Overcoming barriers in the study of tight junction functions: From occludin to claudin

Genes to Cells

Volumn 3, Issue 9, 1998, Pages 569-573

  Tsukita, Shoichiro ^a   Furuse, Mikio ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MEMBRANE PROTEIN; OCCLUDIN;

ENDOTHELIUM CELL; EPITHELIUM CELL; IMMUNOELECTRON MICROSCOPY; MEMBRANE MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVIEW; TIGHT JUNCTION;

ANIMALS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; TIGHT JUNCTIONS;

EID: 0031741390     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.1998.00212.x     Document Type: Review

References (40)

1. Anderson, J.M. & Van Itallie, C.M. (1995) Tight junctions and the molecular basis for regulation of paracellular permeability. Am. J. Physiol. 269, G467-G475.
2. Ando-Akatsuka, Y, Saitou, M., Hirase, T., et al. (1996) Inter-species diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. J. Cell Biol. 133, 43-47.
3. Balda, M.S., Whitney, J.A., Flores, C., González, S., Cereijido, M. & Matter, K. (1996) Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein. J. Cell Biol. 134, 1031-1049.
4. Chen, Y.-H., Merzdorf, C., Paul, D.L. & Goodenough, D.A. (1997) COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos. J. Cell Biol. 138, 891-899.
5. Citi, S., Sabanay, H., Jakes, R., Geiger, B. & Kendrick-Jones, J. (1988) Cingulin, a new peripheral component of tight junctions. Nature (Lond.) 333, 272-276.
6. Farquhar, M.G. & Palade, G.E. (1963) Junctional complexes in various epithelia. J. Cell Biol. 17, 375-412.
7. Fujimoto, K. (1995) Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling of intercellular junctional complexes. J. Cell Sci. 108, 3443-3449.
8. Furuse, M., Fujimoto, K., Sato, N., Hirase, T., Tsukita, Sa. & Tsukita, Sh. (1996) Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures. J. Cell Sci. 109, 429-435.
9. Furuse, M., Fujita, K., Hiiragi, T., Fujimoto, K. & Tsukita, Sh. (1998) Claudin-1 and -2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J. Cell Biol. 141, 1539-1550.
10. Furuse, M., Hirase, T., Itoh, M., et al. (1993) Occludin: a novel integral membrane protein localizing at tight junctions. J. Cell Biol. 123, 1777-1788.
11. Furuse, M., Itoh, M., Hirase, T., et al. (1994) Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J. Cell Biol. 127, 1617-1626.
12. Gumbiner, B.M. (1987) Structure, biochemistry, and assembly of epithelial tight junctions. Am. J. Physiol. 253, C749-C758.
13. Gumbiner, B.M. (1993) Breaking through the tight junction barrier. J. Cell Biol. 123, 1631-1633.
14. Gumbiner, B., Lowenkopf, T. & Apatira, D. (1991) Identification of a 160kDa polypeptide that binds to the tight junction protein ZO-1. Proc. Natl. Acad. Sci. USA 88, 3460-3464.
15. Haskins, J., Gu, L., Wittchen, E.S., Hibbard, J. & Stevenson, B.R. (1998) ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J. Cell Biol. 141, 199-208.
16. Hirase, T., Staddon, J.M., Saitou, M., et al. (1997) Occludin as a possible determinant of tight junction permeability in endothelial cells. J. Cell Sci. 110, 1603-1613.
17. Itoh, M., Nagafuchi, A., Yonemura, S., Kitani-Yasuda, T., Tsukita, Sa. & Tsukita, Sh. (1993) The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy. J. Cell Biol. 121, 491-502.
18. Itoh, M., Yonemura, S., Nagafuchi, A., Tsukita, Sa. & Tsukita, Sh. (1991) A 220-kD undercoat-constitutive protein: Its specific localization at cadherin-based cell-cell adhesion sites. J. Cell Biol. 115, 1449-1462.
19. Jiang, J.X. & Goodenough, D.A. (1996) Heteromeric connexons in lens gap junction channels. Proc. Natl. Acad. Sci. USA 93, 1287-1291.
20. Kachar, B. & Reese, T.S. (1982) Evidence for the lipidic nature of tight junction strands. Nature 296, 464-466.
21. Keon, B.H., Schäfer, S., Kuhn, C., Grund, C. & Franke, W.W. (1996) Symplekin, a novel type of tight junction plaque protein. J. Cell Biol. 134, 1003-1018.
22. Kumar, N.M. & Gilula, N.B. (1996) The gap junction communication channel. Cell 84, 381-388.
23. McCarthy, K.M., Skare, I.B., Stankewich, M.C., et al. (1996) Occludin is a functional component of the tight junction. J. Cell Sci. 109, 2287-2298.
24. Moroi, S., Saitou, M., Fujimoto, K., et al. (1998) Occludin is concentrated at tight junctions of mouse/rat but not human/ guinea pig Sertoli cells in testes. Am. J. Physiol., 274, C1708-C1717.
25. Pinto da Silva, P. & Kachar, B. (1982) On tight junction structure. Cell 28, 441-450.
26. Rodriguez-Boulan, E. & Nelson, W.J. (1989) Morphogenesis of the polarized epithelial cell phenotype. Science 245, 718-725.
27. Saitou, M., Ando-Akatsuka, Y., Itoh, M., et al. (1997) Mammalian occludin in epithelial cells: its expression and subcellular distribution. Eur. J. Cell Biol. 73, 222-231.
28. Saitou, M., Fujimoto, K., Doi, Y, et al. (1998) Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J. Cell Biol. 141, 397-408.
29. Sakakibara, A., Furuse, M., Saitou, M., Ando-Akatsuka, Y & Tsukita, Sh. (1997) Possible involvement of phosphorylation of occludin in tight junction formation. J. Cell Biol. 137, 1393-1401.
30. Schneeberger, E.E. & Lynch, R.D. (1992) Structure, function, and regulation of cellular tight junctions. Am. J. Physiol. 262, L647-L661.
31. Staehelin, L.A. (1973) Further observations on the fine structure of freeze-cleaved tight junctions. J. Cell Sci. 13, 763-786.
32. Staehelin, L.A. (1974) Structure and function of intercellular junctions. Int. Rev. Cytol 39, 191-283.
33. Stevenson, B.R., Anderson, J.M. & Bullivant, S. (1988) The epithelial tight junction: Structure, function and preliminary biochemical characterization. Mol. Cell. Biochem. 83, 129-145.
34. Stevenson, B.R. & Goodenough, D. (1984) Zonula occludentes in junctional complex-enriched fractions from mouse liver: preliminary morphological and biochemical characterization. J. Cell Biol. 98, 1209-1221.
35. Stevenson, B.R., Siliciano, J.D., .Mooseker, M.S. & Goodenough, D.A. (1986) Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J. Cell Biol. 103, 755-766.
36. Tsukita, Sh. & Tsukita, Sa. (1989) Isolation of cell-to-cell adherens junctions from rat liver. J. Cell Biol. 108, 31-41.
37. Van Itallie, C.M. & Anderson, J.M. (1997) Occludin confers adhesiveness when expressed in fibroblasts. J. Cell Sci. 110, 1113-1121.
38. Verkleiji, A.J. (1984) Lipidic intramembranous particles. Biochim. Biophys. Acta A 779, 43-63.
39. Wong, V. & Gumbiner, B.M. (1997) A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier. J. Cell Biol. 136, 399-409.
40. Zhong, Y., Saitoh, T., Minase, T., Sawada, N., Enomoto, K. & Mori, M. (1993) Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin, and ZO-2. J. Cell Biol. 120, 477-483.