Cognitive deficits and brain myo-Inositol are early biomarkers of epileptogenesis in a rat model of epilepsy

Neurobiology of Disease

Volumn 93, Issue , 2016, Pages 146-155

  Pascente, Rosaria ^a   Frigerio, Federica ^a   Rizzi, Massimo ^a   Porcu, Luca ^a   Boido, Marina ^b   Davids, Joe ^c   Zaben, Malik ^c   Tolomeo, Daniele ^a   Filibian, Marta ^a,d   Gray, William P ^c   Vezzani, Annamaria ^a   Ravizza, Teresa ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF PAVIA   (Italy)

Author keywords

Astrocytes; Biomarker; Comorbidities; Epileptogenesis; Hippocampus; Imaging; Learning and memory; Status epilepticus

Indexed keywords

INOSITOL; PILOCARPINE; PROTEIN S100B;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BEHAVIOR DISORDER; BRAIN INJURY; CELL ACTIVATION; CELL LOSS; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MODEL; ELECTROENCEPHALOGRAPHY; EPILEPSY; EPILEPTIC STATE; EPILEPTOGENESIS; HIPPOCAMPUS; HISTOPATHOLOGY; LEARNING; LEARNING DISORDER; MALE; MEMORY DISORDER; MORRIS WATER MAZE TEST; NERVE CELL; NERVE CELL DIFFERENTIATION; NONHUMAN; PREDICTION; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; RISK ASSESSMENT; SPATIAL LEARNING; ANIMAL; BRAIN; COMPLICATION; METABOLISM; NERVOUS SYSTEM DEVELOPMENT; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; SPRAGUE DAWLEY RAT;

ANIMALS; ASTROCYTES; BEHAVIOR, ANIMAL; BRAIN; COGNITIVE DYSFUNCTION; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; MALE; NEUROGENESIS; NEURONS; RATS, SPRAGUE-DAWLEY; STATUS EPILEPTICUS;

EID: 84969625568     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2016.05.001     Document Type: Article

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