Development and validation of HPLC method for vicenin-1 isolated from fenugreek seeds in rat plasma: application to pharmacokinetic, tissue distribution and excretion studies

Pharmaceutical Biology

Volumn 54, Issue 11, 2016, Pages 2575-2583

  Kandhare, Amit D ^a   Bodhankar, Subhash L ^a   Mohan, Vishwaraman ^b   Thakurdesai, Prasad A ^b  

^a BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

^b Indus Biotech Private Limited   (India)

Author keywords

Bioavailability; elimination; flavonoid glycosides; solid liquid extraction

Indexed keywords

ACETONITRILE; FLAVONOID GLYCOSIDE; UNCLASSIFIED DRUG; VICENIN 1; WATER; APIGENIN; GLUCOSIDE; VICENIN;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG ADRENAL GLAND LEVEL; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG FECES LEVEL; DRUG ISOLATION; DRUG LIVER LEVEL; DRUG LUNG LEVEL; DRUG RAPID TEST; DRUG SMALL INTESTINE LEVEL; DRUG URINE LEVEL; EXTRACTION AND EXTRACTS; FENUGREEK; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PLANT SEED; RAT; SOLID LIQUID EXTRACTION; TIME TO MAXIMUM PLASMA CONCENTRATION; TISSUE DISTRIBUTION; ULTRAVIOLET SPECTROSCOPY; URINARY EXCRETION; VALIDATION PROCESS; ANIMAL; BLOOD; CHEMISTRY; PROCEDURES; TRIGONELLA; VALIDATION STUDY; WISTAR RAT;

ANIMALS; APIGENIN; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUCOSIDES; MALE; RATS; RATS, WISTAR; SEEDS; TISSUE DISTRIBUTION; TRIGONELLA;

EID: 84966746634     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2016.1172245     Document Type: Article

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