Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases

Molecular Cell

Volumn 62, Issue 3, 2016, Pages 397-408

  Hamill, Stephanie ^a   Lou, Hua Jane ^a   Turk, Benjamin E ^a,b   Boggon, Titus J ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ACTIN DEPOLYMERIZING FACTOR; COFILIN 1; LIM KINASE; CFL1 PROTEIN, HUMAN; COF1 PROTEIN, S CEREVISIAE; LIMK1 PROTEIN, HUMAN; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE PROTEIN; SERINE;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; CYTOSKELETON; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; KINASE ASSAY; MAMMAL CELL; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; NONHUMAN; PROTEIN PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE; YEAST CELL; BINDING SITE; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; METABOLISM; MOLECULAR MODEL; MUTATION; PHOSPHORYLATION; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CATALYTIC DOMAIN; COFILIN 1; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HUMANS; LIM KINASES; MODELS, MOLECULAR; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SERINE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TRANSFECTION;

EID: 84966659416     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.04.001     Document Type: Article

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