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Volumn 41, Issue 3, 2014, Pages 222-232

Intravenous glutamine administration reduces lung and distal organ injury in malnourished rats with sepsis

Author keywords

Apoptosis; lung injury; lung mechanics; macrophage phenotype; morphometry

Indexed keywords

ADMINISTRATION, INTRAVENOUS; ANIMALS; GENE EXPRESSION REGULATION; GLUTAMINE; INFLAMMATION; INFLAMMATION MEDIATORS; LUNG INJURY; MALE; MALNUTRITION; MULTIPLE ORGAN FAILURE; RATS; RATS, WISTAR; SEPSIS;

EID: 84894475239     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000102     Document Type: Article
Times cited : (25)

References (35)
  • 2
    • 84861342951 scopus 로고    scopus 로고
    • Malnutrition and its impact on cost of hospitalization, length of stay, readmission and 3-year mortality
    • Lim SL, Ong KC, Chan YH, Loke WC, Ferguson M, Daniels L: Malnutrition and its impact on cost of hospitalization, length of stay, readmission and 3-year mortality. Clin Nutr 31(3):345-350, 2012.
    • (2012) Clin Nutr , vol.31 , Issue.3 , pp. 345-350
    • Lim, S.L.1    Ong, K.C.2    Chan, Y.H.3    Loke, W.C.4    Ferguson, M.5    Daniels, L.6
  • 3
    • 0037373605 scopus 로고    scopus 로고
    • Defective antigen-presenting capacity of murine dendritic cells during starvation
    • Abe M, Akbar F, Matsuura B, Horiike N, Onji M: Defective antigen-presenting capacity of murine dendritic cells during starvation. Nutrition 19(3):265-269, 2003.
    • (2003) Nutrition , vol.19 , Issue.3 , pp. 265-269
    • Abe, M.1    Akbar, F.2    Matsuura, B.3    Horiike, N.4    Onji, M.5
  • 4
    • 77957269507 scopus 로고    scopus 로고
    • Study of lymphocyte subpopulations in bone marrow in a model of proteinenergy malnutrition
    • Fock RA, Blatt SL, Beutler B, Pereira J, Tsujita M, de Barros FE, Borelli P: Study of lymphocyte subpopulations in bone marrow in a model of proteinenergy malnutrition. Nutrition 26(10):1021-1028, 2010.
    • (2010) Nutrition , vol.26 , Issue.10 , pp. 1021-1028
    • Fock, R.A.1    Blatt, S.L.2    Beutler, B.3    Pereira, J.4    Tsujita, M.5    De Barros, F.E.6    Borelli, P.7
  • 5
    • 84878536098 scopus 로고    scopus 로고
    • Modulation of the nuclear factor-kappa B (NF-.B) signalling pathway by glutamine in peritoneal macrophages of a murine model of protein malnutrition
    • da Silva Lima F, Rogero MM, Ramos MC, Borelli P, Fock RA: Modulation of the nuclear factor-kappa B (NF-.B) signalling pathway by glutamine in peritoneal macrophages of a murine model of protein malnutrition. Eur J Nutr 52(4): 1343-1351, 2013.
    • (2013) Eur J Nutr , vol.52 , Issue.4 , pp. 1343-1351
    • Da Silva Lima, F.1    Rogero, M.M.2    Ramos, M.C.3    Borelli, P.4    Fock, R.A.5
  • 10
    • 84865524413 scopus 로고    scopus 로고
    • Glutamine modulates sepsisinduced changes to intestinal intraepithelial +%T expression in mice
    • Lee WY, Hu YM, Ko TL, Yeh SL, Yeh CL: Glutamine modulates sepsisinduced changes to intestinal intraepithelial +%T expression in mice. Shock 38(3): 288-293, 2012.
    • (2012) Shock , vol.38 , Issue.3 , pp. 288-293
    • Lee, W.Y.1    Hu, Y.M.2    Ko, T.L.3    Yeh, S.L.4    Yeh, C.L.5
  • 12
    • 83755173518 scopus 로고    scopus 로고
    • Glutamine modulates lipopolysaccharideinduced activation of NF-kappaB via the Akt/mTOR pathway in lung epithelial cells
    • Hou YC, Chiu WC, Yeh CL, Yeh SL: Glutamine modulates lipopolysaccharideinduced activation of NF-kappaB via the Akt/mTOR pathway in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol 302(1):L174-L183, 2012.
    • (2012) Am J Physiol Lung Cell Mol Physiol , vol.302 , Issue.1
    • Hou, Y.C.1    Chiu, W.C.2    Yeh, C.L.3    Yeh, S.L.4
  • 13
    • 20444463157 scopus 로고    scopus 로고
    • Glutamine attenuates lung injury and improves survival after sepsis: Role of enhanced heat shock protein expression
    • Singleton KD, Serkova N, Beckey VE, Wischmeyer PE: Glutamine attenuates lung injury and improves survival after sepsis: role of enhanced heat shock protein expression. Crit Care Med 33(6):1206-1213, 2005.
    • (2005) Crit Care Med , vol.33 , Issue.6 , pp. 1206-1213
    • Singleton, K.D.1    Serkova, N.2    Beckey, V.E.3    Wischmeyer, P.E.4
  • 14
    • 17944401183 scopus 로고    scopus 로고
    • Glutamine attenuates post-traumatic glutathione depletion in human muscle
    • Flaring UB, Rooyackers OE, Wernerman J, Hammarqvist F: Glutamine attenuates post-traumatic glutathione depletion in human muscle. Clin Sci (Lond) 104(3):275-282, 2003.
    • (2003) Clin Sci (Lond) , vol.104 , Issue.3 , pp. 275-282
    • Flaring, U.B.1    Rooyackers, O.E.2    Wernerman, J.3    Hammarqvist, F.4
  • 19
    • 0026455011 scopus 로고
    • Determination of free amino acid enantiomers in rat brain and serum by high-performance liquid chromatography after derivatization with N-tert-butyloxycarbonyl-L-cysteine and o-phthaldialdehyde
    • Hashimoto A, Nishikawa T, Oka T, Takahashi K, Hayashi T: Determination of free amino acid enantiomers in rat brain and serum by high-performance liquid chromatography after derivatization with N-tert-butyloxycarbonyl-L-cysteine and o-phthaldialdehyde. J Chromatogr 582(1-2):41-48, 1992.
    • (1992) J Chromatogr , vol.582 , Issue.1-2 , pp. 41-48
    • Hashimoto, A.1    Nishikawa, T.2    Oka, T.3    Takahashi, K.4    Hayashi, T.5
  • 20
    • 22344449778 scopus 로고    scopus 로고
    • Anti-apoptotic effects of L-glutamine-mediated transcriptional modulation of the heat shock protein 72 during heat shock
    • Ropeleski MJ, Riehm J, Baer KA, Musch MW, Chang EB: Anti-apoptotic effects of L-glutamine-mediated transcriptional modulation of the heat shock protein 72 during heat shock. Gastroenterology 129(1):170-184, 2005.
    • (2005) Gastroenterology , vol.129 , Issue.1 , pp. 170-184
    • Ropeleski, M.J.1    Riehm, J.2    Baer, K.A.3    Musch, M.W.4    Chang, E.B.5
  • 22
    • 0025456060 scopus 로고
    • Glutamine-containing dipeptides in parenteral nutrition
    • Furst P, Albers S, Stehle P: Glutamine-containing dipeptides in parenteral nutrition. JPEN J Parenter Enteral Nutr 14(Suppl 4):118S-124S, 1990.
    • (1990) JPEN J Parenter Enteral Nutr , vol.14 , Issue.SUPPL. 4
    • Furst, P.1    Albers, S.2    Stehle, P.3
  • 23
    • 78650765324 scopus 로고    scopus 로고
    • Glutamine and alanyl-glutamine dipeptide reduce mesenteric plasma extravasation, leukocyte adhesion and tumor necrosis factor-alpha (TNF-alpha) release during experimental endotoxemia
    • Scheibe R, Schade M, Grundling M, Pavlovic D, Starke K, Wendt M, Retter S, Murphy M, Suchner U, Spassov A, et al.: Glutamine and alanyl-glutamine dipeptide reduce mesenteric plasma extravasation, leukocyte adhesion and tumor necrosis factor-alpha (TNF-alpha) release during experimental endotoxemia. J Physiol Pharmacol 60(Suppl 8):19-24, 2009.
    • (2009) J Physiol Pharmacol , vol.60 , Issue.SUPPL. 8 , pp. 19-24
    • Scheibe, R.1    Schade, M.2    Grundling, M.3    Pavlovic, D.4    Starke, K.5    Wendt, M.6    Retter, S.7    Murphy, M.8    Suchner, U.9    Spassov, A.10
  • 24
    • 0035000171 scopus 로고    scopus 로고
    • Glutamine induces heat shock protein and protects against endotoxin shock in the rat
    • Wischmeyer PE, Kahana M, Wolfson R, Ren H, Musch MM, Chang EB: Glutamine induces heat shock protein and protects against endotoxin shock in the rat. J Appl Physiol 90(6):2403-2410, 2001.
    • (2001) J Appl Physiol , vol.90 , Issue.6 , pp. 2403-2410
    • Wischmeyer, P.E.1    Kahana, M.2    Wolfson, R.3    Ren, H.4    Musch, M.M.5    Chang, E.B.6
  • 25
    • 77953066021 scopus 로고    scopus 로고
    • INCAP studies of hematologic and gastrointestinal function in healthy individuals and those with protein-energy malnutrition and infection
    • Viteri FE: INCAP studies of hematologic and gastrointestinal function in healthy individuals and those with protein-energy malnutrition and infection. Food Nutr Bull 31(1):130-140, 2010.
    • (2010) Food Nutr Bull , vol.31 , Issue.1 , pp. 130-140
    • Viteri, F.E.1
  • 26
    • 38349130508 scopus 로고    scopus 로고
    • Dynamic regulation of PGC-1a localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response
    • Anderson RM, Barger JL, Edwards MG, Braun KH, O'Connor CE, Prolla TA, Weindruch R: Dynamic regulation of PGC-1a localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response. Aging Cell 7(1):101-111, 2008.
    • (2008) Aging Cell , vol.7 , Issue.1 , pp. 101-111
    • Anderson, R.M.1    Barger, J.L.2    Edwards, M.G.3    Braun, K.H.4    O'Connor, C.E.5    Prolla, T.A.6    Weindruch, R.7
  • 28
    • 42049109309 scopus 로고    scopus 로고
    • What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, and fibrosis
    • Strieter RM: What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, and fibrosis. Proc Am Thorac Soc 5(3):305-310, 2008.
    • (2008) Proc Am Thorac Soc , vol.5 , Issue.3 , pp. 305-310
    • Strieter, R.M.1
  • 29
    • 34547899107 scopus 로고    scopus 로고
    • Parenteral versus enteral nutrition: Effect on serum cytokines and the hepatic expression of mRNA of suppressor of cytokine signaling proteins, insulin-like growth factor-1 and the growth hormone receptor in rodent sepsis
    • O'LearyMJ, Xue A, Scarlett CJ, Sevette A, Kee AJ, Smith RC: Parenteral versus enteral nutrition: effect on serum cytokines and the hepatic expression of mRNA of suppressor of cytokine signaling proteins, insulin-like growth factor-1 and the growth hormone receptor in rodent sepsis. Crit Care 11(4):R79, 2007.
    • (2007) Crit Care , vol.11 , Issue.4
    • O'Learymj Xue, A.1    Scarlett, C.J.2    Sevette, A.3    Kee, A.J.4    Smith, R.C.5
  • 30
    • 83455196941 scopus 로고    scopus 로고
    • Glutamine administration ameliorates sepsis-induced kidney injury by downregulating the high-mobility group box protein-1Ymediated pathway in mice
    • Hu YM, Pai MH, Yeh CL, Hou YC, Yeh SL: Glutamine administration ameliorates sepsis-induced kidney injury by downregulating the high-mobility group box protein-1Ymediated pathway in mice. Am J Physiol Renal Physiol 302(1):F150-F158, 2012.
    • (2012) Am J Physiol Renal Physiol , vol.302 , Issue.1
    • Hu, Y.M.1    Pai, M.H.2    Yeh, C.L.3    Hou, Y.C.4    Yeh, S.L.5
  • 31
    • 81855200106 scopus 로고    scopus 로고
    • Enhanced HSP70 expression protects against acute lung injury by modulating apoptotic pathways
    • Aschkenasy G, Bromberg Z, Raj N, Deutschman CS, Weiss YG: Enhanced HSP70 expression protects against acute lung injury by modulating apoptotic pathways. PLoS One 6(11):e26956, 2011.
    • (2011) PLoS One , vol.6 , Issue.11
    • Aschkenasy, G.1    Bromberg, Z.2    Raj, N.3    Deutschman, C.S.4    Weiss, Y.G.5
  • 32
    • 66449113122 scopus 로고    scopus 로고
    • Glutamine attenuates tubular cell apoptosis in acute kidney injury via inhibition of the c-Jun N-terminal kinase phosphorylation of 14-3-3
    • Kim YS, Jung MH, Choi MY, Kim YH, Sheverdin V, Kim JH, Ha HJ, Park DJ, Kang SS, Cho GJ, et al.: Glutamine attenuates tubular cell apoptosis in acute kidney injury via inhibition of the c-Jun N-terminal kinase phosphorylation of 14-3-3. Crit Care Med 37(6):2033-2044, 2009.
    • (2009) Crit Care Med , vol.37 , Issue.6 , pp. 2033-2044
    • Kim, Y.S.1    Jung, M.H.2    Choi, M.Y.3    Kim, Y.H.4    Sheverdin, V.5    Kim, J.H.6    Ha, H.J.7    Park, D.J.8    Kang, S.S.9    Cho, G.J.10
  • 33
    • 0035937134 scopus 로고    scopus 로고
    • Glutaminedependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1
    • Ko YG, Kim EY, Kim T, Park H, Park HS, Choi EJ, Kim S: Glutaminedependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1. J Biol Chem 276(8):6030-6036, 2001.
    • (2001) J Biol Chem , vol.276 , Issue.8 , pp. 6030-6036
    • Ko, Y.G.1    Kim, E.Y.2    Kim, T.3    Park, H.4    Park, H.S.5    Choi, E.J.6    Kim, S.7
  • 34
    • 12944265179 scopus 로고    scopus 로고
    • Rapid induction of the intrinsic apoptotic pathway by L-glutamine starvation
    • Paquette JC, Guerin PJ, Gauthier ER: Rapid induction of the intrinsic apoptotic pathway by L-glutamine starvation. J Cell Physiol 202(3):912-921, 2005.
    • (2005) J Cell Physiol , vol.202 , Issue.3 , pp. 912-921
    • Paquette, J.C.1    Guerin, P.J.2    Gauthier, E.R.3
  • 35
    • 0036051315 scopus 로고    scopus 로고
    • Glutamine protects activated human T cells from apoptosis by up-regulating glutathione and Bcl-2 levels
    • Chang WK, Yang KD, Chuang H, Jan JT, Shaio MF: Glutamine protects activated human T cells from apoptosis by up-regulating glutathione and Bcl-2 levels. Clin Immunol 104(2):151-160, 2002.
    • (2002) Clin Immunol , vol.104 , Issue.2 , pp. 151-160
    • Chang, W.K.1    Yang, K.D.2    Chuang, H.3    Jan, J.T.4    Shaio, M.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.