4-hydroxyphenylacetic acid attenuated inflammation and edema via suppressing HIF-1αin seawater aspiration-induced lung injury in rats

International Journal of Molecular Sciences

Volumn 15, Issue 7, 2014, Pages 12861-12884

  Liu, Zhongyang ^a,b   Xi, Ronggang ^a   Zhang, Zhiran ^a   Li, Wangping ^b   Liu, Yan ^a   Jin, Faguang ^b   Wang, Xiaobo ^a  

^a The 210th Hospital of PLA   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

4 hydroxyphenylacetic acid; Acute lung injury; Hypoxia inducible factor 1 ; Seawater drowning

Indexed keywords

4 HYDROXYPHENYLACETIC ACID; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INITIATION FACTOR 4E; INITIATION FACTOR 4E BINDING PROTEIN 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEIN S6; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; 4-HYDROXYPHENYLACETATE; HIF1A PROTEIN, RAT; PHENYLACETIC ACID DERIVATIVE; SEA WATER; VASCULOTROPIN A;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL CARBON DIOXIDE TENSION; ARTERIAL OXYGEN TENSION; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; HISTOLOGY; HYPOXIA; IMMUNOFLUORESCENCE TEST; LEUKOCYTE COUNT; LUNG ALVEOLUS EPITHELIUM; LUNG EDEMA; LUNG INJURY; LUNG LAVAGE; MACROPHAGE; MALE; NONHUMAN; PERMEABILITY; PNEUMONIA; PROTEIN DEGRADATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEAWATER ASPIRATION INDUCED LUNG INJURY; WESTERN BLOTTING; ACID ASPIRATION; ACUTE LUNG INJURY; ANIMAL; CELL CULTURE; CELL LINE; COMPLICATION; DRUG EFFECTS; EPITHELIUM CELL; GENETICS; INFLAMMATION; LUNG; METABOLISM; PATHOLOGY; PULMONARY EDEMA; SPRAGUE DAWLEY RAT;

ACUTE LUNG INJURY; ANIMALS; CELL LINE; CELLS, CULTURED; EPITHELIAL CELLS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INFLAMMATION; LUNG; MACROPHAGES; MALE; PHENYLACETATES; PULMONARY EDEMA; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY ASPIRATION; SEAWATER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84904646726     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150712861     Document Type: Article

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