Circulating Neutrophil Extracellular Trap Levels in Well-Controlled Type 2 Diabetes and Pathway Involved in Their Formation Induced by High-Dose Glucose

Pathobiology

Volumn 83, Issue 5, 2016, Pages 243-251

  Miyoshi, Arina ^a   Yamada, Mai ^a   Shida, Haruki ^a   Nakazawa, Daigo ^a   Kusunoki, Yoshihiro ^a   Nakamura, Akinobu ^a   Miyoshi, Hideaki ^a   Tomaru, Utano ^b   Atsumi, Tatsuya ^a   Ishizu, Akihiro ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Aldose reductase inhibitor; Microvascular complications; Myeloperoxidase DNA complex; Neutrophil extracellular trap; Polyol pathway; Type 2 diabetes

Indexed keywords

ANTIDIABETIC AGENT; BIOLOGICAL MARKER; DNA; GLUCOSE; MYELOPEROXIDASE; RANIRESTAT; PEROXIDASE; POLYMER; POLYOL; PYRAZINE DERIVATIVE; PYRROLE DERIVATIVE; QUINAZOLINE DERIVATIVE; SOTRASTAURIN; SPIRO COMPOUND;

ARTICLE; BLOOD SAMPLING; CHEMICAL PARAMETERS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATIONAL STUDY; DIABETIC PATIENT; DRUG INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR TRAP; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; IN VIVO STUDY; LABORATORY TEST; NEUTROPHIL; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RISK FACTOR; SERUM; SIGNAL TRANSDUCTION; ADULT; AGED; BLOOD; CASE CONTROL STUDY; COMPLICATION; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHY; DOSE RESPONSE; DRUG EFFECTS; GENETICS; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; TIME FACTOR; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BIOMARKERS; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR TRAPS; GLUCOSE; HUMANS; HYPOGLYCEMIC AGENTS; MIDDLE AGED; NEUTROPHILS; PEROXIDASE; POLYMERS; PYRAZINES; PYRROLES; QUINAZOLINES; RISK FACTORS; SPIRO COMPOUNDS; TIME FACTORS;

EID: 84969837188     PISSN: 10152008     EISSN: 14230291     Source Type: Journal    
DOI: 10.1159/000444881     Document Type: Article

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