelial cysteinyl leukotriene 2 receptor expression mediates myocardial ischemia-reperfusion injury. Am J Pathol 172(3):592-602.
-
(2008)
Am J Pathol
, vol.172
, Issue.3
, pp. 592-602
-
-
Jiang, W.1
-
11
-
-
84878994214
-
Localization and up-regulation of cysteinyl leukotriene-2 receptor in human allergic nasal mucosa
-
Shirasaki H, et al. (2013) Localization and up-regulation of cysteinyl leukotriene-2 receptor in human allergic nasal mucosa. Allergol Int 62(2):223-228.
-
(2013)
Allergol Int
, vol.62
, Issue.2
, pp. 223-228
-
-
Shirasaki, H.1
-
12
-
-
84888223159
-
Cysteinyl leukotrienes regulate endothelial cell inflammatory and proliferative signals through CysLT2 and CysLT1 receptors
-
Duah E, et al. (2013) Cysteinyl leukotrienes regulate endothelial cell inflammatory and proliferative signals through CysLT2 and CysLT1 receptors. Sci Rep 3:3274.
-
(2013)
Sci Rep
, vol.3
, pp. 3274
-
-
Duah, E.1
-
13
-
-
84924247048
-
Leukotriene C4 induces bronchoconstriction and airway vascular hyperpermeability via the cysteinyl leukotriene receptor 2 in S-hexyl glutathione-treated Guinea pigs
-
Yonetomi Y, et al. (2015) Leukotriene C4 induces bronchoconstriction and airway vascular hyperpermeability via the cysteinyl leukotriene receptor 2 in S-hexyl glutathione-treated guinea pigs. Eur J Pharmacol 754:98-104.
-
(2015)
Eur J Pharmacol
, vol.754
, pp. 98-104
-
-
Yonetomi, Y.1
-
14
-
-
84944170814
-
Expression of CysLT2 receptors in asthma lung, and their possible role in bronchoconstriction
-
Sekioka T, et al. (2015) Expression of CysLT2 receptors in asthma lung, and their possible role in bronchoconstriction. Allergol Int 64(4):351-358.
-
(2015)
Allergol Int
, vol.64
, Issue.4
, pp. 351-358
-
-
Sekioka, T.1
-
15
-
-
0022378008
-
In vivo metabolism of leukotriene C4 in man: Urinary excretion of leukotriene E4
-
Orning L, Kaijser L, Hammarström S (1985) In vivo metabolism of leukotriene C4 in man: Urinary excretion of leukotriene E4. Biochem Biophys Res Commun 130(1): 214-220.
-
(1985)
Biochem Biophys Res Commun
, vol.130
, Issue.1
, pp. 214-220
-
-
Orning, L.1
Kaijser, L.2
Hammarström, S.3
-
16
-
-
0023161876
-
The excretion of leukotriene E4 into urine following inhalation of leukotriene D4 by human individuals
-
Verhagen J, et al. (1987) The excretion of leukotriene E4 into urine following inhalation of leukotriene D4 by human individuals. Biochem Biophys Res Commun 148(2):864-868.
-
(1987)
Biochem Biophys Res Commun
, vol.148
, Issue.2
, pp. 864-868
-
-
Verhagen, J.1
-
17
-
-
0023947133
-
Release of leukotrienes in patients with bronchial asthma
-
Lam S, Chan H, LeRiche JC, Chan-Yeung M, Salari H (1988) Release of leukotrienes in patients with bronchial asthma. J Allergy Clin Immunol 81(4):711-717.
-
(1988)
J Allergy Clin Immunol
, vol.81
, Issue.4
, pp. 711-717
-
-
Lam, S.1
Chan, H.2
LeRiche, J.C.3
Chan-Yeung, M.4
Salari, H.5
-
18
-
-
0025572770
-
Leukotriene E4 elimination and metabolism in normal human subjects
-
Sala A, Voelkel N, Maclouf J, Murphy RC (1990) Leukotriene E4 elimination and metabolism in normal human subjects. J Biol Chem 265(35):21771-21778.
-
(1990)
J Biol Chem
, vol.265
, Issue.35
, pp. 21771-21778
-
-
Sala, A.1
Voelkel, N.2
Maclouf, J.3
Murphy, R.C.4
-
19
-
-
0034730638
-
Characterization of the human cysteinyl leukotriene 2 receptor
-
Heise CE, et al. (2000) Characterization of the human cysteinyl leukotriene 2 receptor. J Biol Chem 275(39):30531-30536.
-
(2000)
J Biol Chem
, vol.275
, Issue.39
, pp. 30531-30536
-
-
Heise, C.E.1
-
20
-
-
0023152470
-
Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects
-
Davidson AB, et al. (1987) Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects. Am Rev Respir Dis 135(2):333-337.
-
(1987)
Am Rev Respir Dis
, vol.135
, Issue.2
, pp. 333-337
-
-
Davidson, A.B.1
-
21
-
-
0024242242
-
The relative responsiveness to inhaled leukotriene E4, methacholine and histamine in normal and asthmatic subjects
-
O'Hickey SP, Arm JP, Rees PJ, Spur BW, Lee TH (1988) The relative responsiveness to inhaled leukotriene E4, methacholine and histamine in normal and asthmatic subjects. Eur Respir J 1(10):913-917.
-
(1988)
Eur Respir J
, vol.1
, Issue.10
, pp. 913-917
-
-
O'Hickey, S.P.1
Arm, J.P.2
Rees, P.J.3
Spur, B.W.4
Lee, T.H.5
-
22
-
-
0023745152
-
The effects of inhaled leukotriene E4 on the airway responsiveness to histamine in subjects with asthma and normal subjects
-
Arm JP, Spur BW, Lee TH (1988) The effects of inhaled leukotriene E4 on the airway responsiveness to histamine in subjects with asthma and normal subjects. J Allergy Clin Immunol 82(4):654-660.
-
(1988)
J Allergy Clin Immunol
, vol.82
, Issue.4
, pp. 654-660
-
-
Arm, J.P.1
Spur, B.W.2
Lee, T.H.3
-
23
-
-
0020693480
-
Local effects of synthetic leukotrienes (LTC4, LTD4, LTE4, and LTB4) in human skin
-
Soter NA, Lewis RA, Corey EJ, Austen KF (1983) Local effects of synthetic leukotrienes (LTC4, LTD4, LTE4, and LTB4) in human skin. J Invest Dermatol 80(2):115-119.
-
(1983)
J Invest Dermatol
, vol.80
, Issue.2
, pp. 115-119
-
-
Soter, N.A.1
Lewis, R.A.2
Corey, E.J.3
Austen, K.F.4
-
24
-
-
55949121449
-
Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors
-
Maekawa A, Kanaoka Y, Xing W, Austen KF (2008) Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors. Proc Natl Acad Sci USA 105(43):16695-16700.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.43
, pp. 16695-16700
-
-
Maekawa, A.1
Kanaoka, Y.2
Xing, W.3
Austen, K.F.4
-
25
-
-
84876578638
-
Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand
-
Kanaoka Y, Maekawa A, Austen KF (2013) Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand. J Biol Chem 288(16):10967-10972.
-
(2013)
J Biol Chem
, vol.288
, Issue.16
, pp. 10967-10972
-
-
Kanaoka, Y.1
Maekawa, A.2
Austen, K.F.3
-
26
-
-
60549110301
-
Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells
-
Barrett NA, Maekawa A, Rahman OM, Austen KF, Kanaoka Y (2009) Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells. J Immunol 182(2):1119-1128.
-
(2009)
J Immunol
, vol.182
, Issue.2
, pp. 1119-1128
-
-
Barrett, N.A.1
Maekawa, A.2
Rahman, O.M.3
Austen, K.F.4
Kanaoka, Y.5
-
27
-
-
33646852272
-
Regulation of cytosolic phospholipase A2 activation and cyclooxygenase 2 expression in macrophages by the beta-glucan receptor
-
Suram S, et al. (2006) Regulation of cytosolic phospholipase A2 activation and cyclooxygenase 2 expression in macrophages by the beta-glucan receptor. J Biol Chem 281(9):5506-5514.
-
(2006)
J Biol Chem
, vol.281
, Issue.9
, pp. 5506-5514
-
-
Suram, S.1
-
28
-
-
79952729913
-
Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes
-
Barrett NA, et al. (2011) Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes. J Exp Med 208(3):593-604.
-
(2011)
J Exp Med
, vol.208
, Issue.3
, pp. 593-604
-
-
Barrett, N.A.1
-
29
-
-
84882778526
-
Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production
-
Doherty TA, et al. (2013) Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production. J Allergy Clin Immunol 132(1):205-213.
-
(2013)
J Allergy Clin Immunol
, vol.132
, Issue.1
, pp. 205-213
-
-
Doherty, T.A.1
-
30
-
-
84965019138
-
Transcriptional profiling of tissue resident mast cells reveals a unique identity within the immune system
-
Dwyer DF, Barrett NA, Austen KF (2016) Transcriptional profiling of tissue resident mast cells reveals a unique identity within the immune system. Nat Immunol, 10.1038/ni.3445.
-
(2016)
Nat Immunol
-
-
Dwyer, D.F.1
Barrett, N.A.2
Austen, K.F.3
-
31
-
-
2442649129
-
Citric acid cycle intermediates as ligands for orphan G-proteincoupled receptors
-
He W, et al. (2004) Citric acid cycle intermediates as ligands for orphan G-proteincoupled receptors. Nature 429(6988):188-193.
-
(2004)
Nature
, vol.429
, Issue.6988
, pp. 188-193
-
-
He, W.1
-
32
-
-
79955048969
-
Conjunctival goblet cell secretion stimulated by leukotrienes is reduced by resolvins D1 and E1 to promote resolution of inflammation
-
Dartt DA, et al. (2011) Conjunctival goblet cell secretion stimulated by leukotrienes is reduced by resolvins D1 and E1 to promote resolution of inflammation. J Immunol 186(7):4455-4466.
-
(2011)
J Immunol
, vol.186
, Issue.7
, pp. 4455-4466
-
-
Dartt, D.A.1
-
33
-
-
84937691064
-
Leukotriene E4 induces MUC5AC release from human airway epithelial NCI-H292 cells
-
Shirasaki H, Kanaizumi E, Seki N, Himi T (2015) Leukotriene E4 induces MUC5AC release from human airway epithelial NCI-H292 cells. Allergol Int 64(2):169-174.
-
(2015)
Allergol Int
, vol.64
, Issue.2
, pp. 169-174
-
-
Shirasaki, H.1
Kanaizumi, E.2
Seki, N.3
Himi, T.4
-
34
-
-
0025034495
-
Asthmatic airways have a disproportionate hyperresponsiveness to LTE4, as compared with normal airways, but not to LTC4, LTD4, methacholine, and histamine
-
Arm JP, et al. (1990) Asthmatic airways have a disproportionate hyperresponsiveness to LTE4, as compared with normal airways, but not to LTC4, LTD4, methacholine, and histamine. Am Rev Respir Dis 142(5):1112-1118.
-
(1990)
Am Rev Respir Dis
, vol.142
, Issue.5
, pp. 1112-1118
-
-
Arm, J.P.1
-
35
-
-
84923361939
-
The polymeric mucin Muc5ac is required for allergic airway hyperreactivity
-
Evans CM, et al. (2015) The polymeric mucin Muc5ac is required for allergic airway hyperreactivity. Nat Commun 6:6281.
-
(2015)
Nat Commun
, vol.6
, pp. 6281
-
-
Evans, C.M.1
-
36
-
-
0037812532
-
Characterization of airway plugging in fatal asthma
-
Kuyper LM, et al. (2003) Characterization of airway plugging in fatal asthma. Am J Med 115(1):6-11.
-
(2003)
Am J Med
, vol.115
, Issue.1
, pp. 6-11
-
-
Kuyper, L.M.1
-
37
-
-
0035933888
-
Attenuated zymosan-induced peritoneal vascular permeability and IgE-dependent passive cutaneous anaphylaxis in mice lacking leukotriene C4 synthase
-
Kanaoka Y, Maekawa A, Penrose JF, Austen KF, Lam BK (2001) Attenuated zymosan-induced peritoneal vascular permeability and IgE-dependent passive cutaneous anaphylaxis in mice lacking leukotriene C4 synthase. J Biol Chem 276(25):22608-22613.
-
(2001)
J Biol Chem
, vol.276
, Issue.25
, pp. 22608-22613
-
-
Kanaoka, Y.1
Maekawa, A.2
Penrose, J.F.3
Austen, K.F.4
Lam, B.K.5
-
38
-
-
8544261165
-
Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in mice
-
Beller TC, Maekawa A, Friend DS, Austen KF, Kanaoka Y (2004) Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in mice. J Biol Chem 279(44):46129-46134.
-
(2004)
J Biol Chem
, vol.279
, Issue.44
, pp. 46129-46134
-
-
Beller, T.C.1
Maekawa, A.2
Friend, D.S.3
Austen, K.F.4
Kanaoka, Y.5
-
39
-
-
0037036414
-
Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses
-
Maekawa A, Austen KF, Kanaoka Y (2002) Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses. J Biol Chem 277(23):20820-20824.
-
(2002)
J Biol Chem
, vol.277
, Issue.23
, pp. 20820-20824
-
-
Maekawa, A.1
Austen, K.F.2
Kanaoka, Y.3
-
40
-
-
41049104888
-
Mast cell-specific Cre/loxP-mediated recombination in vivo
-
Scholten J, et al. (2008) Mast cell-specific Cre/loxP-mediated recombination in vivo. Transgenic Res 17(2):307-315.
-
(2008)
Transgenic Res
, vol.17
, Issue.2
, pp. 307-315
-
-
Scholten, J.1
-
41
-
-
79959362680
-
Mast cells are key promoters of contact allergy that mediate the adjuvant effects of haptens
-
Dudeck A, et al. (2011) Mast cells are key promoters of contact allergy that mediate the adjuvant effects of haptens. Immunity 34(6):973-984.
-
(2011)
Immunity
, vol.34
, Issue.6
, pp. 973-984
-
-
Dudeck, A.1
-
43
-
-
0022922136
-
Measurement by radioimmunoassay of prostaglandins as their methyl oximes
-
Kelly RW, Deam S, Cameron MJ, Seamark RF (1986) Measurement by radioimmunoassay of prostaglandins as their methyl oximes. Prostaglandins Leukot Med 24(1): 1-14.
-
(1986)
Prostaglandins Leukot Med
, vol.24
, Issue.1
, pp. 1-14
-
-
Kelly, R.W.1
Deam, S.2
Cameron, M.J.3
Seamark, R.F.4
-
45
-
-
84897493899
-
Mouse mast cell proteases 4 and 5 mediate epidermal injury through disruption of tight junctions
-
Bankova LG, et al. (2014) Mouse mast cell proteases 4 and 5 mediate epidermal injury through disruption of tight junctions. J Immunol 192(6):2812-2820.
-
(2014)
J Immunol
, vol.192
, Issue.6
, pp. 2812-2820
-
-
Bankova, L.G.1
|