Neutrophils drive accelerated tumor progression in the collagen-dense mammary tumor microenvironment

Breast Cancer Research

Volumn 18, Issue 1, 2016, Pages

  García Mendoza, María G ^a,b,d   Inman, David R ^a,b   Ponik, Suzanne M ^a,b   Jeffery, Justin J ^b   Sheerar, Dagna S ^b   Van Doorn, Rachel R ^a   Keely, Patricia J ^a,b,c  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN   (United States)

^c University of Wisconsin Health   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Breast cancer; Collagen; Cytokines; Extracellular matrix; MMTV PyVT; Stroma; Tumor associated neutrophils; Tumor microenvironment

Indexed keywords

COLLAGEN TYPE 1; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERFERON RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; LEPTIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; NERVE GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; RANTES; RESISTIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; SOMATOMEDIN; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; VIRUS MIDDLE T ANTIGEN; COLLAGEN; CYTOKINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST DENSITY; BREAST TUMOR; CELL POPULATION; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; METASTASIS; MOLECULAR DYNAMICS; MOUSE; MOUSE MAMMARY TUMOR VIRUS; NEUTROPHIL; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPLEEN; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR VOLUME; ANIMAL; BONE MARROW CELL; DIAGNOSTIC IMAGING; DISEASE COURSE; DISEASE MODEL; EXPERIMENTAL MAMMARY NEOPLASM; GENE EXPRESSION; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; POSITRON EMISSION TOMOGRAPHY; T LYMPHOCYTE SUBPOPULATION; TRANSGENIC MOUSE; TUMOR ASSOCIATED LEUKOCYTE;

ANIMALS; BREAST NEOPLASMS; COLLAGEN; CYTOKINES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION; HUMANS; LYMPHOCYTES, TUMOR-INFILTRATING; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, TRANSGENIC; MYELOID CELLS; NEOPLASM METASTASIS; NEUTROPHIL INFILTRATION; NEUTROPHILS; POSITRON-EMISSION TOMOGRAPHY; SPLEEN; T-LYMPHOCYTE SUBSETS; TUMOR BURDEN; TUMOR MICROENVIRONMENT;

EID: 84968911886     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/s13058-016-0703-7     Document Type: Article

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