CPAP increases exercise tolerance in obese subjects with obstructive sleep apnea

Respiratory Medicine

Volumn 105, Issue 10, 2011, Pages 1565-1571

  Pendharkar, Sachin R ^a   Tsai, Willis H ^a   Eves, Neil D ^b   Ford, Gordon T ^a   Davidson, Warren J ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Continuous positive airway pressure; Dyspnea; Exercise; Obesity; Obstructive sleep apnea

Indexed keywords

ADULT; AGED; APNEA HYPOPNEA INDEX; ARTICLE; BODY MASS; CLINICAL ARTICLE; DYSPNEA; EXERCISE TOLERANCE; FATIGUE; FEMALE; HUMAN; LUNG FUNCTION; MALE; OBESITY; OXYGEN CONSUMPTION; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; QUESTIONNAIRE; SLEEP APNEA SYNDROME; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; ANALYSIS OF VARIANCE; CONTINUOUS POSITIVE AIRWAY PRESSURE; EXERCISE TOLERANCE; HUMANS; MALE; MIDDLE AGED; OBESITY; OXYGEN CONSUMPTION; PILOT PROJECTS; POLYSOMNOGRAPHY; QUESTIONNAIRES; SLEEP APNEA, OBSTRUCTIVE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 80051894064     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2011.06.007     Document Type: Article

References (36)

1. D.C. Lau, J.D. Douketis, K.M. Morrison, I.M. Hramiak, A.M. Sharma, E. Ur Obesity Canada Clinical Practice Guidelines Expert Panel Canadian clinical practice guidelines on the management and prevention of obesity in adults and children Can Med Assoc J 176 8 2006 S1 S13 [summary] 2007, Apr 10
2. K.F. Adams, A. Schatzkin, T.B. Harris, V. Kipnis, T. Mouw, and R. Ballard-Barbash Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old N Engl J Med 355 8 2006, Aug 24 763 778 (Pubitemid 44285582)
3. T. Young, P.E. Peppard, and S. Taheri Excess weight and sleep-disordered breathing J Appl Physiol 99 4 2005, Oct 1592 1599 (Pubitemid 43014371)
4. A. Naimark, and R.M. Cherniack Compliance of the respiratory system and its components in health and obesity J Appl Physiol 15 3 1960 377
5. F. Zerah, A. Harf, L. Perlemuter, H. Lorino, A.M. Lorino, and G. Atlan Effects of obesity on respiratory resistance Chest 103 5 1993 1470
6. J.C. Yap, R.A. Watson, S. Gilbey, and N.B. Pride Effects of posture on respiratory mechanics in obesity J Appl Physiol 79 4 1995 1199
7. M.G. Sampson, and K. Grassino Neuromechanical properties in obese patients during carbon dioxide rebreathing Am J Med 75 1 1983, Jul 81 90 (Pubitemid 13060290)
8. A.E. Weyman, R. Davidoff, J. Gardin, T. Ryan, M.S.J. Sutton, and N.J. Weissman Echocardiographic evaluation of pulmonary artery pressure with clinical correlates in predominantly obese adults J Am Soc Echocardiogr 15 5 2002 454 462 (Pubitemid 46002660)
9. S.W. Zarich, G.J. Kowalchuk, M.P. McGuire, P.N. Benotti, E.A. Mascioli, and R.W. Nesto Left ventricular filling abnormalities in asymptomatic morbid obesity Am J Cardiol 68 4 1991, Aug 1 377 381
10. I. Romagnoli, P. Laveneziana, E.M. Clini, P. Palange, G. Valli, and F. de Blasio Role of hyperinflation vs. deflation on dyspnoea in severely to extremely obese subjects Acta Physiol (Oxf) 193 4 2008, Aug 393 402
11. T.G. Babb, K.G. Ranasinghe, L.A. Comeau, T.L. Semon, and B. Schwartz Dyspnea on exertion in obese women: association with an increased oxygen cost of breathing Am J Respir Crit Care Med 178 2 2008, Jul 15 116 123 (Pubitemid 351957769)
12. D.D. Sin, R.L. Jones, and S.F. Man Obesity is a risk factor for dyspnea but not for airflow obstruction Arch Int Med 162 13 2002 1477
13. D.A. Mahler, K. Faryniarz, D. Tomlinson, G.L. Colice, A.G. Robins, E.M. Olmstead, and G.T. O'Connor Impact of dyspnea and physiologic function on general health status in patients with chronic obstructive pulmonary disease Chest 102 2 1992 Aug 395 401
14. S.N. Blair Evidence for success of exercise in weight loss and control Ann Intern Med 119 7 Pt 2 1993, Oct 1 702 706 (Pubitemid 23313693)
15. A. Rosengren, S. Hawken, S. Ounpuu, K. Sliwa, M. Zubaid, and W.A. Almahmeed Association of psychosocial risk factors with risk of acute myocardial infarction in 11119 cases and 13648 controls from 52 countries (the INTERHEART study): case-control study Lancet 364 9438 2004 953 962 (Pubitemid 39208456)
16. K. Ucok, A. Aycicek, M. Sezer, A. Genc, M. Akkaya, and V. Caglar Aerobic and anaerobic exercise capacities in obstructive sleep apnea and associations with subcutaneous fat distributions Lung 187 1 2009 29 36
17. T.E. Vanhecke, B.A. Franklin, K.C. Zalesin, R.B. Sangal, A.T. deJong, V. Agrawal, and P.A. McCullough Cardiorespiratory fitness and obstructive sleep apnea syndrome in morbidly obese patients Chest 134 3 2008, Sep 539 545
18. T.A. Hargens, S.G. Guill, A. Aron, D. Zedalis, J.M. Gregg, S.M. Nickols-Richardson, and W.G. Herbert Altered ventilatory responses to exercise testing in young adult men with obstructive sleep apnea Respir Med 103 7 2009, Jul 1063 1069
19. M.T. Maeder, P. Ammann, H. Rickli, O.D. Schoch, W. Korte, and C. Hürny N-terminal pro-B-type natriuretic peptide and functional capacity in patients with obstructive sleep apnea Sleep Breath 12 1 2008, Mar 7 16
20. A.S. Kaleth, T.W. Chittenden, B.J. Hawkins, T.A. Hargens, S.G. Guill, and D. Zedalis Unique cardiopulmonary exercise test responses in overweight middle-aged adults with obstructive sleep apnea Sleep Med 8 2 2007, Mar 160 168 (Pubitemid 46206838)
21. A. Alonso-Fernández, F. García-Río, M.A. Arias, O. Mediano, J.M. Pino, I. Martínez, and J. Villamor Obstructive sleep apnoea-hypoapnoea syndrome reversibly depresses cardiac response to exercise Eur Heart J 27 2 2006, Jan 207 215 (Pubitemid 43069039)
22. T. Przybyłowski, P. Bielicki, M. Kumor, K. Hildebrand, M. Maskey-Warzechowska, P. Korczyński, and R. Chazan Exercise capacity in patients with obstructive sleep apnea syndrome J Physiol Pharmacol 5 Pt 2 2007, Nov;58 563 574 (Pubitemid 351346706)
23. D. Vanuxem, M. Badier, C. Guillot, S. Delpierre, F. Jahjah, and P. Vanuxem Impairment of muscle energy metabolism in patients with sleep apnoea syndrome Respir Med 91 9 1997, Oct 551 557 (Pubitemid 27397297)
24. D. Edward Shifflett Jr., E.W. Walker, J.M. Gregg, D. Zedalis, and W.G. Herbert Effects of short-term PAP treatment on endurance exercise performance in obstructive sleep apnea patients Sleep Med 2 2 2001 145 151 (Pubitemid 32258044)
25. C.C. Lin, C.K. Lin, K.M. Wu, and C.S. Chou Effect of treatment by Nasal CPAP on cardiopulmonary exercise test in obstructive sleep apnea syndrome Lung 182 4 2004 199 212
26. American Thoracic Society, and American College of Chest Physicians ATS/ACCP statement on cardiopulmonary exercise testing Am J Respir Crit Care Med 167 2 2003, Jan 15 211 277
27. G.A. Borg Psychophysical bases of perceived exertion Med Sci Sports Exerc 14 5 1982 377 381 (Pubitemid 13215050)
28. G. Godin, and R.J. Shephard A simple method to assess exercise behavior in the community Can J Appl Sport Sci 10 3 1985, Sep 141 146
29. D. Ofir, P. Laveneziana, K.A. Webb, and D.E. O'Donnell Ventilatory and perceptual responses to cycle exercise in obese women J Appl Physiol 102 6 2007, Jun 2217 2226 (Pubitemid 47080753)
30. W. Pankow, T. Podszus, T. Gutheil, T. Penzel, J. Peter, and P. Von Wichert Expiratory flow limitation and intrinsic positive end-expiratory pressure in obesity J Appl Physiol 85 4 1998, Oct 1236 1243 (Pubitemid 28465047)
31. R.L. Jones, and M.M. Nzekwu The effects of body mass index on lung volumes Chest 130 3 2006, Sep 827 833 (Pubitemid 44423616)
32. M. Coussa, S. Proietti, P. Schnyder, P. Frascarolo, M. Suter, D.R. Spahn, and L. Magnusson Prevention of atelectasis formation during the induction of general anesthesia in morbidly obese patients Anesth Analg 98 5 2004 1491
33. N. Okuda, T. Ito, N. Emura, M. Suwa, T. Hayashi, H. Yoneda, and Y. Kitaura Depressed myocardial contractile reserve in patients with obstructive sleep apnea assessed by tissue Doppler imaging with dobutamine stress echocardiography Chest 131 4 2007, Apr 1082 1089 (Pubitemid 46608710)
34. A. Romero-Corral, V.K. Somers, P.A. Pellikka, E.J. Olson, K.R. Bailey, and J. Korinek Decreased right and left ventricular myocardial performance in obstructive sleep apnea Chest 132 6 2007, Dec 1863 1870
35. U.J. Magalang, K. Richards, A. Rt Bmc Fathala, and S.V. Raman Continuous positive airway pressure therapy reduces right ventricular volume in patients with obstructive sleep apnea: a cardiovascular magnetic resonance study J Clin Sleep Med 5 2 2009 110 114
36. C.L. Phillips, B. Yee, Q. Yang, A.T. Villaneuva, J. Hedner, N. Berend, and R. Grunstein Effects of continuous positive airway pressure treatment and withdrawal in patients with obstructive sleep apnea on arterial stiffness and central BP. Chest 134 1 2008, Jul 94 100 (Pubitemid 352008769)