Methionine transsulfuration is increased during sepsis in rats

American Journal of Physiology - Endocrinology and Metabolism

Volumn 279, Issue 6 42-6, 2000, Pages

  Malmezat, Thierry ^a   Breuillé, Denis ^b   Pouyet, Corinne ^b   Buffière, Caroline ^b   Denis, Philippe ^b   Mirand, Philippe Patureau ^a   Obled, Christiane ^a  

^a CEMAGREF   (France)

^b NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

Components of cysteine flux; Cystathionase; Methionine flux

Indexed keywords

CYSTATHIONINE GAMMA LYASE; CYSTEINE; METHIONINE;

AMINO ACID COMPOSITION; AMINO ACID METABOLISM; AMINO ACID TRANSPORT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CRITICAL ILLNESS; HOST RESISTANCE; METHYLATION; NITROGEN BALANCE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN METABOLISM; RAT; SEPSIS; SURGICAL STRESS;

EID: 0033636495     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.2000.279.6.e1391     Document Type: Article

References (35)

1. Increased whole body protein breakdown predominates over increased whole body protein synthesis in multiple organ failure
2. Muscle and plasma amino acids following injury
3. Transamination of methionine in humans
4. Beneficial effect of cysteine supplementation in response to sepsis
5. Sepsis modifies the contribution of different organs to whole-body protein synthesis in rats
6. Deftciencies of essential and conditionally essential nutrients
7. Propargylglycine infusion effects on tissue glutathione levels, plasma amino acid concentrations and tissue morphology in parenterally-fed growing rats
8. Methionine metabolism in mammals
9. Effect of dietary cystine on methionine metabolism
10. Plasma amino acids as predictors of the severity and outcome of sepsis
11. Plasma methionine and cysteine kinetics in response to an intravenous glutathione infusion in adult humans
12. A spectrophotometric method for the direct determination of cysteine in the presence of other naturally occurring amino acids
13. Methionine and cysteine kinetics at different intakes of cystine in healthy adult men
14. Aminoaciduria of severe trauma
15. Increased glutathione turnover during the acute phase of sepsis
16. Cysteine metabolism is modified during the acute phase of sepsis in rats
17. 2+-activated, and ATP-ubiquitin-dependent proteolytic pathways in skeletal muscle from head trauma patients
18. Albumin and fibrinogen syntheses increase while muscle protein synthesis decreases in head-injured patients
19. Glutathione
20. Analysis of tissues and body fluids for nitrogenous constituents
21. Effect of cystine intake on methionine kinetics and oxidation determined with oral tracers of methionine and cysteine in healthy adults
22. Role of the transsulfuration pathway and of gamma-cystathionase activity in the formation of cysteine and sulfate from methionine in rat hepatocytes
23. Prolonged changes in protein and amino acid metabolism after zymosan treatment in rats
24. Constant infusion of tracer
25. Measurement of protein using bicinchoninic acid
26. Effect of cysteine on the metabolism of methionine in rats
27. 13C]methionine
28. 3]methionine kinetics in humans: Methionine conservation and cystine sparing
29. Plasma amino acid profiles in sepsis and stress
30. Impairment of cysteine synthesis from methionine in rats exposed to surgical stress
31. L-Cysteine and glutathione metabolism are impaired in premature infants due to cystathionase deficiency
32. Measurement of the site of incorporation of labelled amino acids into tissue proteins
33. Protein and amino acid metabolism after injury
34. Taurine: Biological update
35. 13C-methionine in patients with severe burn injury