Enhanced Re-Endothelialization of Decellularized Rat Lungs

Tissue Engineering - Part C: Methods

Volumn 22, Issue 5, 2016, Pages 439-450

  Stabler, Collin T ^a   Caires, Luiz C ^a,b   Mondrinos, Mark J ^a   Marcinkiewicz, Cezary ^a   Lazarovici, Philip ^a   Wolfson, Marla R ^c   Lelkes, Peter I ^a  

^a Temple University   (United States)

^b FEDERAL UNIVERSITY OF JUIZ DE FORA   (Brazil)

^c TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; ENDOTHELIAL CELLS; GLYCOPROTEINS; PULMONARY DISEASES; RATS; SCAFFOLDS (BIOLOGY);

CELLULAR DISTRIBUTIONS; ENDOTHELIAL BARRIERS; ENDOTHELIALIZATION; EXTRACELLULAR MATRICES; MICROVASCULAR ENDOTHELIAL CELLS; PERFUSION CULTURES; PULMONARY VASCULATURE; VASCULAR FUNCTIONS;

BIOLOGICAL ORGANS;

COLLAGEN TYPE 1; COLLAGEN TYPE 4; FIBRONECTIN; VERY LATE ACTIVATION ANTIGEN 2; VERY LATE ACTIVATION ANTIGEN 5;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL DIAMETER; BODY POSTURE; CAPILLARY ENDOTHELIAL CELL; CELL ADHESION; CELL COUNTING; CELL MATURATION; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DECELLULARIZATION; EXTRACELLULAR MATRIX; HISTOGENESIS; HISTOLOGY; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; LUNG BLOOD VESSEL; LUNG PARENCHYMA; MALE; NONHUMAN; PRIORITY JOURNAL; PROCEDURES CONCERNING CELLS; PULMONARY ARTERY; RAT; REENDOTHELIALIZATION; SCANNING ELECTRON MICROSCOPY; STANDING; SUPINE POSITION; ANIMAL; CELL CULTURE; CHEMISTRY; CYTOLOGY; ENDOTHELIUM CELL; LUNG; PERFUSION; PROCEDURES; SPRAGUE DAWLEY RAT; TISSUE ENGINEERING; TISSUE SCAFFOLD; VASCULARIZATION;

ANIMALS; CELLS, CULTURED; ENDOTHELIAL CELLS; EXTRACELLULAR MATRIX; LUNG; MALE; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84969262224     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2016.0012     Document Type: Article

References (36)

1. Valapour, M., Paulson, K., Smith, J.M., Hertz, M.I., Skeans, M.A., Heubner, B.M., Edwards, L.B., Snyder, J.J., Israni, A.K., and Kasiske, B.L. OPTN/SRTR 2011 Annual Data Report: lung. Am J Transplant 13 Suppl 1, 149, 2013.
2. Scarritt, M.E., Pashos, N.C., and Bunnell, B.A. A review of cellularization strategies for tissue engineering of whole organs. Front Bioeng Biotechnol 3, 43, 2015.
3. Bae, H., Puranik, A.S., Gauvin, R., Edalat, F., Carrillo-Conde, B., Peppas, N.A., and Khademhosseini, A. BuilDing vascular networks. Sci Transl Med 4, 160ps23, 2012.
4. Stabler, C.T., Lecht, S., Mondrinos, M.J., Goulart, E., Lazarovici, P., and Lelkes, P.I. Revascularization of decellularized lung scaffolds: principles and progress. Am J Physiol Lung Cell Mol Physiol 309, 1273, 2015.
5. Ren, X., Moser, P.T., Gilpin, S.E., Okamoto, T., Wu, T., Tapias, L.F., Mercier, F.E., Xiong, L., Ghawi, R., Scadden, D.T., Mathisen, D.J., and Ott, H.C. Engineering pulmonary vasculature in decellularized rat and human lungs. Nat Biotechnol 33, 1097, 2015.
6. Song, J.J., Kim, S.S., Liu, Z., Madsen, J.C., Mathisen, D.J., Vacanti, J.P., and Ott, H.C. Enhanced in vivo function of bioartificial lungs in rats. Ann Thorac Sur 92, 998, 2011.
7. Petersen, T.H., Calle, E.A., Zhao, L., Lee, E.J., Gui, L., Raredon, M.B., Gavrilov, K., Yi, T., Zhuang, Z.W., Breuer, C., Herzog, E., and Niklason, L.E. Tissue-engineered lungs for in vivo implantation. Science 329, 538, 2010.
8. Ott, H.C., Clippinger, B., Conrad, C., Schuetz, C., Pomerantseva, I., Ikonomou, L., Kotton, D., and Vacanti, J.P. Regeneration and orthotopic transplantation of a bioartificial lung. Nat Med 16, 927, 2010.
9. Richter, T., Bergmann, R., Pietzsch, J., Kozle, I., Hofheinz, F., Schiller, E., Ragaller, M., and van den Hoff, J. Effects of posture on regional pulmonary blood flow in rats as measured by PET. J Appl Physiol 108, 422, 2010.
10. Bauters, C., Marotte, F., Hamon, M., Oliviero, P., Farhadian, F., Robert, V., Samuel, J.L., and Rappaport, L. Accumulation of fetal fibronectin mRNAs after balloon denudation of rabbit arteries. Circulation 92, 904, 1995.
11. Seebach, J., Dieterich, P., Luo, F., Schillers, H., Vestweber, D., Oberleithner, H., Galla, H.J., and Schnittler, H.J. Endothelial barrier function under laminar fluid shear stress. Lab Invest 80, 1819, 2000.
12. Bonvillain, R.W., Danchuk, S., Sullivan, D.E., Betancourt, A.M., Semon, J.A., Eagle, M.E., Mayeux, J.P., Gregory, A.N., Wang, G., Townley, I.K., Borg, Z.D., Weiss, D.J., and Bunnell, B.A. A nonhuman primate model of lung regeneration: detergent-mediated decellularization and initial in vitro recellularization with mesenchymal stem cells. Tissue Eng Part A 18, 2437, 2012.
13. Price, A.P., England, K.A., Matson, A.M., Blazar, B.R., and Panoskaltsis-Mortari, A. Development of a decellularized lung bioreactor system for bioengineering the lung: the matrix reloaded. Tissue Eng Part A 16, 2581, 2010.
14. Daly, A.B., Wallis, J.M., Borg, Z.D., Bonvillain, R.W., Deng, B., Ballif, B.A., Jaworski, D.M., Allen, G.B., and Weiss, D.J. Initial binDing and recellularization of decellularized mouse lung scaffolds with bone marrowderived mesenchymal stromal cells. Tissue Eng Part A 18, 1, 2012.
15. Bur, S., Bachofen, H., Gehr, P., and Weibel, E.R. Lung fixation by airway instillation: effects on capillary hematocrit. Exp Lung Res 9, 57, 1985.
16. Lecht, S., Stabler, C.T., Rylander, A.L., Chiaverelli, R., Schulman, E.S., Marcinkiewicz, C., and Lelkes, P.I. Enhanced reseeDing of decellularized rodent lungs with mouse embryonic stem cells. Biomaterials 35, 3252, 2014.
17. Senel Ayaz, H.G., Perets, A., Ayaz, H., Gilroy, K.D., Govindaraj, M., Brookstein, D., and Lelkes, P.I. Textiletemplated electrospun anisotropic scaffolds for regenerative cardiac tissue engineering. Biomaterials 35, 8540, 2014.
18. Stabler, C.T., Lecht, S., Barakat, M., Junior, L.C., Rylander, A.L., Chiaverelli, R., Schulman, E.S., Marcinkiewicz, C., and Lelkes, P.I. Enhanced reseeDing of decellularized rodent lung airway and vasculature. Presented at the Biomedical Engineering Society Annual Meeting, San Antonio, TX, Abstract No. 2500, 2014.
19. Marcinkiewicz, C. Applications of snake venom components to modulate integrin activities in cell-matrix interactions. Int J Biochem Cell Biol 45, 1974, 2013.
20. Stabler, C.T., Junior, L.C., Marcinkiewicz, C., and Lelkes, P.I. Integrin specific re-endothelialization within decellularized lungs. Presented at the Tissue Engineering and Regenerative Medicine International Society World Congress, Boston, MA, Abstract No. 1973.
21. Girard, E.D., Jensen, T.J., Vadasz, S.D., Blanchette, A.E., Zhang, F., Moncada, C., Weiss, D.J., and Finck, C.M. Automated procedure for biomimetic de-cellularized lung scaffold supporting alveolar epithelial transdifferentiation. Biomaterials 34, 10043, 2013.
22. Dintenfass, L. Blood Microrheology: Viscosity Factors in Blood Flow, Ischaemia, and Thrombosis; An Introduction to Molecular and Clinical Haemorheology. New York, NY: Appleton-Century-Crofts, 1971.
23. Liu, Z., Xi, R., Zhang, Z., Li, W., Liu, Y., Jin, F., and Wang, X. 4-Hydroxyphenylacetic acid attenuated inflammation and edema via suppressing HIF-1alpha in seawater aspiration-induced lung injury in rats. Int J Mol Sci 15, 12861, 2014.
24. Nagao, R.J., Ouyang, Y., Keller, R., Lee, C., Suggs, L.J., and Schmidt, C.E. Preservation of capillary-beds in rat lung tissue using optimized chemical decellularization. J Mater Chem B Mater Biol Med 1, 4801, 2013.
25. Maghsoudlou, P., Georgiades, F., Tyraskis, A., Totonelli, G., Loukogeorgakis, S.P., Orlando, G., Shangaris, P., Lange, P., Delalande, J.M., Burns, A.J., Cenedese, A., Sebire, N.J., Turmaine, M., Guest, B.N., Alcorn, J.F., Atala, A., Birchall, M.A., Elliott, M.J., Eaton, S., Pierro, A., Gilbert, T.W., and De Coppi, P. Preservation of microarchitecture and angiogenic potential in a pulmonary acellular matrix obtained using intermittent intra-tracheal flow of detergent enzymatic treatment. Biomaterials 34, 6638, 2013.
26. Price, A.P., Godin, L.M., Domek, A., Cotter, T., D'Cunha, J., Taylor, D.A., and Panoskaltsis-Mortari, A. Automated decellularization of intact, human-sized lungs for tissue engineering. Tissue Eng Part C Methods 21, 94, 2014.
27. Hill, R.C., Calle, E.A., Dzieciatkowska, M., Niklason, L.E., and Hansen, K.C. Quantification of extracellular matrix proteins from a rat lung scaffold to provide a molecular readout for tissue engineering. Mol Cell Proteomics 14, 961, 2015.
28. Fernandez, L.G., Le Cras, T.D., Ruiz, M., Glover, D.K., Kron, I.L., and Laubach, V.E. Differential vascular growth in postpneumonectomy compensatory lung growth. J Thoracic Cardiovasc Surg 133, 309, 2007.
29. Wallis, J.M., Borg, Z.D., Daly, A.B., Deng, B., Ballif, B.A., Allen, G.B., Jaworski, D.M., and Weiss, D.J. Comparative assessment of detergent-based protocols for mouse lung decellularization and re-cellularization. Tissue Eng Part C Methods 18, 420, 2012.
30. Wagenseil, J.E., and Mecham, R.P. Vascular extracellular matrix and arterial mechanics. Physiol Rev 89, 957, 2009.
31. Walter, D.H., Rittig, K., Bahlmann, F.H., Kirchmair, R., Silver, M., Murayama, T., Nishimura, H., Losordo, D.W., Asahara, T., and Isner, J.M. Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells. Circulation 105, 3017, 2002.
32. Inoue, T., Croce, K., Morooka, T., Sakuma, M., Node, K., and Simon, D.I. Vascular inflammation and repair: implications for re-endothelialization, restenosis, and stent thrombosis. JACC Cardiovasc Interv 4, 1057, 2011.
33. Gojova, A., and Barakat, A.I. Vascular endothelial wound closure under shear stress: role of membrane fluidity and flow-sensitive ion channels. J Appl Physiol 98, 2355, 2005.
34. Ren, X., Tapias, L.F., Jank, B.J., Mathisen, D.J., Lanuti, M., and Ott, H.C. Ex vivo non-invasive assessment of cell viability and proliferation in bio-engineered whole organ constructs. Biomaterials 52, 103, 2015.
35. Sweet, C.S., Emmert, S.E., Seymour, A.A., Stabilito, II, and Oppenheimer, L. Measurement of cardiac output in anesthetized rats by dye dilution using a fiberoptic catheter. J Pharmacol Methods 17, 189, 1987.
36. Lelkes, P.I., and Samet, M.M. Endothelialization of the luminal sac in artificial cardiac prostheses: a challenge for both biologists and engineers. J Biomech Eng 113, 132, 1991.