Detection of 1,N2-propano-2'-deoxyguanosine adducts in genomic DNA by ultrahigh performance liquid chromatography-electrospray ionization-tandem mass spectrometry in combination with stable isotope dilution

Journal of Chromatography A

Volumn 1450, Issue , 2016, Pages 38-44

  Zhang, Ning ^a,b   Song, Yuanyuan ^b   Wu, Danni ^b   Xu, Tian ^b   Lu, Meiling ^c   Zhang, Weibing ^a   Wang, Hailin ^b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b RESEARCH CENTER FOR ECO ENVIRONMENTAL SCIENCES   (China)

^c AGILENT TECHNOLOGIES   (China)

Author keywords

1,N2 propano 2' deoxyguanosine adducts (ProdG adducts); Crotonaldehyde (Cro); Ultrahigh performance liquid chromatography electrospray ionization tandem mass spectrometry (UHPLC ESI MS MS)

Indexed keywords

ALDEHYDES; AMMONIUM BICARBONATE; BIOMOLECULES; CHROMATOGRAPHY; GENES; HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONIZATION; IONIZATION OF LIQUIDS; ISOMERS; ISOTOPES; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; SPECTROMETRY;

1,N2-PROPANO-2'-DEOXYGUANOSINE ADDUCTS (PRODG ADDUCTS); ACCURATE QUANTIFICATIONS; CONCENTRATION-DEPENDENT MANNERS; CROTONALDEHYDE; ESI-MS/MS; STABLE ISOTOPE DILUTION; ULTRA-HIGH PERFORMANCE LIQUID CHROMATOGRAPHIES; UNSATURATED ALDEHYDES;

ELECTROSPRAY IONIZATION;

1,N2 PROPANO 2' DEOXYGUANOSINE; AMMONIUM BICARBONATE; BICARBONATE; CROTONALDEHYDE; DEOXYGUANOSINE; GENOMIC DNA; STABLE ISOTOPE; UNCLASSIFIED DRUG; 1,N2-PROPANO-2'-DEOXYGUANOSINE; 2-BUTENAL; ALDEHYDE; DNA ADDUCT; ISOTOPE;

ARTICLE; CALIBRATION; CONCENTRATION (PARAMETERS); DIASTEREOISOMER; DNA ADDUCT; ELECTROSPRAY MASS SPECTROMETRY; EMBRYO; HUMAN; HUMAN CELL; IONIZATION; ISOTOPE DILUTION ASSAY; ISOTOPE LABELING; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LUNG FIBROBLAST; MEASUREMENT ACCURACY; MRC5 CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; SEPARATION TECHNIQUE; STANDARD; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANALOGS AND DERIVATIVES; ANALYSIS; CELL LINE; CHEMISTRY; DNA DAMAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN GENOME; INDICATOR DILUTION CURVE; PROCEDURES; STEREOISOMERISM;

ALDEHYDES; BICARBONATES; CALIBRATION; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA ADDUCTS; DNA DAMAGE; GENOME, HUMAN; HUMANS; INDICATOR DILUTION TECHNIQUES; ISOTOPES; LIMIT OF DETECTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEREOISOMERISM; TANDEM MASS SPECTROMETRY;

EID: 84968813958     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2016.04.067     Document Type: Article

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