Vitamin D receptor polymorphisms may contribute to asthma risk

Journal of Asthma

Volumn 53, Issue 8, 2016, Pages 790-800

  Han, Ji Chang ^a   Du, Jin ^a   Zhang, Ya Jun ^a   Qi, Guan Bin ^a   Li, Hong Bing ^a   Zhang, Yi Jie ^a   Yu, Xiao Ling ^a  

^a HENAN UNIVERSITY   (China)

Author keywords

allele model; Asthma; case and control study; dominant model; meta analysis; polymorphism; susceptibility; Vitamin D receptor

Indexed keywords

CALCITRIOL RECEPTOR; VITAMIN D RECEPTOR; VDR PROTEIN, HUMAN;

ALLELE; ARTICLE; ASTHMA; BIBLIOGRAPHIC DATABASE; CNKI DATABASE; CORRELATIONAL STUDY; EBSCO DATABASE; GENETIC ASSOCIATION; GENETIC CORRELATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; HIGH RISK POPULATION; HUMAN; MEDLINE; OVID DATABASE; SINGLE NUCLEOTIDE POLYMORPHISM; VIP DATABASE; WANFANG DATABASE; WEB OF SCIENCE; WILEY DATABASE; GENETIC PREDISPOSITION; GENETICS; META ANALYSIS; RISK FACTOR;

ASTHMA; GENETIC PREDISPOSITION TO DISEASE; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, CALCITRIOL; RISK FACTORS;

EID: 84969219604     PISSN: 02770903     EISSN: 15324303     Source Type: Journal    
DOI: 10.3109/02770903.2016.1158267     Document Type: Article

References (58)

1. Wang C, Rose-Zerilli MJ, Koppelman GH, Sandling JK, Holloway JW, Postma DS. Evidence of association between interferon regulatory factor 5 gene polymorphisms and asthma. Gene 2012;504:220–225.
2. L.P.Chung, G.Waterer, P.J.Thompson. Pharmacogenetics of beta2 adrenergic receptor gene polymorphisms, long-acting beta-agonists and asthma. Clin Exp Allergy 2011;41:312–326.
3. S.E.Wenzel. Asthma phenotypes:the evolution from clinical to molecular approaches. Nat Med 2012;18:716–725.
4. C.H.Song, J.K.Lee. Lebrikizumab treatment in adults with asthma. N Engl J Med 2011;365:2433; author reply 2433–2434.
5. A.B.Mukherjee, Z.Zhang. Allergic asthma:influence of genetic and environmental factors,” J Biol Chem 2011;286:32883–32889.
6. M.Bijanzadeh, P.A.Mahesh, N.B.Ramachandra. An understanding of the genetic basis of asthma. Indian J Med Res 2011;134:149–161.
7. Binia A, Van Stiphout N, Liang L, Michel S, Bhavsar PK, Fan Chung K. A polymorphism affecting MYB binding within the promoter of the PDCD4 gene is associated with severe asthma in children. Hum Mutat 2013;34:1131–1139.
8. Harada M, Hirota T, Jodo AI, Hitomi Y, Sakashita M, Tsunoda T. Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma. Am J Respir Cell Mol Biol 2011;44:787–793.
9. Ben-Zvi I, Aranow C, Mackay M, Stanevsky A, Kamen DL, Marinescu LM. The impact of vitamin D on dendritic cell function in patients with systemic lupus erythematosus. PLoS One 2010;5:e9193.
10. S.Baig, T.Moatter. Vitamin D is not just about healthy bones anymore. J Coll Phys Surg Pak 2010;20:355–356.
11. Gezen-Ak D, Dursun E, Bilgic B, Hanagasi H, Ertan T, Gurvit H. Vitamin D receptor gene haplotype is associated with late-onset Alzheimer's disease. Tohoku J Exp Med 2012;228:189–196.
12. Touvier M, Chan DS, Lau R, Aune D, Vieira R, Greenwood DC. Meta-analyses of vitamin D intake, 25-hydroxyvitamin D status, vitamin D receptor polymorphisms, and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 2011;20:1003–1016.
13. M.R.Haussler, P.W.Jurutka, M.Mizwicki, A.W.Norman. Vitamin D receptor (VDR)-mediated actions of 1alpha,25(OH)(2)vitamin D(3):genomic and non-genomic mechanisms. Best Pract Res Clin Endocrinol Metab 2011;25:543–559.
14. M.F.Ismail, H.G.Elnady, E.M.Fouda. Genetic variants in vitamin D pathway in Egyptian asthmatic children:a pilot study. Hum Immunol 2013;74:1659–1664.
15. F.Li, L.Jiang, S.A.Willis-Owen, Y.Zhang, J.Gao. Vitamin D binding protein variants associate with asthma susceptibility in the Chinese Han population. BMC Med Genet 2011;12:103.
16. Wang S, Wang X, Wu J, Lin Y, Chen H, Zheng X. Association of vitamin D receptor gene polymorphism and calcium urolithiasis in the Chinese Han population. Urol Res 2012;40:277–284.
17. Pillai DK, Iqbal SF, Benton AS, Lerner J, Wiles A, Foerster M. Associations between genetic variants in vitamin D metabolism and asthma characteristics in young African Americans:a pilot study. J Investig Med 2011;59, 938–946.
18. A.Berraies, K.Hamzaoui, A.Hamzaoui. Link between vitamin D and airway remodeling. J Asthma Allergy 2014;7:23–30.
19. H.Maalmi, F.H.Sassi, A.Berraies, J.Ammar, K.Hamzaoui, A.Hamzaoui. Association of vitamin D receptor gene polymorphisms with susceptibility to asthma in Tunisian children:A case control study. Hum Immunol 2013;74:234–240.
20. K.Tizaoui, A.Berraies, B.Hamdi, W.Kaabachi, K.Hamzaoui, A.Hamzaoui. Association of Vitamin D receptor gene polymorphisms with asthma risk:systematic review and updated meta-analysis of case-control studies. Lung 2014;192:955–965.
21. Fang WL, Gao LB, Liang WB, Xue H, Bai P, Lv ML. Association analysis of vitamin D receptor gene polymorphisms in chinese population with asthma. Iran J Allergy Asthma Immunol 2009;8:141–147.
22. A.H.Poon, C.Laprise, M.Lemire, A.Montpetit, D.Sinnett, E.Schurr, T.J.Hudson. Association of vitamin d receptor genetic variants with susceptibility to asthma and atopy. Am J Respir Crit Care Med 2004;170:967–973.
23. B.A.Raby, R.Lazarus, E.K.Silverman, S.Lake, C.Lange, M.Wjst, S.T.Weiss. Association of vitamin d receptor gene polymorphisms with childhood and adult asthma. Am J Respir Crit Care Med 2004;170:1057–1065.
24. M.Wjst. Variants in the vitamin D receptor gene and asthma. BMC Genet 2005;6:2.
25. W.Liu, W.C.Cao, C.Y.Zhang, L.Tian, X.M.Wu, J.D.Habbema, Q.M.Zhao, Vdr and nramp1 gene polymorphisms in susceptibility to pulmonary tuberculosis among the chinese han population:A case-control study. Int J Tuberc Lung Dis 2004;8:428–434.
26. L.Bornman, S.J.Campbell, K.Fielding, B.Bah, J.Sillah, P.Gustafson, K.Manneh, Vitamin D receptor polymorphisms and susceptibility to tuberculosis in west africa:A case-control and family study. J Infect Dis 2004;190:1631–1641.
27. R.J.Wilkinson, M.Llewelyn, Z.Toossi, P.Patel, G.Pasvol, A.Lalvani, D.Wright, Influence of vitamin D deficiency and vitamin d receptor polymorphisms on tuberculosis among gujarati asians in west london:A case-control study. Lancet 2000;355:618–621.
28. E.Zintzaras, J.P.Ioannidis. HEGESMA:genome search meta-analysis and heterogeneity testing. Bioinformatics 2005;21:3672–3673.
29. E.Zintzaras, J.P.Ioannidis. Heterogeneity testing in meta-analysis of genome searches. Genet Epidemiol 2005;28:123–137.
30. J.P.Higgins, S.G.Thompson. Quantifying heterogeneity in a meta-analysis. Stat Med 2002;21:1539–1558.
31. A.M.Ferrenberg, R.H.Swendsen. New Monte Carlo technique for studying phase transitions. Phys Rev Lett 1988;61:2635–2638.
32. J.L.Peters, A.J.Sutton, D.R.Jones, K.R.Abrams, L.Rushton. Contour-enhanced meta-analysis funnel plots help distinguish publication bias from other causes of asymmetry. J Clin Epidemiol 2008;61:991–996.
33. M.Egger, G.Davey Smith, M.Schneider, C.Minder. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315:629–634.
34. Raby BA, Lazarus R, Silverman EK, Lake S, Lange C, Wjst M. Association of vitamin D receptor gene polymorphisms with childhood and adult asthma. Am J Respir Crit Care Med 2004;170:1057–1065.
35. A.Saadi, G.Gao, H.Li, C.Wei, Y.Gong, Q.Liu. Association study between vitamin D receptor gene polymorphisms and asthma in the Chinese Han population:a case-control study. BMC Med Genet 2009;10:71.
36. M.Zhao, J.Zhao, Y.Dai. [Effects of VDR gene on the association between blood lead level and childhood asthma]. 2010;04:267–271.
37. Y.Zhen, L.Wang. Association of vitamin D receptor gene polymorphisms with children asthma and wheezy bronchitis. China Prevent Med 2010;11:1055–1058.
38. M.T.Cantorna, J.Zhao, L.Yang. Vitamin D, invariant natural killer T-cells and experimental autoimmune disease. Proc Nutr Soc 2012;71:62–66.
39. T.Tuller, S.Atar, E.Ruppin, M.Gurevich, A.Achiron. Common and specific signatures of gene expression and protein-protein interactions in autoimmune diseases. Genes Immun 2013;14:67–82.
40. Heine G, Hoefer N, Franke A, Nothling U, Schumann RR, Hamann L. Association of vitamin D receptor gene polymorphisms with severe atopic dermatitis in adults. Br J Dermatol 2013;168:855–858.
41. Grant DJ, Hoyo C, Akushevich L, Iversen ES, Whitaker R, Marks J. Vitamin D receptor (VDR) polymorphisms and risk of ovarian cancer in Caucasian and African American women. Gynecol Oncol 2013;129:173–178.
42. L.Huang, C.Liu, G.Liao, X.Yang, X.Tang, J.Chen. Vitamin D receptor gene foki polymorphism contributes to increasing the risk of tuberculosis:An update meta-analysis. Medicine (Baltimore) 2015;94:e2256.
43. H.Zhong, R.Zhou, Y.Feng, G.X.Zheng, Y.Liang, J.Y.Zhang, X.Q.Qin, Association of vitamin d receptor gene polymorphism with the risk of lung cancer:A meta-analysis. J Recept Signal Transduct Res 2014;34:500–505.
44. T.B.Zhou, Z.P.Jiang, M.F.Huang, N.Su. Association of vitamin D receptor Fok1 (rs2228570), TaqI (rs731236) and ApaI (rs7975232) gene polymorphism with the risk of chronic kidney disease. J Recept Signal Transduct Res 2014;35:1–5.
45. Vasilopoulos Y, Sarafidou T, Kotsa K, Papadimitriou M, Goutzelas Y, Stamatis C. VDR TaqI is associated with obesity in the Greek population. Gene 2013;512:237–239.
46. J.Sun. Vitamin D and mucosal immune function. Curr Opin Gastroenterol 2010;26:591–595.
47. T.L.Van Belle, C.Gysemans, C.Mathieu. Vitamin D in autoimmune, infectious and allergic diseases:a vital player?. Best Pract Res Clin Endocrinol Metab 2011;25:617–632.
48. Khoo AL, Joosten I, Michels M, Woestenenk R, Preijers F, He XH. 1,25-Dihydroxyvitamin D3 inhibits proliferation but not the suppressive function of regulatory T cells in the absence of antigen-presenting cells. Immunology 2011;134:459–468.
49. A.Papadopoulou, P.Kouis, N.Middleton, O.Kolokotroni, T.Karpathios, P.Nicolaidou, P.K.Yiallouros. Association of vitamin D receptor gene polymorphisms and vitamin d levels with asthma and atopy in cypriot adolescents:A case-control study. Multidiscip Respir Med 2015;10:26.
50. A.A.Ginde, J.M.Mansbach, C.A.Camargo, Jr. Vitamin D, respiratory infections, and asthma. Curr Allergy Asthma Rep 2009;9:81–87.
51. H.Maalmi, F.H.Sassi, A.Berraies, J.Ammar, K.Hamzaoui, A.Hamzaoui. Association of vitamin D receptor gene polymorphisms with susceptibility to asthma in tunisian children:A case control study. Hum Immunol 2013;74:234–240.
52. L.Man, Z.Zhang, M.Zhang, Y.Zhang, J.Li, N.Zheng, Y.Cao, Association between vitamin d deficiency and insufficiency and the risk of childhood asthma:Evidence from a meta-analysis. Int J Clin Exp Med 2015;8:5699–5706.
53. H.Einisman, M.L.Reyes, J.Angulo, J.Cerda, M.Lopez-Lastra, J.A.Castro-Rodriguez. Vitamin D levels and vitamin D receptor gene polymorphisms in asthmatic children:a case-control study. Pediatr Allergy Immunol, vol., pp., 2015;26:545–550.
54. van Etten E, Verlinden L, Giulietti A, Ramos-Lopez E, Branisteanu DD, Ferreira GB. The vitamin D receptor gene FokI polymorphism:functional impact on the immune system. Eur J Immunol 2007;37:395–405.
55. Bossé Y, Lemire M, Poon AH, Daley D, He JQ, Sandford A. Asthma and genes encoding components of the vitamin D pathway. Respir Res 2009;10:98.
56. Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, Heath S. A large-scale, consortium-based genomewide association study of asthma. N Engl J Med 2010;363:1211–1221.
57. W.L.Fang, L.B.Gao, W.B.Liang, H.Xue, P.Bai, M.L.Lv, Y.Y.Wang, Association analysis of vitamin d receptor gene polymorphisms in chinese population with asthma. Iran J Allergy Asthma Immunol 2009;8:141–147.
58. D.K.Pillai, S.F.Iqbal, A.S.Benton, J.Lerner, A.Wiles, M.Foerster, T.Ozedirne, Associations between genetic variants in vitamin D metabolism and asthma characteristics in young african americans:A pilot study. J Investig Med 2011;59:938–946.