Molecular Genetics of Beauveria bassiana Infection of Insects

Advances in Genetics

Volumn 94, Issue , 2016, Pages 165-249

  Ortiz Urquiza, A ^a   Keyhani, N O ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

Beauveria bassiana; Cuticle degradation; Fungal development and biology; Insect pathology; Molecular genetics; Signal transduction; Stress response; Virulence

Indexed keywords

FUNGAL PROTEIN; VIRULENCE FACTOR;

ANIMAL; BEAUVERIA; GENE EXPRESSION REGULATION; GENETICS; HOST PATHOGEN INTERACTION; INSECT; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PHYSIOLOGICAL STRESS; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; BEAUVERIA; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HOST-PATHOGEN INTERACTIONS; INSECTS; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; VIRULENCE FACTORS;

EID: 84971378277     PISSN: 00652660     EISSN: None     Source Type: Book Series    
DOI: 10.1016/bs.adgen.2015.11.003     Document Type: Article

References (192)

1. Behie S.W., Bidochka M.J. Nutrient transfer in plant-fungal symbioses. Trends in Plant Science 2014, 19:734-740. 10.1016/j.tplants.2014.06.007.
2. Behie S.W., Zelisko P.M., Bidochka M.J. Endophytic insect-parasitic fungi translocate nitrogen directly from insects to plants. Science 2012, 336:1576-1577. 10.1126/Science.1222289.
3. Bidochka M.J., Clark D.C., Lewis M.W., Keyhani N.O. Could insect phagocytic avoidance by entomogenous fungi have evolved via selection against soil amoeboid predators?. Microbiology-Sgm 2010, 156:2164-2171.
4. Bidochka M.J., Khachatourians G.G. Purification and properties of an extracellular protease produced by the entomopathogenic fungus Beauveria bassiana. Applied and Environmental Microbiology 1987, 53:1679-1684.
5. Bidochka M.J., Khachatourians G.G. Regulation of extracellular protease in the entomopathogenic fungus Beauveria bassiana. Experimental Mycology 1988, 12:161-168. 10.1016/0147-5975(88)90005-9.
6. Bidochka M.J., Khachatourians G.G. Identification of Beauveria bassiana extracellular protease as a virulence factor in pathogenicity toward the migratory grasshopper, Melanoplus sanguinipes. Journal of Invertebrate Pathology 1990, 56:362-370.
7. Bidochka M.J., Khachatourians G.G. Basic proteases of entomopathogenic fungi differ in their adsorption properties to insect cuticle. Journal of Invertebrate Pathology 1994, 64:26-32. 10.1006/jipa.1994.1064.
8. Bidochka M.J., Menzies F.V., Kamp A.M. Genetic groups of the insect-pathogenic fungus Beauveria bassiana are associated with habitat and thermal growth preferences. Archives of Microbiology 2002, 178:531-537. 10.1007/s00203-002-0490-7.
9. Biswas C., Dey P., Satpathy S., Satya P. Establishment of the fungal entomopathogen Beauveria bassiana as a season long endophyte in jute (Corchorus olitorius) and its rapid detection using SCAR marker. BioControl 2012, 57:565-571. 10.1007/S10526-011-9424-0.
10. Boomsma J.J., Jensen A.B., Meyling N.V., Eilenberg J. Evolutionary interaction networks of insect pathogenic fungi. Annual Review of Entomology 2014, 59:467-485. 10.1146/annurev-ento-011613-162054.
11. Boucias D., Pendland J. Attachment of mycopathogens to cuticle. The fungal spore and disease initiation in plants and animals 1991, 101-127. Plenum Press, New York, NY. G.T. Cole, H.C. Hoch (Eds.).
12. Boucias D.G., Mazet I., Pendland J., Hung S.Y. Comparative-analysis of the in-vivo and in-vitro metabolites produced by the entomopathogen Beauveria-bassiana. Canadian Journal of Botany 1995, 73:S1092-S1099.
13. Boucias D.G., Pendland J.C., Latge J.P. Nonspecific factors involved in attachment of entomopathogenic deuteromycetes to host insect cuticle. Applied and Environmental Microbiology 1988, 54:1795-1805.
14. Brewer D., Jen W.C., Jones G.A., Taylor A. The antibacterial activity of some naturally occurring 2,5-dihydroxy-1,4-benzoquinones. Canadian Journal of Microbiology 1984, 30:1068-1072.
15. Brownbridge M., Costa S., Jaronski S.T. Effects of in vitro passage of Beauveria bassiana on virulence to Bemisia argentifolii. Journal of Invertebrate Pathology 2001, 77:280-283.
16. Brownbridge M., Reay S.D., Nelson T.L., Glare T.R. Persistence of Beauveria bassiana (Ascomycota: Hypocreales) as an endophyte following inoculation of radiata pine seed and seedlings. Biological Control 2012, 61:194-200. 10.1016/J.Biocontrol.2012.01.002.
17. Chantasingh D., Kitikhun S., Keyhani N.O., Boonyapakron K., Thoetkiattikul H., Pootanakit K., et al. Identification of catalase as an early up-regulated gene in Beauveria bassiana and its role in entomopathogenic fungal virulence. Biological Control 2013, 67:85-93. 10.1016/J.Biocontrol.2013.08.004.
18. Charnley A.K. Fungal pathogens of insects: cuticle degrading enzymes and toxins. Advances in Botanical Research 2003, 40:241-321. 10.1016/S0065-2296(05)40006-3.
19. Chen Y., Zhu J., Ying S.H., Feng M.G. The GPI-anchored protein Ecm33 is vital for conidiation, cell wall integrity, and multi-stress tolerance of two filamentous entomopathogens but not for virulence. Applied Microbiology and Biotechnology 2014, 10.1007/s00253-014-5577-y.
20. Chen Y., Zhu J., Ying S.H., Feng M.G. Three mitogen-activated protein kinases required for cell wall integrity contribute greatly to biocontrol potential of a fungal entomopathogen. Plos One 2014, 9:e87948. 10.1371/journal.pone.0087948.
21. Cho E.M., Boucias D., Keyhani N.O. EST analysis of cDNA libraries from the entomopathogenic fungus Beauveria (Cordyceps) bassiana. II. Fungal cells sporulating on chitin and producing oosporein. Microbiology-Sgm 2006, 152:2855-2864.
22. Cho E.M., Kirkland B.H., Holder D.J., Keyhani N.O. Phage display cDNA cloning and expression analysis of hydrophobins from the entomopathogenic fungus Beauveria (Cordyceps) bassiana. Microbiology-Sgm 2007, 153:3438-3447.
23. Cho E.M., Liu L., Farmerie W., Keyhani N.O. EST analysis of cDNA libraries from the entomopathogenic fungus Beauveria (Cordyceps) bassiana. I. Evidence for stage-specific gene expression in aerial conidia, in vitro blastospores and submerged conidia. Microbiology-Sgm 2006, 152:2843-2854.
24. Cole R.J., Kirksey J.W., Cutler H.G., Davis E.E. Toxic effects of oosporein from Chaetomium-Trilaterale. Journal of Agricultural and Food Chemistry 1974, 22:517-520. 10.1021/Jf60193a049.
25. Corina D.L., Munday K.A. Studies on polyol function in Aspergillus clavatus - role for mannitol and ribitol. Journal of General Microbiology 1971, 69:221.
26. de Crecy E., Jaronski S., Lyons B., Lyons T.J., Keyhani N.O. Directed evolution of a filamentous fungus for thermotolerance. BMC Biotechnology 2009, 9.
27. Crespo R., Juarez M.P., Dal Bello G.M., Padin S., Fernandez G.C., Pedrini N. Increased mortality of Acanthoscelides obtectus by alkane-grown Beauveria bassiana. BioControl 2002, 47:685-696.
28. 2+ ATPases in Saccharomyces cerevisiae. Molecular and Cellular Biology 1996, 16:2226-2237.
29. Dias B.A., Neves P.M.O.J., Furlaneto-Maia L., Furlaneto M.C. Cuticle-degrading proteases produced by the entomopathogenic fungus Beauveria bassiana in the presence of coffee berry borer cuticle. Brazilian Journal of Microbiology 2008, 39:301-306.
30. Donatti A.C., Furlaneto-Maia L., Fungaro M.H.P., Furlaneto M.C. Production and regulation of cuticle-degrading proteases from Beauveria bassiana in the presence of Rhammatocerus schistocercoides cuticle. Current Microbiology 2008, 56:256-260.
31. Eleutherio E., Panek A., De Mesquita J.F., Trevisol E., Magalhaes R. Revisiting yeast trehalose metabolism. Current Genetics 2015, 61:263-274. 10.1007/s00294-014-0450-1.
32. Eley K.L., Halo L.M., Song Z.S., Powles H., Cox R.J., Bailey A.M., et al. Biosynthesis of the 2-pyridone tenellin in the insect pathogenic fungus Beauveria bassiana. ChemBioChem 2007, 8:289-297.
33. Fan Y., Ortiz-Urquiza A., Garrett T., Pei Y., Keyhani N.O. Involvement of a caleosin in lipid storage, spore dispersal, and virulence in the entomopathogenic filamentous fungus, Beauveria bassiana. Environmental Microbiology 2015, 10.1111/1462-2920.12990.
34. Fan Y., Ortiz-Urquiza A., Kudia R.A., Keyhani N.O. A fungal homologue of neuronal calcium sensor-1, Bbcsa1, regulates extracellular acidification and contributes to virulence in the entomopathogenic fungus Beauveria bassiana. Microbiology 2012, 158:1843-1851. 10.1099/mic.0.058867-0.
35. Fan Y., Zhang S., Kruer N., Keyhani N.O. High-throughput insertion mutagenesis and functional screening in the entomopathogenic fungus Beauveria bassiana. Journal of Invertebrate Pathology 2011, 106:274-279.
36. Fan Y.H., Fang W.G., Guo S.J., Pei X.Q., Zhang Y.J., Xiao Y.H., et al. Increased insect virulence in Beauveria bassiana strains overexpressing an engineered chitinase. Applied and Environmental Microbiology 2007, 73:295-302. 10.1128/Aem.01974-06.
37. Fan Y.H., Fang W.G., Xiao Y.H., Yang X.Y., Zhang Y.J., Bidochka M.J., et al. Directed evolution for increased chitinase activity. Applied Microbiology and Biotechnology 2007, 76:135-139. 10.1007/s00253-007-0996-7.
38. Fang W.G., Feng J., Fan Y.H., Zhang Y.J., Bidochka M.J., Leger R.J.S., et al. Expressing a fusion protein with protease and chitinase activities increases the virulence of the insect pathogen Beauveria bassiana. Journal of Invertebrate Pathology 2009, 102:155-159. 10.1016/j.jip.2009.07.013.
39. Fang W.G., Leng B., Xiao Y.H., Jin K., Ma J.C., Fan Y.H., et al. Cloning of Beauveria bassiana chitinase gene Bbchit1 and its application to improve fungal strain virulence. Applied and Environmental Microbiology 2005, 71:363-370.
40. Fang W.G., Scully L.R., Zhang L., Pei Y., Bidochka M.J. Implication of a regulator of G protein signalling (BbRGS1) in conidiation and conidial thermotolerance of the insect pathogenic fungus Beauveria bassiana. FEMS Microbiology Letters 2008, 279:146-156. 10.1111/j.1574-6968.2007.00978.x.
41. Fang W.G., Zhang Y.J., Yang X.Y., Zheng X.L., Duan H., Li Y., et al. Agrobacterium tumefaciens-mediated transformation of Beauveria bassiana using an herbicide resistance gene as a selection marker. Journal of Invertebrate Pathology 2004, 85:18-24.
42. Feng P., Shang Y.F., Cen K., Wang C.S. Fungal biosynthesis of the bibenzoquinone oosporein to evade insect immunity. Proceedings of the National Academy of Sciences of the United States of America 2015, 112:11365-11370. 10.1073/pnas.1503200112.
43. Gibson D.M., Donzelli B.G., Krasnoff S.B., Keyhani N.O. Discovering the secondary metabolite potential encoded within entomopathogenic fungi. Natural Product Reports 2014, 31:1287-1305. 10.1039/c4np00054d.
44. Glare T., Caradus J., Gelernter W., Jackson T., Keyhani N., Kohl J., et al. Have biopesticides come of age?. Trends in Biotechnology 2012, 30:250-258. 10.1016/j.tibtech.2012.01.003.
45. Goettel M.S., Hajek A.E., Siegel J.P., Evans H.C. Safety of fungal biocontrol agents. Fungi as biocontrol agents, progress, problems, and potential 2001, 347-375. CAB International, Wallingford, UK. T.M. Butt, C. Jackson, N. Magan (Eds.).
46. Guan Y., Wang D.Y., Ying S.H., Feng M.G. A novel Ras GTPase (Ras3) regulates conidiation, multi-stress tolerance and virulence by acting upstream of Hog1 signaling pathway in Beauveria bassiana. Fungal Genetics and Biology 2015, 82:85-94. 10.1016/j.fgb.2015.07.002.
47. Guerri-Agulloo B., Gomez-Vidal S., Asensio L., Barranco P., Lopez-Llorca L.V. Infection of the red palm weevil (Rhynchophorus ferrugineus) by the entomopathogenic fungus Beauveria bassiana: a SEM study. Microscopy Research and Technique 2010, 73:714-725. 10.1002/jemt.20812.
48. Gupta S.C., Leathers T.D., Elsayed G.N., Ignoffo C.M. Insect cuticle-degrading enzymes from the entomogenous fungus Beauveria bassiana. Experimental Mycology 1992, 16:132-137. 10.1016/0147-5975(92)90019-N.
49. Gupta S.C., Leathers T.D., Elsayed G.N., Ignoffo C.M. Relationships among enzyme-activities and virulence parameters in Beauveria bassiana infections of Galleria mellonella and Trichoplusia ni. Journal of Invertebrate Pathology 1994, 64:13-17. 10.1006/jipa.1994.1062.
50. Hajek A.E., Delalibera I. Fungal pathogens as classical biological control agents against arthropods. BioControl 2010, 55:147-158.
51. Halo L.M., Heneghan M.N., Yakasai A.A., Song Z., Williams K., Bailey A.M., et al. Late stage oxidations during the biosynthesis of the 2-pyridone tenellin in the entomopathogenic fungus Beauveria bassiana. Journal of the American Chemical Society 2008, 130:17988-17996.
52. Halo L.M., Marshall J.W., Yakasai A.A., Song Z., Butts C.P., Crump M.P., et al. Authentic heterologous expression of the tenellin iterative polyketide synthase nonribosomal peptide synthetase requires coexpression with an enoyl reductase. ChemBioChem 2008, 9:585-594.
53. He P.H., Wang X.X., Chu X.L., Feng M.G., Ying S.H. RNA sequencing analysis identifies the metabolic and developmental genes regulated by BbSNF1 during conidiation of the entomopathogenic fungus Beauveria bassiana. Current Genetics 2015, 61:143-152. 10.1007/s00294-014-0462-x.
54. He Z., Zhang S., Keyhani N.O., Song Y., Huang S., Pei Y., et al. A novel mitochondrial membrane protein, Ohmm, limits fungal oxidative stress resistance and virulence in the insect fungal pathogen Beauveria bassiana. Environmental Microbiology 2014, 10.1111/1462-2920.12713.
55. Hegedus D.D., Pfeifer T.A., MacPherson J.M., Khachatourians G.G. Cloning and analysis of five mitochondrial tRNA-encoding genes from the fungus Beauveria bassiana. Gene 1991, 109:149-154.
56. Holder D.J., Keyhani N.O. Adhesion of the entomopathogenic fungus Beauveria (Cordyceps) bassiana to substrata. Applied and Environmental Microbiology 2005, 71:5260-5266.
57. Holder D.J., Kirkland B.H., Lewis M.W., Keyhani N.O. Surface characteristics of the entomopathogenic fungus Beauveria (Cordyceps) bassiana. Microbiology-Sgm 2007, 153:3448-3457.
58. 2+ tolerance, multistress responses and virulence of a filamentous entomopathogen. Fungal Genetics and Biology 2014, 73:12-19. 10.1016/j.fgb.2014.09.005.
59. Huang S., He Z., Zhang S., Keyhani N.O., Song Y., Yang J., et al. Interplay between calcineurin and the Slt2 MAP-kinase in mediating cell wall integrity, conidiation, and virulence in the insect fungal pathogen Beauveria bassiana. Fungal Genetic and Biology 2015, 83:78-91.
60. Hult K., Veide A., Gatenbeck S. The distribution of the NADP(H)-regenerating mannitol cycle among fungal species. Archives of Microbiology 1980, 128:253-255. 10.1007/Bf00406168.
61. Humber R.A.C. Usda-ars collection of entomopathogenic fungal cultures (ARSEF). Emerging pests and pathogens research unit RWHCfAaH 2015, (Ithaca, NY).
62. Inglis G.D., Goettel M.S., Butt T.M., Strasser H. Use of hyphomycetous fungi for managing insect pests. Field manual of techniques in invertebrate pathology 2001, 651-679. Kluwer Academic, Netherlands. L.A. Lacey, H.K. Kaya (Eds.).
63. Inglis G.D., Goettel M.S., Johnson D.L. Persistence of the entomopathogenic fungus, Beauveria bassiana, on phylloplanes of crested wheatgrass and alfalfa. Biological Control 1993, 3:258-270.
64. Jackson M.A., Dunlap C.A., Jaronski S.T. Ecological considerations in producing and formulating fungal entomopathogens for use in insect biocontrol. BioControl 2010, 55:129-145.
65. Jaronski S.T. Ecological factors in the inundative use of fungal entomopathogens. BioControl 2010, 55:159-185.
66. Jin K., Zhang Y.J., Fang W.G., Luo Z.B., Zhou Y.H., Pei Y. Carboxylate transporter gene JEN1 from the entomopathogenic fungus Beauveria bassiana is involved in conidiation and virulence. Applied and Environmental Microbiology 2010, 76:254-263.
67. Jin K., Zhang Y.J., Luo Z.B., Xiao Y.H., Fan Y.H., Wu D., et al. An improved method for Beauveria bassiana transformation using phosphinothricin acetlytransferase and green fluorescent protein fusion gene as a selectable and visible marker. Biotechnology Letters 2008, 30:1379-1383.
68. Jin-Zhu X., Bo H., Chang-Sheng Q., Zeng-Zhi L. Sequence and phylogenetic analysis of Beauveria bassiana with mitochondrial genome. Mycosystema 2009, 28:718-723.
69. Jirakkakul J., Cheevadhanarak S., Punya J., Chutrakul C., Senachak J., Buajarern T., et al. Tenellin acts as an iron chelator to prevent iron-generated reactive oxygen species toxicity in the entomopathogenic fungus Beauveria bassiana. FEMS Microbiology Letters 2015, 362. 10.1093/femsle/fnu032.
70. Joshi L., St Leger R.J., Bidochka M.J. Cloning of a cuticle degrading protease from the entomopathogenic fungus, Beauveria bassiana. FEMS Microbiology Letters 1995, 125:211-217.
71. Keyhani N.O., Li X.B., Roseman S. Chitin catabolism in the marine bacterium Vibrio furnissii. Identification and molecular cloning of a chitoporin. Journal of Biological Chemistry 2000, 275:33068-33076.
72. Keyhani N.O., Roseman S. The chitin catabolic cascade in the marine bacterium Vibrio furnissii - molecular cloning, isolation, and characterization of a periplasmic beta-N-acetylglucosaminidase. Journal of Biological Chemistry 1996, 271:33425-33432.
73. Keyhani N.O., Roseman S. The chitin catabolic cascade in the marine bacterium Vibrio furnissii - molecular cloning, isolation, and characterization of a periplasmic chitodextrinase. Journal of Biological Chemistry 1996, 271:33414-33424.
74. Keyhani N.O., Roseman S. Physiological aspects of chitin catabolism in marine bacteria. Biochimica et Biophysica Acta 1999, 1473:108-122.
75. Keyhani N.O., Wang L.X., Lee Y.C., Roseman S. The chitin catabolic cascade in the marine bacterium Vibrio furnissii. Characterization of an N,N'-diacetyl-chitobiose transport system. Journal of Biological Chemistry 1996, 271:33409-33413.
76. Kim H.K., Hoe H.S., Suh D.S., Kang S.C., Hwang C., Kwon S.T. Gene structure and expression of the gene from Beauveria bassiana encoding bassiasin I, an insect cuticle-degrading serine protease. Biotechnology Letters 1999, 21:777-783. 10.1023/A:1005583324654.
77. Kirkland B.H., Cho E.M., Keyhani N.O. Differential susceptibility of Amblyomma maculatum and Amblyomma americanum (Acari: Ixodidea) to the entomopathogenic fungi Beauveria bassiana and Metarhizium anisopliae. Biological Control 2004, 31:414-421.
78. Kirkland B.H., Eisa A., Keyhani N.O. Oxalic acid as a fungal acaracidal virulence factor. Journal of Medical Entomology 2005, 42:346-351.
79. Kirkland B.H., Keyhani N.O. Expression and purification of a functionally active class I fungal hydrophobin from the entomopathogenic fungus Beauveria bassiana in E. coli. Journal of Indusrtrial Microbiology and Biotechnology 2011, 38:327-335.
80. Kirkland B.H., Westwood G.S., Keyhani N.O. Pathogenicity of entomopathogenic fungi Beauveria bassiana and Metarhizium anisopliae to Ixodidae tick species Dermacentor variabilis, Rhipicephalus sanguineus, and Ixodes scapularis. Journal of Medical Entomology 2004, 41:705-711.
81. Kogl F., van Wessem G.C. Analysis concerning pigments of fungi XIV Concerning oosporein, the pigment of Oospora colorans van Beyma. Recueil Des Travaux Chimiques Des Pays-Bas 1944, 63:5-24.
82. Kolattukudy P.E., Rogers L.M., Li D.X., Hwang C.S., Flaishman M.A. Surface signaling in pathogenesis. Proceedings of the National Academy of Sciences of the United States of America 1995, 92:4080-4087.
83. Kucera M. Toxins of entomophagous fungus Beauveria bassiana. 2. Effect of nitrogen sources on formation of toxic protease in submerged culture. Journal of Invertebrate Pathology 1971, 17:211.
84. Kurtti T.J., Keyhani N.O. Intracellular infection of tick cell lines by the entomopathogenic fungus Metarhizium anisopliae. Microbiology-Sgm 2008, 154:1700-1709.
85. Leathers T.D., Gupta S.C., Alexander N.J. Mycopesticides: status, challenges, and potential. Journal of Industrial Microbiology 1993, 12:69-75.
86. Leopold J., Samsinakova A. Quantitative estimation of chitinase and several other enzymes in fungus Beauveria bassiana. Journal of Invertebrate Pathology 1970, 15:34.
87. Lewis M.W., Robalino I.V., Keyhani N.O. Uptake of the fluorescent probe FM4-64 by hyphae and haemolymph-derived in vivo hyphal bodies of the entomopathogenic fungus Beauveria bassiana. Microbiology-Sgm 2009, 155:3110-3120.
88. Li F., Shi H.Q., Ying S.H., Feng M.G. Distinct contributions of one Fe- and two Cu/Zn-cofactored superoxide dismutases to antioxidation, UV tolerance and virulence of Beauveria bassiana. Fungal Genetics and Biology 2015, 81:160-171. 10.1016/j.fgb.2014.09.006.
89. Li F., Shi H.Q., Ying S.H., Feng M.G. WetA and VosA are distinct regulators of conidiation capacity, conidial quality, and biological control potential of a fungal insect pathogen. Applied Microbiology and Biotechnology 2015, 10.1007/s00253-015-6823-7.
90. Li F., Wang Z.L., Zhang L.B., Ying S.H., Feng M.G. The role of three calcineurin subunits and a related transcription factor (Crz1) in conidiation, multistress tolerance and virulence in Beauveria bassiana. Applied Microbiology and Biotechnology 2015, 99:827-840. 10.1007/s00253-014-6124-6.
91. Liao X.G., Fang W.G., Zhang Y.J., Fan Y.H., Wu X.W., Zhou Q., et al. Characterization of a highly active promoter, pBbgpd, in Beauveria bassiana. Current Microbiology 2008, 57:121-126.
92. Liao X.G., Zhang Y.J., Fan Y.H., Ma J.C., Zhou Y.H., Jin D., et al. An ethanol inducible alc system for regulating gene expression in Beauveria bassiana. World Journal of Microbiology & Biotechnology 2009, 25:2065-2069.
93. Liu Q., Li J.G., Ying S.H., Wang J.J., Sun W.L., Tian C.G., et al. Unveiling equal importance of two 14-3-3 proteins for morphogenesis, conidiation, stress tolerance and virulence of an insect pathogen. Environmental Microbiology 2015, 17:1444-1462. 10.1111/1462-2920.12634.
94. Liu Q., Ying S.H., Feng M.G. Characterization of Beauveria bassiana neutral trehalase (BbNTH1) and recognition of crucial stress-responsive elements to control its expression in response to multiple stresses. Microbiological Research 2011, 166:282-293. 10.1016/J.Micres.2010.04.001.
95. Liu Q., Ying S.H., Li J.G., Tian C.G., Feng M.G. Insight into the transcriptional regulation of Msn2 required for conidiation, multi-stress responses and virulence of two entomopathogenic fungi. Fungal Genetics and Biology 2013, 54:42-51. 10.1016/j.fgb.2013.02.008.
96. Love B.E., Bonner-Stewart J., Forrest L.A. An efficient synthesis of oosporein. Tetrahedron Letters 2009, 50:5050-5052. 10.1016/J.Tetlet.2009.06.103.
97. Luo X.D., Keyhani N.O., Yu X.D., He Z.J., Luo Z.B., Pei Y., et al. The MAP kinase Bbslt2 controls growth, conidiation, cell wall integrity, and virulence in the insect pathogenic fungus Beauveria bassiana. Fungal Genetics and Biology 2012, 49:544-555. 10.1016/J.Fgb.2012.05.002.
98. Luo Z., Li Y., Mousa J., Bruner S., Zhang Y., Pei Y., et al. Bbmsn2 acts as a pH-dependent negative regulator of secondary metabolite production in the entomopathogenic fungus Beauveria bassiana. Environmental Microbiology 2014, 10.1111/1462-2920.12542.
99. Luo Z., Qin Y., Pei Y., Keyhani N.O. Ablation of the creA regulator results in amino acid toxicity, temperature sensitivity, pleiotropic effects on cellular development and loss of virulence in the filamentous fungus Beauveria bassiana. Environmental Microbiology 2014, 16:1122-1136. 10.1111/1462-2920.12352.
100. Ma J.C., Zhou Q., Zhou Y.H., Liao X.G., Zhang Y.J., Jin D., et al. The size and ratio of homologous sequence to non-homologous sequence in gene disruption cassette influences the gene targeting efficiency in Beauveria bassiana. Applied Microbiology and Biotechnology 2009, 82:891-898. 10.1007/s00253-008-1844-0.
101. Mantilla J.G., Galeano N.F., Gaitan A.L., Cristancho M.A., Keyhani N.O., Gongora C.E. Transcriptome analysis of the entomopathogenic fungus Beauveria bassiana grown on cuticular extracts of the coffee berry borer (Hypothenemus hampei). Microbiology 2012, 158:1826-1842. 10.1099/mic.0.051664-0.
102. Mao B.Z., Huang C., Yang G.M., Chen Y.Z., Chen S.Y. Separation and determination of the bioactivity of oosporein from Chaetomium cupreum. African Journal of Biotechnology 2010, 9:5955-5961.
103. Maurer P., Rejasse A., Capy P., Langin T., Riba G. Isolation of the transposable element hupfer from the entomopathogenic fungus Beauveria bassiana by insertion mutagenesis of the nitrate reductase structural gene. Molecular & General Genetics 1997, 256:195-202.
104. Mazet I., Hung S.Y., Boucias D.G. Detection of toxic metabolites in the hemolymph of Beauveria bassiana infected Spodoptera exigua larvae. Experientia 1994, 50:142-147.
105. Meyling N.V., Eilenberg J. Isolation and characterisation of Beauveria bassiana isolates from phylloplanes of hedgerow vegetation. Mycological Research 2006, 110:188-195. 10.1016/j.mycres.2005.09.008.
106. Meyling N.V., Hajek A.E. Principles from community and metapopulation ecology: application to fungal entomopathogens. BioControl 2010, 55:39-54.
107. Molnar I., Gibson D.M., Krasnoff S.B. Secondary metabolites from entomopathogenic hypocrealean fungi. Natural Product Reports 2010, 27:1241-1275.
108. Nagaoka T., Nakata K., Kouno K., Ando T. Antifungal activity of oosporein from an antagonistic fungus against Phytophthora infestans. Zeitschrift fuer Naturforschung, C 2004, 59:302-304.
109. Ni M., Yu J.H. A novel regulator couples sporogenesis and trehalose biogenesis in Aspergillus nidulans. PLoS One 2007, 2:e970. 10.1371/journal.pone.0000970.
110. Oh J., Kong W.S., Sung G.H. Complete mitochondrial genome of the entomopathogenic fungus Beauveria pseudobassiana (Ascomycota, Cordycipitaceae). Mitochondrial DNA 2015, 26:777-778. 10.3109/19401736.2013.855747.
111. Ortiz-Urquiza A., Keyhani N.O. Action on the surface: entomopathogenic fungi versus the insect cuticle. Insects 2013, 4:357-374.
112. Ortiz-Urquiza A., Keyhani N.O. Stress response signaling and virulence: insights from entomopathogenic fungi. Current Genetics 2014, 10.1007/s00294-014-0439-9.
113. Ortiz-Urquiza A., Keyhani N.O., Quesada-Moraga E. Culture conditions affect virulence and production of insect toxic proteins in the entomopathogenic fungus Metarhizium anisopliae. Biocontrol Science and Technology 2013, 23:1199-1212. 10.1080/09583157.2013.822474.
114. Ortiz-Urquiza A., Luo Z., Keyhani N.O. Improving mycoinsecticides for insect biological control. Applied Microbiology and Biotechnology 2015, 99:1057-1068. 10.1007/s00253-014-6270-x.
115. Panek A.D., Bernardes E., Ortiz C.H., Baker S., Mattoon J.R. Biochemical genetics of trehalose metabolism in Saccharomyces-Cerevisiae. Anais da Academia Brasileira de Ciencias 1981, 53:165-172.
116. Pedrini N., Ortiz-Urquiza A., Huarte-Bonnet C., Fan Y., Juarez M.P., Keyhani N.O. Tenebrionid secretions and a fungal benzoquinone oxidoreductase form competing components of an arms race between a host and pathogen. Proceedings of the National Academy of Sciences of the United States of America 2015, 112:E3651-E3660. 10.1073/pnas.1504552112.
117. Pedrini N., Ortiz-Urquiza A., Huarte-Bonnet C., Zhang S., Keyhani N.O. Targeting of insect epicuticular lipids by the entomopathogenic fungus Beauveria bassiana: hydrocarbon oxidation within the context of a host-pathogen interaction. Frontiers in Microbiology 2013, 4:24. 10.3389/fmicb.2013.00024.
118. Pedrini N., Zhang S.Z., Juarez M.P., Keyhani N.O. Molecular characterization and expression analysis of a suite of cytochrome P450 enzymes implicated in insect hydrocarbon degradation in the entomopathogenic fungus Beauveria bassiana. Microbiology-Sgm 2010, 156:2549-2557. 10.1099/Mic.0.039735-0.
119. Pegram R., Wyatt R.D., Smith T.L. Oosporein-toxicosis in the turkey poult. Avian Diseases 1981, 26:47-59.
120. Pendland J.C., Hung S.Y., Boucias D.G. Evasion of host defense by in vivo-produced protoplast-like cells of the insect mycopathogen Beauveria bassiana. Journal of Bacteriology 1993, 175:5962-5969.
121. Pfeifer T.A., Hegedus D.D., Khachatourians G.G. The mitochondrial genome of the entomopathogenic fungus Beauveria bassiana: analysis of the ribosomal RNA region. Canadian Journal of Microbiology 1993, 39:25-31.
122. Pfeifer T.A., Khachatourians G.G. Isolation and characterization of DNA from the entomopathogen Beauveria bassiana. Experimental Mycology 1989, 13:392-402. 10.1016/0147-5975(89)90035-2.
123. Pfeifer T.A., Khachatourians G.G. Beauveria bassiana protoplast regeneration and transformation using electroporation. Applied Microbiology and Biotechnology 1992, 38:376-381.
124. Pomerening J.R., Ubersax J.A., Ferrell J.E. Rapid cycling and precocious termination of G1 phase in cells expressing CDK1AF. Molecular Biology of the Cell 2008, 19:3426-3441. 10.1091/mbc.E08-02-0172.
125. Qazi S.S., Khachatourians G.G. Addition of exogenous carbon and nitrogen sources to aphid exuviae modulates synthesis of proteases and chitinase by germinating conidia of Beauveria bassiana. Archives of Microbiology 2008, 189:589-596.
126. Qin Y., Ortiz-Urquiza A., Keyhani N.O. A putative methyltransferase, mtrA, contributes to development, spore viability, protein secretion, and virulence in the entomopathogenic fungus Beauveria bassiana. Microbiology 2014, 10.1099/mic.0.078469-0.
127. Qiu L., Wang J.J., Chu Z.J., Ying S.H., Feng M.G. Phytochrome controls conidiation in response to red/far-red light and daylight length and regulates multistress tolerance in Beauveria bassiana. Environmental Microbiology 2014, 16:2316-2328. 10.1111/1462-2920.12486.
128. Qiu L., Wang J.J., Ying S.H., Feng M.G. Wee1 and Cdc25 control morphogenesis, virulence and multistress tolerance of Beauveria bassiana by balancing cell cycle-required cyclin-dependent kinase 1 activity. Environmental Microbiology 2015, 17:1119-1133. 10.1111/1462-2920.12530.
129. Rao Y.K., Lu S.C., Liu B.L., Tzeng Y.M. Enhanced production of an extracellular protease from Beauveria bassiana by optimization of cultivation processes. Biochemical Engineering Journal 2006, 28:57-66. 10.1016/j.bej.2005.09.005.
130. Rehner S.A., Buckley E. A Beauveria phylogeny inferred from nuclear ITS and EF1-alpha sequences: evidence for cryptic diversification and links to Cordyceps teleomorphs. Mycologia 2005, 97:84-98.
131. Rehner S.A., Minnis A.M., Sung G.H., Luangsa-ard J.J., Devotto L., Humber R.A. Phylogeny and systematics of the anamorphic, entomopathogenic genus Beauveria. Mycologia 2011, 103:1055-1073. 10.3852/10-302.
132. Roy H.E., Steinkraus D.C., Eilenberg J., Hajek A.E., Pell J.K. Bizarre interactions and endgames: entomopathogenic fungi and their arthropod hosts. Annual Review of Entomology 2006, 51:331-357.
133. Safavi S.A. Successive subculturing alters spore-bound Pr1 activity, germination and virulence of the entomopathogenic fungus, Beauveria bassiana. Biocontrol Science and Technology 2011, 21:883-890. 10.1080/09583157.2011.588317.
134. Samsinakova A., Kalalova S. The influence of a single-spore isolate and repeated subculturing on the pathogenicity of conidia of the entomophagous fungus Beauveria bassiana. Journal of Invertebrate Pathology 1983, 42:156-161.
135. Shapiro-Ilan D.I., Fuxa J.R., Lacey L.A., Onstad D.W., Kaya H.K. Definitions of pathogenicity and virulence in invertebrate pathology. Journal of Invertebrate Pathology 2005, 88:1-7. 10.1016/j.jip.2004.10.003.
136. Shimizu S., Tsuchitani Y., Matsumoto T. Production of an extracellular protease by Beauveria bassiana in the hemolymph of the silkworm, Bombyx mori. Letters in Applied Microbiology 1993, 16:291-294. 10.1111/j.1472-765X.1993.tb00360.x.
137. Smith R.J., Grula E.A. Chitinase is an inducible enzyme in Beauveria bassiana. Journal of Invertebrate Pathology 1983, 42:319-326.
138. Solomon P.S., Waters O.D.C., Jorgens C.I., Lowe R.G.T., Rechberger J., Trengove R.D., et al. Mannitol is required for asexual sporulation in the wheat pathogen Stagonospora nodorum (glume blotch). Biochemical Journal 2006, 399:231-239.
139. Song T.T., Feng M.G. In vivo passages of heterologous Beauveria bassiana isolates improve conidial surface properties and pathogenicity to Nilaparvata lugens (Homoptera: Delphacidae). Journal of Invertebrate Pathology 2011, 106:211-216. 10.1016/j.jip.2010.09.022.
140. Song T.T., Zhao J., Ying S.H., Feng M.G. Differential contributions of five ABC transporters to mutidrug resistance, antioxidion and virulence of Beauveria bassiana, an entomopathogenic fungus. PLoS One 2013, 8:e62179. 10.1371/journal.pone.0062179.
141. St Leger R.J., Cooper R.M., Charnley A.K. Distribution of chymoelastases and trypsin-like enzymes in five species of entomopathogenic deuteromycetes. Archives of Biochemistry and Biophysics 1987, 258:123-131.
142. St Leger R.J., Joshi L., Bidochka M.J., Rizzo N.W., Roberts D.W. Characterization and ultrastructural localization of chitinases from Metarhizium anisopliae, M-flavoviride, and Beauveria bassiana during fungal invasion of host (Manduca sexta) cuticle. Applied and Environmental Microbiology 1996, 62:907-912.
143. St Leger R., Joshi L., Bidochka M.J., Roberts D.W. Construction of an improved mycoinsecticide overexpressing a toxic protease. Proceedings of the National Academy of Sciences of the United States of America 1996, 93:6349-6354.
144. St Leger R.J., Joshi L., Roberts D.W. Adaptation of proteases and carbohydrates of saprophytic, phytopathogenic and entomopathogenic fungi to the requirements of their ecological niches. Microbiology 1997, 143(Pt 6):1983-1992.
145. Strasser H., Abendstein D., Stuppner H., Butt T.M. Monitoring the distribution of secondary metabolites produced by the entomogenous fungus Beauveria brongniartii with particular reference to oosporein. Mycological Research 2000, 104:1227-1233.
146. Tartar A., Boucias D.G. A pilot-scale expressed sequence tag analysis of Beauveria bassiana gene expression reveals a tripeptidyl peptidase that is differentially expressed in vivo. Mycopathologia 2004, 158:201-209.
147. Terry B.J., Liu W.C., Cianci C.W., Proszynski E., Fernandes P., Bush K., et al. Inhibition of herpes-simplex virus type-1 DNA-polymerase by the natural product oosporein. Journal of Antibiotics 1992, 45:286-288.
148. Thomas S.R., Elkinson J.S. Pathogenicity and virulence. Journal of Invertebrate Pathology 2004, 85:146-151. 10.1016/j.jip.2004.01.006.
149. Urtz B.E., Rice W.C. Purification and characterization of a novel extracellular protease from Beauveria bassiana. Mycological Research 2000, 104:180-186. 10.1017/S0953756299001215.
150. Vega F.E., Goettel M.S., Blackwell M., Chandler D., Jackson M.A., Keller S., et al. Fungal entomopathogens: new insights on their ecology. Fungal Ecology 2009, 2:149-159.
151. Vega F.E., Posada F., Aime M.C., Pava-Ripoll M., Infante F., Rehner S.A. Entomopathogenic fungal endophytes. Biological Control 2008, 46:72-82.
152. Viaud M., Couteaudier Y., Levis C., Riba G. Genome organization in Beauveria bassiana: electrophoretic karyotype, gene mapping, and telomeric fingerprints. Fungal Genetics and Biology 1996, 20:175-183.
153. Wanchoo A., Lewis M.W., Keyhani N.O. Lectin mapping reveals stage-specific display of surface carbohydrates in in vitro and haemolymph-derived cells of the entomopathogenic fungus Beauveria bassiana. Microbiology-Sgm 2009, 155:3121-3133.
154. Wang C.S., Leger R.J.S. The Metarhizium anisopliae perilipin homolog MPL1 regulates lipid metabolism, appressorial turgor pressure, and virulence. Journal of Biological Chemistry 2007, 282:21110-21115.
155. Wang C.S., St Leger R.J. The MAD1 adhesin of Metarhizium anisopliae links adhesion with blastospore production and virulence to insects, and the MAD2 adhesin enables attachment to plants. Eukaryotic Cell 2007, 6:808-816.
156. Wang J., Liu J., Hu Y., Ying S.H., Feng M.G. Cytokinesis-required Cdc14 is a signaling hub of asexual development and multi-stress tolerance in Beauveria bassiana. Scientific Reports-UK 2013, 3:3086. 10.1038/Srep03086.
157. Wang J., Zhou G., Ying S.H., Feng M.G. P-type calcium ATPase functions as a core regulator of Beauveria bassiana growth, conidiation and responses to multiple stressful stimuli through cross-talk with signalling networks. Environmental Microbiology 2013, 15:967-979. 10.1111/1462-2920.12044.
158. Wang J., Zhou G., Ying S.H., Feng M.G. Adenylate cyclase orthologues in two filamentous entomopathogens contribute differentially to growth, conidiation, pathogenicity, and multistress responses. Fungal Biology 2014, 118:422-431. 10.1016/j.funbio.2014.03.001.
159. Wang J.J., Qiu L., Cai Q., Ying S.H., Feng M.G. Three alpha-1,2-mannosyltransferases contribute differentially to conidiation, cell wall integrity, multistress tolerance and virulence of Beauveria bassiana. Fungal Genetics and Biology 2014, 70:1-10. 10.1016/j.fgb.2014.06.010.
160. Wang J.J., Qiu L., Cai Q., Ying S.H., Feng M.G. Transcriptional control of fungal cell cycle and cellular events by Fkh2, a forkhead transcription factor in an insect pathogen. Scientific Reports-UK 2015, 5:10108. 10.1038/srep10108.
161. Wang J.J., Qiu L., Chu Z.J., Ying S.H., Feng M.G. The connection of protein O-mannosyltransferase family to the biocontrol potential of Beauveria bassiana, a fungal entomopathogen. Glycobiology 2014, 24:638-648. 10.1093/glycob/cwu028.
162. Wang X.X., He P.H., Feng M.G., Ying S.H. BbSNF1 contributes to cell differentiation, extracellular acidification, and virulence in Beauveria bassiana, a filamentous entomopathogenic fungus. Applied Microbiology and Biotechnology 2014, 98:8657-8673. 10.1007/s00253-014-5907-0.
163. Wang X.X., Ji X.P., Li J.X., Keyhani N.O., Feng M.G., Ying S.H. The putative alpha-glucoside transporter gene BbAGT1 contributed to carbohydrate utilization, growth, conidiation and virulence of filamentous entomopathogenic fungi Beauveria bassiana. Research in Microbiology 2013, 10.1016/j.resmic.2013.02.008.
164. Wang Z.L., Li F., Li C., Feng M.G. Bbssk1, a response regulator required for conidiation, multi-stress tolerance, and virulence of Beauveria bassiana. Applied Microbiology and Biotechnology 2014, 98:5607-5618. 10.1007/s00253-014-5644-4.
165. Wang Z.L., Lu J.D., Feng M.G. Primary roles of two dehydrogenases in the mannitol metabolism and multi-stress tolerance of entomopathogenic fungus Beauveria bassiana. Environmental Microbiology 2012, 14:2139-2150. 10.1111/j.1462-2920.2011.02654.x.
166. Wang Z.L., Zhang L.B., Ying S.H., Feng M.G. Catalases play differentiated roles in the adaptation of a fungal entomopathogen to environmental stresses. Environmental Microbiology 2013, 15:409-418. 10.1111/j.1462-2920.2012.02848.x.
167. Wraight S.P., Ramos M.E., Avery P.B., Jaronski S.T., Vandenberg J.D. Comparative virulence of Beauveria bassiana isolates against lepidopteran pests of vegetable crops. Journal of Invertebrate Pathology 2010, 103:186-199. 10.1016/j.jip.2010.01.001.
168. Wu J., Ridgway H., Carpenter M., Glare T. Efficient transformation of Beauveria bassiana by Agrobacterium tumefaciens-mediated insertional mutagenesis. Australasian Plant Pathology 2008, 37:537-542.
169. Wu J., Ridgway H.J., Carpenter M.A., Glare T.R. Identification of novel genes associated with conidiation in Beauveria bassiana with suppression subtractive hybridization. Mycologia 2008, 100:20-30.
170. Xiao G., Ying S.H., Zheng P., Wang Z.L., Zhang S., Xie X.Q., et al. Genomic perspectives on the evolution of fungal entomopathogenicity in Beauveria bassiana. Scientific Reports 2012, 2:483. 10.1038/srep00483.
171. Xie X.Q., Guan Y., Ying S.H., Feng M.G. Differentiated functions of Ras1 and Ras2 proteins in regulating the germination, growth, conidiation, multi-stress tolerance and virulence of Beauveria bassiana. Environmental Microbiology 2013, 15:447-462. 10.1111/j.1462-2920.2012.02871.x.
172. Xie X.Q., Li F., Ying S.H., Feng M.G. Additive contributions of two manganese-cored superoxide dismutases (MnSODs) to antioxidation, UV tolerance and virulence of Beauveria bassiana. PLoS One 2012, 7:e30298. 10.1371/journal.pone.0030298.
173. Xie X.Q., Wang J., Huang B.F., Ying S.H., Feng M.G. A new manganese superoxide dismutase identified from Beauveria bassiana enhances virulence and stress tolerance when overexpressed in the fungal pathogen. Applied Microbiology and Biotechnology 2010, 86:1543-1553. 10.1007/S00253-010-2437-2.
174. Xu Y., Orozco R., Wijeratne E.M.K., Gunatilaka A.A.L., Stock S.P., Molnar I. Biosynthesis of the cyclooligomer depsipeptide beauvericin, a virulence factor of the entomopathogenic fungus Beauveria bassiana. Chemistry & Biology 2008, 15:898-907.
175. Xu Y., Zhan J., Wijeratne E.M.K., Burns A.M., Gunatilaka A.A.L., Molnar I. Cytotoxic and antihaptotactic beauvericin analogues from precursor-directed biosynthesis with the insect pathogen Beauveria bassiana ATCC 7159. Journal of Natural Products 2007, 70:1467-1471.
176. Xu Y.Q., Rozco R., Wijeratne E.M.K., Espinosa-Artiles P., Gunatilaka A.A.L., Stock S.P., et al. Biosynthesis of the cyclooligomer depsipeptide bassianolide, an insecticidal virulence factor of Beauveria bassiana. Fungal Genetics and Biology 2009, 46:353-364.
177. Xu Y.Q., Wijeratne E.M.K., Espinosa-Artiles P., Gunatilaka A.A.L., Molnar I. Combinatorial mutasynthesis of scrambled beauvericins, cyclooligomer depsipeptide cell migration inhibitors from Beauveria bassiana. Chembiochem 2009, 10:345-354.
178. Ying S.H., Feng M.G. A conidial protein (CP15) of Beauveria bassiana contributes to the conidial tolerance of the entomopathogenic fungus to thermal and oxidative stresses. Applied Microbiology and Biotechnology 2011, 90:1711-1720. 10.1007/s00253-011-3205-7.
179. Ying S.H., Feng M.G., Keyhani N.O. A carbon responsive G-protein coupled receptor modulates broad developmental and genetic networks in the entomopathogenic fungus, Beauveria bassiana. Environmental Microbiology 2013, 15:2902-2921. 10.1111/1462-2920.12169.
180. Ying S.H., Feng M.G., Keyhani N.O. Use of uridine auxotrophy (ura3) for markerless transformation of the mycoinsecticide Beauveria bassiana. Applied Microbiology and Biotechnology 2013, 97:3017-3025. 10.1007/s00253-012-4426-0.
181. Ying S.H., Ji X.P., Wang X.X., Feng M.G., Keyhani N.O. The transcriptional co-activator multiprotein bridging factor 1 from the fungal insect pathogen, Beauveria bassiana, mediates regulation of hyphal morphogenesis, stress tolerance and virulence. Environmental Microbiology 2014, 16:1879-1897. 10.1111/1462-2920.12450.
182. Zhang L., Wang J., Xie X.Q., Keyhani N.O., Feng M.G., Ying S.H. The autophagy gene BbATG5, involved in the formation of the autophagosome, contributes to cell differentiation and growth but is dispensable for pathogenesis in the entomopathogenic fungus Beauveria bassiana. Microbiology 2013, 159:243-252. 10.1099/mic.0.062646-0.
183. Zhang L.B., Tang L., Ying S.H., Feng M.G. Subcellular localization of six thioredoxins and their antioxidant activity and contributions to biological control potential in Beauveria bassiana. Fungal Genetics and Biology 2015, 76:1-9. 10.1016/j.fgb.2015.01.008.
184. Zhang S., Fan Y., Xia Y.X., Keyhani N.O. Sulfonylurea resistance as a new selectable marker for the entomopathogenic fungus Beauveria bassiana. Applied Microbiology and Biotechnology 2010, 87:1151-1156. 10.1007/s00253-010-2636-x.
185. Zhang S., Widemann E., Bernard G., Lesot A., Pinot F., Pedrini N., et al. CYP52X1, representing new cytochrome P450 subfamily, displays fatty acid hydroxylase activity and contributes to virulence and growth on insect cuticular substrates in entomopathogenic fungus Beauveria bassiana. Journal of Biological Chemistry 2012, 287:13477-13486. 10.1074/jbc.M111.338947.
186. Zhang S.Z., Xia Y.X., Keyhani N.O. Contribution of the gas1 gene of the entomopathogenic fungus Beauveria bassiana, encoding a putative glycosylphosphatidylinositol-anchored beta-1,3-glucanosyltransferase, to conidial thermotolerance and virulence. Applied and Environmental Microbiology 2011, 77:2676-2684.
187. Zhang S.Z., Xia Y.X., Kim B., Keyhani N.O. Two hydrophobins are involved in fungal spore coat rodlet layer assembly and each play distinct roles in surface interactions, development and pathogenesis in the entomopathogenic fungus, Beauveria bassiana. Molecular Microbiology 2011, 80:811-826.
188. Zhang Y.J., Feng M.G., Fan Y.H., Luo Z.B., Yang X.Y., Wu D., et al. A cuticle-degrading protease (CDEP-1) of Beauveria bassiana enhances virulence. Biocontrol Science and Technology 2008, 18:551-563. 10.1080/09583150802082239.
189. Zhang Y.J., Zhang J.Q., Jiang X.D., Wang G.J., Luo Z.B., Fan Y.H., et al. Requirement of a mitogen activated protein kinase for appressorium formation and penetration of insect cuticle by the entomopathogenic fungus Beauveria bassiana. Applied and Environmental Microbiology 2010, 76:2262-2270. 10.1128/Aem.02246-09.
190. Zhang Y.J., Zhao J.H., Fang W.G., Zhang J.Q., Luo Z.B., Zhang M., et al. Mitogen-activated protein kinase hog1 in the entomopathogenic fungus beauveria bassiana regulates environmental stress responses and virulence to insects. Applied and Environmental Microbiology 2009, 75:3787-3795. 10.1128/Aem.01913-08.
191. Zibaee A., Bandani A.R. Purification and characterization of the cuticle-degrading protease produced by the entomopathogenic fungus, Beauveria bassiana in the presence of Sunn pest, Eurygaster integriceps (Hemiptera: Scutelleridae) cuticle. Biocontrol Science and Technology 2009, 19:797-808. pii:913279411. 10.1080/09583150903132172.
192. Zimmermann G. The Galleria bait method for detection of entomopathogenic fungi in soil. Journal of Applied Entomology-Zeitschrift Fur Angewandte Entomologie 1986, 102:213-215.