Palmitoylated claudin7 captured in glycolipid-enriched membrane microdomains promotes metastasis via associated transmembrane and cytosolic molecules

Oncotarget

Volumn 7, Issue 21, 2016, Pages 30659-30677

  Thuma, Florian ^a   Heiler, Sarah ^a   Schnölzer, Martina ^b   Zöller, Margot ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Claudin7 palmitoylation; Complex dependent bioactivity; Glycolipid enriched membrane microdomains; Metastasis

Indexed keywords

ALPHA6BETA4 INTEGRIN; CISPLATIN; CLAUDIN 7; CYTOKERATIN 2; EZRIN; GLYCOGEN SYNTHASE KINASE 3BETA; GLYCOLIPID; MATRIX METALLOPROTEINASE 14; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; UROKINASE RECEPTOR; CLAUDIN; CLDN7 PROTEIN, RAT; MEMBRANE PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER RESISTANCE; CELL MOTILITY; CELL ORGANELLE; CELL TRANSPORT; CELL VACUOLE; CELLULAR DISTRIBUTION; CLD7 GENE; CONTROLLED STUDY; CYTOSOL; EPITHELIAL MESENCHYMAL TRANSITION; EXOSOME; GENE EXPRESSION; GENE SILENCING; GLYCOLIPID ENRICHED MEMBRANE MICRODOMAIN; METASTASIS; METASTASIS POTENTIAL; NONHUMAN; PALMITOYLATION; PANCREAS ADENOCARCINOMA; PANCREATIC CANCER CELL LINE; PROTEIN LOCALIZATION; RAT; TUMOR INVASION; ADENOCARCINOMA; ANIMAL; CELL MOTION; GENETICS; LIPOYLATION; MEMBRANE MICRODOMAIN; METABOLISM; PANCREAS TUMOR; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ADENOCARCINOMA; ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; CLAUDINS; CYTOSOL; EXOSOMES; GENE KNOCKDOWN TECHNIQUES; GLYCOLIPIDS; LIPOYLATION; MEMBRANE MICRODOMAINS; MEMBRANE PROTEINS; NEOPLASM METASTASIS; PANCREATIC NEOPLASMS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84971578053     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.8928     Document Type: Article

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