Inhibition of T cell receptor signaling by cholesterol sulfate, a naturally occurring derivative of membrane cholesterol

Nature Immunology

Volumn 17, Issue 7, 2016, Pages 844-850

  Wang, Feng ^a   Beck García, Katharina ^b   Zorzin, Carina ^b   Schamel, Wolfgang W A ^b   Davis, Mark M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CHOLESTEROL; CHOLESTEROL SULFATE; ITAM PROTEIN; MEMBRANE PROTEIN; POLYMER; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG; CHOLESTEROL ESTER; LYMPHOCYTE ANTIGEN RECEPTOR; SULFOTRANSFERASE; SULT2B1B PROTEIN, MOUSE;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL MATURATION; CELL MEMBRANE; CONTROLLED STUDY; GROWTH INHIBITORY CONCENTRATION; INJECTION; MOLECULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE ACTIVATION; THYMOCYTE; THYMUS; ANALOGS AND DERIVATIVES; ANIMAL; ANTIGEN MEDIATED CLONAL SELECTION; AUTOIMMUNITY; C57BL MOUSE; CELL CULTURE; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; AUTOIMMUNITY; CELL MEMBRANE; CELLS, CULTURED; CHOLESTEROL; CHOLESTEROL ESTERS; CLONAL SELECTION, ANTIGEN-MEDIATED; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHORYLATION; PROTEIN MULTIMERIZATION; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SIGNAL TRANSDUCTION; SULFOTRANSFERASES; T-LYMPHOCYTES; THYMUS GLAND;

EID: 84969902310     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3462     Document Type: Article

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