Effect of exercise training on sleep apnea: A systematic review and meta-analysis

Respiratory Medicine

Volumn 116, Issue , 2016, Pages 85-92

  Aiello, Kenneth D ^a   Caughey, William G ^a   Nelluri, Bhargava ^b   Sharma, Ashwini ^b   Mookadam, Farouk ^b   Mookadam, Martina ^b  

^a ARIZONA STATE UNIVERSITY   (United States)

^b MAYO CLINIC   (United States)

Author keywords

Aerobic exercise; Continuous positive airway pressure; Exercise; Exercise program; Meta analysis; Obstructive sleep apnea; Sleep apnea; Systematic review

Indexed keywords

ADULT; APNEA HYPOPNEA INDEX; BODY MASS; EXERCISE; HUMAN; META ANALYSIS; PRIORITY JOURNAL; REVIEW; SLEEP DISORDERED BREATHING; SYSTEMATIC REVIEW; TREATMENT DURATION; TREATMENT OUTCOME; COMPLICATION; DEVICES; FEMALE; KINESIOTHERAPY; MALE; MIDDLE AGED; OBSERVATIONAL STUDY; PHYSIOLOGY; POLYSOMNOGRAPHY; POSITIVE END EXPIRATORY PRESSURE; PROCEDURES; RANDOMIZED CONTROLLED TRIAL (TOPIC); SEVERITY OF ILLNESS INDEX;

ADULT; CONTINUOUS POSITIVE AIRWAY PRESSURE; EXERCISE; EXERCISE THERAPY; FEMALE; HUMANS; MALE; MIDDLE AGED; OBSERVATIONAL STUDIES AS TOPIC; POLYSOMNOGRAPHY; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SEVERITY OF ILLNESS INDEX; SLEEP APNEA, OBSTRUCTIVE;

EID: 84971434673     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2016.05.015     Document Type: Article

References (68)

1. S.T. Kuna, and G. Sant'Ambrogio PAthophysiology of upper airway closure during sleep JAMA 266 1991 1384 1389
2. K.A. Myers, M. Mrkobrada, and D.L. Simel Does this patient have obstructive sleep apnea?: the rational clinical examination systematic review JAMA 310 2013 731 741
3. J. Nahmias, M. Kirschner, and M.S. Karetzky Weight loss and OSA and pulmonary function in obesity N. J. Med. 90 1993 48 53
4. M. Kansanen, E. Vanninen, A. Tuunainen, P. Pesonen, V. Tuononen, J. Hartikainen, and et al. The effect of a very low-calorie diet-induced weight loss on the severity of obstructive sleep apnoea and autonomic nervous function in obese patients with obstructive sleep apnoea syndrome Clin. Physiol. 18 1998 377 385
5. P. Cortelli, P. Parchi, E. Sforza, M. Contin, G. Pierangeli, G. Barletta, and et al. Cardiovascular autonomic dysfunction in normotensive awake subjects with obstructive sleep apnoea syndrome Clin. Auton. Res. 4 1994 57 62
6. C. Sachs, and L. Kaijser Autonomic regulation of cardiopulmonary functions in sleep apnea syndrome and narcolepsy Sleep 5 1982 227 238
7. A.M. Shamsuzzaman, B.J. Gersh, and V.K. Somers Obstructive sleep apnea: implications for cardiac and vascular disease JAMA 290 2003 1906 1914
8. M.H. Araghi, Y.-F. Chen, A. Jagielski, S. Choudhury, D. Banerjee, S. Hussain, and et al. Effectiveness of lifestyle interventions on obstructive sleep apnea (OSA): systematic review and meta-analysis Sleep 36 10 2013 Oct 1 1553 1562 10.5665/sleep.3056 1562A-1562E
9. A.M. Sawyer, N.S. Gooneratne, C.L. Marcus, D. Ofer, K.C. Richards, and T.E. Weaver A systematic review of CPAP adherence across age groups: clinical and empiric insights for developing CPAP adherence interventions Sleep. Med. Rev. 15 2011 343 356
10. A. Mehta, J. Qian, P. Petocz, M.A. Darendeliler, and P.A. Cistulli A randomized, controlled study of a mandibular advancement splint for obstructive sleep apnea Am. J. Respir. Crit. Care Med. 163 2001 1457 1461
11. R. Osullivan, D. Hillman, R. Mateljan, C. Pantin, and K. Finucane Mandibular advancement splint - an appliance to treat snoring and obstructive sleep-apnea Am. J. Respir. Crit. Care Med. 151 1995 194 198
12. C. Papandreou, S.E. Schiza, I. Bouloukaki, C.M. Hatzis, A.G. Kafatos, N.M. Siafakas, and et al. Effect of Mediterranean diet versus prudent diet combined with physical activity on OSAS: a randomised trial Eur. Respir. J. 39 2012 1398 1404
13. H. Buchwald, Y. Avidor, E. Braunwald, M.D. Jensen, W. Pories, K. Fahrbach, and et al. Bariatric surgery: a systematic review and meta-analysis JAMA J Am. Med. Assoc. 292 2004 1724 1737
14. I. Charuzi, P. Lavie, J. Peiser, and R. Peled Bariatric surgery in morbidly obese sleep-apnea patients - short-term and long-term follow-up Am. J. Clin. Nutr. 55 1992 S594-S6
15. J.B. Dixon, L.M. Schachter, P.E. O'Brien, and et al. Surgical vs conventional therapy for weight loss treatment of obstructive sleep apnea: a randomized controlled trial JAMA 308 2012 1142 1149
16. T.D. Latshang, Y. Nussbaumer-Ochsner, R.M. Henn, and et al. Effect of acetazolamide and autocpap therapy on breathing disturbances among patients with obstructive sleep apnea syndrome who travel to altitude: a randomized controlled trial JAMA 308 2012 2390 2398
17. K.P. Strohl, M.J. Hensley, N.A. Saunders, S.M. Scharf, R. Brown, R.H. Ingram, and et al. PRogesterone administration and progressive sleep apneas JAMA 245 1981 1230 1232
18. D. White, C. Zwillich, C. Pickett, N. Douglas, L. Findley, and J. Weil Central sleep-apnea - improvement with acetazolamide therapy Arch. Intern Med. 142 1982 1816 1819
19. C. Chai-Coetzer, N.A. Antic, L. Rowland, and et al. Primary care vs specialist sleep center management of obstructive sleep apnea and daytime sleepiness and quality of life: a randomized trial JAMA 309 2013 997 1004
20. A.G. Elshaug, J.R. Moss, A.M. Southcott, and J.E. Hiller Redefining success in airway surgery for obstructive sleep apnea: a meta analysis and synthesis of the evidence Sleep 30 2007 461 467
21. H.-C. Lin, M. Friedman, H.-W. Chang, and B. Gurpinar The efficacy of multilevel surgery of the upper airway in adults with obstructive sleep apnea/hypopnea syndrome Laryngoscope 118 2008 902 908
22. G. Sampol, X. Muñoz, M.T. Sagalés, S. Martí, A. Roca, M. Dolors de la Calzada, and et al. Long-term efficacy of dietary weight loss in sleep apnoea/hypopnoea syndrome Eur. Respir. J. 12 1998 1156 1159
23. P.M. Suratt, R.F. McTier, L.J. Findley, S.L. Pohl, and S.C. Wilhoit Effect of very-low-calorie diets with weight loss on obstructive sleep apnea Am. J. Clin. Nutr. 56 1992 182S-4S
24. G. Clark, D. Arand, E. Chung, and D. Tong Effect of anterior mandibular positioning on obstructive sleep-apnea Am. Rev. Respir. Dis. 147 1993 624 629
25. S. Alves Eda, C. Ackel-D'Elia, G.P. Luz, T.C.A. Cunha, G. Carneiro, S. Tufik, and et al. Does physical exercise reduce excessive daytime sleepiness by improving inflammatory profiles in obstructive sleep apnea patients? Sleep. Breath. 17 2013 505 510
26. S.R. Pendharkar, W.H. Tsai, N.D. Eves, G.T. Ford, and W.J. Davidson CPAP increases exercise tolerance in obese subjects with obstructive sleep apnea Respir. Med. 105 2011 1565 1571
27. K. Ucok, A. Aycicek, M. Sezer, A. Genc, M. Akkaya, V. Caglar, and et al. Aerobic and anaerobic exercise capacities in obstructive sleep apnea and associations with subcutaneous fat distributions Lung 187 2009
28. T.E. Vanhecke, B.A. Franklin, S.C. Ajluni, R.B. Sangal, and P.A. McCullough Cardiorespiratory fitness and sleep-related breathing disorders Expert Rev. Cardiovasc Ther. 6 2008 745 758
29. S.D. West, M. Kohler, D.J. Nicoll, and J.R. Stradling The effect of continuous positive airway pressure treatment on physical activity in patients with obstructive sleep apnoea: a randomised controlled trial Sleep. Med. 10 2009 1056 1058
30. Sigal RJ, Kenny Gp Fau - Boule NG, Boule Ng Fau - Wells GA, Wells Ga Fau - Prud'homme D, Prud'homme D Fau - Fortier M, Fortier M Fau - Reid RD, et al. Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes: a randomized trial.
31. Vanhees L, Rauch B Fau - Piepoli M, Piepoli M Fau - van Buuren F, van Buuren F Fau - Takken T, Takken T Fau - Borjesson M, Borjesson M Fau - Bjarnason-Wehrens B, et al. Importance of characteristics and modalities of physical activity and exercise in the management of cardiovascular health in individuals with cardiovascular disease (Part III).
32. Lackland DT, Voeks JH. Metabolic syndrome and hypertension: regular exercise as part of lifestyle management.
33. Clark JE. Diet, exercise or diet with exercise: comparing the effectiveness of treatment options for weight-loss and changes in fitness for adults (18-65 years old) who are overfat, or obese; systematic review and meta-analysis.
34. Punjabi NM. The epidemiology of adult obstructive sleep apnea.
35. K.M. Awad, A. Malhotra, J.H. Barnet, S.F. Quan, and P.E. Peppard Exercise is associated with a reduced incidence of sleep-disordered breathing Am. J. Med. 125 2012 485 490
36. I.H. Iftikhar, C.E. Kline, and S.D. Youngstedt Effects of exercise training on sleep apnea: a meta-analysis Lung 192 2014 175 184
37. P.E. Peppard, and T. Young Exercise and sleep-disordered breathing: an association independent of body habitus Sleep 27 2004 480 484
38. M.-A. Thomasouli, E.M. Brady, M.J. Davies, A.P. Hall, K. Khunti, D.H. Morris, and et al. The impact of diet and lifestyle management strategies for obstructive sleep apnoea in adults: a systematic review and meta-analysis of randomised controlled trials Sleep Breath. 17 2013 925 935
39. A. Anandam, M. Akinnusi, T. Kufel, J. Porhomayon, and A.A. El-Solh Effects of dietary weight loss on obstructive sleep apnea: a meta-analysis Sleep. Breath. 17 2013 227 234
40. L.J. Mitchell, Z.E. Davidson, M. Bonham, D.M. O'Driscoll, G.S. Hamilton, and H. Truby Weight loss from lifestyle interventions and severity of sleep apnoea: a systematic review and meta-analysis Sleep. Med. 15 2014 1173 1183
41. J. Shneerson, and J. Wright Lifestyle modification for obstructive sleep apnoea Cochrane Database Syst. Rev. 2001
42. J.F. Norman, S.G. Von Essen, R.H. Fuchs, and M. McElligott Exercise training effect on obstructive sleep apnea syndrome Sleep. Res. Online 3 2000 121 129
43. A.R. Jadad, R.A. Moore, D. Carroll, C. Jenkinson, D.J. Reynolds, D.J. Gavaghan, and et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin. Trials 17 1996 1 12
44. M. Borenstein, L.V. Hedges, J. Higgins, and H.R. Rothstein A basic introduction to fixed-effect and random-effects models for meta-analysis Res. Synth. Methods 1 2010 97 111
45. J.P.T. Higgins, S.G. Thompson, J.J. Deeks, and D.G. Altman Measuring inconsistency in meta-analyses BMJ 327 2003 557 560
46. J.A. Sterne, and M. Egger Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis J. Clin. Epidemiol. 54 2001 1046 1055
47. J.A.C. Sterne, M. Egger, and G.D. Smith Investigating and dealing with publication and other biases in meta-analysis BMJ 323 2001 101 105
48. A. Liberati, D.G. Altman, J. Tetzlaff, C. Mulrow, P.C. Gøtzsche, J.P.A. Ioannidis, and et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration PLoS Med. 6 2009 e1000100
49. D.F. Stroup, J.A. Berlin, S.C. Morton, and et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting JAMA 283 2000 2008 2012
50. J. Lau, J.P. Ioannidis, and C.H. Schmid Quantitative synthesis in systematic reviews Ann. Intern Med. 127 1997 820 826
51. C. Ackel-D'Elia, A.C. da Silva, R.S. Silva, E. Truksinas, B.S. Sousa, S. Tufik, and et al. Effects of exercise training associated with continuous positive airway pressure treatment in patients with obstructive sleep apnea syndrome Sleep. Breath. 16 2012 723 735
52. D.A. Cavagnolli, A.M. Esteves, C. Ackel-D'Elia, M.Y. Maeda, A.P. de Faria, S. Tufik, and et al. Aerobic exercise does not change C-reactive protein levels in non-obese patients with obstructive sleep apnoea Eur. J. Sport Sci. 14 Suppl. 1 2014 S142 S147
53. K.C. Guimarães, L.F. Drager, P.R. Genta, B.F. Marcondes, and G. Lorenzi-Filho Effects of oropharyngeal exercises on patients with moderate obstructive sleep apnea syndrome Am. J. Respir. Crit. Care Med. 179 2009 962 966
54. C.E. Kline, E.P. Crowley, G.B. Ewing, J.B. Burch, S.N. Blair, J.L. Durstine, and et al. The effect of exercise training on obstructive sleep apnea and sleep quality: a randomized controlled trial Sleep 34 2011 1631 1640
55. N.C. Netzer, J.J. Hoegel, D. Loube, C.M. Netzer, B. Hay, R. Alvarez-Sala, and et al. Prevalence of symptoms and risk of sleep apnea in primary care CHEST 124 2003 1406
56. T.C.B. Schütz, T.C.A. Cunha, T. Moura-Guimaraes, G.P. Luz, C. Ackel-D'Elia, S. Alves Eda, and et al. Comparison of the effects of continuous positive airway pressure, oral appliance and exercise training in obstructive sleep apnea syndrome Clinics (Sao Paulo) 68 2013 1168 1174
57. Y.S. Sengul, S. Ozalevli, I. Oztura, O. Itil, and B. Baklan The effect of exercise on obstructive sleep apnea: a randomized and controlled trial Sleep. Breath. 15 2011 49 56
58. P. Armitage, G. Berry, and J.N.S. Matthews Statistical Methods in Medical Research 2008 John Wiley & Sons
59. V. Giebelhaus, K.P. Strohl, W. Lormes, M. Lehmann, and N. Netzer Physical exercise as an adjunct therapy in sleep apnea-an open trial Sleep. Breath. 4 2000 173 176
60. T. Young, P.E. Peppard, and D.J. Gottlieb Epidemiology of obstructive sleep apnea - a population health perspective Am. J. Respir. Crit. Care Med. 165 2002 1217 1239
61. D.L. Greenburg, C.J. Lettieri, and A.H. Eliasson Effects of surgical weight loss on measures of obstructive sleep apnea: a meta-analysis Am. J. Med. 122 2009 535 542
62. P. Nerfeldt, B.Y. Nilsson, L. Mayor, J. Udden, and D. Friberg A two-year weight reduction program in obese sleep apnea patients J. Clin. Sleep. Med. 6 2010 479 486
63. R.E. Slavin Best evidence synthesis: an intelligent alternative to meta-analysis J. Clin. Epidemiol. 48 1995 9 18
64. J.S. Valbuza, M.M. de Oliveira, C.F. Conti, L.B.F. Prado, L.B.C. de Carvalho, and G.F. do Prado Methods for increasing upper airway muscle tonus in treating obstructive sleep apnea: systematic review Sleep. Breath. 14 2010 299 305
65. S. Borzak, and P.M. Ridker Discordance between meta-analyses and large-scale randomized, controlled trials. Examples from the management of acute myocardial infarction Ann. Intern Med. 123 1995 873 877
66. M.D. Flather, M.E. Farkouh, J.M. Pogue, and S. Yusuf Strengths and limitations of meta-analysis: larger studies may be more reliable Control Clin. Trials 18 1997 568 579 discussion 661-6
67. J. LeLorier, G. Grégoire, A. Benhaddad, J. Lapierre, and F. Derderian Discrepancies between meta-analyses and subsequent large randomized, controlled trials N. Engl. J. Med. 337 1997 536 542
68. N. Terrin, C.H. Schmid, and J. Lau In an empirical evaluation of the funnel plot, researchers could not visually identify publication bias J. Clin. Epidemiol. 58 2005 894 901