Correlation between laboratory coagulation testing and thromboelastometry is modified during management of trauma patients

Journal of Trauma and Acute Care Surgery

Volumn 81, Issue 2, 2016, Pages 319-327

  David, Jean Stéphane ^b,c   Durand, Maeva ^a,b   Levrat, Albrice ^d   Lefevre, Mathilde ^c   Rugeri, Lucia ^d   Geay Baillat, Marie Odile ^a   Inaba, Kenji ^e   Bouzat, Pierre ^f  

^a EDOUARD HERRIOT HOSPITAL   (France)

^b UNIVERSITÉ LYON 1   (France)

^c CENTRE HOSPITALIER LYON SUD   (France)

^d Centre Hospitalier de la Region d'Annecy   (France)

^e LAC USC MEDICAL CENTER   (United States)

^f HÔPITAL MICHALLON   (France)

Author keywords

Blood product; Coagulopathy; Thromboelastometry; Trauma

Indexed keywords

CYTOCHALASIN D; FIBRINOGEN; FIBRINOGEN CONCENTRATE; FRESH FROZEN PLASMA; THROMBOPLASTIN;

ADULT; ALKALOSIS; ARTICLE; BLOOD CLOTTING TEST; BLOOD CLOTTING TIME; CONTROLLED STUDY; FEMALE; FIBRIN POLYMERIZATION; HEMOSTASIS; HUMAN; INJURY; INJURY SCALE; INTERNATIONAL NORMALIZED RATIO; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; RETROSPECTIVE STUDY; THROMBOCYTE COUNT; THROMBOELASTOGRAPH; THROMBOELASTOGRAPHY; VISCOELASTICITY; BLOOD COAGULATION DISORDERS; COMPLICATION; MIDDLE AGED; PROCEDURES; REGISTER; SENSITIVITY AND SPECIFICITY; WOUNDS AND INJURIES;

ADULT; BLOOD COAGULATION DISORDERS; BLOOD COAGULATION TESTS; FEMALE; HUMANS; INJURY SEVERITY SCORE; MALE; MIDDLE AGED; REGISTRIES; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; THROMBELASTOGRAPHY; WOUNDS AND INJURIES;

EID: 84969160192     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0000000000001109     Document Type: Article

References (41)

1. Davenport R, Manson J, De'Ath H, Platton S, Coates A, Allard S, Hart D, Pearse R, Pasi KJ, MacCallum P, Stanworth S, Brohi K. Functional definition and characterization of acute traumatic coagulopathy. Crit Care Med. 2011;39(12):2652-2658.
2. Bolliger D, Seeberger MD, Tanaka KA. Principles and practice of thromboelastography in clinical coagulation management and transfusion practice. Transfus Med Rev. 2012;26(1):1-13.
3. Fries D, Innerhofer P, Schobersberger W. Time for changing coagulation management in trauma-related massive bleeding. Curr Opin Anaesthesiol. 2009;22(2):267-274.
4. Kashuk JL, Moore EE, Sawyer M, Le T, Johnson J, Biffl WL, Cothren CC, Barnett C, Stahel P, Sillman CC, Sauaia A, Banerjee A. Postinjury coagulopathy management: goal directed resuscitation via POC thrombelastography. Ann Surg. 2010;251(4):604-614.
5. Spahn DR, Bouillon B, Cerny V, Coats TJ, Duranteau J, Fernandez- Mondejar E, Filipescu D, Hunt BJ, Komadina R, Nardi G, Neugebauer E, Ozier Y, Riddez L, Schultz A, Vincent JL, Rossaint R. Management of bleeding and coagulopathy following major trauma: an updated European guideline. Crit Care. 2013;17(2):R76.
6. David JS, Godier A, Dargaud Y, Inaba K. Case scenario: management of trauma-induced coagulopathy in a severe blunt trauma patient. Anesthesiology. 2013;119(1):191-200.
7. Schochl H, Nienaber U, Hofer G, Voelckel W, Jambor C, Scharbert G, Kozek-Langenecker S, Solomon C. Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM)-guided administration of fibrinogen concentrate and prothrombin complex concentrate. Crit Care. 2010;14(2):R55.
8. Schochl H, Nienaber U, Maegele M, Hochleitner G, Primavesi F, Steitz B, Arndt C, Hanke A, Voelckel W, Solomon C. Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy. Crit Care. 2011; 15(2):R83.
9. Nienaber U, Innerhofer P, Westermann I, Schochl H, Attal R, Breitkopf R, Maegele M. The impact of fresh frozen plasma vs coagulation factor concentrates on morbidity and mortality in trauma-associated haemorrhage and massive transfusion. Injury. 2011;42(7):697-701.
10. Gonzalez E, Moore EE, Moore HB, Chapman MP, Chin TL, Ghasabyan A, Wohlauer MV, Barnett CC, Bensard DD, Biffl WL, Burlew CC, Johnson JL, Pieracci FM, Jurkovich GJ, Banerjee A, Silliman CC, Sauaia A. Goaldirected hemostatic resuscitation of trauma-induced coagulopathy: a pragmatic randomized clinical trial comparing a viscoelastic assay to conventional coagulation assays. Ann Surg. 2016;263((6)):1051-1059.
11. Inaba K, Rizoli S, Veigas PV, Callum J, Davenport R, Hess J, Maegele M. 2014 Consensus conference on viscoelastic test-based transfusion guidelines for early trauma resuscitation: report of the panel. J Trauma Acute Care Surg. 2015;78(6):1220-1229.
12. Rugeri L, Levrat A, David JS, Delecroix E, Floccard B, Gros A, Allaouchiche B, Negrier C. Diagnosis of early coagulation abnormalities in trauma patients by rotation thrombelastography. J Thromb Haemost. 2007; 5(2):289-295.
13. Hagemo JS, Christiaans SC, Stanworth SJ, Brohi K, Johansson PI, Goslings JC, Naess PA, Gaarder C. Detection of acute traumatic coagulopathy and massive transfusion requirements by means of rotational thromboelastometry: an international prospective validation study. Crit Care. 2015;19(1):97.
14. Solomon C, Cadamuro J, Ziegler B, Schochl H, Varvenne M, Sorensen B, Hochleitner G, Rahe-Meyer N. A comparison of fibrinogen measurement methods with fibrin clot elasticity assessed by thromboelastometry, before and after administration of fibrinogen concentrate in cardiac surgery patients. Transfusion. 2011;51(8):1695-1706.
15. Floccard B, Rugeri L, Faure A, Saint Denis M, Boyle EM, Peguet O, Levrat A, Guillaume C, Marcotte G, Vulliez A, Hautin E, David JS, Négrier C, Allaouchiche B. Early coagulopathy in trauma patients: an on-scene and hospital admission study. Injury. 2012;43(1):26-32.
16. Collins PW, Solomon C, Sutor K, Crispin D, Hochleitner G, Rizoli S, Schochl H, Schreiber M, Ranucci M. Theoretical modelling of fibrinogen supplementation with therapeutic plasma, cryoprecipitate, or fibrinogen concentrate. Br J Anaesth. 2014;113(4):585-595.
17. Salooja N, Perry DJ. Thrombelastography. Blood Coagul Fibrinolysis. 2001; 12:327-337.
18. Fries D, Innerhofer P, Klingler A, Berresheim U, Mittermayr M, Calatzis A, Schobersberger W. The effect of the combined administration of colloids and lactated Ringer's solution on the coagulation system: an in vitro study using thrombelastograph coagulation analysis (ROTEG). Anesth Analg. 2002;94: 1280-1287.
19. Lang T, Bauters A, Braun SL, Potzsch B, von Pape KW, Kolde HJ, Lakner M. Multi-centre investigation on reference ranges for ROTEM thromboelastometry. Blood Coagul Fibrinolysis. 2005;16:301-310.
20. Baker SP, O'Neill B, Haddon W, Long WB. The Injury Severity Score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma. 1974;14:187-196.
21. Duranteau J, Asehnoune K, Pierre S, Ozier Y, Leone M, Lefrant J-Y. Recommandations sur la réanimation du choc hémorragique. Anesth Réanim. 2015;1(1):62-74.
22. DeLong ER, DeLong DM, Clarke-Pearson DL. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics. 1988;44(3):837-845.
23. Tauber H, Innerhofer P, Breitkopf R, Westermann I, Beer R, El Attal R, Strasak A, Mittermayr M. Prevalence and impact of abnormal ROTEM (R) assays in severe blunt trauma: results of the 'Diagnosis and Treatment of Trauma-Induced Coagulopathy (DIA-TRE-TIC) study'. Br J Anaesth. 2011;107(3):378-387.
24. Haas T, Fries D, Tanaka KA, Asmis L, Curry NS, Schochl H. Usefulness of standard plasma coagulation tests in the management of perioperative coagulopathic bleeding: is there any evidence? Br J Anaesth. 2015;114(2): 217-224.
25. Fowler A, Perry DJ. Laboratory monitoring of haemostasis. Anaesthesia. 2015;70(Suppl 1):68-72, e24.
26. Dunbar NM, Chandler WL. Thrombin generation in trauma patients. Transfusion. 2009;49(12):2652-2660.
27. Peltan ID, Vande Vusse LK, Maier RV, Watkins TR. An international normalized ratio-based definition of acute traumatic coagulopathy is associated with mortality, venous thromboembolism, and multiple organ failure after injury. Crit Care Med. 2015;43(7):1429-1438.
28. Weiss G, Lison S, Spannagl M, Heindl B. Expressiveness of global coagulation parameters in dilutional coagulopathy. Brit J Anaesth. 2010; 105(4):429-436.
29. Cardenas JC, Rahbar E, Pommerening MJ, Baer LA, Matijevic N, Cotton BA, Holcomb JB, Wade CE. Measuring thrombin generation as a tool for predicting hemostatic potential and transfusion requirements following trauma. J Trauma Acute Care Surg. 2014;77(6):839-845.
30. Mosesson MW. Fibrinogen and fibrin structure and functions. J Thromb Haemost. 2005;3(8):1894-1904.
31. Bolliger D, Szlam F, Molinaro RJ, Rahe-Meyer N, Levy JH, Tanaka KA. Finding the optimal concentration range for fibrinogen replacement after severe haemodilution: an in vitro model. Br J Anaesth. 2009;102(6):793-799.
32. Lord JM, Midwinter MJ, Chen YF, Belli A, Brohi K, Kovacs EJ, Koenderman L, Kubes P, Lilford RJ. The systemic immune response to trauma: an overview of pathophysiology and treatment. Lancet. 2014;384 (9952):1455-1465.
33. Mann KG, Brummel K, Butenas S. What is all that thrombin for? J Thromb Haemost. 2003;1(7):1504-1514.
34. Keene DD, Nordmann GR, Woolley T. Rotational thromboelastometryguided trauma resuscitation. Curr Opin Crit Care. 2013;19(6):605-612.
35. Cotton BA, Faz G, Hatch QM, Radwan ZA, Podbielski J, Wade C, Kozar RA, Holcomb JB. Rapid thrombelastography delivers real-time results that predict transfusion within 1 hour of admission. J Trauma. 2011;71(2): 407-414.
36. Holcomb JB, Wade CE, Michalek JE, Chisholm GB, Zarzabal LA, Schreiber MA, Gonzalez EA, Pomper GJ, Perkins JG, Spinella PC, Williams KL, Park MS. Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients. Ann Surg. 2008;248(3): 447-458.
37. Schochl H, Voelckel W, Schlimp CJ. Management of traumatic haemorrhage - the European perspective. Anaesthesia. 2015;70(Suppl 1):102-107, e35-e37.
38. Holcomb JB, Minei KM, Scerbo ML, Radwan ZA, Wade CE, Kozar RA, Gill BS, Albarado R, McNutt MK, Khan S, Adams PR, McCarthy JJ, Cotton BA. Admission rapid thrombelastography can replace conventional coagulation tests in the emergency department: experience with 1974 consecutive trauma patients. Ann Surg. 2012;256(3):476-486.
39. Glas M, Mauer D, Kassas H, Volk T, Kreuer S. Sample transport by pneumatic tube system alters results of multiple electrode aggregometry but not rotational thromboelastometry. Platelets. 2013;24(6):454-461.
40. Martin J, Schuster T, Moessmer G, Kochs EF, Wagner KJ. Alterations in rotation thromboelastometry (ROTEM) parameters: point-of-care testing vs analysis after pneumatic tube system transport. Br J Anaesth. 2012;109(4): 540-545.
41. Hanke AA, Dellweg C, Schochl H, Weber CF, Juttner B, Johanning K, Gorlinger K, Rahe-Meyer N, Kienbaum P. Potential of whole blood coagulation reconstitution by desmopressin and fibrinogen under conditions of hypothermia and acidosis - an in vitro study using rotation thrombelastometry. Scand J Clin Lab Invest. 2011;71(4):292-298.