Novel predictors of sepsis outperform the american burn association sepsis criteria in the burn intensive care unit patient

Journal of Burn Care and Research

Volumn 34, Issue 1, 2013, Pages 31-43

  Mann Salinas, Elizabeth A ^a,b   Baun, Mara M ^a   Meininger, Janet C ^a   Murray, Clinton K ^c   Aden, James K ^b   Wolf, Steven E ^d   Wade, Charles E ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON   (United States)

^b US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

^c SAN ANTONIO MILITARY MEDICAL CENTER   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AMERICAN BURN ASSOCIATION CRITERIA; AREA UNDER THE CURVE; ARTICLE; BLOOD CULTURE; BURN; BURN PATIENT; CASE CONTROL STUDY; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; RATING SCALE; RETROSPECTIVE STUDY; SEPSIS;

ACID-BASE EQUILIBRIUM; ADULT; ANALYSIS OF VARIANCE; AREA UNDER CURVE; BIOLOGICAL MARKERS; BLOOD GLUCOSE; BLOOD PRESSURE; BODY TEMPERATURE; BURN UNITS; BURNS; CASE-CONTROL STUDIES; FEMALE; HEART RATE; HUMANS; INTENSIVE CARE UNITS; LOGISTIC MODELS; MALE; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; RISK FACTORS; SEPSIS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 84873081387     PISSN: 1559047X     EISSN: 15590488     Source Type: Journal    
DOI: 10.1097/BCR.0b013e31826450b5     Document Type: Article

References (32)

1. Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992;101:1644-55.
2. Fitzwater J, Purdue GF, Hunt JL, O'Keefe GE. The risk factors and time course of sepsis and organ dysfunction after burn trauma. J Trauma 2003;54:959-66.
3. Cumming J, Purdue GF, Hunt JL, O'Keefe GE. Objective estimates of the incidence and consequences of multiple organ dysfunction and sepsis after burn trauma. J Trauma 2001;50:510-5.
4. D'Avignon LC, Hogan BK, Murray CK, et al. Contribution of bacterial and viral infections to attributable mortality in patients with severe burns: an autopsy series. Burns 2010;36:773-9.
5. Sharma BR, Harish D, Singh VP, Bangar S. Septicemia as a cause of death in burns: an autopsy study. Burns 2006;32:545-9.
6. Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International sepsis definitions conference. Crit Care Med 2003;31:1250-6.
7. Greenhalgh DG, Saffle JR, Holmes JH 4th, et al.; American Burn Association Consensus Conference on Burn Sepsis and Infection Group. American Burn Association consensus conference to define sepsis and infection in burns. J Burn Care Res 2007;28:776-90.
8. Vincent JL, Sakr Y, Sprung CL, et al.; Sepsis Occurrence in Acutely Ill Patients Investigators. Sepsis in European intensive care units: results of the SOAP study. Crit Care Med 2006;34:344-53.
9. Murray CK, Hoffmaster RM, Schmit DR, et al. Evaluation of white blood cell count, neutrophil percentage, and elevated temperature as predictors of bloodstream infection in burn patients. Arch Surg 2007;142:639-42.
10. Hogan BK, Wolf SE, Hospenthal DR, et al. Correlation of American Burn Association Sepsis Criteria with the presence of bacteremia in burned patients admitted to the intensive care unit. J Burn Care Res 2012;33:371-8.
11. Lodise TP Jr, Patel N, Kwa A, et al. Predictors of 30-day mortality among patients with Pseudomonas aeruginosa bloodstream infections: impact of delayed appropriate antibiotic selection. Antimicrob Agents Chemother 2007;51: 3510-5.
12. Custer J, Spaeder M, James F. Critical care decision support. Contemporary Critical Care 2008;6:1-9.
13. Kleinpell RM, Graves BT, Ackerman MH. Incidence, pathogenesis, and management of sepsis: an overview. AACN Adv Crit Care 2006;17:385-93.
14. Wolf SE, Kauvar DS, Wade CE, et al. Comparison between civilian burns and combat burns from Operation Iraqi Freedom and Operation Enduring Freedom. Ann Surg 2006;243:786-92; discussion 792-5.
15. Hosmerven-D, Lemeshow S. Applied logistic regression. 2nd ed. New York: John Wiley & Sons, Inc; 2000.
16. Keen EF 3rd, Robinson BJ, Hospenthal DR, et al. Incidence and bacteriology of burn infections at a military burn center. Burns 2010;36:461-8.
17. Albrecht MC, Albrecht MA, Griffith ME, et al. Impact of Acinetobacter infection on the mortality of burn patients. J Am Coll Surg 2006;203:546-50.
18. Andersen SK, Gjedsted J, Christiansen C, Tønnesen E. The roles of insulin and hyperglycemia in sepsis pathogenesis. J Leukoc Biol 2004;75:413-21.
19. Van Cromphaut SJ, Vanhorebeek I, Van den Berghe G. Glucose metabolism and insulin resistance in sepsis. Curr Pharm Des 2008;14:1887-99.
20. Shangraw RE, Jahoor F, Miyoshi H, et al. Differentiation between septic and postburn insulin resistance. Metab Clin Exp 1989;38:983-9.
21. Wilmore DW, Mason AD Jr, Pruitt BA Jr. Insulin response to glucose in hypermetabolic burn patients. Ann Surg 1976;183:314-20.
22. Mann EA, Wood GL, Wade CE. Use of procalcitonin for the detection of sepsis in the critically ill burn patient: a systematic review of the literature. Burns 2011;37:549-58.
23. Jensen JU, Hein L, Lundgren B, et al.; Procalcitonin And Survival Study (PASS) Group. Procalcitonin-guided interventions against infections to increase early appropriate antibiotics and improve survival in the intensive care unit: a randomized trial. Crit Care Med 2011;39:2048-58.
24. Keen A, Knoblock L, Edelman L, Saffle J. Effective limitation of blood culture use in the burn unit. J Burn Care Rehabil 2002;23:183-9.
25. Nobre V, Sarasin FP, Pugin J. Prompt antibiotic administration and goal-directed hemodynamic support in patients with severe sepsis and septic shock. Curr Opin Crit Care 2007;13:586-91.
26. Garg AX, Adhikari NK, McDonald H, et al. Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: a systematic review. JAMA 2005;293:1223-38.
27. Kawamoto K, Houlihan CA, Balas EA, Lobach DF. Improving clinical practice using clinical decision support systems: a systematic review of trials to identify features critical to success. BMJ 2005;330:765.
28. Sawyer AM, Deal EN, Labelle AJ, et al. Implementation of a real-time computerized sepsis alert in nonintensive care unit patients. Crit Care Med 2011;39:469-73.
29. McKinley BA, Moore LJ, Sucher JF, et al. Computer protocol facilitates evidence-based care of sepsis in the surgical intensive care unit. J Trauma 2011;70:1153-66; discussion 1166-57.
30. Moore LJ, Jones SL, Kreiner LA, et al. Validation of a screening tool for the early identification of sepsis. J Trauma 2009;66:1539-46; discussion 1537-46.
31. Vincent JL, Martinez EO, Silva E. Evolving concepts in sepsis definitions. Crit Care Clin 2009;25:665-75, vii.
32. Rubulotta F, Marshall JC, Ramsay G, Nelson D, Levy M, Williams M. Predisposition, insult/infection, response, and organ dysfunction: A new model for staging severe sepsis. Crit Care Med 2009;37:1329-35.