-
1
-
-
84866364390
-
The anatomical and cellular basis of immune surveillance in the central nervous system
-
Ransohoff RM, Engelhardt B: The anatomical and cellular basis of immune surveillance in the central nervous system. Nat Rev Immunol 2012; 12: 623-635.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 623-635
-
-
Ransohoff, R.M.1
Engelhardt, B.2
-
3
-
-
84887309465
-
Tumor-associated edema in brain cancer patients: Pathogenesis and management
-
Roth P, Regli L, Tonder M, Weller M: Tumor-associated edema in brain cancer patients: Pathogenesis and management. Expert Rev Anticancer Ther 2013; 13: 1319-1325.
-
(2013)
Expert Rev Anticancer Ther
, vol.13
, pp. 1319-1325
-
-
Roth, P.1
Regli, L.2
Tonder, M.3
Weller, M.4
-
4
-
-
84907024513
-
Pathogenesis of multiple sclerosis: Insights from molecular and metabolic imaging
-
Ciccarelli O, Barkhof F, Bodini B, et al.: Pathogenesis of multiple sclerosis: Insights from molecular and metabolic imaging. Lancet Neurol 2014; 13: 807-822.
-
(2014)
Lancet Neurol
, vol.13
, pp. 807-822
-
-
Ciccarelli, O.1
Barkhof, F.2
Bodini, B.3
-
5
-
-
84936871460
-
Structural and functional features of central nervous system lymphatic vessels
-
Louveau A, Smirnov I, Keyes TJ, et al.: Structural and functional features of central nervous system lymphatic vessels. Nature 2015; 523: 337-341.
-
(2015)
Nature
, vol.523
, pp. 337-341
-
-
Louveau, A.1
Smirnov, I.2
Keyes, T.J.3
-
6
-
-
84959020187
-
Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid
-
Schlager C, Korner H, Krueger M, et al.: Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid. Nature 2016; 530: 349-353.
-
(2016)
Nature
, vol.530
, pp. 349-353
-
-
Schlager, C.1
Korner, H.2
Krueger, M.3
-
7
-
-
84954429886
-
Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases
-
Berghoff AS, Fuchs E, Ricken G, et al.: Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases. Oncoimmunology 2016; 5:e1057388.
-
(2016)
Oncoimmunology
, vol.5
, pp. e1057388
-
-
Berghoff, A.S.1
Fuchs, E.2
Ricken, G.3
-
8
-
-
0036140228
-
Safety and efficacy of high-dose interleukin-2 therapy in patients with brain metastases
-
Guirguis LM, Yang JC, White DE, et al.: Safety and efficacy of high-dose interleukin-2 therapy in patients with brain metastases. J Immunother 2002; 25: 82-87.
-
(2002)
J Immunother
, vol.25
, pp. 82-87
-
-
Guirguis, L.M.1
Yang, J.C.2
White, D.E.3
-
9
-
-
84894090550
-
High-dose interleukin-2 (HD IL-2) therapy should be considered for treatment of patients with melanoma brain metastases
-
Chu MB, Fesler MJ, Armbrecht ES, et al.: High-dose interleukin-2 (HD IL-2) therapy should be considered for treatment of patients with melanoma brain metastases. Chemother Res Pract 2013; 2013: 726925.
-
(2013)
Chemother Res Pract
, vol.2013
, pp. 726925
-
-
Chu, M.B.1
Fesler, M.J.2
Armbrecht, E.S.3
-
11
-
-
84925596863
-
Transforming growth factor-beta pathway activity in glioblastoma
-
Frei K, Gramatzki D, Tritschler I, et al.: Transforming growth factor-beta pathway activity in glioblastoma. Oncotarget 2015; 6: 5963-5977.
-
(2015)
Oncotarget
, vol.6
, pp. 5963-5977
-
-
Frei, K.1
Gramatzki, D.2
Tritschler, I.3
-
12
-
-
77955100047
-
GDF-15 contributes to proliferation and immune escape of malignant gliomas
-
Roth P, Junker M, Tritschler I, et al.: GDF-15 contributes to proliferation and immune escape of malignant gliomas. Clin Cancer Res 2010; 16: 3851-3859.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3851-3859
-
-
Roth, P.1
Junker, M.2
Tritschler, I.3
-
13
-
-
84907546541
-
MicroRNA-mediated down-regulation of NKG2D ligands contributes to glioma immune escape
-
Codo P, Weller M, Meister G, et al.: MicroRNA-mediated down-regulation of NKG2D ligands contributes to glioma immune escape. Oncotarget 2014; 5: 7651-7662.
-
(2014)
Oncotarget
, vol.5
, pp. 7651-7662
-
-
Codo, P.1
Weller, M.2
Meister, G.3
-
14
-
-
34248529706
-
Malignant glioma cells counteract antitumor immune responses through expression of lectin-like transcript-1
-
Roth P, Mittelbronn M, Wick W, et al.: Malignant glioma cells counteract antitumor immune responses through expression of lectin-like transcript-1. Cancer Res 2007; 67: 3540-3544.
-
(2007)
Cancer Res
, vol.67
, pp. 3540-3544
-
-
Roth, P.1
Mittelbronn, M.2
Wick, W.3
-
15
-
-
0028807156
-
Human gliomaderived interleukin-10 inhibits antitumor immune responses in vitro
-
discussion 1166-1167
-
Hishii M, Nitta T, Ishida H, et al.: Human gliomaderived interleukin-10 inhibits antitumor immune responses in vitro. Neurosurgery 1995; 37: 1160-1166;discussion 1166-1167.
-
(1995)
Neurosurgery
, vol.37
, pp. 1160-1166
-
-
Hishii, M.1
Nitta, T.2
Ishida, H.3
-
16
-
-
0022598888
-
Prostaglandin E2 as an immunomodulating factor released in vitro by human glioma cells
-
Lauro GM, Di Lorenzo N, Grossi M, et al.: Prostaglandin E2 as an immunomodulating factor released in vitro by human glioma cells. Acta Neuropathol 1986; 69: 278-282.
-
(1986)
Acta Neuropathol
, vol.69
, pp. 278-282
-
-
Lauro, G.M.1
Di Lorenzo, N.2
Grossi, M.3
-
17
-
-
34248172651
-
CD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo
-
Grauer OM, Nierkens S, Bennink E, et al.: CD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo. Int J Cancer 2007; 121: 95-105.
-
(2007)
Int J Cancer
, vol.121
, pp. 95-105
-
-
Grauer, O.M.1
Nierkens, S.2
Bennink, E.3
-
18
-
-
84961288435
-
First-in-human dose study of the novel transforming growth factor-beta receptor i kinase inhibitor LY2157299 monohydrate in patients with advanced cancer and glioma
-
Rodon J, Carducci MA, Sepulveda-Sanchez JM, et al.: First-in-human dose study of the novel transforming growth factor-beta receptor I kinase inhibitor LY2157299 monohydrate in patients with advanced cancer and glioma. Clin Cancer Res 2015; 21: 553-560.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 553-560
-
-
Rodon, J.1
Carducci, M.A.2
Sepulveda-Sanchez, J.M.3
-
19
-
-
84982131467
-
A phase II randomized study of galunisertib monotherapy or galunisertib plus lomustine compared with lomustine monotherapy in patients with recurrent glioblastoma
-
Epub ahead of print
-
Brandes AA, Carpentier AF, Kesari S, et al.: A phase II randomized study of galunisertib monotherapy or galunisertib plus lomustine compared with lomustine monotherapy in patients with recurrent glioblastoma. Neuro Oncol 2016;[Epub ahead of print].
-
(2016)
Neuro Oncol
-
-
Brandes, A.A.1
Carpentier, A.F.2
Kesari, S.3
-
20
-
-
84868220730
-
Tryptophan catabolism in cancer: Beyond IDO and tryptophan depletion
-
Platten M, Wick W, Van den Eynde BJ: Tryptophan catabolism in cancer: Beyond IDO and tryptophan depletion. Cancer Res 2012; 72: 5435-5440.
-
(2012)
Cancer Res
, vol.72
, pp. 5435-5440
-
-
Platten, M.1
Wick, W.2
Van Den Eynde, B.J.3
-
21
-
-
84869232447
-
IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival
-
Wainwright DA, Balyasnikova IV, Chang AL, et al.: IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival. Clin Cancer Res 2012; 18: 6110-6121.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 6110-6121
-
-
Wainwright, D.A.1
Balyasnikova, I.V.2
Chang, A.L.3
-
22
-
-
84937517015
-
The role of IDO in brain tumor immunotherapy
-
Zhai L, Lauing KL, Chang AL, et al.: The role of IDO in brain tumor immunotherapy. J Neurooncol 2015; 123: 395-403.
-
(2015)
J Neurooncol
, vol.123
, pp. 395-403
-
-
Zhai, L.1
Lauing, K.L.2
Chang, A.L.3
-
23
-
-
84918768887
-
A phase I/II study of the combination of indoximod and temozolomide for adult patients with temozolomiderefractory primary malignant brain tumors
-
Zakharia Y, Johnson TS, Colman H, Vahanian NN: A phase I/II study of the combination of indoximod and temozolomide for adult patients with temozolomiderefractory primary malignant brain tumors. J Clin Oncol 2014; 32: 5s.
-
(2014)
J Clin Oncol
, vol.32
, pp. 5s
-
-
Zakharia, Y.1
Johnson, T.S.2
Colman, H.3
Vahanian, N.N.4
-
24
-
-
84941615057
-
Cytotoxic T lymphocyte antigen-4 and immune checkpoint blockade
-
Buchbinder E, Hodi FS: Cytotoxic T lymphocyte antigen-4 and immune checkpoint blockade. J Clin Invest 2015; 125: 3377-3383.
-
(2015)
J Clin Invest
, vol.125
, pp. 3377-3383
-
-
Buchbinder, E.1
Hodi, F.S.2
-
25
-
-
84941025149
-
Prospects of immune checkpoint modulators in the treatment of glioblastoma
-
Preusser M, Lim M, Hafler DA, et al.: Prospects of immune checkpoint modulators in the treatment of glioblastoma. Nat Rev Neurol 2015; 11: 504-514.
-
(2015)
Nat Rev Neurol
, vol.11
, pp. 504-514
-
-
Preusser, M.1
Lim, M.2
Hafler, D.A.3
-
26
-
-
84904207094
-
Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model
-
Belcaid Z, Phallen JA, Zeng J, et al.: Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model. PloS One 2014; 9:e101764.
-
(2014)
PloS One
, vol.9
, pp. e101764
-
-
Belcaid, Z.1
Phallen, J.A.2
Zeng, J.3
-
27
-
-
84962032646
-
Glioblastoma eradication following immune checkpoint blockade in an orthotopic, immunocompetent model
-
Reardon DA, Gokhale PC, Klein SR, et al.: Glioblastoma eradication following immune checkpoint blockade in an orthotopic, immunocompetent model. Cancer Immunol Res 2016; 4: 124-135.
-
(2016)
Cancer Immunol Res
, vol.4
, pp. 124-135
-
-
Reardon, D.A.1
Gokhale, P.C.2
Klein, S.R.3
-
28
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, et al.: Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010; 363: 711-723.
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
29
-
-
84860446616
-
Ipilimumab in patients with melanoma and brain metastases: An open-label, phase 2 trial
-
Margolin K, Ernstoff MS, Hamid O, et al.: Ipilimumab in patients with melanoma and brain metastases: An open-label, phase 2 trial. Lancet Oncol 2012; 13: 459-465.
-
(2012)
Lancet Oncol
, vol.13
, pp. 459-465
-
-
Margolin, K.1
Ernstoff, M.S.2
Hamid, O.3
-
30
-
-
84865567547
-
Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): An open-label, single-arm phase 2 trial
-
Di Giacomo AM, Ascierto PA, Pilla L, et al.: Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): An open-label, single-arm phase 2 trial. Lancet Oncol 2012; 13: 879-886.
-
(2012)
Lancet Oncol
, vol.13
, pp. 879-886
-
-
Di Giacomo, A.M.1
Ascierto, P.A.2
Pilla, L.3
-
31
-
-
84890230046
-
Ipilimumab in melanoma patients with brain metastasis: A retro-spective multicentre evaluation of thirtyeight patients
-
Konstantinou MP, Dutriaux C, Gaudy-Marqueste C, et al.: Ipilimumab in melanoma patients with brain metastasis: A retro-spective multicentre evaluation of thirtyeight patients. Acta Derm Venereol 2014; 94: 45-49.
-
(2014)
Acta Derm Venereol
, vol.94
, pp. 45-49
-
-
Konstantinou, M.P.1
Dutriaux, C.2
Gaudy-Marqueste, C.3
-
32
-
-
84904216679
-
Ipilimumab and radiation therapy for melanoma brain metastases
-
Silk AW, Bassetti MF, West BT, et al.: Ipilimumab and radiation therapy for melanoma brain metastases. Cancer Med 2013; 2: 899-906.
-
(2013)
Cancer Med
, vol.2
, pp. 899-906
-
-
Silk, A.W.1
Bassetti, M.F.2
West, B.T.3
-
33
-
-
85005893688
-
Survival of melanoma patients with brain metastases treated with ipilimumab and stereotactic radiosurgery
-
Tazi K, Hathaway A, Chiuzan C, Shirai K: Survival of melanoma patients with brain metastases treated with ipilimumab and stereotactic radiosurgery. Cancer Med 2015; 4: 1-6.
-
(2015)
Cancer Med
, vol.4
, pp. 1-6
-
-
Tazi, K.1
Hathaway, A.2
Chiuzan, C.3
Shirai, K.4
-
34
-
-
84928938600
-
Stereotactic radiosurgery for melanoma brain metastases in patients receiving ipilimumab: Safety profile and efficacy of combined treatment
-
Kiess AP, Wolchok JD, Barker CA, et al.: Stereotactic radiosurgery for melanoma brain metastases in patients receiving ipilimumab: Safety profile and efficacy of combined treatment. Int J Radiat Oncol Biol Phys 2015; 92: 368-375.
-
(2015)
Int J Radiat Oncol Biol Phys
, vol.92
, pp. 368-375
-
-
Kiess, A.P.1
Wolchok, J.D.2
Barker, C.A.3
-
35
-
-
84925266488
-
Tumourinfiltrating lymphocytes and expression of programmed death ligand 1 (PD-L1) in melanoma brain metastases
-
Berghoff AS, Ricken G, Widhalm G, et al.: Tumourinfiltrating lymphocytes and expression of programmed death ligand 1 (PD-L1) in melanoma brain metastases. Histopathology 2015; 66: 289-299.
-
(2015)
Histopathology
, vol.66
, pp. 289-299
-
-
Berghoff, A.S.1
Ricken, G.2
Widhalm, G.3
-
36
-
-
84950980021
-
Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases
-
Harter PN, Bernatz S, Scholz A, et al.: Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases. Oncotarget 2015; 6: 40836-40849.
-
(2015)
Oncotarget
, vol.6
, pp. 40836-40849
-
-
Harter, P.N.1
Bernatz, S.2
Scholz, A.3
-
37
-
-
84925222119
-
Nivolumab in previously untreated melanoma without BRAF mutation
-
Robert C, Long GV, Brady B, et al.: Nivolumab in previously untreated melanoma without BRAF mutation. N Engl J Med 2015; 372: 320-330.
-
(2015)
N Engl J Med
, vol.372
, pp. 320-330
-
-
Robert, C.1
Long, G.V.2
Brady, B.3
-
38
-
-
84908354848
-
Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: A randomised dose-comparison cohort of a phase 1 trial
-
Robert C, Ribas A, Wolchok JD, et al.: Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: A randomised dose-comparison cohort of a phase 1 trial. Lancet 2014; 384: 1109-1117.
-
(2014)
Lancet
, vol.384
, pp. 1109-1117
-
-
Robert, C.1
Ribas, A.2
Wolchok, J.D.3
-
39
-
-
84959928939
-
Successful treatment with an anti-PD-1 antibody for progressing brain metastases in renal cell cancer
-
Rothermundt C, Hader C, Gillessen S: Successful treatment with an anti-PD-1 antibody for progressing brain metastases in renal cell cancer. Ann Oncol 2016; 27: 544-545.
-
(2016)
Ann Oncol
, vol.27
, pp. 544-545
-
-
Rothermundt, C.1
Hader, C.2
Gillessen, S.3
-
40
-
-
84960396403
-
Safety and activity of pembrolizumab in melanoma patients with untreated brain metastases
-
abstr 9009
-
Kluger HM, Goldberg SB, Sznol M, et al.: Safety and activity of pembrolizumab in melanoma patients with untreated brain metastases. J Clin Oncol 2015; 33 (suppl, abstr 9009).
-
(2015)
J Clin Oncol
, vol.33
-
-
Kluger, H.M.1
Goldberg, S.B.2
Sznol, M.3
-
41
-
-
84924901863
-
Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (checkmate 063): A phase 2, single-arm trial
-
Rizvi NA, Mazieres J, Planchard D, et al.: Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (checkmate 063): A phase 2, single-arm trial. Lancet Oncol 2015; 16: 257-265.
-
(2015)
Lancet Oncol
, vol.16
, pp. 257-265
-
-
Rizvi, N.A.1
Mazieres, J.2
Planchard, D.3
-
42
-
-
84942138571
-
Activity and safety of pembrolizumab in patients with metastatic non-small cell lung cancer with untreated brain metastases
-
abstr 8035
-
Goldberg SB, Gettinger SN, Mahajan A, et al.: Activity and safety of pembrolizumab in patients with metastatic non-small cell lung cancer with untreated brain metastases. J Clin Oncol 2015; 33 (suppl; abstr 8035).
-
(2015)
J Clin Oncol
, vol.33
-
-
Goldberg, S.B.1
Gettinger, S.N.2
Mahajan, A.3
-
43
-
-
84959919017
-
Clinical outcomes of melanoma brain metastases treated with stereotactic radiation and anti-PD-1 therapy
-
Ahmed KA, Stallworth DG, Kim Y, et al.: Clinical outcomes of melanoma brain metastases treated with stereotactic radiation and anti-PD-1 therapy. Ann Oncol 2016; 27: 434-441.
-
(2016)
Ann Oncol
, vol.27
, pp. 434-441
-
-
Ahmed, K.A.1
Stallworth, D.G.2
Kim, Y.3
-
44
-
-
84943241524
-
Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma
-
Berghoff AS, Kiesel B, Widhalm G, et al.: Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma. Neuro Oncol 2015; 17: 1064-1075.
-
(2015)
Neuro Oncol
, vol.17
, pp. 1064-1075
-
-
Berghoff, A.S.1
Kiesel, B.2
Widhalm, G.3
-
45
-
-
84960407098
-
PD-L1 expression and prognostic impact in glioblastoma
-
Nduom EK, Wei J, Yaghi NK, et al.: PD-L1 expression and prognostic impact in glioblastoma. Neuro Oncol 2016; 18: 195-205.
-
(2016)
Neuro Oncol
, vol.18
, pp. 195-205
-
-
Nduom, E.K.1
Wei, J.2
Yaghi, N.K.3
-
46
-
-
84947509509
-
Preliminary safety and activity of nivolumab and its combination with ipilimumab in recurrent glioblastoma (GBM): Checkmate-143
-
abstr 3010
-
Sampson JH, Vlahovic G, Sahebjam S, et al.: Preliminary safety and activity of nivolumab and its combination with ipilimumab in recurrent glioblastoma (GBM): Checkmate-143. J Clin Oncol 2015; 33 (suppl; abstr 3010).
-
(2015)
J Clin Oncol
, vol.33
-
-
Sampson, J.H.1
Vlahovic, G.2
Sahebjam, S.3
-
48
-
-
84879066269
-
An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma
-
Reardon DA, Wucherpfennig KW, Freeman G, et al.: An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma. Expert Rev Vaccines 2013; 12: 597-615.
-
(2013)
Expert Rev Vaccines
, vol.12
, pp. 597-615
-
-
Reardon, D.A.1
Wucherpfennig, K.W.2
Freeman, G.3
-
49
-
-
79955784386
-
Greater chemotherapy-induced lymphopenia enhances tumorspecific immune responses that eliminate EGFRvIIIexpressing tumor cells in patients with glioblastoma
-
Sampson JH, Aldape KD, Archer GE, et al.: Greater chemotherapy-induced lymphopenia enhances tumorspecific immune responses that eliminate EGFRvIIIexpressing tumor cells in patients with glioblastoma. Neuro Oncol 2011; 13: 324-333.
-
(2011)
Neuro Oncol
, vol.13
, pp. 324-333
-
-
Sampson, J.H.1
Aldape, K.D.2
Archer, G.E.3
-
50
-
-
78149254368
-
Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma
-
Sampson JH, Heimberger AB, Archer GE, et al.: Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma. J Clin Oncol 2010; 28: 4722-4729.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4722-4729
-
-
Sampson, J.H.1
Heimberger, A.B.2
Archer, G.E.3
-
51
-
-
84934981297
-
A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: The ACT III study
-
Schuster J, Lai RK, Recht LD, et al.: A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: The ACT III study. Neuro Oncol 2015; 17: 854-861.
-
(2015)
Neuro Oncol
, vol.17
, pp. 854-861
-
-
Schuster, J.1
Lai, R.K.2
Recht, L.D.3
-
52
-
-
84947485465
-
ReACT: Overall survival from a randomized phase II study of rindopepimut (CDX-110) plus bevacizumab in relapsed glioblastoma
-
abstr 2009
-
Reardon DA, Schuster J, Tran DD, Fink KL: ReACT: Overall survival from a randomized phase II study of rindopepimut (CDX-110) plus bevacizumab in relapsed glioblastoma. J Clin Oncol 2015; 33(suppl; abstr 2009).
-
(2015)
J Clin Oncol
, vol.33
-
-
Reardon, D.A.1
Schuster, J.2
Tran, D.D.3
Fink, K.L.4
-
53
-
-
34047131797
-
Vascular endothelial growth factor and immunosuppression in cancer: Current knowledge and potential for new therapy
-
Johnson BF, Clay TM, Hobeika AC, et al.: Vascular endothelial growth factor and immunosuppression in cancer: Current knowledge and potential for new therapy. Expert Opin Biol Ther 2007; 7: 449-460.
-
(2007)
Expert Opin Biol Ther
, vol.7
, pp. 449-460
-
-
Johnson, B.F.1
Clay, T.M.2
Hobeika, A.C.3
-
54
-
-
84922713971
-
VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors
-
Voron T, Colussi O, Marcheteau E, et al.: VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors. J Exp Med 2015; 212: 139-148.
-
(2015)
J Exp Med
, vol.212
, pp. 139-148
-
-
Voron, T.1
Colussi, O.2
Marcheteau, E.3
-
55
-
-
84930416369
-
Wilms tumor 1 peptide vaccination combined with temozolomide against newly diagnosed glioblastoma: Safety and impact on immunological response
-
Hashimoto N, Tsuboi A, Kagawa N, et al.: Wilms tumor 1 peptide vaccination combined with temozolomide against newly diagnosed glioblastoma: Safety and impact on immunological response. Cancer Immunol Immunother 2015; 64: 707-716.
-
(2015)
Cancer Immunol Immunother
, vol.64
, pp. 707-716
-
-
Hashimoto, N.1
Tsuboi, A.2
Kagawa, N.3
-
56
-
-
84906557615
-
A vaccine targeting mutant IDH1 induces antitumour immunity
-
Schumacher T, Bunse L, Pusch S, et al.: A vaccine targeting mutant IDH1 induces antitumour immunity. Nature 2014; 512: 324-327.
-
(2014)
Nature
, vol.512
, pp. 324-327
-
-
Schumacher, T.1
Bunse, L.2
Pusch, S.3
-
57
-
-
84920969943
-
Induction of robust type-I CD8+ T-cell responses in WHO grade 2 low-grade glioma patients receiving peptidebased vaccines in combination with poly-ICLC
-
Okada H, Butterfield LH, Hamilton RL, et al.: Induction of robust type-I CD8+ T-cell responses in WHO grade 2 low-grade glioma patients receiving peptidebased vaccines in combination with poly-ICLC. Clin Cancer Res 2015; 21: 286-294.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 286-294
-
-
Okada, H.1
Butterfield, L.H.2
Hamilton, R.L.3
-
58
-
-
84905817445
-
Antigenspecific immune responses and clinical outcome after vaccination with glioma-associated antigen peptides and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in children with newly diagnosed malignant brainstem and nonbrainstem gliomas
-
Pollack IF, Jakacki RI, Butterfield LH, et al.: Antigenspecific immune responses and clinical outcome after vaccination with glioma-associated antigen peptides and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in children with newly diagnosed malignant brainstem and nonbrainstem gliomas. J Clin Oncol 2014; 32: 2050-2058.
-
(2014)
J Clin Oncol
, vol.32
, pp. 2050-2058
-
-
Pollack, I.F.1
Jakacki, R.I.2
Butterfield, L.H.3
-
59
-
-
84872498982
-
Phase i trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma
-
Phuphanich S, Wheeler CJ, Rudnick JD, et al.: Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma. Cancer Immunol Immunother 2013; 62: 125-135.
-
(2013)
Cancer Immunol Immunother
, vol.62
, pp. 125-135
-
-
Phuphanich, S.1
Wheeler, C.J.2
Rudnick, J.D.3
-
60
-
-
84916606024
-
A randomized, double-blind, placebo-controlled phase 2 trial of dendritic cell (DC) vaccination with ICT-107 in newly diagnosed glioblastoma (GBM) patients
-
suppl; abstr 2005
-
Wen PY, Reardon DA, Phuphanich S, Aitken R: A randomized, double-blind, placebo-controlled phase 2 trial of dendritic cell (DC) vaccination with ICT-107 in newly diagnosed glioblastoma (GBM) patients. J Clin Oncol 2014; 32: 5s(suppl; abstr 2005).
-
(2014)
J Clin Oncol
, vol.32
, pp. 5s
-
-
Wen, P.Y.1
Reardon, D.A.2
Phuphanich, S.3
Aitken, R.4
-
61
-
-
84947496189
-
Immunotherapy for glioblastoma: Concepts and challenges
-
Weiss T, Weller M, Roth P: Immunotherapy for glioblastoma: Concepts and challenges. Curr Opin Neurol 2015; 28: 639-646.
-
(2015)
Curr Opin Neurol
, vol.28
, pp. 639-646
-
-
Weiss, T.1
Weller, M.2
Roth, P.3
-
62
-
-
84925045090
-
Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients
-
Mitchell DA, Batich KA, Gunn MD, et al.: Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients. Nature 2015; 519: 366-369.
-
(2015)
Nature
, vol.519
, pp. 366-369
-
-
Mitchell, D.A.1
Batich, K.A.2
Gunn, M.D.3
-
63
-
-
84979268324
-
Chimeric antigen receptors modified T-cells for cancer therapy
-
pii:djv439
-
Dai H, Wang Y, Lu X, Han W: Chimeric antigen receptors modified T-cells for cancer therapy. J Natl Cancer Inst 2016; 108:pii:djv439.
-
(2016)
J Natl Cancer Inst
, vol.108
-
-
Dai, H.1
Wang, Y.2
Lu, X.3
Han, W.4
-
64
-
-
84923078274
-
Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma
-
Johnson LA, Scholler J, Ohkuri T, et al.: Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma. Sci Transl Med 2015; 7: 275ra222.
-
(2015)
Sci Transl Med
, vol.7
, pp. 275ra222
-
-
Johnson, L.A.1
Scholler, J.2
Ohkuri, T.3
-
65
-
-
84942908170
-
Bioactivity and safety of IL13Ralpha2-redirected chimeric antigen receptor CD8+ T cells in patients with recurrent glioblastoma
-
Brown CE, Badie B, Barish ME, et al.: Bioactivity and safety of IL13Ralpha2-redirected chimeric antigen receptor CD8+ T cells in patients with recurrent glioblastoma. Clin Cancer Res 2015; 21: 4062-4072.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 4062-4072
-
-
Brown, C.E.1
Badie, B.2
Barish, M.E.3
-
66
-
-
84908555818
-
A phase i study evaluating ABT-414 in combination with temozolomide (TMZ) for subjects with recurrent or unresectable glioblastoma (GBM)
-
Gan HK, Fichtel L, Lassman AB, et al.: A phase I study evaluating ABT-414 in combination with temozolomide (TMZ) for subjects with recurrent or unresectable glioblastoma (GBM). J Clin Oncol 2014; 32: 5s.
-
(2014)
J Clin Oncol
, vol.32
, pp. 5s
-
-
Gan, H.K.1
Fichtel, L.2
Lassman, A.B.3
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