Colorectal cancer cell-derived extracellular vesicles induce phenotypic alteration of T cells into tumor-growth supporting cells with transforming growth factor-β1-mediated suppression

Oncotarget

Volumn 7, Issue 19, 2016, Pages 27033-27043

  Yamada, Nami ^a   Kuranaga, Yuki ^a   Kumazaki, Minami ^a   Shinohara, Haruka ^a   Taniguchi, Kohei ^a   Akao, Yukihiro ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

Colorectal cancer; Exosome; Extracellular vesicle; TGF 1; Tumor stromal interaction

Indexed keywords

CD63 ANTIGEN; CD81 ANTIGEN; CD9 ANTIGEN; CYCLIN D3; CYCLIN DEPENDENT KINASE 4; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 10; MITOGEN ACTIVATED PROTEIN KINASE P38; MYC PROTEIN; PROTEIN KINASE B; PROTEIN P27; SMAD PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CELL COMMUNICATION; CELL TRANSFORMATION; CELL VIABILITY; COLORECTAL CANCER; CONTROLLED STUDY; CTLA 4 GENE; CYTOKINE RELEASE; DOWN REGULATION; ENZYME INACTIVATION; EXOSOME; FEMALE; FOXP3 GENE; GENE; GZMB GENE; HUMAN; HUMAN CELL; IL 10 GENE; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LAG3 GENE; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PHENOTYPE; PRF1 GENE; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE; TUMOR GROWTH; TUMOR MICROENVIRONMENT; UPREGULATION; ANIMAL; CELL CULTURE; CELL PROLIFERATION; COLORECTAL TUMOR; GENETICS; IMMUNOLOGY; JURKAT CELL LINE; METABOLISM; NUDE MOUSE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WESTERN BLOTTING; XENOGRAFT;

ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; COLORECTAL NEOPLASMS; EXTRACELLULAR VESICLES; FEMALE; HUMANS; JURKAT CELLS; MICE, NUDE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA1; TRANSPLANTATION, HETEROLOGOUS;

EID: 84968756405     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.7041     Document Type: Article

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