메뉴 건너뛰기




Volumn 116, Issue 2, 2016, Pages 211-222

Whole-body and splanchnic amino acid metabolism in sheep during an acute endotoxin challenge

Author keywords

Amino acids; Endotoxin lipopolysaccharide; Protein synthesis; Sheep; Splanchnic tissues

Indexed keywords

ALBUMIN; CYSTEINE; ENDOTOXIN; GLUCOSE; GLUTAMINE; HEMOGLOBIN; LIPOPOLYSACCHARIDE; METHIONINE; PROLINE; SERINE; THREONINE; AMINO ACID; PLASMA PROTEIN; PROTEIN;

EID: 84969243010     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114516001860     Document Type: Article
Times cited : (16)

References (56)
  • 1
    • 0036109542 scopus 로고    scopus 로고
    • L-arginine supplementation in pigs decreases liver protein turnover and increases hindquarter protein turnover both during and after endotoxemia
    • Bruins MJ, Soeters PB, Lamers WH, et al. (2002) L-arginine supplementation in pigs decreases liver protein turnover and increases hindquarter protein turnover both during and after endotoxemia. Am J Clin Nutr 75, 1031-1044
    • (2002) Am J Clin Nutr , vol.75 , pp. 1031-1044
    • Bruins, M.J.1    Soeters, P.B.2    Lamers, W.H.3
  • 2
    • 84905493056 scopus 로고    scopus 로고
    • Effect of feed restriction on performance and postprandial nutrient metabolism in pigs co-infected with Mycoplasma hyopneumoniae and swine influenza virus
    • Le Floc'h N, Deblanc C, Cariolet R, et al. (2014) Effect of feed restriction on performance and postprandial nutrient metabolism in pigs co-infected with Mycoplasma hyopneumoniae and swine influenza virus. PLOS ONE 9, e104605
    • (2014) PLOS ONE , vol.9 , pp. e104605
    • Le Floc'h, N.1    Deblanc, C.2    Cariolet, R.3
  • 3
    • 84956778805 scopus 로고    scopus 로고
    • Responses in whole-body amino acid kinetics to an acute, sub-clinical endotoxin challenge in lambs
    • Hoskin SO, Bremner DM, Holtrop G, et al. (2016) Responses in whole-body amino acid kinetics to an acute, sub-clinical endotoxin challenge in lambs. Br J Nutr 115, 576-584
    • (2016) Br J Nutr , vol.115 , pp. 576-584
    • Hoskin, S.O.1    Bremner, D.M.2    Holtrop, G.3
  • 4
    • 0034532753 scopus 로고    scopus 로고
    • Endotoxemia affects organ protein metabolism differently during prolonged feeding in pigs
    • Bruins MJ, Soeters PB &Deutz NE (2000) Endotoxemia affects organ protein metabolism differently during prolonged feeding in pigs. J Nutr 130, 3003-3013
    • (2000) J Nutr , vol.130 , pp. 3003-3013
    • Bruins, M.J.1    Soeters, P.B.2    Deutz, N.E.3
  • 5
    • 0038726339 scopus 로고    scopus 로고
    • Mucin production and composition is altered in dextran sulfate sodiuminduced colitis in rats
    • Faure M, Moennoz D, Montigon F, et al. (2003) Mucin production and composition is altered in dextran sulfate sodiuminduced colitis in rats. Dig Dis Sci 48, 1366-1373
    • (2003) Dig Dis Sci , vol.48 , pp. 1366-1373
    • Faure, M.1    Moennoz, D.2    Montigon, F.3
  • 6
    • 0034132042 scopus 로고    scopus 로고
    • Subclinical infection with the nematode Trichostrongylus colubriformis increases gastrointestinal tract leucine metabolism and reduces availability of leucine for other tissues
    • Yu F, Bruce LA, Calder AG, et al. (2000) Subclinical infection with the nematode Trichostrongylus colubriformis increases gastrointestinal tract leucine metabolism and reduces availability of leucine for other tissues. J Anim Sci 78, 380-390
    • (2000) J Anim Sci , vol.78 , pp. 380-390
    • Yu, F.1    Bruce, L.A.2    Calder, A.G.3
  • 7
    • 0028271798 scopus 로고
    • Do the differences between the amino acid compositions of acute-phase and muscle proteins have a bearing on nitrogen loss in traumatic states
    • Reeds PJ, Fjeld CR &Jahoor F (1994) Do the differences between the amino acid compositions of acute-phase and muscle proteins have a bearing on nitrogen loss in traumatic states? J Nutr 124, 906-910
    • (1994) J Nutr , vol.124 , pp. 906-910
    • Reeds, P.J.1    Fjeld, C.R.2    Jahoor, F.3
  • 8
    • 0022980683 scopus 로고
    • Glucose, fatty acid, and urea kinetics in patients with severe pancreatitis the response to substrate infusion and total parenteral nutrition
    • Shaw JH &Wolfe RR (1986) Glucose, fatty acid, and urea kinetics in patients with severe pancreatitis. The response to substrate infusion and total parenteral nutrition. Ann Surg 204, 665-672
    • (1986) Ann Surg , vol.204 , pp. 665-672
    • Shaw, J.H.1    Wolfe, R.R.2
  • 9
    • 0033636495 scopus 로고    scopus 로고
    • Methionine transsulfuration is increased during sepsis in rats
    • Malmezat T, Breuille D, Pouyet C, et al. (2000) Methionine transsulfuration is increased during sepsis in rats. Am J Physiol Endocrinol Metab 279, E1391-E1397
    • (2000) Am J Physiol Endocrinol Metab , vol.279 , pp. E1391-E1397
    • Malmezat, T.1    Breuille, D.2    Pouyet, C.3
  • 10
    • 0029978962 scopus 로고    scopus 로고
    • Determination of protein synthesis in lymphocytes in vivo after surgery
    • Essen P, McNurlan MA, Thorell A, et al. (1996) Determination of protein synthesis in lymphocytes in vivo after surgery. Clin Sci (Lond) 91, 99-106
    • (1996) Clin Sci (Lond) , vol.91 , pp. 99-106
    • Essen, P.1    McNurlan, M.A.2    Thorell, A.3
  • 11
    • 0026787595 scopus 로고
    • Liver cell volume and protein synthesis
    • Stoll B, Gerok W, Lang F, et al. (1992) Liver cell volume and protein synthesis. Biochem J 287, 217-222
    • (1992) Biochem J , vol.287 , pp. 217-222
    • Stoll, B.1    Gerok, W.2    Lang, F.3
  • 12
    • 0031054989 scopus 로고    scopus 로고
    • Splanchnic versus whole-body production of alpha-ketoisocaproate from leucine in the fed state
    • Biolo G &Tessari P (1997) Splanchnic versus whole-body production of alpha-ketoisocaproate from leucine in the fed state. Metabolism 46, 164-167
    • (1997) Metabolism , vol.46 , pp. 164-167
    • Biolo, G.1    Tessari, P.2
  • 13
    • 15644378254 scopus 로고    scopus 로고
    • Threonine and methionine are limiting amino acids for protein synthesis in patients with AIDS
    • Laurichesse H, Tauveron I, Gourdon F, et al. (1998) Threonine and methionine are limiting amino acids for protein synthesis in patients with AIDS. J Nutr 128, 1342-1348
    • (1998) J Nutr , vol.128 , pp. 1342-1348
    • Laurichesse, H.1    Tauveron, I.2    Gourdon, F.3
  • 14
    • 33746232376 scopus 로고    scopus 로고
    • Beneficial effect of amino acid supplementation, especially cysteine, on body nitrogen economy in septic rats
    • Breuille D, Bechereau F, Buffiere C, et al. (2006) Beneficial effect of amino acid supplementation, especially cysteine, on body nitrogen economy in septic rats. Clin Nutr 25, 634-642
    • (2006) Clin Nutr , vol.25 , pp. 634-642
    • Breuille, D.1    Bechereau, F.2    Buffiere, C.3
  • 15
    • 84867086460 scopus 로고    scopus 로고
    • Protective effects of N-acetylcysteine on intestinal functions of piglets challenged with lipopolysaccharide
    • Hou Y, Wang L, Zhang W, et al. (2012) Protective effects of N-acetylcysteine on intestinal functions of piglets challenged with lipopolysaccharide. Amino Acids 43, 1233-1242
    • (2012) Amino Acids , vol.43 , pp. 1233-1242
    • Hou, Y.1    Wang, L.2    Zhang, W.3
  • 16
    • 54749127018 scopus 로고    scopus 로고
    • Clinical use of glutamine supplementation
    • Wernerman J (2008) Clinical use of glutamine supplementation. J Nutr 138, 2040S-2044S
    • (2008) J Nutr , vol.138 , pp. 2040S-2044S
    • Wernerman, J.1
  • 17
    • 0030907771 scopus 로고    scopus 로고
    • Increased whole-body protein and glutamine turnover in advanced cancer is not matched by an increased muscle protein and glutamine turnover
    • de Blaauw I, Heeneman S, Deutz NE, et al. (1997) Increased whole-body protein and glutamine turnover in advanced cancer is not matched by an increased muscle protein and glutamine turnover. J Surg Res 68, 44-55
    • (1997) J Surg Res , vol.68 , pp. 44-55
    • De Blaauw, I.1    Heeneman, S.2    Deutz, N.E.3
  • 18
    • 0029050053 scopus 로고
    • Hepatic detoxification of ammonia in the ovine liver: Possible consequences for amino acid catabolism
    • Lobley GE, Connell A, Lomax MA, et al. (1995) Hepatic detoxification of ammonia in the ovine liver: possible consequences for amino acid catabolism. Br J Nutr 73, 667-685
    • (1995) Br J Nutr , vol.73 , pp. 667-685
    • Lobley, G.E.1    Connell, A.2    Lomax, M.A.3
  • 19
    • 0017115732 scopus 로고
    • Plasma volume measurements in sheep using Evans' blue and continuous blood sampling
    • Mackie WS (1976) Plasma volume measurements in sheep using Evans' blue and continuous blood sampling. Res Vet Sci 21, 108-109
    • (1976) Res Vet Sci , vol.21 , pp. 108-109
    • Mackie, W.S.1
  • 20
    • 0032718811 scopus 로고    scopus 로고
    • Quantitation of blood and plasma amino acids using isotope dilution electron impact gas chromatography/mass spectrometry with U-(13)C amino acids as internal standards
    • Calder AG, Garden KE, Anderson SE, et al. (1999) Quantitation of blood and plasma amino acids using isotope dilution electron impact gas chromatography/mass spectrometry with U-(13)C amino acids as internal standards. Rapid Commun Mass Spectrom 13, 2080-2083
    • (1999) Rapid Commun Mass Spectrom , vol.13 , pp. 2080-2083
    • Calder, A.G.1    Garden, K.E.2    Anderson, S.E.3
  • 21
    • 84878980971 scopus 로고    scopus 로고
    • Impact of short term consumption of diets high in either non-starch polysaccharides or resistant starch in comparison with moderate weight loss on indices of insulin sensitivity in subjects with metabolic syndrome
    • Lobley GE, Holtrop G, Bremner DM, et al. (2013) Impact of short term consumption of diets high in either non-starch polysaccharides or resistant starch in comparison with moderate weight loss on indices of insulin sensitivity in subjects with metabolic syndrome. Nutrients 5, 2144-2172
    • (2013) Nutrients , vol.5 , pp. 2144-2172
    • Lobley, G.E.1    Holtrop, G.2    Bremner, D.M.3
  • 22
    • 0030961790 scopus 로고    scopus 로고
    • Hepatic protein synthesis in the sheep: Effect of intake as monitored by use of stable-isotope-labelled glycine, leucine and phenylalanine
    • Connell A, Calder AG, Anderson SE, et al. (1997) Hepatic protein synthesis in the sheep: effect of intake as monitored by use of stable-isotope-labelled glycine, leucine and phenylalanine. Br J Nutr 77, 255-271
    • (1997) Br J Nutr , vol.77 , pp. 255-271
    • Connell, A.1    Calder, A.G.2    Anderson, S.E.3
  • 23
    • 0031768750 scopus 로고    scopus 로고
    • Transfers of N metabolites across the ovine liver in response to short-term infusions of an amino acid mixture into the mesenteric vein
    • Lobley GE, Bremner DM, Nieto R, et al. (1998) Transfers of N metabolites across the ovine liver in response to short-term infusions of an amino acid mixture into the mesenteric vein. Br J Nutr 80, 371-379
    • (1998) Br J Nutr , vol.80 , pp. 371-379
    • Lobley, G.E.1    Bremner, D.M.2    Nieto, R.3
  • 24
    • 0038059218 scopus 로고    scopus 로고
    • Oxidation of essential amino acids by the ovine gastrointestinal tract
    • Lobley GE, Shen X, Le G, et al. (2003) Oxidation of essential amino acids by the ovine gastrointestinal tract. Br J Nutr 89, 617-630
    • (2003) Br J Nutr , vol.89 , pp. 617-630
    • Lobley, G.E.1    Shen, X.2    Le, G.3
  • 25
    • 0025036483 scopus 로고
    • Characterization of glutamine transport into resting and concanavalin A-stimulated peripheral human lymphocytes
    • Schroder MT, Schafer G &Schauder P (1990) Characterization of glutamine transport into resting and concanavalin A-stimulated peripheral human lymphocytes. J Cell Physiol 145, 155-161
    • (1990) J Cell Physiol , vol.145 , pp. 155-161
    • Schroder, M.T.1    Schafer, G.2    Schauder, P.3
  • 26
    • 0036224623 scopus 로고    scopus 로고
    • Quantitative in vivo assessment of arginine utilization and nitric oxide production in endotoxemia
    • Soeters PB, Hallemeesch MM, Bruins MJ, et al. (2002) Quantitative in vivo assessment of arginine utilization and nitric oxide production in endotoxemia. Am J Surg 183, 480-488
    • (2002) Am J Surg , vol.183 , pp. 480-488
    • Soeters, P.B.1    Hallemeesch, M.M.2    Bruins, M.J.3
  • 27
    • 0028287003 scopus 로고
    • Whole body and splanchnic leucine, phenylalanine, and glucose kinetics during endotoxemia in humans
    • Fong Y, Matthews DE, He W, et al. (1994) Whole body and splanchnic leucine, phenylalanine, and glucose kinetics during endotoxemia in humans. Am J Physiol 266, R419-R425
    • (1994) Am J Physiol , vol.266 , pp. R419-R425
    • Fong, Y.1    Matthews, D.E.2    He, W.3
  • 28
    • 12144273223 scopus 로고    scopus 로고
    • Amino acid metabolism in leg muscle after an endotoxin injection in healthy volunteers
    • Vesali RF, Klaude M, Rooyackers O, et al. (2005) Amino acid metabolism in leg muscle after an endotoxin injection in healthy volunteers. Am J Physiol Endocrinol Metab 288, E360-E364
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , pp. E360-E364
    • Vesali, R.F.1    Klaude, M.2    Rooyackers, O.3
  • 29
    • 0036307851 scopus 로고    scopus 로고
    • Bacterial infection affects protein synthesis in primary lymphoid tissues and circulating lymphocytes of rats
    • Papet I, Ruot B, Breuille D, et al. (2002) Bacterial infection affects protein synthesis in primary lymphoid tissues and circulating lymphocytes of rats. J Nutr 132, 2028-2032
    • (2002) J Nutr , vol.132 , pp. 2028-2032
    • Papet, I.1    Ruot, B.2    Breuille, D.3
  • 30
    • 0036405039 scopus 로고    scopus 로고
    • Response of in vivo protein synthesis in T lymphocytes and leucocytes to an endotoxin challenge in healthy volunteers
    • Januszkiewicz A, Lore K, Essen P, et al. (2002) Response of in vivo protein synthesis in T lymphocytes and leucocytes to an endotoxin challenge in healthy volunteers. Clin Exp Immunol 130, 263-270
    • (2002) Clin Exp Immunol , vol.130 , pp. 263-270
    • Januszkiewicz, A.1    Lore, K.2    Essen, P.3
  • 31
    • 0002064844 scopus 로고
    • Interaction of liver, muscle, and adipose tissue in the regulation of metabolism in response to nutritional and other factors
    • 3rd ed [IM Arias, JL Boyer, N Fausto, WB Jacoby, DA Schachter and DA Shafritz, editors]. New York, NY: Raven Press
    • Hellerstein MK &Munro HN (1994) Interaction of liver, muscle, and adipose tissue in the regulation of metabolism in response to nutritional and other factors. In The Liver: Biology and Pathobiology, 3rd ed. pp. 1169-1181 [IM Arias, JL Boyer, N Fausto, WB Jacoby, DA Schachter and DA Shafritz, editors]. New York, NY: Raven Press
    • (1994) The Liver: Biology and Pathobiology , pp. 1169-1181
    • Hellerstein, M.K.1    Munro, H.N.2
  • 32
    • 0001459114 scopus 로고    scopus 로고
    • The care and feeding of an immune system: An analysis of lysine needs
    • [GE Lobley, A White and JC Macrae, editors]. Wageningen: Wageningen Pers
    • Klasing KC &Calvert CC (1999) The care and feeding of an immune system: an analysis of lysine needs. In Protein Metabolism and Nutrition. EAAP, no. 96, pp. 253-264 [GE Lobley, A White and JC Macrae, editors]. Wageningen: Wageningen Pers
    • (1999) Protein Metabolism and Nutrition. EAAP, No. 96 , pp. 253-264
    • Klasing, K.C.1    Calvert, C.C.2
  • 33
    • 0031966669 scopus 로고    scopus 로고
    • Sustained modifications of protein metabolism in various tissues in a rat model of long-lasting sepsis
    • Breuille D, Arnal M, Rambourdin F, et al. (1998) Sustained modifications of protein metabolism in various tissues in a rat model of long-lasting sepsis. Clin Sci (Lond) 94, 413-423
    • (1998) Clin Sci (Lond) , vol.94 , pp. 413-423
    • Breuille, D.1    Arnal, M.2    Rambourdin, F.3
  • 34
    • 84912101317 scopus 로고    scopus 로고
    • Glycine selectively reduces intestinal injury during endotoxemia
    • Effenberger-Neidnicht K, Jagers J, Verhaegh R, et al. (2014) Glycine selectively reduces intestinal injury during endotoxemia. J Surg Res 192, 592-598
    • (2014) J Surg Res , vol.192 , pp. 592-598
    • Effenberger-Neidnicht, K.1    Jagers, J.2    Verhaegh, R.3
  • 35
    • 0026452917 scopus 로고
    • Postoperative changes in hepatic, intestinal, splenic and muscle fluxes of amino acids and ammonia in pigs
    • Deutz NE, Reijven PL, Athanasas G, et al. (1992) Postoperative changes in hepatic, intestinal, splenic and muscle fluxes of amino acids and ammonia in pigs. Clin Sci (Lond) 83, 607-614
    • (1992) Clin Sci (Lond) , vol.83 , pp. 607-614
    • Deutz, N.E.1    Reijven, P.L.2    Athanasas, G.3
  • 36
    • 0029918587 scopus 로고    scopus 로고
    • Splanchnic-bed transfers of amino acids in sheep blood and plasma, as monitored through use of a multiple U-13C-labelled amino acid mixture
    • Lobley GE, Connell A, Revell DK, et al. (1996) Splanchnic-bed transfers of amino acids in sheep blood and plasma, as monitored through use of a multiple U-13C-labelled amino acid mixture. Br J Nutr 75, 217-235
    • (1996) Br J Nutr , vol.75 , pp. 217-235
    • Lobley, G.E.1    Connell, A.2    Revell, D.K.3
  • 37
    • 0034953505 scopus 로고    scopus 로고
    • Response in hepatic removal of amino acids by the sheep to short-term infusions of varied amounts of an amino acid mixture into the mesenteric vein
    • Lobley GE, Bremner DM &Brown DS (2001) Response in hepatic removal of amino acids by the sheep to short-term infusions of varied amounts of an amino acid mixture into the mesenteric vein. Br J Nutr 85, 689-698
    • (2001) Br J Nutr , vol.85 , pp. 689-698
    • Lobley, G.E.1    Bremner, D.M.2    Brown, D.S.3
  • 38
    • 0036229439 scopus 로고    scopus 로고
    • Glutamine metabolism in ovine splanchnic tissues: Effects of infusion of ammonium bicarbonate or amino acids into the abomasum
    • Nieto R, Obitsu T, Fernandez-Quintela A, et al. (2002) Glutamine metabolism in ovine splanchnic tissues: effects of infusion of ammonium bicarbonate or amino acids into the abomasum. Br J Nutr 87, 357-366
    • (2002) Br J Nutr , vol.87 , pp. 357-366
    • Nieto, R.1    Obitsu, T.2    Fernandez-Quintela, A.3
  • 39
    • 84891017763 scopus 로고    scopus 로고
    • Alterations in glutamine metabolism and its conversion to citrulline in sepsis
    • Kao C, Hsu J, Bandi V, et al. (2013) Alterations in glutamine metabolism and its conversion to citrulline in sepsis. Am J Physiol Endocrinol Metab 304, E1359-E1364
    • (2013) Am J Physiol Endocrinol Metab , vol.304 , pp. E1359-E1364
    • Kao, C.1    Hsu, J.2    Bandi, V.3
  • 40
    • 0032839535 scopus 로고    scopus 로고
    • Human phenylalanine hydroxylase gene expression in kidney and other nonhepatic tissues
    • Lichter-Konecki U, Hipke CM &Konecki DS (1999) Human phenylalanine hydroxylase gene expression in kidney and other nonhepatic tissues. Mol Gen Metab 67, 308-316
    • (1999) Mol Gen Metab , vol.67 , pp. 308-316
    • Lichter-Konecki, U.1    Hipke, C.M.2    Konecki, D.S.3
  • 41
    • 0033864550 scopus 로고    scopus 로고
    • Synthesis rate of plasma albumin is a good indicator of liver albumin synthesis in sepsis
    • Ruot B, Breuille D, Rambourdin F, et al. (2000) Synthesis rate of plasma albumin is a good indicator of liver albumin synthesis in sepsis. Am J Physiol Endocrinol Metab 279, E244-E251
    • (2000) Am J Physiol Endocrinol Metab , vol.279 , pp. E244-E251
    • Ruot, B.1    Breuille, D.2    Rambourdin, F.3
  • 42
    • 0033000786 scopus 로고    scopus 로고
    • The acute-phase protein response to human immunodeficiency virus infection in human subjects
    • Jahoor F, Gazzard B, Phillips G, et al. (1999) The acute-phase protein response to human immunodeficiency virus infection in human subjects. Am J Physiol Endocrinol Metab 276, E1092-E1098
    • (1999) Am J Physiol Endocrinol Metab , vol.276 , pp. E1092-E1098
    • Jahoor, F.1    Gazzard, B.2    Phillips, G.3
  • 43
    • 84858213242 scopus 로고    scopus 로고
    • Development aggravates the severity of skeletal muscle catabolism induced by endotoxemia in neonatal pigs
    • Orellana RA, Suryawan A, Wilson FA, et al. (2012) Development aggravates the severity of skeletal muscle catabolism induced by endotoxemia in neonatal pigs. Am J Physiol Regul Integr Comp Physiol 302, R682-R690
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.302 , pp. R682-R690
    • Orellana, R.A.1    Suryawan, A.2    Wilson, F.A.3
  • 44
    • 84894475239 scopus 로고    scopus 로고
    • Intravenous glutamine administration reduces lung and distal organ injury in malnourished rats with sepsis
    • de Oliveira GP, Silva JD, de Araujo CC, et al. (2014) Intravenous glutamine administration reduces lung and distal organ injury in malnourished rats with sepsis. Shock 41, 222-232
    • (2014) Shock , vol.41 , pp. 222-232
    • De Oliveira, G.P.1    Silva, J.D.2    De Araujo, C.C.3
  • 45
    • 84897079286 scopus 로고    scopus 로고
    • Oral free and dipeptide forms of glutamine supplementation attenuate oxidative stress and inflammation induced by endotoxemia
    • Cruzat VF, Bittencourt A, Scomazzon SP, et al. (2014) Oral free and dipeptide forms of glutamine supplementation attenuate oxidative stress and inflammation induced by endotoxemia. Nutrition 30, 602-611
    • (2014) Nutrition , vol.30 , pp. 602-611
    • Cruzat, V.F.1    Bittencourt, A.2    Scomazzon, S.P.3
  • 46
    • 84930907223 scopus 로고    scopus 로고
    • Effects of enteral nutrition with parenteral glutamine supplementation on the immunological function in septic rats
    • Fan J, Wu L, Li G, et al. (2015) Effects of enteral nutrition with parenteral glutamine supplementation on the immunological function in septic rats. Br J Nutr 113, 1712-1722
    • (2015) Br J Nutr , vol.113 , pp. 1712-1722
    • Fan, J.1    Wu, L.2    Li, G.3
  • 47
    • 0034843181 scopus 로고    scopus 로고
    • Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection
    • Newsholme P (2001) Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection? J Nutr 131, 2515S-2522S
    • (2001) J Nutr , vol.131 , pp. 2515S-2522S
    • Newsholme, P.1
  • 48
    • 79956325558 scopus 로고    scopus 로고
    • Effects of L-arginine pretreatment on nitric oxide metabolism and hepatosplanchnic perfusion during porcine endotoxemia
    • Poeze M, Bruins MJ, Kessels F, et al. (2011) Effects of L-arginine pretreatment on nitric oxide metabolism and hepatosplanchnic perfusion during porcine endotoxemia. Am J Clin Nutr 93, 1237-1247
    • (2011) Am J Clin Nutr , vol.93 , pp. 1237-1247
    • Poeze, M.1    Bruins, M.J.2    Kessels, F.3
  • 49
    • 84930542927 scopus 로고    scopus 로고
    • Dietary supplementation with glutamate precursor alpha-ketoglutarate attenuates lipopolysaccharide-induced liver injury in young pigs
    • Wang L, Hou Y, Yi D, et al. (2015) Dietary supplementation with glutamate precursor alpha-ketoglutarate attenuates lipopolysaccharide-induced liver injury in young pigs. Amino Acids 47, 1309-1318
    • (2015) Amino Acids , vol.47 , pp. 1309-1318
    • Wang, L.1    Hou, Y.2    Yi, D.3
  • 50
    • 45349092821 scopus 로고    scopus 로고
    • Glycine attenuates endotoxin-induced liver injury by downregulating TLR4 signaling in Kupffer cells
    • Xu FL, You HB, Li XH, et al. (2008) Glycine attenuates endotoxin-induced liver injury by downregulating TLR4 signaling in Kupffer cells. Am J Surg 196, 139-148
    • (2008) Am J Surg , vol.196 , pp. 139-148
    • Xu, F.L.1    You, H.B.2    Li, X.H.3
  • 51
    • 0842292525 scopus 로고    scopus 로고
    • The effect of cysteine and glutamine supplementation on sheep infected with Trichostrongylus colubriformis
    • Hoskin SO, Lobley GE, Coop RL, et al. (2002) The effect of cysteine and glutamine supplementation on sheep infected with Trichostrongylus colubriformis. Proc N Z Soc Anim Prod 62, 72-76
    • (2002) Proc N Z Soc Anim Prod , vol.62 , pp. 72-76
    • Hoskin, S.O.1    Lobley, G.E.2    Coop, R.L.3
  • 52
    • 0034109894 scopus 로고    scopus 로고
    • Glutathione turnover is increased during the acute phase of sepsis in rats
    • Malmezat T, Breuille D, Capitan P, et al. (2000) Glutathione turnover is increased during the acute phase of sepsis in rats. J Nutr 130, 1239-1246
    • (2000) J Nutr , vol.130 , pp. 1239-1246
    • Malmezat, T.1    Breuille, D.2    Capitan, P.3
  • 53
    • 66849115545 scopus 로고    scopus 로고
    • Sulfur amino acid deficiency upregulates intestinal methionine cycle activity and suppresses epithelial growth in neonatal pigs
    • Bauchart-Thevret C, Stoll B, Chacko S, et al. (2009) Sulfur amino acid deficiency upregulates intestinal methionine cycle activity and suppresses epithelial growth in neonatal pigs. Am J Physiol Endocrinol Metab 296, E1239-E1250
    • (2009) Am J Physiol Endocrinol Metab , vol.296 , pp. E1239-E1250
    • Bauchart-Thevret, C.1    Stoll, B.2    Chacko, S.3
  • 54
    • 0033429098 scopus 로고    scopus 로고
    • Amino acid availability controls muscle protein metabolism
    • Wolfe RR &Miller SL (1999) Amino acid availability controls muscle protein metabolism. Diabetes Nutr Metab 12, 322-328
    • (1999) Diabetes Nutr Metab , vol.12 , pp. 322-328
    • Wolfe, R.R.1    Miller, S.L.2
  • 55
    • 0034999615 scopus 로고    scopus 로고
    • Whole body and skeletal muscle glutamine metabolism in healthy subjects
    • Mittendorfer B, Volpi E &Wolfe RR (2001) Whole body and skeletal muscle glutamine metabolism in healthy subjects. Am J Physiol Endocrinol Metab 280, E323-E333
    • (2001) Am J Physiol Endocrinol Metab , vol.280 , pp. E323-E333
    • Mittendorfer, B.1    Volpi, E.2    Wolfe, R.R.3
  • 56
    • 0041510532 scopus 로고    scopus 로고
    • Metabolic response of muscle to alanine, glutamine, and valine supplementation during severe illness
    • Gore DC &Wolfe RR (2003) Metabolic response of muscle to alanine, glutamine, and valine supplementation during severe illness. JPEN 27, 307-314
    • (2003) JPEN , vol.27 , pp. 307-314
    • Gore, D.C.1    Wolfe, R.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.