Ca2+ is a key factor in α-synuclein-induced neurotoxicity

Journal of Cell Science

Volumn 129, Issue 9, 2016, Pages 1792-1801

  Angelova, Plamena R ^a   Ludtmann, Marthe H R ^a   Horrocks, Mathew H ^b   Negoda, Alexander ^c   Cremades, Nunilo ^b   Klenerman, David ^b   Dobson, Christopher M ^b   Wood, Nicholas W ^a   Pavlov, Evgeny V ^c,d   Gandhi, Sonia ^a   Abramov, Andrey Y ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c DALHOUSIE UNIVERSITY   (Canada)

^d NEW YORK UNIVERSITY   (United States)

Author keywords

Ca2+ signalling; Neuronal death; Parkinson's disease; Synuclein

Indexed keywords

ALPHA SYNUCLEIN; CALCIUM ION; OLIGOMER; CALCIUM; SNCA PROTEIN, RAT;

ANIMAL CELL; ARTICLE; ASTROCYTE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL DEATH; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EXTRACELLULAR CALCIUM; LIPID MEMBRANE; NERVE CELL; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT; AMINO ACID SUBSTITUTION; ANIMAL; CELL CULTURE; GENETICS; METABOLISM; MISSENSE MUTATION; PATHOLOGY; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; SPRAGUE DAWLEY RAT;

ALPHA-SYNUCLEIN; AMINO ACID SUBSTITUTION; ANIMALS; ASTROCYTES; CALCIUM; CALCIUM SIGNALING; CELL DEATH; CELLS, CULTURED; MUTATION, MISSENSE; NEURONS; PARKINSON DISEASE; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84968831207     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.180737     Document Type: Article

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