메뉴 건너뛰기




Volumn 23, Issue 6, 2016, Pages 1067-1077

Increased Melatonin Signaling Is a Risk Factor for Type 2 Diabetes

(24)  Tuomi, Tiinamaija a,b,c   Nagorny, Cecilia L F d   Singh, Pratibha d   Bennet, Hedvig d   Yu, Qian e   Alenkvist, Ida e   Isomaa, Bo b,c,f   Östman, Bjarne b   Söderström, Johan b,c   Pesonen, Anu Katriina c   Martikainen, Silja c   Räikkönen, Katri c   Forsén, Tom b   Hakaste, Liisa a,b,c   Almgren, Peter c,d   Storm, Petter d   Asplund, Olof d   Shcherbina, Liliya d   Fex, Malin d   Fadista, João d   more..


Author keywords

gene targeting; insulin; islets; recall by genotype; RNA sequencing

Indexed keywords

CYCLIC AMP; GLUCOSE; MELATONIN 1 RECEPTOR; MELATONIN RECEPTOR 1B; UNCLASSIFIED DRUG; INSULIN; MELATONIN; MELATONIN RECEPTOR;

EID: 84966693052     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2016.04.009     Document Type: Article
Times cited : (208)

References (44)
  • 3
    • 84890129569 scopus 로고    scopus 로고
    • Influence of melatonin receptor signalling on parameters involved in blood glucose regulation
    • I. Bazwinsky-Wutschke, L. Bieseke, E. Mühlbauer, and E. Peschke Influence of melatonin receptor signalling on parameters involved in blood glucose regulation J. Pineal Res. 56 2014 82 96
    • (2014) J. Pineal Res. , vol.56 , pp. 82-96
    • Bazwinsky-Wutschke, I.1    Bieseke, L.2    Mühlbauer, E.3    Peschke, E.4
  • 4
    • 0036318476 scopus 로고    scopus 로고
    • Accurate assessment of beta-cell function: The hyperbolic correction
    • R.N. Bergman, M. Ader, K. Huecking, and G. Van Citters Accurate assessment of beta-cell function: the hyperbolic correction Diabetes 51 Suppl 1 2002 S212 S220
    • (2002) Diabetes , vol.51 , pp. S212-S220
    • Bergman, R.N.1    Ader, M.2    Huecking, K.3    Van Citters, G.4
  • 7
    • 31144458770 scopus 로고    scopus 로고
    • Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells
    • O. Dyachok, Y. Isakov, J. Sågetorp, and A. Tengholm Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells Nature 439 2006 349 352
    • (2006) Nature , vol.439 , pp. 349-352
    • Dyachok, O.1    Isakov, Y.2    Sågetorp, J.3    Tengholm, A.4
  • 9
    • 33845934827 scopus 로고    scopus 로고
    • Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from high fat diet-fed C57BL/6J mice
    • M. Fex, M. Dekker Nitert, N. Wierup, C. Ling, F. Sundler, and H. Mulder Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from high fat diet-fed C57BL/6J mice Diabetologia 50 2007 74 83
    • (2007) Diabetologia , vol.50 , pp. 74-83
    • Fex, M.1    Dekker Nitert, M.2    Wierup, N.3    Ling, C.4    Sundler, F.5    Mulder, H.6
  • 10
    • 84948085975 scopus 로고    scopus 로고
    • Common type 2 diabetes risk variant in MTNR1B worsens the deleterious effect of melatonin on glucose tolerance in humans
    • M. Garaulet, P. Gómez-Abellán, P. Rubio-Sastre, J.A. Madrid, R. Saxena, and F.A. Scheer Common type 2 diabetes risk variant in MTNR1B worsens the deleterious effect of melatonin on glucose tolerance in humans Metabolism 64 2015 1650 1657
    • (2015) Metabolism , vol.64 , pp. 1650-1657
    • Garaulet, M.1    Gómez-Abellán, P.2    Rubio-Sastre, P.3    Madrid, J.A.4    Saxena, R.5    Scheer, F.A.6
  • 11
    • 84948984088 scopus 로고    scopus 로고
    • Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
    • K.J. Gaulton, T. Ferreira, Y. Lee, A. Raimondo, R. Mägi, M.E. Reschen, A. Mahajan, A. Locke, N.W. Rayner, N. Robertson, et al. DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci Nat. Genet. 47 2015 1415 1425
    • (2015) Nat. Genet. , vol.47 , pp. 1415-1425
    • Gaulton, K.J.1    Ferreira, T.2    Lee, Y.3    Raimondo, A.4    Mägi, R.5    Reschen, M.E.6    Mahajan, A.7    Locke, A.8    Rayner, N.W.9    Robertson, N.10
  • 14
    • 77955515264 scopus 로고    scopus 로고
    • A family history of diabetes is associated with reduced physical fitness in the Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia study
    • B. Isomaa, B. Forsén, K. Lahti, N. Holmström, J. Wadén, O. Matintupa, P. Almgren, J.G. Eriksson, V. Lyssenko, M.R. Taskinen, and et al. A family history of diabetes is associated with reduced physical fitness in the Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia study Diabetologia 53 2010 1709 1713
    • (2010) Diabetologia , vol.53 , pp. 1709-1713
    • Isomaa, B.1    Forsén, B.2    Lahti, K.3    Holmström, N.4    Wadén, J.5    Matintupa, O.6    Almgren, P.7    Eriksson, J.G.8    Lyssenko, V.9    Taskinen, M.R.10
  • 17
    • 0037077043 scopus 로고    scopus 로고
    • Identification and functional characterization of melatonin Mel 1a receptors in pancreatic beta cells: Potential role in incretin-mediated cell function by sensitization of cAMP signaling
    • D.M. Kemp, M. Ubeda, and J.F. Habener Identification and functional characterization of melatonin Mel 1a receptors in pancreatic beta cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling Mol. Cell. Endocrinol. 191 2002 157 166
    • (2002) Mol. Cell. Endocrinol. , vol.191 , pp. 157-166
    • Kemp, D.M.1    Ubeda, M.2    Habener, J.F.3
  • 23
    • 0032821965 scopus 로고    scopus 로고
    • Insulin sensitivity indices obtained from oral glucose tolerance testing: Comparison with the euglycemic insulin clamp
    • M. Matsuda, and R.A. DeFronzo Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp Diabetes Care 22 1999 1462 1470
    • (1999) Diabetes Care , vol.22 , pp. 1462-1470
    • Matsuda, M.1    DeFronzo, R.A.2
  • 24
    • 80053200210 scopus 로고    scopus 로고
    • Melatonin inhibits insulin secretion in rat insulinoma β-cells (INS-1) heterologously expressing the human melatonin receptor isoform MT2
    • E. Mühlbauer, E. Albrecht, K. Hofmann, I. Bazwinsky-Wutschke, and E. Peschke Melatonin inhibits insulin secretion in rat insulinoma β-cells (INS-1) heterologously expressing the human melatonin receptor isoform MT2 J. Pineal Res. 51 2011 361 372
    • (2011) J. Pineal Res. , vol.51 , pp. 361-372
    • Mühlbauer, E.1    Albrecht, E.2    Hofmann, K.3    Bazwinsky-Wutschke, I.4    Peschke, E.5
  • 25
    • 84859724255 scopus 로고    scopus 로고
    • Melatonin influences insulin secretion primarily via MT(1) receptors in rat insulinoma cells (INS-1) and mouse pancreatic islets
    • E. Mühlbauer, E. Albrecht, I. Bazwinsky-Wutschke, and E. Peschke Melatonin influences insulin secretion primarily via MT(1) receptors in rat insulinoma cells (INS-1) and mouse pancreatic islets J. Pineal Res. 52 2012 446 459
    • (2012) J. Pineal Res. , vol.52 , pp. 446-459
    • Mühlbauer, E.1    Albrecht, E.2    Bazwinsky-Wutschke, I.3    Peschke, E.4
  • 26
    • 67349224047 scopus 로고    scopus 로고
    • Melatonin receptors in pancreatic islets: Good morning to a novel type 2 diabetes gene
    • H. Mulder, C.L.F. Nagorny, V. Lyssenko, and L. Groop Melatonin receptors in pancreatic islets: good morning to a novel type 2 diabetes gene Diabetologia 52 2009 1240 1249
    • (2009) Diabetologia , vol.52 , pp. 1240-1249
    • Mulder, H.1    Nagorny, C.L.F.2    Lyssenko, V.3    Groop, L.4
  • 28
    • 33645098511 scopus 로고    scopus 로고
    • Parallel signaling pathways of melatonin in the pancreatic beta-cell
    • E. Peschke, A.G. Bach, and E. Mühlbauer Parallel signaling pathways of melatonin in the pancreatic beta-cell J. Pineal Res. 40 2006 184 191
    • (2006) J. Pineal Res. , vol.40 , pp. 184-191
    • Peschke, E.1    Bach, A.G.2    Mühlbauer, E.3
  • 29
    • 84934268769 scopus 로고    scopus 로고
    • Experimental and clinical aspects of melatonin and clock genes in diabetes
    • E. Peschke, I. Bähr, and E. Mühlbauer Experimental and clinical aspects of melatonin and clock genes in diabetes J. Pineal Res. 59 2015 1 23
    • (2015) J. Pineal Res. , vol.59 , pp. 1-23
    • Peschke, E.1    Bähr, I.2    Mühlbauer, E.3
  • 30
    • 84925347828 scopus 로고    scopus 로고
    • Genetics of type 2 diabetes-pitfalls and possibilities
    • R.B. Prasad, and L. Groop Genetics of type 2 diabetes-pitfalls and possibilities Genes (Basel) 6 2015 87 123
    • (2015) Genes (Basel) , vol.6 , pp. 87-123
    • Prasad, R.B.1    Groop, L.2
  • 34
    • 84939981613 scopus 로고    scopus 로고
    • Season-dependent associations of circadian rhythm-regulating loci (CRY1, CRY2 and MTNR1B) and glucose homeostasis: The GLACIER Study
    • F. Renström, R.W. Koivula, T.V. Varga, G. Hallmans, H. Mulder, J.C. Florez, F.B. Hu, and P.W. Franks Season-dependent associations of circadian rhythm-regulating loci (CRY1, CRY2 and MTNR1B) and glucose homeostasis: the GLACIER Study Diabetologia 58 2015 997 1005
    • (2015) Diabetologia , vol.58 , pp. 997-1005
    • Renström, F.1    Koivula, R.W.2    Varga, T.V.3    Hallmans, G.4    Mulder, H.5    Florez, J.C.6    Hu, F.B.7    Franks, P.W.8
  • 35
    • 64149094603 scopus 로고    scopus 로고
    • A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals
    • T. Rönn, J. Wen, Z. Yang, B. Lu, Y. Du, L. Groop, R. Hu, and C. Ling A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals Diabetologia 52 2009 830 833
    • (2009) Diabetologia , vol.52 , pp. 830-833
    • Rönn, T.1    Wen, J.2    Yang, Z.3    Lu, B.4    Du, Y.5    Groop, L.6    Hu, R.7    Ling, C.8
  • 36
    • 84907930175 scopus 로고    scopus 로고
    • Acute melatonin administration in humans impairs glucose tolerance in both the morning and evening
    • P. Rubio-Sastre, F.A. Scheer, P. Gómez-Abellán, J.A. Madrid, and M. Garaulet Acute melatonin administration in humans impairs glucose tolerance in both the morning and evening Sleep 37 2014 1715 1719
    • (2014) Sleep , vol.37 , pp. 1715-1719
    • Rubio-Sastre, P.1    Scheer, F.A.2    Gómez-Abellán, P.3    Madrid, J.A.4    Garaulet, M.5
  • 37
    • 63149163425 scopus 로고    scopus 로고
    • Adverse metabolic and cardiovascular consequences of circadian misalignment
    • F.A. Scheer, M.F. Hilton, C.S. Mantzoros, and S.A. Shea Adverse metabolic and cardiovascular consequences of circadian misalignment Proc. Natl. Acad. Sci. USA 106 2009 4453 4458
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 4453-4458
    • Scheer, F.A.1    Hilton, M.F.2    Mantzoros, C.S.3    Shea, S.A.4
  • 38
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • J.E. Shaw, R.A. Sicree, and P.Z. Zimmet Global estimates of the prevalence of diabetes for 2010 and 2030 Diabetes Res. Clin. Pract. 87 2010 4 14
    • (2010) Diabetes Res. Clin. Pract. , vol.87 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 41
    • 79959390543 scopus 로고    scopus 로고
    • Glucose- and hormone-induced cAMP oscillations in α- And β-cells within intact pancreatic islets
    • G. Tian, S. Sandler, E. Gylfe, and A. Tengholm Glucose- and hormone-induced cAMP oscillations in α- and β-cells within intact pancreatic islets Diabetes 60 2011 1535 1543
    • (2011) Diabetes , vol.60 , pp. 1535-1543
    • Tian, G.1    Sandler, S.2    Gylfe, E.3    Tengholm, A.4
  • 42
    • 84874503583 scopus 로고    scopus 로고
    • Genome wide association studies for diabetes: Perspective on results and challenges
    • J.M. Torres, N.J. Cox, and L.H. Philipson Genome wide association studies for diabetes: perspective on results and challenges Pediatr. Diabetes 14 2013 90 96
    • (2013) Pediatr. Diabetes , vol.14 , pp. 90-96
    • Torres, J.M.1    Cox, N.J.2    Philipson, L.H.3
  • 44
    • 0035991404 scopus 로고    scopus 로고
    • Mammalian melatonin receptors: Molecular biology and signal transduction
    • C. von Gall, J.H. Stehle, and D.R. Weaver Mammalian melatonin receptors: molecular biology and signal transduction Cell Tissue Res. 309 2002 151 162
    • (2002) Cell Tissue Res. , vol.309 , pp. 151-162
    • Von Gall, C.1    Stehle, J.H.2    Weaver, D.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.