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Volumn 1, Issue 4, 2015, Pages 227-237

Visualization of Injectable Hydrogels Using Chemical Exchange Saturation Transfer MRI

Author keywords

chemical exchange saturation transfer; hyaluronic acid; hydrogel; magnetic resonance imaging

Indexed keywords

ARGININE; HYALURONIC ACID;

EID: 84969256325     PISSN: None     EISSN: 23739878     Source Type: Journal    
DOI: 10.1021/ab500097d     Document Type: Article
Times cited : (19)

References (48)
  • 1
    • 77953626607 scopus 로고    scopus 로고
    • Injectable biodegradable hydrogels
    • Nguyen, M. K.; Lee, D. S. Injectable biodegradable hydrogels Macromol. Biosci. 2010, 10, 563-579 10.1002/mabi.200900402
    • (2010) Macromol. Biosci. , vol.10 , pp. 563-579
    • Nguyen, M.K.1    Lee, D.S.2
  • 2
    • 47749146197 scopus 로고    scopus 로고
    • Injectable hydrogels as unique biomedical materials
    • Yu, L.; Ding, J. Injectable hydrogels as unique biomedical materials Chem. Soc. Rev. 2008, 37, 1473-1481 10.1039/b713009k
    • (2008) Chem. Soc. Rev. , vol.37 , pp. 1473-1481
    • Yu, L.1    Ding, J.2
  • 4
    • 84875129654 scopus 로고    scopus 로고
    • Acellular biomaterials: An evolving alternative to cell-based therapies
    • Burdick, J. A.; Mauck, R. L.; Gorman, J. H., III; Gorman, R. C. Acellular biomaterials: An evolving alternative to cell-based therapies Sci. Transl. Med. 2013, 5, 176ps4 10.1126/scitranslmed.3003997
    • (2013) Sci. Transl. Med. , vol.5 , pp. 176ps4
    • Burdick, J.A.1    Mauck, R.L.2    Gorman, J.H.3    Gorman, R.C.4
  • 5
    • 80052049196 scopus 로고    scopus 로고
    • In vivo and in vitro tracking of erosion in biodegradable materials using non-invasive fluorescence imaging
    • Artzi, N.; Oliva, N.; Puron, C.; Shitreet, S.; Artzi, S.; Ramos, A. B.; Groothuis, A.; Sahagian, G.; Edelman, E. R. In vivo and in vitro tracking of erosion in biodegradable materials using non-invasive fluorescence imaging Nat. Mater. 2011, 10, 704-709 10.1038/nmat3095
    • (2011) Nat. Mater. , vol.10 , pp. 704-709
    • Artzi, N.1    Oliva, N.2    Puron, C.3    Shitreet, S.4    Artzi, S.5    Ramos, A.B.6    Groothuis, A.7    Sahagian, G.8    Edelman, E.R.9
  • 6
    • 84883806308 scopus 로고    scopus 로고
    • Sustained release of engineered stromal cell-derived factor 1-alpha from injectable hydrogels effectively recruits endothelial progenitor cells and preserves ventricular function after myocardial infarction
    • MacArthur, J. W., Jr.; Purcell, B. P.; Shudo, Y.; Cohen, J. E.; Fairman, A.; Trubelja, A.; Patel, J.; Hsiao, P.; Yang, E.; Lloyd, K.; Hiesinger, W.; Atluri, P.; Burdick, J. A.; Woo, Y. J. Sustained release of engineered stromal cell-derived factor 1-alpha from injectable hydrogels effectively recruits endothelial progenitor cells and preserves ventricular function after myocardial infarction Circulation 2013, 128, S79-S86 10.1161/CIRCULATIONAHA.112.000343
    • (2013) Circulation , vol.128 , pp. S79-S86
    • MacArthur, J.W.1    Purcell, B.P.2    Shudo, Y.3    Cohen, J.E.4    Fairman, A.5    Trubelja, A.6    Patel, J.7    Hsiao, P.8    Yang, E.9    Lloyd, K.10    Hiesinger, W.11    Atluri, P.12    Burdick, J.A.13    Woo, Y.J.14
  • 7
    • 84901485982 scopus 로고    scopus 로고
    • Immunotherapy with injectable hydrogels to treat obstructive nephropathy
    • Soranno, D. E.; Lu, H. D.; Weber, H. M.; Rai, R.; Burdick, J. A. Immunotherapy with injectable hydrogels to treat obstructive nephropathy J. Biomed. Mater. Res., Part A 2014, 102, 2173-2180 10.1002/jbm.a.34902
    • (2014) J. Biomed. Mater. Res., Part A , vol.102 , pp. 2173-2180
    • Soranno, D.E.1    Lu, H.D.2    Weber, H.M.3    Rai, R.4    Burdick, J.A.5
  • 8
    • 77952353377 scopus 로고    scopus 로고
    • Noninvasive and high-resolution optical monitoring of healing of diabetic dermal excisional wounds implanted with biodegradable in situ gelable hydrogels
    • Yuan, Z.; Zakhaleva, J.; Ren, H.; Liu, J.; Chen, W.; Pan, Y. Noninvasive and high-resolution optical monitoring of healing of diabetic dermal excisional wounds implanted with biodegradable in situ gelable hydrogels Tissue Eng., Part C 2010, 16, 237-247 10.1089/ten.tec.2009.0152
    • (2010) Tissue Eng., Part C , vol.16 , pp. 237-247
    • Yuan, Z.1    Zakhaleva, J.2    Ren, H.3    Liu, J.4    Chen, W.5    Pan, Y.6
  • 9
    • 34250672846 scopus 로고    scopus 로고
    • A systematic approach to the development agents for optical imaging of mouse of fluorescent contrast cancer models
    • Kovar, J. L.; Simpson, M. A.; Schutz-Geschwender, A.; Olive, D. M. A systematic approach to the development agents for optical imaging of mouse of fluorescent contrast cancer models Anal. Biochem. 2007, 367, 1-12 10.1016/j.ab.2007.04.011
    • (2007) Anal. Biochem. , vol.367 , pp. 1-12
    • Kovar, J.L.1    Simpson, M.A.2    Schutz-Geschwender, A.3    Olive, D.M.4
  • 10
    • 0037236238 scopus 로고    scopus 로고
    • Shedding light onto live molecular targets
    • Weissleder, R.; Ntziachristos, V. Shedding light onto live molecular targets Nat. Med. 2003, 9, 123-128 10.1038/nm0103-123
    • (2003) Nat. Med. , vol.9 , pp. 123-128
    • Weissleder, R.1    Ntziachristos, V.2
  • 11
    • 0344848675 scopus 로고    scopus 로고
    • Radiopaque polymeric materials for medical applications - Current aspects of biomaterial research
    • Mottu, F.; Rufenacht, D. A.; Doelker, E. Radiopaque polymeric materials for medical applications-Current aspects of biomaterial research Invest. Radiol. 1999, 34, 323-335 10.1097/00004424-199905000-00001
    • (1999) Invest. Radiol. , vol.34 , pp. 323-335
    • Mottu, F.1    Rufenacht, D.A.2    Doelker, E.3
  • 13
    • 0033363645 scopus 로고    scopus 로고
    • Metal-based x-ray contrast media
    • Yu, S. B.; Watson, A. D. Metal-based x-ray contrast media Chem. Rev. 1999, 99, 2353-2377 10.1021/cr980441p
    • (1999) Chem. Rev. , vol.99 , pp. 2353-2377
    • Yu, S.B.1    Watson, A.D.2
  • 14
    • 70349501571 scopus 로고    scopus 로고
    • Synthesis and characterization of radio-opaque thermosensitive poly[N-isopropylacrylamide-2,2 ′-(ethylenedioxy)bis(ethylamine)-2,3,5-triiodobenzamide]
    • Leon, C. M.; Lee, B. H.; Preul, M.; McLemore, R.; Vernon, B. L. Synthesis and characterization of radio-opaque thermosensitive poly[N-isopropylacrylamide-2,2 ′-(ethylenedioxy)bis(ethylamine)-2,3,5-triiodobenzamide] Polym. Int. 2009, 58, 847-850 10.1002/pi.2616
    • (2009) Polym. Int. , vol.58 , pp. 847-850
    • Leon, C.M.1    Lee, B.H.2    Preul, M.3    McLemore, R.4    Vernon, B.L.5
  • 15
    • 70349345772 scopus 로고    scopus 로고
    • Large animal models of heart failure: A critical link in the translation of basic science to clinical practice
    • Dixon, J. A.; Spinale, F. G. Large animal models of heart failure: A critical link in the translation of basic science to clinical practice Circ.: Heart Failure 2009, 2, 262-271 10.1161/CIRCHEARTFAILURE.108.814459
    • (2009) Circ.: Heart Failure , vol.2 , pp. 262-271
    • Dixon, J.A.1    Spinale, F.G.2
  • 16
    • 84906813462 scopus 로고    scopus 로고
    • Injectable in situ forming hybrid iron oxide-hyaluronic acid hydrogel for magnetic resonance imaging and drug delivery
    • Zhang, Y.; Sun, Y.; Yang, X.; Hilborn, J.; Heerschap, A.; Ossipov, D. A. Injectable in situ forming hybrid iron oxide-hyaluronic acid hydrogel for magnetic resonance imaging and drug delivery Macromol. Biosci. 2014, 14, 1249-1259 10.1002/mabi.201400117
    • (2014) Macromol. Biosci. , vol.14 , pp. 1249-1259
    • Zhang, Y.1    Sun, Y.2    Yang, X.3    Hilborn, J.4    Heerschap, A.5    Ossipov, D.A.6
  • 18
    • 79952782590 scopus 로고    scopus 로고
    • Chemical Exchange Saturation Transfer (CEST): What is in a name and what isn't?
    • van Zijl, P. C. M.; Yadav, N. N. Chemical Exchange Saturation Transfer (CEST): What is in a name and what isn't? Magn. Reson. Med. 2011, 65, 927-948 10.1002/mrm.22761
    • (2011) Magn. Reson. Med. , vol.65 , pp. 927-948
    • Van Zijl, P.C.M.1    Yadav, N.N.2
  • 19
    • 84906081888 scopus 로고    scopus 로고
    • Chemical exchange saturation transfer (CEST) imaging: Description of technique and potential clinical applications
    • Kogan, F.; Hariharan, H.; Reddy, R. Chemical exchange saturation transfer (CEST) imaging: Description of technique and potential clinical applications Curr. Radiol. Rep. 2013, 1, 102-114 10.1007/s40134-013-0010-3
    • (2013) Curr. Radiol. Rep. , vol.1 , pp. 102-114
    • Kogan, F.1    Hariharan, H.2    Reddy, R.3
  • 20
    • 21244455698 scopus 로고    scopus 로고
    • Optimization of the irradiation power in chemical exchange dependent saturation transfer experiments
    • Sun, P.; van Zijl, P.; Zhou, J. Optimization of the irradiation power in chemical exchange dependent saturation transfer experiments J. Magn. Reson. 2005, 175, 193-200 10.1016/j.jmr.2005.04.005
    • (2005) J. Magn. Reson. , vol.175 , pp. 193-200
    • Sun, P.1    Van Zijl, P.2    Zhou, J.3
  • 21
    • 84879542786 scopus 로고    scopus 로고
    • Advantages of paramagnetic chemical exchange saturation transfer (CEST) complexes having slow to intermediate water exchange properties as responsive MRI agents
    • Soesbe, T. C.; Wu, Y.; Dean Sherry, A. Advantages of paramagnetic chemical exchange saturation transfer (CEST) complexes having slow to intermediate water exchange properties as responsive MRI agents NMR Biomed. 2013, 26, 829-838 10.1002/nbm.2874
    • (2013) NMR Biomed. , vol.26 , pp. 829-838
    • Soesbe, T.C.1    Wu, Y.2    Dean Sherry, A.3
  • 22
    • 0034145982 scopus 로고    scopus 로고
    • A new class of contrast agents for MRI based on proton chemical exchange dependent saturation transfer (CEST)
    • Ward, K.; Aletras, A.; Balaban, R. A new class of contrast agents for MRI based on proton chemical exchange dependent saturation transfer (CEST) J. Magn. Reson. 2000, 143, 79-87 10.1006/jmre.1999.1956
    • (2000) J. Magn. Reson. , vol.143 , pp. 79-87
    • Ward, K.1    Aletras, A.2    Balaban, R.3
  • 23
    • 16444362041 scopus 로고    scopus 로고
    • Numerical solution of the Bloch equations provides insights into the optimum design of PARACEST agents for MRI
    • Woessner, D.; Zhang, S.; Merritt, M.; Sherry, A. Numerical solution of the Bloch equations provides insights into the optimum design of PARACEST agents for MRI Magn. Reson. Med. 2005, 53, 790-799 10.1002/mrm.20408
    • (2005) Magn. Reson. Med. , vol.53 , pp. 790-799
    • Woessner, D.1    Zhang, S.2    Merritt, M.3    Sherry, A.4
  • 24
    • 14044274128 scopus 로고    scopus 로고
    • Controlled degradation and mechanical behavior of photopolymerized hyaluronic acid networks
    • Burdick, J. A.; Chung, C.; Jia, X.; Randolph, M. A.; Langer, R. Controlled degradation and mechanical behavior of photopolymerized hyaluronic acid networks Biomacromolecules 2005, 6, 386-391 10.1021/bm049508a
    • (2005) Biomacromolecules , vol.6 , pp. 386-391
    • Burdick, J.A.1    Chung, C.2    Jia, X.3    Randolph, M.A.4    Langer, R.5
  • 25
    • 79953067209 scopus 로고    scopus 로고
    • Hyaluronic acid hydrogels for biomedical applications
    • Burdick, J. A.; Prestwich, G. D. Hyaluronic acid hydrogels for biomedical applications Adv. Mater. 2011, 23, H41-H56 10.1002/adma.201003963
    • (2011) Adv. Mater. , vol.23 , pp. H41-H56
    • Burdick, J.A.1    Prestwich, G.D.2
  • 26
    • 40649092354 scopus 로고    scopus 로고
    • Assessment of glycosaminoglycan concentration in vivo by chemical exchange-dependent saturation transfer (gagCEST)
    • Ling, W.; Regatte, R. R.; Navon, G.; Jerschow, A. Assessment of glycosaminoglycan concentration in vivo by chemical exchange-dependent saturation transfer (gagCEST) Proc. Natl. Acad. Sci. U. S. A. 2008, 105, 2266-2270 10.1073/pnas.0707666105
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 2266-2270
    • Ling, W.1    Regatte, R.R.2    Navon, G.3    Jerschow, A.4
  • 27
    • 84863827545 scopus 로고    scopus 로고
    • Chemical exchange saturation transfer magnetic resonance imaging of human knee cartilage at 3 and 7 T
    • Singh, A.; Haris, M.; Cai, K.; Kassey, V. B.; Kogan, F.; Reddy, D.; Hariharan, H.; Reddy, R. Chemical exchange saturation transfer magnetic resonance imaging of human knee cartilage at 3 and 7 T Magn. Reson. Med. 2012, 68, 588-594 10.1002/mrm.23250
    • (2012) Magn. Reson. Med. , vol.68 , pp. 588-594
    • Singh, A.1    Haris, M.2    Cai, K.3    Kassey, V.B.4    Kogan, F.5    Reddy, D.6    Hariharan, H.7    Reddy, R.8
  • 29
    • 43149099211 scopus 로고    scopus 로고
    • Hydrolytically degradable hyaluronic acid hydrogels with controlled temporal structures
    • Sahoo, S.; Chung, C.; Khetan, S.; Burdick, J. A. Hydrolytically degradable hyaluronic acid hydrogels with controlled temporal structures Biomacromolecules 2008, 9, 1088-1092 10.1021/bm800051m
    • (2008) Biomacromolecules , vol.9 , pp. 1088-1092
    • Sahoo, S.1    Chung, C.2    Khetan, S.3    Burdick, J.A.4
  • 31
    • 53549113087 scopus 로고    scopus 로고
    • New "multicolor" polypeptide diamagnetic chemical exchange saturation transfer (DIACEST) contrast agents for MRI
    • McMahon, M. T.; Gilad, A. A.; DeLiso, M. A.; Berman, S. D. C.; Bulte, J. W. M.; van Zijl, P. C. M. New "multicolor" polypeptide diamagnetic chemical exchange saturation transfer (DIACEST) contrast agents for MRI Magn. Reson. Med. 2008, 60, 803-812 10.1002/mrm.21683
    • (2008) Magn. Reson. Med. , vol.60 , pp. 803-812
    • McMahon, M.T.1    Gilad, A.A.2    Deliso, M.A.3    Berman, S.D.C.4    Bulte, J.W.M.5    Van Zijl, P.C.M.6
  • 32
    • 84897499979 scopus 로고    scopus 로고
    • Incorporation of sulfated hyaluronic acid macromers into degradable hydrogel scaffolds for sustained molecule delivery
    • Purcell, B. P.; Kim, I. L.; Chuo, V.; Guenin, T.; Dorsey, S. M.; Burdick, J. A. Incorporation of sulfated hyaluronic acid macromers into degradable hydrogel scaffolds for sustained molecule delivery Biomater. Sci. 2014, 2, 693-702 10.1039/C3BM60227C
    • (2014) Biomater. Sci. , vol.2 , pp. 693-702
    • Purcell, B.P.1    Kim, I.L.2    Chuo, V.3    Guenin, T.4    Dorsey, S.M.5    Burdick, J.A.6
  • 34
    • 84868150699 scopus 로고    scopus 로고
    • Exchange rates of creatine kinase metabolites: Feasibility of imaging creatine by chemical exchange saturation transfer MRI
    • Haris, M.; Nanga, R. P. R.; Singh, A.; Cai, K.; Kogan, F.; Hariharan, H.; Reddy, R. Exchange rates of creatine kinase metabolites: Feasibility of imaging creatine by chemical exchange saturation transfer MRI NMR Biomed. 2012, 25, 1305-1309 10.1002/nbm.2792
    • (2012) NMR Biomed. , vol.25 , pp. 1305-1309
    • Haris, M.1    Nanga, R.P.R.2    Singh, A.3    Cai, K.4    Kogan, F.5    Hariharan, H.6    Reddy, R.7
  • 36
    • 0029889510 scopus 로고    scopus 로고
    • The dynamics of water-protein interactions
    • Bryant, R. The dynamics of water-protein interactions Annu. Rev. Biophys. Biomol. Struct. 1996, 25, 29-53 10.1146/annurev.bb.25.060196.000333
    • (1996) Annu. Rev. Biophys. Biomol. Struct. , vol.25 , pp. 29-53
    • Bryant, R.1
  • 37
    • 77954567160 scopus 로고    scopus 로고
    • High-throughput screening of chemical exchange saturation transfer MR contrast agents
    • Liu, G.; Gilad, A. A.; Bulte, J. W. M.; van Zijl, P. C. M.; McMahon, M. T. High-throughput screening of chemical exchange saturation transfer MR contrast agents Contrast Media Mol. Imaging 2010, 5, 162-170 10.1002/cmmi.383
    • (2010) Contrast Media Mol. Imaging , vol.5 , pp. 162-170
    • Liu, G.1    Gilad, A.A.2    Bulte, J.W.M.3    Van Zijl, P.C.M.4    McMahon, M.T.5
  • 38
    • 67049160813 scopus 로고    scopus 로고
    • Water saturation shift referencing (WASSR) for chemical exchange saturation transfer (CEST) experiments
    • Kim, M.; Gillen, J.; Landman, B. A.; Zhou, J.; van Zijl, P. C. M. Water saturation shift referencing (WASSR) for chemical exchange saturation transfer (CEST) experiments Magn. Reson. Med. 2009, 61, 1441-1450 10.1002/mrm.21873
    • (2009) Magn. Reson. Med. , vol.61 , pp. 1441-1450
    • Kim, M.1    Gillen, J.2    Landman, B.A.3    Zhou, J.4    Van Zijl, P.C.M.5
  • 39
    • 84874378789 scopus 로고    scopus 로고
    • On B1 inhomogeneity correction of in vivo human brain glutamate chemical exchange saturation transfer contrast at 7T
    • Singh, A.; Cai, K.; Haris, M.; Hariharan, H.; Reddy, R. On B1 inhomogeneity correction of in vivo human brain glutamate chemical exchange saturation transfer contrast at 7T Magn. Reson. Med. 2013, 69, 818-824 10.1002/mrm.24290
    • (2013) Magn. Reson. Med. , vol.69 , pp. 818-824
    • Singh, A.1    Cai, K.2    Haris, M.3    Hariharan, H.4    Reddy, R.5
  • 40
    • 0032112415 scopus 로고    scopus 로고
    • Detection of proton chemical exchange between metabolites and water in biological tissues
    • Guivel-Scharen, V.; Sinnwell, T.; Wolff, S.; Balaban, R. Detection of proton chemical exchange between metabolites and water in biological tissues J. Magn. Reson. 1998, 133, 36-45 10.1006/jmre.1998.1440
    • (1998) J. Magn. Reson. , vol.133 , pp. 36-45
    • Guivel-Scharen, V.1    Sinnwell, T.2    Wolff, S.3    Balaban, R.4
  • 41
    • 33744462402 scopus 로고    scopus 로고
    • Standardization of chemical shifts of TMS and solvent signals in NMR solvents
    • Hoffman, R. Standardization of chemical shifts of TMS and solvent signals in NMR solvents Magn. Reson. Chem. 2006, 44, 606-616 10.1002/mrc.1801
    • (2006) Magn. Reson. Chem. , vol.44 , pp. 606-616
    • Hoffman, R.1
  • 43
    • 84871797365 scopus 로고    scopus 로고
    • Moving from static to dynamic complexity in hydrogel design
    • Burdick, J. A.; Murphy, W. L. Moving from static to dynamic complexity in hydrogel design Nat. Commun. 2012, 3, 1269 10.1038/ncomms2271
    • (2012) Nat. Commun. , vol.3 , pp. 1269
    • Burdick, J.A.1    Murphy, W.L.2
  • 44
    • 0032737267 scopus 로고    scopus 로고
    • Polymeric biomaterials with degradation sites for proteases involved in cell migration
    • West, J.; Hubbell, J. Polymeric biomaterials with degradation sites for proteases involved in cell migration Macromolecules 1999, 32, 241-244 10.1021/ma981296k
    • (1999) Macromolecules , vol.32 , pp. 241-244
    • West, J.1    Hubbell, J.2
  • 45
    • 0030051552 scopus 로고    scopus 로고
    • Proton exchange rates from amino acid side chains - Implications for image contrast
    • Liepinsh, E.; Otting, G. Proton exchange rates from amino acid side chains-Implications for image contrast Magn. Reson. Med. 1996, 35, 30-42 10.1002/mrm.1910350106
    • (1996) Magn. Reson. Med. , vol.35 , pp. 30-42
    • Liepinsh, E.1    Otting, G.2
  • 46
    • 84879555302 scopus 로고    scopus 로고
    • Nuts and bolts of chemical exchange saturation transfer MRI
    • Liu, G.; Song, X.; Chan, K. W. Y.; McMahon, M. T. Nuts and bolts of chemical exchange saturation transfer MRI NMR Biomed. 2013, 26, 810-828 10.1002/nbm.2899
    • (2013) NMR Biomed. , vol.26 , pp. 810-828
    • Liu, G.1    Song, X.2    Chan, K.W.Y.3    McMahon, M.T.4
  • 47
    • 77954567160 scopus 로고    scopus 로고
    • High-throughput screening of chemical exchange saturation transfer MR contrast agents
    • Liu, G.; Gilad, A. A.; Bulte, J. W. M.; van Zijl, P. C. M.; McMahon, M. T. High-throughput screening of chemical exchange saturation transfer MR contrast agents Contrast Media Mol. Imaging 2010, 5, 162-170 10.1002/cmmi.383
    • (2010) Contrast Media Mol. Imaging , vol.5 , pp. 162-170
    • Liu, G.1    Gilad, A.A.2    Bulte, J.W.M.3    Van Zijl, P.C.M.4    McMahon, M.T.5
  • 48
    • 84904262322 scopus 로고    scopus 로고
    • Experimental and computational investigation of altered mechanical properties in myocardium after hydrogel injection
    • Kichula, E. T.; Wang, H.; Dorsey, S. M.; Szczesny, S. E.; Elliott, D. M.; Burdick, J. A.; Wenk, J. F. Experimental and computational investigation of altered mechanical properties in myocardium after hydrogel injection Ann. Biomed. Eng. 2014, 42, 1546-1556 10.1007/s10439-013-0937-9
    • (2014) Ann. Biomed. Eng. , vol.42 , pp. 1546-1556
    • Kichula, E.T.1    Wang, H.2    Dorsey, S.M.3    Szczesny, S.E.4    Elliott, D.M.5    Burdick, J.A.6    Wenk, J.F.7


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