Bipolar disorder course, impaired glucose metabolism and antioxidant enzymes activities: A preliminary report

Journal of Psychiatric Research

Volumn 80, Issue , 2016, Pages 38-44

  Mansur, Rodrigo B ^a,b   Rizzo, Lucas B ^a,c   Santos, Camila M ^a   Asevedo, Elson ^a   Cunha, Graccielle R ^a   Noto, Mariane N ^a,d   Pedrini, Mariana ^a   Zeni Graiff, Maiara ^a   Gouvea, Eduardo S ^e   Cordeiro, Quirino ^e   Reininghaus, Eva Z ^f   McIntyre, Roger S ^b   Brietzke, Elisa ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d Vila Maria Outpatient Clinic   (Brazil)

^e IRMANDADE DA SANTA CASA DE MISERICÓRDIA DE SÃO PAULO   (Brazil)

^f MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Bipolar disorder; Diabetes mellitus; Impaired glucose metabolism; Oxidative stress

Indexed keywords

ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; GLUCOSE; GLUTATHIONE PEROXIDASE; INSULIN; LITHIUM; METFORMIN; NEUROLEPTIC AGENT; PIOGLITAZONE; SUPEROXIDE DISMUTASE;

ADULT; ARTICLE; BIPOLAR DISORDER; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; DYSLIPIDEMIA; ENZYME ACTIVITY; FEMALE; GLUCOSE METABOLISM; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INSULIN TREATMENT; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; ONSET AGE; OXIDATIVE STRESS; PRESCRIPTION; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; BLOOD; BODY MASS; COMORBIDITY; COMPLICATION; METABOLISM; MIDDLE AGED; PSYCHOLOGICAL RATING SCALE; STATISTICS;

ADULT; BIPOLAR DISORDER; BODY MASS INDEX; COMORBIDITY; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCOSE; GLUTATHIONE PEROXIDASE; HUMANS; MALE; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; STATISTICS AS TOPIC; SUPEROXIDE DISMUTASE;

EID: 84973102988     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2016.05.014     Document Type: Article

References (53)

1. Abdalla D.S., Monteiro H.P., Oliveira J.A., Bechara E.J. Activities of superoxide dismutase and glutathione peroxidase in schizophrenic and manic-depressive patients. Clin. Chem. 1986, 32:805-807.
2. Andreazza A.C., Cassini C., Rosa A.R., Leite M.C., de Almeida L.M., Nardin P., et al. Serum S100B and antioxidant enzymes in bipolar patients. J. Psychiatr. Res. 2007, 41:523-529.
3. Andreazza A.C., Kapczinski F., Kauer-Sant'Anna M., Walz J.C., Bond D.J., Gonçalves C.A., et al. 3-Nitrotyrosine and glutathione antioxidant system in patients in the early and late stages of bipolar disorder. J. Psychiatry Neurosci. 2009, 34:263-271.
4. Andreazza A.C., Kauer-Sant'anna M., Frey B.N., Bond D.J., Kapczinski F., Young L.T., et al. Oxidative stress markers in bipolar disorder: a meta-analysis. J. Affect. Disord. 2008, 111:135-144.
5. Association AD Standards of medical care in diabetes-2014. Diabetes Care 2014, 37(Suppl. 1):S14-S80.
6. Baldessarini R.J., Salvatore P., Khalsa H.M., Imaz-Etxeberria H., Gonzalez-Pinto A., Tohen M. Episode cycles with increasing recurrences in first-episode bipolar-I disorder patients. J. Affect. Disord. 2012, 136:149-154.
7. Bandeira Sde M., Guedes Gda S., da Fonseca L.J., Pires A.S., Gelain D.P., Moreira J.C., et al. Characterization of blood oxidative stress in type 2 diabetes mellitus patients: increase in lipid peroxidation and SOD activity. Oxid. Med. Cell Longev. 2012, 2012:819310.
8. Banerjee M., Vats P. Reactive metabolites and antioxidant gene polymorphisms in Type 2 diabetes mellitus. Redox Biol. 2013, 2C:170-177.
9. Baynes J.W. Role of oxidative stress in development of complications in diabetes. Diabetes 1991, 40:405-412.
10. Berk M., Berk L., Dodd S., Cotton S., Macneil C., Daglas R., et al. Stage managing bipolar disorder. Bipolar Disord. 2014, 16:471-477.
11. Berk M., Kapczinski F., Andreazza A.C., Dean O.M., Giorlando F., Maes M., et al. Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors. Neurosci. Biobehav Rev. 2011, 35:804-817.
12. Brietzke E., Kapczinski F., Grassi-Oliveira R., Grande I., Vieta E., McIntyre R.S. Insulin dysfunction and allostatic load in bipolar disorder. Expert Rev. Neurother. 2011, 11:1017-1028.
13. Brown N.C., Andreazza A.C., Young L.T. An updated meta-analysis of oxidative stress markers in bipolar disorder. Psychiatry Res. 2014, 218:61-68.
14. Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes 2005, 54:1615-1625.
15. Calkin C.V., Ruzickova M., Uher R., Hajek T., Slaney C.M., Garnham J.S., et al. Insulin resistance and outcome in bipolar disorder. Br. J. Psychiatry 2015, 206:52-57.
16. Ceriello A., Motz E. Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited. Arterioscler. Thromb. Vasc. Biol. 2004, 24:816-823.
17. Chen X., Scholl T.O., Leskiw M.J., Donaldson M.R., Stein T.P. Association of glutathione peroxidase activity with insulin resistance and dietary fat intake during normal pregnancy. J. Clin. Endocrinol. Metab. 2003, 88:5963-5968.
18. Crump C., Sundquist K., Winkleby M.A., Sundquist J. Comorbidities and mortality in bipolar disorder: a Swedish National Cohort study. JAMA Psychiatry 2013, 70(9):931-939.
19. Frey B.N., Andreazza A.C., Houenou J., Jamain S., Goldstein B.I., Frye M.A., et al. Biomarkers in bipolar disorder: a positional paper from the international society for bipolar disorders biomarkers task force. Aust. N. Z. J. Psychiatry 2013, 47:321-332.
20. Fries G.R., Vasconcelos-Moreno M.P., Gubert C., dos Santos B.T., Sartori J., Eisele B., et al. Hypothalamic-pituitary-adrenal axis dysfunction and illness progression in bipolar disorder. Int. J. Neuropsychopharmacol. 2014, 18.
21. Fullerton J.M., Tiwari Y., Agahi G., Heath A., Berk M., Mitchell P.B., et al. Assessing oxidative pathway genes as risk factors for bipolar disorder. Bipolar Disord. 2010, 12:550-556.
22. Gama C.S., Kunz M., Magalhaes P.V., Kapczinski F. Staging and neuroprogression in bipolar disorder: a systematic review of the literature. Rev. Bras. Psiquiatr. 2013, 35:70-74.
23. Gergerlioglu H.S., Savas H.A., Bulbul F., Selek S., Uz E., Yumru M. Changes in nitric oxide level and superoxide dismutase activity during antimanic treatment. Prog. Neuropsychopharmacol. Biol. Psychiatry 2007, 31:697-702.
24. Gomes F.A., Almeida K.M., Magalhaes P.V., Caetano S.C., Kauer-Sant'Anna M., Lafer B., et al. Cardiovascular risk factors in outpatients with bipolar disorder: a report from the Brazilian Research Network in Bipolar Disorder. Rev. Bras. Psiquiatr. 2013, 35:126-130.
25. Gomez Garcia A., Rivera Rodriguez M., Gomez Alonso C., Rodriguez Ochoa D.Y., Alvarez Aguilar C. Myeloperoxidase is associated with insulin resistance and inflammation in overweight subjects with first-degree relatives with type 2 diabetes mellitus. Diabetes Metab. J. 2015, 39:59-65.
26. Guo Z., Xia Z., Jiang J., McNeill J.H. Downregulation of NADPH oxidase, antioxidant enzymes, and inflammatory markers in the heart of streptozotocin-induced diabetic rats by N-acetyl-L-cysteine. Am. J. Physiol. Heart Circ. Physiol. 2007, 292:H1728-H1736.
27. Hansen L.L., Ikeda Y., Olsen G.S., Busch A.K., Mosthaf L. Insulin signaling is inhibited by micromolar concentrations of H(2)O(2). Evidence for a role of H(2)O(2) in tumor necrosis factor alpha-mediated insulin resistance. J. Biol. Chem. 1999, 274:25078-25084.
28. Kapczinski F., Magalhaes P.V., Balanza-Martinez V., Dias V.V., Frangou S., Gama C.S., et al. Staging systems in bipolar disorder: an international society for bipolar disorders task force report. Acta Psychiatr. Scand. 2014, 130:354-363.
29. Kapczinski F., Vieta E., Andreazza A.C., Frey B.N., Gomes F.A., Tramontina J., et al. Allostatic load in bipolar disorder: implications for pathophysiology and treatment. Neurosci. Biobehav Rev. 2008, 32:675-692.
30. Kemp D.E., Gao K., Chan P.K., Ganocy S.J., Findling R.L., Calabrese J.R. Medical comorbidity in bipolar disorder: relationship between illnesses of the endocrine/metabolic system and treatment outcome. Bipolar Disord. 2010, 12:404-413.
31. Kornhauser C., Garcia-Ramirez J.R., Wrobel K., Perez-Luque E.L., Garay-Sevilla M.E., Wrobel K. Serum selenium and glutathione peroxidase concentrations in type 2 diabetes mellitus patients. Prim. Care Diabetes 2008, 2:81-85.
32. Kuloglu M., Ustundag B., Atmaca M., Canatan H., Tezcan A.E., Cinkilinc N. Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar disorder. Cell Biochem. Funct. 2002, 20:171-175.
33. Kunz M., Gama C.S., Andreazza A.C., Salvador M., Cereser K.M., Gomes F.A., et al. Elevated serum superoxide dismutase and thiobarbituric acid reactive substances in different phases of bipolar disorder and in schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 2008, 32:1677-1681.
34. Laybutt D.R., Kaneto H., Hasenkamp W., Grey S., Jonas J.C., Sgroi D.C., et al. Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia. Diabetes 2002, 51:413-423.
35. Machado-Vieira R., Andreazza A.C., Viale C.I., Zanatto V., Cereser V., da Silva Vargas R., et al. Oxidative stress parameters in unmedicated and treated bipolar subjects during initial manic episode: a possible role for lithium antioxidant effects. Neurosci. Lett. 2007, 421:33-36.
36. Magalhaes P.V., Dodd S., Nierenberg A.A., Berk M. Cumulative morbidity and prognostic staging of illness in the systematic treatment enhancement program for bipolar disorder (STEP-BD). Aust. N. Z. J. Psychiatry 2012, 46:1058-1067.
37. Mahadev K., Wu X., Zilbering A., Zhu L., Lawrence J.T., Goldstein B.J. Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes. J. Biol. Chem. 2001, 276:48662-48669.
38. Mansur R.B., Brietzke E., McIntyre R.S. Is there a "metabolic-mood syndrome"? A review of the relationship between obesity and mood disorders. Neurosci. Biobehav Rev. 2015, 52:89-104.
39. Mansur R.B., Rizzo L.B., Santos C.M., Asevedo A., Cunha G.R., Noto M.N., et al. Adipokines, metabolic dysfunction and illness course in bipolar disorder. J. Psychiatr. Res. 2016, 74:63-69.
40. Ozcan M.E., Gulec M., Ozerol E., Polat R., Akyol O. Antioxidant enzyme activities and oxidative stress in affective disorders. Int. Clin. Psychopharmacol. 2004, 19:89-95.
41. Panizzutti B., Gubert C., Schuh A.L., Ferrari P., Bristot G., Fries G.R., et al. Increased serum levels of eotaxin/CCL11 in late-stage patients with bipolar disorder: an accelerated aging biomarker?. J. Affect. Disord. 2015, 182:64-69.
42. 2 as an enable signal for triggering autophosphorylation of insulin receptor in neurons. J. Mol. Signal. 2013, 8:11.
43. Perugi G., Quaranta G., Belletti S., Casalini F., Mosti N., Toni C., et al. General medical conditions in 347 bipolar disorder patients: clinical correlates of metabolic and autoimmune-allergic diseases. J. Affect. Disord. 2015, 170:95-103.
44. Peters A.T., West A.E., Eisner L., Baek J., Deckersbach T. The burden of repeated mood episodes in bipolar I disorder: results from the National epidemiological Survey on alcohol and related conditions. J. Nerv. Ment. Dis. 2016, 204:87-94.
45. Ranjekar P.K., Hinge A., Hegde M.V., Ghate M., Kale A., Sitasawad S., et al. Decreased antioxidant enzymes and membrane essential polyunsaturated fatty acids in schizophrenic and bipolar mood disorder patients. Psychiatry Res. 2003, 121:109-122.
46. Reininghaus E.Z., Lackner N., Fellendorf F.T., Bengesser S., Birner A., Reininghaus B., et al. Weight cycling in bipolar disorder. J. Affect. Disord. 2015, 171:33-38.
47. Ruzickova M., Slaney C., Garnham J., Alda M. Clinical features of bipolar disorder with and without comorbid diabetes mellitus. Can. J. Psychiatry 2003, 48:458-461.
48. Savas H.A., Gergerlioglu H.S., Armutcu F., Herken H., Yilmaz H.R., Kocoglu E., et al. Elevated serum nitric oxide and superoxide dismutase in euthymic bipolar patients: impact of past episodes. World J. Biol. Psychiatry 2006, 7:51-55.
49. Selek S., Savas H.A., Gergerlioglu H.S., Bulbul F., Uz E., Yumru M. The course of nitric oxide and superoxide dismutase during treatment of bipolar depressive episode. J. Affect. Disord. 2008, 107:89-94.
50. Sociedade Brasileira de Cardiologia, Xavier H.T., Izar M.C., Faria Neto J.R., Assad M.H., Rocha V.Z., et al. V Brazilian guidelines on dyslipidemias and prevention of atherosclerosis. Arq. Bras. Cardiol. 2013, 101:1-20.
51. Storozhevykh T.P., Senilova Y.E., Persiyantseva N.A., Pinelis V.G., Pomytkin I.A. Mitochondrial respiratory chain is involved in insulin-stimulated hydrogen peroxide production and plays an integral role in insulin receptor autophosphorylation in neurons. BMC Neurosci. 2007, 8:84.
52. Tinahones F.J., Murri-Pierri M., Garrido-Sanchez L., Garcia-Almeida J.M., Garcia-Serrano S., Garcia-Arnes J., et al. Oxidative stress in severely obese persons is greater in those with insulin resistance. Obes. (Silver Spring) 2009, 17:240-246.
53. Turan V., Sezer E.D., Zeybek B., Sendag F. Infertility and the presence of insulin resistance are associated with increased oxidative stress in young, non-obese Turkish women with polycystic ovary syndrome. J. Pediatr. Adolesc. Gynecol. 2015, 28:119-123.