-
1
-
-
84856784474
-
Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
-
W.AgenoA.S.GallusA.Wittkowsky. Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141:e44S-e88S.
-
(2012)
Chest
, vol.141
, pp. e44S-e88S
-
-
Ageno, W.1
Gallus, A.S.2
Wittkowsky, A.3
-
2
-
-
0037382537
-
American Heart Association/American College of Cardiology Foundation guide to warfarin therapy
-
J.HirshV.FusterJ.AnsellJ.L.Halperin; American Heart Association, American College of Cardiology Foundation. American Heart Association/American College of Cardiology Foundation guide to warfarin therapy. Circulation. 2003;107:1692-1711.
-
(2003)
Circulation
, vol.107
, pp. 1692-1711
-
-
Hirsh, J.1
Fuster, V.2
Ansell, J.3
Halperin, J.L.4
-
3
-
-
84856772158
-
Evidence-based management of anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
-
A.HolbrookS.SchulmanD.M.Witt. Evidence-based management of anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141:e152S-184S.
-
(2012)
Chest
, vol.141
, pp. e152S-184S
-
-
Holbrook, A.1
Schulman, S.2
Witt, D.M.3
-
5
-
-
84937521948
-
-
Accessed February 5, 2016
-
Boehringer Ingelheim Pharmaceuticals, Inc. Pradaxa: highlights of prescribing information. http://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022512s018lbl.pdf. Accessed February 5, 2016.
-
Pradaxa: highlights of prescribing information
-
-
-
6
-
-
84937521948
-
-
Accessed February 5, 2016
-
Bristol-Myers Squibb Company. Eliquis: highlights of prescribing information. http://packageinserts.bms.com/pi/pi_eliquis.pdf. Accessed February 5, 2016.
-
Eliquis: highlights of prescribing information
-
-
-
7
-
-
84937521948
-
-
Accessed February 5, 2016
-
Janssen Pharmaceuticals, Inc. Xarelto: Highlights of prescribing information. http://www.xareltohcp.com/sites/default/files/pdf/xarelto_0.pdf. Accessed February 5, 2016.
-
Xarelto: Highlights of prescribing information
-
-
-
8
-
-
84872124046
-
ASHP therapeutic position statement on the role of pharmacotherapy in preventing venous thromboembolism in hospitalized patients
-
C.E.MahanA.C.SpyropoulosASHP therapeutic position statement on the role of pharmacotherapy in preventing venous thromboembolism in hospitalized patients. Am J Health Syst Pharm. 2012;69:2174-2190.
-
(2012)
Am J Health Syst Pharm
, vol.69
, pp. 2174-2190
-
-
Mahan, C.E.1
Spyropoulos, A.C.2
-
9
-
-
84966880949
-
-
Accessed February 5, 2016
-
Daiichi Sankyo, Inc. SAVAYSA (edoxaban): highlights of prescribing information. http://dsi.com/prescribing-information-portlet/getPIContent?productName=Savaysa&inline=true. Accessed February 5, 2016.
-
SAVAYSA (edoxaban): highlights of prescribing information
-
-
-
10
-
-
84923924319
-
Pros and cons of vitamin K antagonists and non-vitamin K antagonist oral anticoagulants
-
N.RivaW.AgenoPros and cons of vitamin K antagonists and non-vitamin K antagonist oral anticoagulants. Semin Thromb Hemost. 2015;41:178-187.
-
(2015)
Semin Thromb Hemost
, vol.41
, pp. 178-187
-
-
Riva, N.1
Ageno, W.2
-
11
-
-
34548031359
-
The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects
-
J.StangierK.RathgenH.StähleD.GansserW.RothThe pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects. Br J Clin Pharmacol. 2007;64:292-303.
-
(2007)
Br J Clin Pharmacol
, vol.64
, pp. 292-303
-
-
Stangier, J.1
Rathgen, K.2
Stähle, H.3
Gansser, D.4
Roth, W.5
-
12
-
-
25844525489
-
Safety, pharmacodynamics, and pharmacokinetics of single doses of BAY 59-7939, an oral, direct factor Xa inhibitor
-
D.KubitzaM.BeckaB.VoithM.ZuehlsdorfG.WensingSafety, pharmacodynamics, and pharmacokinetics of single doses of BAY 59-7939, an oral, direct factor Xa inhibitor. Clin Pharmacol Ther. 2005;78:412-421.
-
(2005)
Clin Pharmacol Ther
, vol.78
, pp. 412-421
-
-
Kubitza, D.1
Becka, M.2
Voith, B.3
Zuehlsdorf, M.4
Wensing, G.5
-
13
-
-
84878952383
-
Safety, pharmacokinetics and pharmacodynamics of multiple oral doses of apixaban, a factor Xa inhibitor, in healthy subjects
-
C.FrostS.NepalJ.Wang. Safety, pharmacokinetics and pharmacodynamics of multiple oral doses of apixaban, a factor Xa inhibitor, in healthy subjects. Br J Clin Pharmacol. 2013;76:776-786.
-
(2013)
Br J Clin Pharmacol
, vol.76
, pp. 776-786
-
-
Frost, C.1
Nepal, S.2
Wang, J.3
-
14
-
-
84883301339
-
The effects of the antiplatelet agents, aspirin and naproxen, on pharmacokinetics and pharmacodynamics of the anticoagulant edoxaban, a direct factor Xa inhibitor
-
J.MendellF.LeeS.ChenV.WorlandM.ShiM.M.SamamaThe effects of the antiplatelet agents, aspirin and naproxen, on pharmacokinetics and pharmacodynamics of the anticoagulant edoxaban, a direct factor Xa inhibitor. J Cardiovasc Pharmacol. 2013;62:212-221.
-
(2013)
J Cardiovasc Pharmacol
, vol.62
, pp. 212-221
-
-
Mendell, J.1
Lee, F.2
Chen, S.3
Worland, V.4
Shi, M.5
Samama, M.M.6
-
15
-
-
79955531668
-
Effects of food on the pharmacokinetics of edoxaban, an oral direct factor Xa inhibitor, in healthy volunteers
-
J.MendellM.TachibanaM.ShiS.KunitadaEffects of food on the pharmacokinetics of edoxaban, an oral direct factor Xa inhibitor, in healthy volunteers. J Clin Pharmacol. 2011;51:687-694.
-
(2011)
J Clin Pharmacol
, vol.51
, pp. 687-694
-
-
Mendell, J.1
Tachibana, M.2
Shi, M.3
Kunitada, S.4
-
16
-
-
84872260247
-
Apixaban, an oral, direct factor Xa inhibitor: single dose safety, pharmacokinetics, pharmacodynamics and food effect in healthy subjects
-
C.FrostJ.WangS.Nepal. Apixaban, an oral, direct factor Xa inhibitor: single dose safety, pharmacokinetics, pharmacodynamics and food effect in healthy subjects. Br J Clin Pharmacol. 2013;75:476-487.
-
(2013)
Br J Clin Pharmacol
, vol.75
, pp. 476-487
-
-
Frost, C.1
Wang, J.2
Nepal, S.3
-
17
-
-
17644400166
-
Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement
-
J.StangierB.I.ErikssonO.E.Dahl. Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement. J Clin Pharmacol. 2005;45:555-563.
-
(2005)
J Clin Pharmacol
, vol.45
, pp. 555-563
-
-
Stangier, J.1
Eriksson, B.I.2
Dahl, O.E.3
-
19
-
-
84954367009
-
An open-label, phase 1 study to evaluate the effects of hepatic impairment on edoxaban pharmacokinetics and pharmacodynamics
-
J.MendellL.JohnsonS.ChenAn open-label, phase 1 study to evaluate the effects of hepatic impairment on edoxaban pharmacokinetics and pharmacodynamics. J Clin Pharmacol. 2015;55:1395-1405.
-
(2015)
J Clin Pharmacol
, vol.55
, pp. 1395-1405
-
-
Mendell, J.1
Johnson, L.2
Chen, S.3
-
20
-
-
84879486549
-
Effect of hepatic impairment on the pharmacokinetics and pharmacodynamics of a single dose of rivaroxaban, an oral, direct Factor Xa inhibitor
-
D.KubitzaA.RothM.Becka. Effect of hepatic impairment on the pharmacokinetics and pharmacodynamics of a single dose of rivaroxaban, an oral, direct Factor Xa inhibitor. Br J Clin Pharmacol. 2013;76:89-98.
-
(2013)
Br J Clin Pharmacol
, vol.76
, pp. 89-98
-
-
Kubitza, D.1
Roth, A.2
Becka, M.3
-
21
-
-
57449098437
-
Pharmacokinetics and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor, are not affected by moderate hepatic impairment
-
J.StangierH.StähleK.RathgenW.RothK.Shakeri-NejadPharmacokinetics and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor, are not affected by moderate hepatic impairment. J Clin Pharmacol. 2008;48:1411-1419.
-
(2008)
J Clin Pharmacol
, vol.48
, pp. 1411-1419
-
-
Stangier, J.1
Stähle, H.2
Rathgen, K.3
Roth, W.4
Shakeri-Nejad, K.5
-
22
-
-
84934323965
-
Short-term safety and plasma concentrations of edoxaban in Japanese patients with non-valvular atrial fibrillation and severe renal impairment
-
Y.KoretsuneT.YamashitaT.KimuraM.FukuzawaK.AbeM.YasakaShort-term safety and plasma concentrations of edoxaban in Japanese patients with non-valvular atrial fibrillation and severe renal impairment. Circ J. 2015;79:1486-1495.
-
(2015)
Circ J
, vol.79
, pp. 1486-1495
-
-
Koretsune, Y.1
Yamashita, T.2
Kimura, T.3
Fukuzawa, M.4
Abe, K.5
Yasaka, M.6
-
23
-
-
84869109465
-
Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans
-
M.S.BathalaH.MasumotoT.OgumaL.HeC.LowrieJ.MendellPharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans. Drug Metab Dispos. 2012;40:2250-2255.
-
(2012)
Drug Metab Dispos
, vol.40
, pp. 2250-2255
-
-
Bathala, M.S.1
Masumoto, H.2
Oguma, T.3
He, L.4
Lowrie, C.5
Mendell, J.6
-
24
-
-
67650809062
-
Comparative metabolism of 14C-labeled apixaban in mice, rats, rabbits, dogs, and humans
-
D.ZhangK.HeN.Raghavan. Comparative metabolism of 14C-labeled apixaban in mice, rats, rabbits, dogs, and humans. Drug Metab Dispos. 2009;37:1738-1748.
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 1738-1748
-
-
Zhang, D.1
He, K.2
Raghavan, N.3
-
25
-
-
66449099711
-
Metabolism and excretion of rivaroxaban, an oral, direct factor Xa inhibitor, in rats, dogs, and humans
-
C.WeinzT.SchwarzD.KubitzaW.MueckD.LangMetabolism and excretion of rivaroxaban, an oral, direct factor Xa inhibitor, in rats, dogs, and humans. Drug Metab Dispos. 2009;37:1056-1064.
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 1056-1064
-
-
Weinz, C.1
Schwarz, T.2
Kubitza, D.3
Mueck, W.4
Lang, D.5
-
26
-
-
38749131205
-
The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans
-
S.BlechT.EbnerE.Ludwig-SchwellingerJ.StangierW.RothThe metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans. Drug Metab Dispos. 2008;36:386-399.
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 386-399
-
-
Blech, S.1
Ebner, T.2
Ludwig-Schwellinger, E.3
Stangier, J.4
Roth, W.5
-
27
-
-
77953787643
-
Clinical safety, tolerability, pharmacokinetics, and pharmacodynamics of the novel factor Xa inhibitor edoxaban in healthy volunteers
-
K.OgataJ.Mendell-HararyM.Tachibana. Clinical safety, tolerability, pharmacokinetics, and pharmacodynamics of the novel factor Xa inhibitor edoxaban in healthy volunteers. J Clin Pharmacol. 2010;50:743-753.
-
(2010)
J Clin Pharmacol
, vol.50
, pp. 743-753
-
-
Ogata, K.1
Mendell-Harary, J.2
Tachibana, M.3
-
28
-
-
58149458160
-
Apixaban metabolism and pharmacokinetics after oral administration to humans
-
N.RaghavanC.E.FrostZ.Yu. Apixaban metabolism and pharmacokinetics after oral administration to humans. Drug Metab Dispos. 2009;37:74-81.
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 74-81
-
-
Raghavan, N.1
Frost, C.E.2
Yu, Z.3
-
29
-
-
29144518504
-
Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939—an oral, direct Factor Xa inhibitor—after multiple dosing in healthy male subjects
-
D.KubitzaM.BeckaG.WensingB.VoithM.ZuehlsdorfSafety, pharmacodynamics, and pharmacokinetics of BAY 59-7939—an oral, direct Factor Xa inhibitor—after multiple dosing in healthy male subjects. Eur J Clin Pharmacol. 2005;61:873-880.
-
(2005)
Eur J Clin Pharmacol
, vol.61
, pp. 873-880
-
-
Kubitza, D.1
Becka, M.2
Wensing, G.3
Voith, B.4
Zuehlsdorf, M.5
-
30
-
-
77949421739
-
Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: an open-label, parallel-group, single-centre study
-
J.StangierK.RathgenH.StähleD.MazurInfluence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: an open-label, parallel-group, single-centre study. Clin Pharmacokinet. 2010;49:259-268.
-
(2010)
Clin Pharmacokinet
, vol.49
, pp. 259-268
-
-
Stangier, J.1
Rathgen, K.2
Stähle, H.3
Mazur, D.4
-
31
-
-
78649289929
-
Effects of renal impairment on the pharmacokinetics, pharmacodynamics and safety of rivaroxaban, an oral, direct Factor Xa inhibitor
-
D.KubitzaM.BeckaW.Mueck. Effects of renal impairment on the pharmacokinetics, pharmacodynamics and safety of rivaroxaban, an oral, direct Factor Xa inhibitor. Br J Clin Pharmacol. 2010;70:703-712.
-
(2010)
Br J Clin Pharmacol
, vol.70
, pp. 703-712
-
-
Kubitza, D.1
Becka, M.2
Mueck, W.3
-
32
-
-
84964258745
-
Effect of renal impairment on the pharmacokinetics, pharmacodynamics, and safety of apixaban
-
M.ChangZ.YuA.Shenker. Effect of renal impairment on the pharmacokinetics, pharmacodynamics, and safety of apixaban. J Clin Pharmacol. 2016;56:637-645.
-
(2016)
J Clin Pharmacol
, vol.56
, pp. 637-645
-
-
Chang, M.1
Yu, Z.2
Shenker, A.3
-
33
-
-
84864808150
-
Decrease in the oral bioavailability of dabigatran etexilate after co-medication with rifampicin
-
S.HärtterM.Koenen-BergmannA.Sharma. Decrease in the oral bioavailability of dabigatran etexilate after co-medication with rifampicin. Br J Clin Pharmacol. 2012;74:490-500.
-
(2012)
Br J Clin Pharmacol
, vol.74
, pp. 490-500
-
-
Härtter, S.1
Koenen-Bergmann, M.2
Sharma, A.3
-
34
-
-
84877289110
-
Co-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects
-
W.MueckD.KubitzaM.BeckaCo-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects. Br J Clin Pharmacol. 2013;76:455-466.
-
(2013)
Br J Clin Pharmacol
, vol.76
, pp. 455-466
-
-
Mueck, W.1
Kubitza, D.2
Becka, M.3
-
35
-
-
76749166335
-
In vitro assessment of metabolic drug-drug interaction potential of apixaban through cytochrome P450 phenotyping, inhibition, and induction studies
-
L.WangD.ZhangN.Raghavan. In vitro assessment of metabolic drug-drug interaction potential of apixaban through cytochrome P450 phenotyping, inhibition, and induction studies. Drug Metab Dispos. 2010;38:448-458.
-
(2010)
Drug Metab Dispos
, vol.38
, pp. 448-458
-
-
Wang, L.1
Zhang, D.2
Raghavan, N.3
-
36
-
-
84885129987
-
Drug-drug interaction studies of cardiovascular drugs involving P-glycoprotein, an efflux transporter, on the pharmacokinetics of edoxaban, an oral factor Xa inhibitor
-
J.MendellH.ZahirN.Matsushima. Drug-drug interaction studies of cardiovascular drugs involving P-glycoprotein, an efflux transporter, on the pharmacokinetics of edoxaban, an oral factor Xa inhibitor. Am J Cardiovasc Drugs. 2013;13:331-342.
-
(2013)
Am J Cardiovasc Drugs
, vol.13
, pp. 331-342
-
-
Mendell, J.1
Zahir, H.2
Matsushima, N.3
-
37
-
-
33645779998
-
Effect of food, an antacid, and the H2 antagonist ranitidine on the absorption of BAY 59-7939 (rivaroxaban), an oral, direct factor Xa inhibitor, in healthy subjects
-
D.KubitzaM.BeckaM.ZuehlsdorfW.MueckEffect of food, an antacid, and the H2 antagonist ranitidine on the absorption of BAY 59-7939 (rivaroxaban), an oral, direct factor Xa inhibitor, in healthy subjects. J Clin Pharmacol. 2006;46:549-558.
-
(2006)
J Clin Pharmacol
, vol.46
, pp. 549-558
-
-
Kubitza, D.1
Becka, M.2
Zuehlsdorf, M.3
Mueck, W.4
-
38
-
-
84880327613
-
Oral apixaban for the treatment of acute venous thromboembolism
-
G.AgnelliH.R.BullerA.Cohen. Oral apixaban for the treatment of acute venous thromboembolism. N Engl J Med. 2013;369:799-808.
-
(2013)
N Engl J Med
, vol.369
, pp. 799-808
-
-
Agnelli, G.1
Buller, H.R.2
Cohen, A.3
-
39
-
-
78650619315
-
Oral rivaroxaban for symptomatic venous thromboembolism
-
R.BauersachsS.D.BerkowitzB.Brenner. Oral rivaroxaban for symptomatic venous thromboembolism. N Engl J Med. 2010;363:2499-2510.
-
(2010)
N Engl J Med
, vol.363
, pp. 2499-2510
-
-
Bauersachs, R.1
Berkowitz, S.D.2
Brenner, B.3
-
40
-
-
84859385808
-
Oral rivaroxaban for the treatment of symptomatic pulmonary embolism
-
H.R.BüllerM.H.PrinsA.W.Lensin. Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. N Engl J Med. 2012;366:1287-1297.
-
(2012)
N Engl J Med
, vol.366
, pp. 1287-1297
-
-
Büller, H.R.1
Prins, M.H.2
Lensin, A.W.3
-
41
-
-
84885618705
-
Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism
-
Hokusai-VTE Investigators; H.R.BüllerH.DécoususM.A.Grosso. Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism. N Engl J Med. 2013;369:1406-1415.
-
(2013)
N Engl J Med
, vol.369
, pp. 1406-1415
-
-
Büller, H.R.1
Décousus, H.2
Grosso, M.A.3
-
42
-
-
84894295323
-
Treatment of acute venous thromboembolism with dabigatran or warfarin and pooled analysis
-
S.SchulmanA.K.KakkarS.Z.Goldhaber. Treatment of acute venous thromboembolism with dabigatran or warfarin and pooled analysis. Circulation. 2014;129:764-772.
-
(2014)
Circulation
, vol.129
, pp. 764-772
-
-
Schulman, S.1
Kakkar, A.K.2
Goldhaber, S.Z.3
-
43
-
-
71849117615
-
Dabigatran versus warfarin in the treatment of acute venous thromboembolism
-
S.SchulmanC.KearonA.K.Kakkar. Dabigatran versus warfarin in the treatment of acute venous thromboembolism. N Engl J Med. 2009;361:2342-2352.
-
(2009)
N Engl J Med
, vol.361
, pp. 2342-2352
-
-
Schulman, S.1
Kearon, C.2
Kakkar, A.K.3
-
44
-
-
84866682194
-
Benchmark for time in therapeutic range in venous thromboembolism: a systematic review and meta-analysis
-
P.M.ErkensH.ten CateH.R.BullerM.H.PrinsBenchmark for time in therapeutic range in venous thromboembolism: a systematic review and meta-analysis. PLoS One. 2012;7:e42269.
-
(2012)
PLoS One
, vol.7
, pp. e42269
-
-
Erkens, P.M.1
ten Cate, H.2
Buller, H.R.3
Prins, M.H.4
-
45
-
-
77956232181
-
Warfarin therapy in patients with venous thromboembolism: patterns of use and predictors of clinical outcomes
-
S.B.DeitelzweigJ.LinC.KreilickM.HusseinD.BattlemanWarfarin therapy in patients with venous thromboembolism: patterns of use and predictors of clinical outcomes. Adv Ther. 2010;27:623-633.
-
(2010)
Adv Ther
, vol.27
, pp. 623-633
-
-
Deitelzweig, S.B.1
Lin, J.2
Kreilick, C.3
Hussein, M.4
Battleman, D.5
-
46
-
-
84884336961
-
Oral rivaroxaban versus standard therapy for the treatment of symptomatic venous thromboembolism: a pooled analysis of the EINSTEIN-DVT and PE randomized studies
-
M.H.PrinsA.W.LensingR.Bauersachs. Oral rivaroxaban versus standard therapy for the treatment of symptomatic venous thromboembolism: a pooled analysis of the EINSTEIN-DVT and PE randomized studies. Thromb J. 2013;11:21.
-
(2013)
Thromb J
, vol.11
, pp. 21
-
-
Prins, M.H.1
Lensing, A.W.2
Bauersachs, R.3
-
47
-
-
84874003257
-
Extended use of dabigatran, warfarin, or placebo in venous thromboembolism
-
S.SchulmanC.KearonA.K.Kakkar. Extended use of dabigatran, warfarin, or placebo in venous thromboembolism. N Engl J Med. 2013;368:709-718.
-
(2013)
N Engl J Med
, vol.368
, pp. 709-718
-
-
Schulman, S.1
Kearon, C.2
Kakkar, A.K.3
-
48
-
-
84873596181
-
Apixaban for extended treatment of venous thromboembolism
-
G.AgnelliH.R.BullerA.Cohen. Apixaban for extended treatment of venous thromboembolism. N Engl J Med. 2013;368:699-708.
-
(2013)
N Engl J Med
, vol.368
, pp. 699-708
-
-
Agnelli, G.1
Buller, H.R.2
Cohen, A.3
-
49
-
-
84966900175
-
Antithrombotic therapy for VTE disease: Chest guideline
-
C.KearonE.A.AklJ.Ornelas. Antithrombotic therapy for VTE disease: Chest guideline. Chest. In press.
-
Chest
-
-
Kearon, C.1
Akl, E.A.2
Ornelas, J.3
-
50
-
-
84931559772
-
Overview of the new oral anticoagulants: opportunities and challenges
-
C.H.YehK.HoggJ.I.WeitzOverview of the new oral anticoagulants: opportunities and challenges. Arterioscler Thromb Vasc Biol. 2015;35:1056-1065.
-
(2015)
Arterioscler Thromb Vasc Biol
, vol.35
, pp. 1056-1065
-
-
Yeh, C.H.1
Hogg, K.2
Weitz, J.I.3
-
51
-
-
84946208087
-
Updated European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist anticoagulants in patients with non-valvular atrial fibrillation
-
H.HeidbuchelP.VerhammeM.Alings. Updated European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist anticoagulants in patients with non-valvular atrial fibrillation. Europace. 2015;17:1467-1507.
-
(2015)
Europace
, vol.17
, pp. 1467-1507
-
-
Heidbuchel, H.1
Verhamme, P.2
Alings, M.3
-
52
-
-
84931567140
-
Direct oral anticoagulants (DOACs) in the laboratory: 2015 review
-
D.M.AdcockR.GosselinDirect oral anticoagulants (DOACs) in the laboratory: 2015 review. Thromb Res. 2015;136:7-12.
-
(2015)
Thromb Res
, vol.136
, pp. 7-12
-
-
Adcock, D.M.1
Gosselin, R.2
-
53
-
-
84859178003
-
How I treat with anticoagulants in 2012: new and old anticoagulants, and when and how to switch
-
S.SchulmanM.A.CrowtherHow I treat with anticoagulants in 2012: new and old anticoagulants, and when and how to switch. Blood. 2012;119:3016-3023.
-
(2012)
Blood
, vol.119
, pp. 3016-3023
-
-
Schulman, S.1
Crowther, M.A.2
-
55
-
-
84907202540
-
Direct oral anticoagulants compared with vitamin K antagonists for acute venous thromboembolism: evidence from phase 3 trials
-
N.van EsM.CoppensS.SchulmanS.MiddeldorpH.R.BullerDirect oral anticoagulants compared with vitamin K antagonists for acute venous thromboembolism: evidence from phase 3 trials. Blood. 2014;124:1968-1975.
-
(2014)
Blood
, vol.124
, pp. 1968-1975
-
-
van Es, N.1
Coppens, M.2
Schulman, S.3
Middeldorp, S.4
Buller, H.R.5
-
57
-
-
84862894480
-
Apixaban: a novel oral inhibitor of factor Xa
-
E.NutescuApixaban: a novel oral inhibitor of factor Xa. Am J Health Syst Pharm. 2012;69:1113-1126.
-
(2012)
Am J Health Syst Pharm
, vol.69
, pp. 1113-1126
-
-
Nutescu, E.1
-
58
-
-
84905044202
-
Edoxaban: a focused review of its clinical pharmacology
-
G.Y.LipG.AgnelliEdoxaban: a focused review of its clinical pharmacology. Eur Heart J. 2014;35:1844-1855.
-
(2014)
Eur Heart J
, vol.35
, pp. 1844-1855
-
-
Lip, G.Y.1
Agnelli, G.2
-
60
-
-
84875071896
-
Oral bioavailability of dabigatran etexilate (Pradaxa(®)) after co-medication with verapamil in healthy subjects
-
S.HärtterR.SennewaldG.NehmizP.ReillyOral bioavailability of dabigatran etexilate (Pradaxa(®)) after co-medication with verapamil in healthy subjects. Br J Clin Pharmacol. 2013;75:1053-1062.
-
(2013)
Br J Clin Pharmacol
, vol.75
, pp. 1053-1062
-
-
Härtter, S.1
Sennewald, R.2
Nehmiz, G.3
Reilly, P.4
-
61
-
-
85095607046
-
-
Accessed February 5, 2016
-
Medscape. Pradaxa (dabigatran) dosing, indications, interactions, adverse effects, and more. http://reference.medscape.com/drug/dabigatran-342135. Accessed February 5, 2016.
-
Pradaxa (dabigatran) dosing, indications, interactions, adverse effects, and more
-
-
-
62
-
-
84859032875
-
Effect of co-administration of rivaroxaban and clopidogrel on bleeding time, pharmacodynamics and pharmacokinetics: a phase I study
-
D.KubitzaM.BeckaW.MückS.SchwersEffect of co-administration of rivaroxaban and clopidogrel on bleeding time, pharmacodynamics and pharmacokinetics: a phase I study. Pharmaceuticals (Basel). 2012;5:279-296.
-
(2012)
Pharmaceuticals (Basel)
, vol.5
, pp. 279-296
-
-
Kubitza, D.1
Becka, M.2
Mück, W.3
Schwers, S.4
-
63
-
-
80052592404
-
Rivaroxaban versus warfarin in nonvalvular atrial fibrillation
-
M.R.PatelK.W.MahaffeyJ.Garg. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med. 2011;365:883-891.
-
(2011)
N Engl J Med
, vol.365
, pp. 883-891
-
-
Patel, M.R.1
Mahaffey, K.W.2
Garg, J.3
-
64
-
-
84873569160
-
Concomitant use of antiplatelet therapy with dabigatran or warfarin in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial
-
A.L.DansS.J.ConnollyL.Wallentin. Concomitant use of antiplatelet therapy with dabigatran or warfarin in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial. Circulation. 2013;127:634-640.
-
(2013)
Circulation
, vol.127
, pp. 634-640
-
-
Dans, A.L.1
Connolly, S.J.2
Wallentin, L.3
-
65
-
-
84900992940
-
Major bleeding in patients with atrial fibrillation receiving apixaban or warfarin: The ARISTOTLE Trial (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation): predictors, characteristics, and clinical outcomes
-
E.M.HylekC.HeldJ.H.Alexander. Major bleeding in patients with atrial fibrillation receiving apixaban or warfarin: The ARISTOTLE Trial (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation): predictors, characteristics, and clinical outcomes. J Am Coll Cardiol. 2014;63:2141-2147.
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 2141-2147
-
-
Hylek, E.M.1
Held, C.2
Alexander, J.H.3
-
67
-
-
84880571372
-
Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors: proposals of the working group on perioperative haemostasis (GIHP): March 2013
-
G.PernodP.AlbaladejoA.Godier. Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors: proposals of the working group on perioperative haemostasis (GIHP): March 2013. Arch Cardiovasc Dis. 2013;106:382-393.
-
(2013)
Arch Cardiovasc Dis
, vol.106
, pp. 382-393
-
-
Pernod, G.1
Albaladejo, P.2
Godier, A.3
-
68
-
-
84966965959
-
-
Accessed February 5, 2016
-
Boehringer Ingelheim Pharmaceuticals, Inc. Praxbind: highlights of prescribing information. http://www.accessdata.fda.gov/drugsatfda_docs/label/2015/761025lbl.pdf. Accessed February 5, 2016.
-
Praxbind: highlights of prescribing information
-
-
-
69
-
-
84879548455
-
A specific antidote for dabigatran: functional and structural characterization
-
F.SchieleJ.van RynK.Canada. A specific antidote for dabigatran: functional and structural characterization. Blood. 2013;121:3554-3562.
-
(2013)
Blood
, vol.121
, pp. 3554-3562
-
-
Schiele, F.1
van Ryn, J.2
Canada, K.3
-
71
-
-
84878460192
-
A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa
-
G.LuF.R.DeGuzmanS.J.Hollenbach. A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa. Nat Med. 2013;19:446-451.
-
(2013)
Nat Med
, vol.19
, pp. 446-451
-
-
Lu, G.1
DeGuzman, F.R.2
Hollenbach, S.J.3
-
72
-
-
84929242564
-
-
Paper presented at: American Heart Association Scientific Sessions, Chicago, IL:
-
M.CrowtherG.LevyG.Lu. ANNEXA-A: a phase 3 randomized, double-blind, placebo-controlled trial, demonstrating reversal of apixaban-induced anticoagulation in older subjects by andexanet alfa (PRT064445), a universal antidote for factor Xa (fXa) inhibitors. Paper presented at: American Heart Association Scientific Sessions; November 15-19, 2014; Chicago, IL.
-
ANNEXA-A: a phase 3 randomized, double-blind, placebo-controlled trial, demonstrating reversal of apixaban-induced anticoagulation in older subjects by andexanet alfa (PRT064445), a universal antidote for factor Xa (fXa) inhibitors
-
-
Crowther, M.1
Levy, G.2
Lu, G.3
-
76
-
-
84950127054
-
Andexanet alfa for the reversal of Factor Xa inhibitor activity
-
D.M.SiegalJ.T.CurnutteS.J.Connolly. Andexanet alfa for the reversal of Factor Xa inhibitor activity. N Engl J Med. 2015;373:2413-2424.
-
(2015)
N Engl J Med
, vol.373
, pp. 2413-2424
-
-
Siegal, D.M.1
Curnutte, J.T.2
Connolly, S.J.3
-
77
-
-
84915821873
-
Use of PER977 to reverse the anticoagulant effect of edoxaban
-
J.E.AnsellS.H.BakhruB.E.Laulicht. Use of PER977 to reverse the anticoagulant effect of edoxaban. N Engl J Med. 2014;371:2141-2142.
-
(2014)
N Engl J Med
, vol.371
, pp. 2141-2142
-
-
Ansell, J.E.1
Bakhru, S.H.2
Laulicht, B.E.3
-
78
-
-
84922079881
-
New oral anticoagulants for the treatment of venous thromboembolism: understanding differences and similarities
-
P.P.DobeshJ.FanikosNew oral anticoagulants for the treatment of venous thromboembolism: understanding differences and similarities. Drugs. 2014;74:2015-2032.
-
(2014)
Drugs
, vol.74
, pp. 2015-2032
-
-
Dobesh, P.P.1
Fanikos, J.2
-
79
-
-
84881134435
-
Novel direct-acting anticoagulants for risk reduction in ACS
-
P.P.DobeshJ.H.OestreichNovel direct-acting anticoagulants for risk reduction in ACS. J Pharm Pract. 2013;26:358-366.
-
(2013)
J Pharm Pract
, vol.26
, pp. 358-366
-
-
Dobesh, P.P.1
Oestreich, J.H.2
-
80
-
-
84925624084
-
What is “valvular” atrial fibrillation? A reappraisal
-
R.De CaterinaA.J.Camm. What is “valvular” atrial fibrillation? A reappraisal. Eur Heart J. 2014;35:3328-3335.
-
(2014)
Eur Heart J
, vol.35
, pp. 3328-3335
-
-
De Caterina, R.1
Camm, A.J.2
-
81
-
-
84884512133
-
Dabigatran versus warfarin in patients with mechanical heart valves
-
J.W.EikelboomS.J.ConnollyM.Brueckmann. Dabigatran versus warfarin in patients with mechanical heart valves. N Engl J Med. 2013;369:1206-1214.
-
(2013)
N Engl J Med
, vol.369
, pp. 1206-1214
-
-
Eikelboom, J.W.1
Connolly, S.J.2
Brueckmann, M.3
-
82
-
-
79955432850
-
-
Accessed February 5, 2016
-
European Medicines Agency. Pradaxa: summary of product characteristics. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000829/WC500041059.pdf. Accessed February 5, 2016.
-
Pradaxa: summary of product characteristics
-
-
-
83
-
-
84867577674
-
Dabigatran is effective with a favourable safety profile in normal and overweight patients undergoing major orthopaedic surgery: a pooled analysis
-
B.I.ErikssonO.E.DahlM.Feuring. Dabigatran is effective with a favourable safety profile in normal and overweight patients undergoing major orthopaedic surgery: a pooled analysis. Thromb Res. 2012;130:818-820.
-
(2012)
Thromb Res
, vol.130
, pp. 818-820
-
-
Eriksson, B.I.1
Dahl, O.E.2
Feuring, M.3
-
84
-
-
80055122488
-
Population pharmacokinetic analysis of the oral thrombin inhibitor dabigatran etexilate in patients with non-valvular atrial fibrillation from the RE-LY trial
-
K.H.LiesenfeldT.LehrC.Dansirikul. Population pharmacokinetic analysis of the oral thrombin inhibitor dabigatran etexilate in patients with non-valvular atrial fibrillation from the RE-LY trial. J Thromb Haemost. 2011;9:2168-2175.
-
(2011)
J Thromb Haemost
, vol.9
, pp. 2168-2175
-
-
Liesenfeld, K.H.1
Lehr, T.2
Dansirikul, C.3
-
85
-
-
33846448135
-
Body weight has limited influence on the safety, tolerability, pharmacokinetics, or pharmacodynamics of rivaroxaban (BAY 59-7939) in healthy subjects
-
D.KubitzaM.BeckaM.ZuehlsdorfW.MueckBody weight has limited influence on the safety, tolerability, pharmacokinetics, or pharmacodynamics of rivaroxaban (BAY 59-7939) in healthy subjects. J Clin Pharmacol. 2007;47:218-226.
-
(2007)
J Clin Pharmacol
, vol.47
, pp. 218-226
-
-
Kubitza, D.1
Becka, M.2
Zuehlsdorf, M.3
Mueck, W.4
-
86
-
-
84878921385
-
Effect of extremes of body weight on the pharmacokinetics, pharmacodynamics, safety and tolerability of apixaban in healthy subjects
-
V.V.UpretiJ.WangY.C.Barrett. Effect of extremes of body weight on the pharmacokinetics, pharmacodynamics, safety and tolerability of apixaban in healthy subjects. Br J Clin Pharmacol. 2013;76:908-916.
-
(2013)
Br J Clin Pharmacol
, vol.76
, pp. 908-916
-
-
Upreti, V.V.1
Wang, J.2
Barrett, Y.C.3
-
88
-
-
84882262845
-
Disadvantages of VKA and requirements for novel anticoagulants
-
R.ShameemJ.AnsellDisadvantages of VKA and requirements for novel anticoagulants. Best Pract Res Clin Haematol. 2013;26:103-114.
-
(2013)
Best Pract Res Clin Haematol
, vol.26
, pp. 103-114
-
-
Shameem, R.1
Ansell, J.2
-
89
-
-
84927948517
-
Site-level variation in and practices associated with dabigatran adherence
-
S.ShoreP.M.HoA.Lambert-Kerzner. Site-level variation in and practices associated with dabigatran adherence. JAMA. 2015;313:1443-1450.
-
(2015)
JAMA
, vol.313
, pp. 1443-1450
-
-
Shore, S.1
Ho, P.M.2
Lambert-Kerzner, A.3
-
90
-
-
0038718518
-
Venous thromboembolism and cancer: risks and outcomes
-
A.Y.LeeM.N.LevineVenous thromboembolism and cancer: risks and outcomes. Circulation. 2003;107:I17-I21.
-
(2003)
Circulation
, vol.107
, pp. I17-I21
-
-
Lee, A.Y.1
Levine, M.N.2
-
91
-
-
0037111563
-
Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis
-
P.PrandoniA.W.LensingA.Piccioli. Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis. Blood. 2002;100:3484-3488.
-
(2002)
Blood
, vol.100
, pp. 3484-3488
-
-
Prandoni, P.1
Lensing, A.W.2
Piccioli, A.3
-
92
-
-
84923167380
-
Venous thromboembolism prophylaxis and treatment in patients with cancer: American Society of Clinical Oncology clinical practice guideline update 2014
-
G.H.LymanK.BohlkeA.A.Khorana. Venous thromboembolism prophylaxis and treatment in patients with cancer: American Society of Clinical Oncology clinical practice guideline update 2014. J Clin Oncol. 2015;33:654-656.
-
(2015)
J Clin Oncol
, vol.33
, pp. 654-656
-
-
Lyman, G.H.1
Bohlke, K.2
Khorana, A.A.3
-
93
-
-
84915733549
-
Efficacy and safety of anticoagulant therapy for the treatment of acute cancer-associated thrombosis: a systematic review and meta-analysis
-
M.CarrierC.CameronA.DellucL.CastellucciA.A.KhoranaA.Y.LeeEfficacy and safety of anticoagulant therapy for the treatment of acute cancer-associated thrombosis: a systematic review and meta-analysis. Thromb Res. 2014;134:1214-1219.
-
(2014)
Thromb Res
, vol.134
, pp. 1214-1219
-
-
Carrier, M.1
Cameron, C.2
Delluc, A.3
Castellucci, L.4
Khorana, A.A.5
Lee, A.Y.6
-
94
-
-
84940435041
-
Treatment of venous thromboembolism in patients with cancer: a network meta-analysis comparing efficacy and safety of anticoagulants
-
F.PoschO.KonigsbruggeC.ZielinskiI.PabingerC.AyTreatment of venous thromboembolism in patients with cancer: a network meta-analysis comparing efficacy and safety of anticoagulants. Thromb Res. 2015;136:582-589.
-
(2015)
Thromb Res
, vol.136
, pp. 582-589
-
-
Posch, F.1
Konigsbrugge, O.2
Zielinski, C.3
Pabinger, I.4
Ay, C.5
-
95
-
-
84879575126
-
Role of the pharmacist in achieving performance measures to improve the prevention and treatment of venous thromboembolism
-
P.P.DobeshT.C.TrujilloS.W.FinksRole of the pharmacist in achieving performance measures to improve the prevention and treatment of venous thromboembolism. Pharmacotherapy. 2013;33:650-664.
-
(2013)
Pharmacotherapy
, vol.33
, pp. 650-664
-
-
Dobesh, P.P.1
Trujillo, T.C.2
Finks, S.W.3
-
96
-
-
3543149439
-
Pharmacist-provided anticoagulation management in United States hospitals: death rates, length of stay, Medicare charges, bleeding complications, and transfusions
-
C.A.BondC.L.RaehlPharmacist-provided anticoagulation management in United States hospitals: death rates, length of stay, Medicare charges, bleeding complications, and transfusions. Pharmacotherapy. 2004;24:953-963.
-
(2004)
Pharmacotherapy
, vol.24
, pp. 953-963
-
-
Bond, C.A.1
Raehl, C.L.2
-
97
-
-
70349306707
-
Dabigatran versus warfarin in patients with atrial fibrillation
-
S.J.ConnollyM.D.EzekowitzS.Yusuf. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med. 2009;361:1139-1151.
-
(2009)
N Engl J Med
, vol.361
, pp. 1139-1151
-
-
Connolly, S.J.1
Ezekowitz, M.D.2
Yusuf, S.3
-
98
-
-
77449147211
-
Activities of Memphis-area hospitals to meet National Patient Safety Goals for warfarin therapy
-
S.W.FinksC.S.OliphantA.H.Manguso. Activities of Memphis-area hospitals to meet National Patient Safety Goals for warfarin therapy. Am J Health Syst Pharm. 2009;66:2179-2188.
-
(2009)
Am J Health Syst Pharm
, vol.66
, pp. 2179-2188
-
-
Finks, S.W.1
Oliphant, C.S.2
Manguso, A.H.3
-
99
-
-
84967071454
-
-
Accessed February 5, 2016
-
Institute for Clinical Systems Improvement. Venous thromboembolism prophylaxis. https://www.icsi.org/guidelines__more/catalog_guidelines_and_more/catalog_guidelines/catalog_cardiovascular_guidelines/vte_prophy/. Accessed February 5, 2016.
-
Venous thromboembolism prophylaxis
-
-
-
101
-
-
84941003169
-
Evaluation of prescribing and patient use of target-specific oral anticoagulants in the outpatient setting
-
J.SimonE.HawesZ.DeyoB.Bryant Shilliday. Evaluation of prescribing and patient use of target-specific oral anticoagulants in the outpatient setting. J Clin Pharm Ther. 2015;40:525-530.
-
(2015)
J Clin Pharm Ther
, vol.40
, pp. 525-530
-
-
Simon, J.1
Hawes, E.2
Deyo, Z.3
Bryant Shilliday, B.4
-
102
-
-
84952701083
-
Pharmacokinetics, pharmacodynamics, and safety of apixaban in subjects with end-stage renal disease on hemodialysis
-
X.WangG.TirucheraiT.C.Marbury. Pharmacokinetics, pharmacodynamics, and safety of apixaban in subjects with end-stage renal disease on hemodialysis. J Clin Pharmacol. 2016;56:628-636.
-
(2016)
J Clin Pharmacol
, vol.56
, pp. 628-636
-
-
Wang, X.1
Tirucherai, G.2
Marbury, T.C.3
|