메뉴 건너뛰기




Volumn 131, Issue 2, 2015, Pages 79-84

Modulation of the Innate Immune Response through the Vagus Nerve

Author keywords

Cholinergic anti inflammatory pathway; Cytokines; Heart rate variability; Inflammation; Innate immune system; Lipopolysaccharide; Vagus nerve

Indexed keywords

ANIMAL; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; PHYSIOLOGY; VAGUS NERVE;

EID: 84971551927     PISSN: 16608151     EISSN: 22353186     Source Type: Journal    
DOI: 10.1159/000435843     Document Type: Review
Times cited : (27)

References (60)
  • 1
    • 0036305603 scopus 로고    scopus 로고
    • The systemic inflammatory response to cardiac surgery: Implications for the anesthesiologist
    • Laffey JG, Boylan JF, Cheng DC: The systemic inflammatory response to cardiac surgery: implications for the anesthesiologist. Anesthesiology 2002; 97: 215-252.
    • (2002) Anesthesiology , vol.97 , pp. 215-252
    • Laffey, J.G.1    Boylan, J.F.2    Cheng, D.C.3
  • 3
    • 0033638849 scopus 로고    scopus 로고
    • The sympathetic nerve-an integrative interface between two supersystems: The brain and the immune system
    • Elenkov IJ, Wilder RL, Chrousos GP, Vizi ES: The sympathetic nerve-an integrative interface between two supersystems: The brain and the immune system. Pharmacol Rev 2000; 52: 595-638.
    • (2000) Pharmacol Rev , vol.52 , pp. 595-638
    • Elenkov, I.J.1    Wilder, R.L.2    Chrousos, G.P.3    Vizi, E.S.4
  • 4
    • 0029087509 scopus 로고
    • Subdiaphragmatic vagotomy suppresses endotoxininduced activation of hypothalamic corticotropin-releasing hormone neurons and ACTH secretion
    • Gaykema RP, Dijkstra I, Tilders FJ: Subdiaphragmatic vagotomy suppresses endotoxininduced activation of hypothalamic corticotropin-releasing hormone neurons and ACTH secretion. Endocrinology 1995; 136: 4717-4720.
    • (1995) Endocrinology , vol.136 , pp. 4717-4720
    • Gaykema, R.P.1    Dijkstra, I.2    Tilders, F.J.3
  • 5
    • 0032525793 scopus 로고    scopus 로고
    • Thermogenic and corticosterone responses to intravenous cytokines (IL-1beta and TNF-alpha) are attenuated by subdiaphragmatic vagotomy
    • Fleshner M, Goehler LE, Schwartz BA, McGorry M, Martin D, Maier SF, Watkins LR: Thermogenic and corticosterone responses to intravenous cytokines (IL-1beta and TNF-alpha) are attenuated by subdiaphragmatic vagotomy. J Neuroimmunol 1998; 86: 134-141.
    • (1998) J Neuroimmunol , vol.86 , pp. 134-141
    • Fleshner, M.1    Goehler, L.E.2    Schwartz, B.A.3    McGorry, M.4    Martin, D.5    Maier, S.F.6    Watkins, L.R.7
  • 8
    • 0037180778 scopus 로고    scopus 로고
    • The inflammatory reflex
    • Tracey KJ: The inflammatory reflex. Nature 2002; 420: 853-859.
    • (2002) Nature , vol.420 , pp. 853-859
    • Tracey, K.J.1
  • 9
    • 0037305675 scopus 로고    scopus 로고
    • Musings on the wanderer: What's new in our understanding of vago-vagal reflexes III. Activity-dependent plasticity in vago-vagal reflexes controlling the stomach
    • Travagli RA, Hermann GE, Browning KN, Rogers RC: Musings on the wanderer: what's new in our understanding of vago-vagal reflexes III. Activity-dependent plasticity in vago-vagal reflexes controlling the stomach. Am J Physiol Gastrointest Liver Physiol 2003; 284:G180-G187.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284 , pp. G180-G187
    • Travagli, R.A.1    Hermann, G.E.2    Browning, K.N.3    Rogers, R.C.4
  • 10
    • 0026038742 scopus 로고
    • The effects of interleukin-1 beta on the activity of adrenal, splenic and renal sympathetic nerves in the rat
    • Niijima A, Hori T, Aou S, Oomura Y: The effects of interleukin-1 beta on the activity of adrenal, splenic and renal sympathetic nerves in the rat. J Auton Nerv Syst 1991; 36: 183-192.
    • (1991) J Auton Nerv Syst , vol.36 , pp. 183-192
    • Niijima, A.1    Hori, T.2    Aou, S.3    Oomura, Y.4
  • 11
    • 0036605657 scopus 로고    scopus 로고
    • Overview of the innervation of the lung
    • Belvisi MG: Overview of the innervation of the lung. Curr Opin Pharmacol 2002; 2: 211-215.
    • (2002) Curr Opin Pharmacol , vol.2 , pp. 211-215
    • Belvisi, M.G.1
  • 12
    • 0037370875 scopus 로고    scopus 로고
    • Musings on the wanderer: What's new in our understanding of vago-vagal reflex IV. Current concepts of vagal efferent projections to the gut
    • Chang HY, Mashimo H, Goyal RK: Musings on the wanderer: what's new in our understanding of vago-vagal reflex IV. Current concepts of vagal efferent projections to the gut. Am J Physiol Gastrointest Liver Physiol 2003; 284:G357-G366.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284 , pp. G357-G366
    • Chang, H.Y.1    Mashimo, H.2    Goyal, R.K.3
  • 13
    • 26044437911 scopus 로고    scopus 로고
    • The cholinergic antiinflammatory pathway
    • Pavlov VA, Tracey KJ: The cholinergic antiinflammatory pathway. Brain Behav Immun 2005; 19: 493-499.
    • (2005) Brain Behav Immun , vol.19 , pp. 493-499
    • Pavlov, V.A.1    Tracey, K.J.2
  • 14
    • 0027439308 scopus 로고
    • Acetylcholinesterase staining and choline acetyltransferase activity in the young adult rat spleen: Lack of evidence for cholinergic innervation
    • Bellinger DL, Lorton D, Hamill RW, Felten SY, Felten DL: Acetylcholinesterase staining and choline acetyltransferase activity in the young adult rat spleen: lack of evidence for cholinergic innervation. Brain Behav Immun 1993; 7: 191-204.
    • (1993) Brain Behav Immun , vol.7 , pp. 191-204
    • Bellinger, D.L.1    Lorton, D.2    Hamill, R.W.3    Felten, S.Y.4    Felten, D.L.5
  • 17
    • 79955021499 scopus 로고    scopus 로고
    • 7-cholinergic receptor mediates vagal induction of splenic norepinephrine
    • Vida G, Pena G, Deitch EA, Ulloa L: 7-cholinergic receptor mediates vagal induction of splenic norepinephrine. J Immunol 2011; 186: 4340-4346.
    • (2011) J Immunol , vol.186 , pp. 4340-4346
    • Vida, G.1    Pena, G.2    Deitch, E.A.3    Ulloa, L.4
  • 22
    • 54049157816 scopus 로고    scopus 로고
    • The protective effect of the cholinergic anti-inflammatory pathway against septic shock in rats
    • Song XM, Li JG, Wang YL, Hu ZF, Zhou Q, Du ZH, Jia BH: The protective effect of the cholinergic anti-inflammatory pathway against septic shock in rats. Shock 2008; 30: 468-472.
    • (2008) Shock , vol.30 , pp. 468-472
    • Song, X.M.1    Li, J.G.2    Wang, Y.L.3    Hu, Z.F.4    Zhou, Q.5    Du, Z.H.6    Jia, B.H.7
  • 24
    • 84871998505 scopus 로고    scopus 로고
    • Parasympathetic stimulation via the vagus nerve prevents systemic organ dysfunction by abrogating gut injury and lymph toxicity in trauma and hemorrhagic shock
    • Levy G, Fishman JE, Xu D, Chandler BT, Feketova E, Dong W, Qin Y, Alli V, Ulloa L, Deitch EA: Parasympathetic stimulation via the vagus nerve prevents systemic organ dysfunction by abrogating gut injury and lymph toxicity in trauma and hemorrhagic shock. Shock 2013; 39: 39-44.
    • (2013) Shock , vol.39 , pp. 39-44
    • Levy, G.1    Fishman, J.E.2    Xu, D.3    Chandler, B.T.4    Feketova, E.5    Dong, W.6    Qin, Y.7    Alli, V.8    Ulloa, L.9    Deitch, E.A.10
  • 31
    • 0033544431 scopus 로고    scopus 로고
    • Long-term treatment with vagus nerve stimulation in patients with refractory epilepsy. The Vagus Nerve Stimulation Study Group E01-E05
    • Morris GL 3rd, Mueller WM: Long-term treatment with vagus nerve stimulation in patients with refractory epilepsy. The Vagus Nerve Stimulation Study Group E01-E05. Neurology 1999; 53: 1731-1735.
    • (1999) Neurology , vol.53 , pp. 1731-1735
    • Morris, G.L.1    Mueller, W.M.2
  • 32
    • 79953787411 scopus 로고    scopus 로고
    • Effectiveness and safety of vagus nerve stimulation for severe treatment-resistant major depression in clinical practice after FDA approval: Outcomes at 1 year
    • Cristancho P, Cristancho MA, Baltuch GH, Thase ME, O'Reardon JP: Effectiveness and safety of vagus nerve stimulation for severe treatment-resistant major depression in clinical practice after FDA approval: outcomes at 1 year. J Clin Psychiatry 2011; 72: 1376-1382.
    • (2011) J Clin Psychiatry , vol.72 , pp. 1376-1382
    • Cristancho, P.1    Cristancho, M.A.2    Baltuch, G.H.3    Thase, M.E.4    O'Reardon, J.P.5
  • 35
    • 24944445120 scopus 로고    scopus 로고
    • The effects of vagus nerve stimulation on pro-and anti-inflammatory cytokines in humans: A preliminary report
    • Corcoran C, Connor TJ, O'Keane V, Garland MR: The effects of vagus nerve stimulation on pro-and anti-inflammatory cytokines in humans: A preliminary report. Neuroimmunomodulation 2005; 12: 307-309.
    • (2005) Neuroimmunomodulation , vol.12 , pp. 307-309
    • Corcoran, C.1    Connor, T.J.2    O'Keane, V.3    Garland, M.R.4
  • 36
    • 69949182019 scopus 로고    scopus 로고
    • Effects of vagus nerve stimulation on pro-and anti-inflammatory cytokine induction in patients with refractory epilepsy
    • De Herdt V, Bogaert S, Bracke KR, Raedt R, De Vos M, Vonck K, Boon P: Effects of vagus nerve stimulation on pro-and anti-inflammatory cytokine induction in patients with refractory epilepsy. J Neuroimmunol 2009; 214: 104-108.
    • (2009) J Neuroimmunol , vol.214 , pp. 104-108
    • De Herdt, V.1    Bogaert, S.2    Bracke, K.R.3    Raedt, R.4    De Vos, M.5    Vonck, K.6    Boon, P.7
  • 39
    • 68349160714 scopus 로고    scopus 로고
    • GTS-21 inhibits pro-inflammatory cytokine release independent of the Toll-like receptor stimulated via a transcriptional mechanism involving JAK2 activation
    • Kox M, van Velzen JF, Pompe JC, Hoedemaekers CW, van der Hoeven JG, Pickkers P: GTS-21 inhibits pro-inflammatory cytokine release independent of the Toll-like receptor stimulated via a transcriptional mechanism involving JAK2 activation. Biochem Pharmacol 2009; 78: 863-872.
    • (2009) Biochem Pharmacol , vol.78 , pp. 863-872
    • Kox, M.1    Van Velzen, J.F.2    Pompe, J.C.3    Hoedemaekers, C.W.4    Van Der Hoeven, J.G.5    Pickkers, P.6
  • 41
    • 84924769578 scopus 로고    scopus 로고
    • Evidence of different mediators of central inflammation in dysfunctional and inflammatory pain-interleukin-8 in fibromyalgia and interleukin-1 in rheumatoid arthritis
    • Kosek E, Altawil R, Kadetoff D, Finn A, Westman M, Le Maitre E, Andersson M, Jensen-Urstad M, Lampa J: Evidence of different mediators of central inflammation in dysfunctional and inflammatory pain-interleukin-8 in fibromyalgia and interleukin-1 in rheumatoid arthritis. J Neuroimmunol 2015; 280: 49-55.
    • (2015) J Neuroimmunol , vol.280 , pp. 49-55
    • Kosek, E.1    Altawil, R.2    Kadetoff, D.3    Finn, A.4    Westman, M.5    Le Maitre, E.6    Andersson, M.7    Jensen-Urstad, M.8    Lampa, J.9
  • 43
    • 84954488107 scopus 로고    scopus 로고
    • Heart rate variability predicts levels of inflammatory markers: Evidence for the vagal anti-inflammatory pathway
    • Cooper TM, McKinley PS, Seeman TE, Choo TH, Lee S, Sloan RP: Heart rate variability predicts levels of inflammatory markers: evidence for the vagal anti-inflammatory pathway. Brain Behav Immun 2014;pii:S0889-S1591.
    • (2014) Brain Behav Immun , pp. S0889-S1591
    • Cooper, T.M.1    McKinley, P.S.2    Seeman, T.E.3    Choo, T.H.4    Lee, S.5    Sloan, R.P.6
  • 44
    • 34250638610 scopus 로고    scopus 로고
    • RR interval variability is inversely related to inflammatory markers: The CARDIA study
    • Sloan RP, McCreath H, Tracey KJ, Sidney S, Liu K, Seeman T: RR interval variability is inversely related to inflammatory markers: The CARDIA study. Mol Med 2007; 13: 178-184.
    • (2007) Mol Med , vol.13 , pp. 178-184
    • Sloan, R.P.1    McCreath, H.2    Tracey, K.J.3    Sidney, S.4    Liu, K.5    Seeman, T.6
  • 47
    • 79954624827 scopus 로고    scopus 로고
    • Heart rate variability and biomarkers of systemic inflammation in patients with stable coronary heart disease: Findings from the Heart and Soul study
    • von Kanel R, Carney RM, Zhao S, Whooley MA: Heart rate variability and biomarkers of systemic inflammation in patients with stable coronary heart disease: findings from the Heart and Soul study. Clin Res Cardiol 2011; 100: 241-247.
    • (2011) Clin Res Cardiol , vol.100 , pp. 241-247
    • Von Kanel, R.1    Carney, R.M.2    Zhao, S.3    Whooley, M.A.4
  • 48
    • 80051552949 scopus 로고    scopus 로고
    • Interplay between the acute inflammatory response and heart rate variability in healthy human volunteers
    • Kox M, Ramakers BP, Pompe JC, van der Hoeven JG, Hoedemaekers CW, Pickkers P: Interplay between the acute inflammatory response and heart rate variability in healthy human volunteers. Shock 2011; 36: 115-120.
    • (2011) Shock , vol.36 , pp. 115-120
    • Kox, M.1    Ramakers, B.P.2    Pompe, J.C.3    Van Der Hoeven, J.G.4    Hoedemaekers, C.W.5    Pickkers, P.6
  • 49
    • 0030802265 scopus 로고    scopus 로고
    • Endotoxin impedes vasoconstriction in the spleen: Role of endogenous interleukin-1 and sympathetic innervation
    • Rogausch H, del Rey A, Kabiersch A, Reschke W, Ortel J, Besedovsky H: Endotoxin impedes vasoconstriction in the spleen: role of endogenous interleukin-1 and sympathetic innervation. Am J Physiol 1997; 272:R2048-R2054.
    • (1997) Am J Physiol , vol.272 , pp. R2048-R2054
    • Rogausch, H.1    Del Rey, A.2    Kabiersch, A.3    Reschke, W.4    Ortel, J.5    Besedovsky, H.6
  • 50
    • 0030445888 scopus 로고    scopus 로고
    • Assessment of depth of midazolam sedation using objective parameters
    • Haberthur C, Lehmann F, Ritz R: Assessment of depth of midazolam sedation using objective parameters. Intensive Care Med 1996; 22: 1385-1390.
    • (1996) Intensive Care Med , vol.22 , pp. 1385-1390
    • Haberthur, C.1    Lehmann, F.2    Ritz, R.3
  • 51
    • 0027372717 scopus 로고
    • Components of heart rate variability-what they really mean and what we really measure
    • Malik M, Camm AJ: Components of heart rate variability-what they really mean and what we really measure. Am J Cardiol 1993; 72: 821-822.
    • (1993) Am J Cardiol , vol.72 , pp. 821-822
    • Malik, M.1    Camm, A.J.2
  • 54
    • 26844436564 scopus 로고    scopus 로고
    • Nutritional stimulation of cholecystokinin receptors inhibits inflammation via the vagus nerve
    • Luyer MD, Greve JW, Hadfoune M, Jacobs JA, Dejong CH, Buurman WA: Nutritional stimulation of cholecystokinin receptors inhibits inflammation via the vagus nerve. J Exp Med 2005; 202: 1023-1029.
    • (2005) J Exp Med , vol.202 , pp. 1023-1029
    • Luyer, M.D.1    Greve, J.W.2    Hadfoune, M.3    Jacobs, J.A.4    Dejong, C.H.5    Buurman, W.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.