메뉴 건너뛰기




Volumn 35, Issue 6, 2014, Pages 1352-1361

Interleukin-22 promotes epithelial cell transformation and breast tumorigenesis via MAP3K8 activation

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; INTERLEUKIN 22; INTERLEUKIN 22 RECEPTOR 1; INTERLEUKIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; PEPTIDYLPROLYL ISOMERASE PIN1; RECOMBINANT CYTOKINE; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE 1; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TKI; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; MAP3K8 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; NIMA INTERACTING PEPTIDYLPROLYL ISOMERASE; NIMA-INTERACTING PEPTIDYLPROLYL ISOMERASE; ONCOPROTEIN; PEPTIDYLPROLYL ISOMERASE; PROTEIN C JUN;

EID: 84905381855     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgu044     Document Type: Article
Times cited : (89)

References (50)
  • 1
    • 79955030498 scopus 로고    scopus 로고
    • Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22
    • Sonnenberg, G.F. et al. (2011) Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22. Nat. Immunol., 12, 383-390.
    • (2011) Nat. Immunol , vol.12 , pp. 383-390
    • Sonnenberg, G.F.1
  • 2
    • 67651154105 scopus 로고    scopus 로고
    • Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
    • Duhen, T. et al. (2009) Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat. Immunol., 10, 857-863.
    • (2009) Nat. Immunol , vol.10 , pp. 857-863
    • Duhen, T.1
  • 3
    • 67651171182 scopus 로고    scopus 로고
    • Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells
    • Trifari, S. et al. (2009) Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells. Nat. Immunol., 10, 864-871.
    • (2009) Nat. Immunol , vol.10 , pp. 864-871
    • Trifari, S.1
  • 4
    • 2342659126 scopus 로고    scopus 로고
    • Interleukin-10 and related cytokines and receptors
    • Pestka, S. et al. (2004) Interleukin-10 and related cytokines and receptors. Annu. Rev. Immunol., 22, 929-979.
    • (2004) Annu. Rev. Immunol , vol.22 , pp. 929-979
    • Pestka, S.1
  • 5
    • 0035951795 scopus 로고    scopus 로고
    • Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes
    • Kotenko, S.V. et al. (2001) Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes. J. Biol. Chem., 276, 2725-2732.
    • (2001) J. Biol. Chem , vol.276 , pp. 2725-2732
    • Kotenko, S.V.1
  • 6
    • 11144354300 scopus 로고    scopus 로고
    • Temporal associations between interleukin 22 and the extracellular domains of IL-22R and IL-10R2
    • Li, J. et al. (2004) Temporal associations between interleukin 22 and the extracellular domains of IL-22R and IL-10R2. Int. Immunopharmacol., 4, 693-708.
    • (2004) Int. Immunopharmacol , vol.4 , pp. 693-708
    • Li, J.1
  • 7
    • 80052023399 scopus 로고    scopus 로고
    • Interleukin-22 promotes human hepatocellular carcinoma by activation of STAT3
    • Jiang, R. et al. (2011) Interleukin-22 promotes human hepatocellular carcinoma by activation of STAT3. Hepatology, 54, 900-909.
    • (2011) Hepatology , vol.54 , pp. 900-909
    • Jiang, R.1
  • 8
    • 0034613201 scopus 로고    scopus 로고
    • Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R
    • Xie, M.H. et al. (2000) Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J. Biol. Chem., 275, 31335-31339.
    • (2000) J. Biol. Chem , vol.275 , pp. 31335-31339
    • Xie, M.H.1
  • 9
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov, S.I. et al. (2010) Immunity, inflammation, and cancer. Cell, 140, 883-899.
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1
  • 10
    • 0029972261 scopus 로고    scopus 로고
    • Involvement of the Tpl-2/cot oncogene in MMTV tumorigenesis
    • Erny, K.M. et al. (1996) Involvement of the Tpl-2/cot oncogene in MMTV tumorigenesis. Oncogene, 13, 2015-2020.
    • (1996) Oncogene , vol.13 , pp. 2015-2020
    • Erny, K.M.1
  • 11
    • 0030902506 scopus 로고    scopus 로고
    • Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation
    • Ceci, J.D. et al. (1997) Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation. Genes Dev., 11, 688-700.
    • (1997) Genes Dev , vol.11 , pp. 688-700
    • Ceci, J.D.1
  • 12
    • 0030059508 scopus 로고    scopus 로고
    • Activation of MEK-1 and SEK-1 by Tpl-2 protooncoprotein, a novel MAP kinase kinase kinase
    • Salmeron, A. et al. (1996) Activation of MEK-1 and SEK-1 by Tpl-2 protooncoprotein, a novel MAP kinase kinase kinase. EMBO J., 15, 817-826.
    • (1996) EMBO J , vol.15 , pp. 817-826
    • Salmeron, A.1
  • 13
    • 0033970230 scopus 로고    scopus 로고
    • Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation
    • Chiariello, M. et al. (2000) Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation. Mol. Cell. Biol., 20, 1747-1758.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 1747-1758
    • Chiariello, M.1
  • 14
    • 0027937795 scopus 로고
    • Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase
    • Patriotis, C. et al. (1994) Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase. Proc. Natl. Acad. Sci. U. S. A., 91, 9755-9759.
    • (1994) Proc. Natl. Acad. Sci. U. S. A , vol.91 , pp. 9755-9759
    • Patriotis, C.1
  • 15
    • 0032584102 scopus 로고    scopus 로고
    • The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines
    • Tsatsanis, C. et al. (1998) The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines. Proc. Natl. Acad. Sci. U. S. A., 95, 3827-3832.
    • (1998) Proc. Natl. Acad. Sci. U. S. A , vol.95 , pp. 3827-3832
    • Tsatsanis, C.1
  • 16
    • 0031571329 scopus 로고    scopus 로고
    • Cot kinase regulation of IL-2 production in Jurkat T cells
    • Ballester, A. et al. (1997) Cot kinase regulation of IL-2 production in Jurkat T cells. J. Immunol., 159, 1613-1618.
    • (1997) J. Immunol , vol.159 , pp. 1613-1618
    • Ballester, A.1
  • 17
    • 9644301015 scopus 로고    scopus 로고
    • A serine/threonine kinase, Cot/Tpl2, modulates bacterial DNA-induced IL-12 production and Th cell differentiation
    • Sugimoto, K. et al. (2004) A serine/threonine kinase, Cot/Tpl2, modulates bacterial DNA-induced IL-12 production and Th cell differentiation. J. Clin. Invest., 114, 857-866.
    • (2004) J. Clin. Invest , vol.114 , pp. 857-866
    • Sugimoto, K.1
  • 18
    • 34247490735 scopus 로고    scopus 로고
    • PIN1, the cell cycle and cancer
    • Yeh, E.S. et al. (2007) PIN1, the cell cycle and cancer. Nat. Rev. Cancer, 7, 381-388.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 381-388
    • Yeh, E.S.1
  • 19
    • 33746042979 scopus 로고    scopus 로고
    • Structure-function-folding relationship in a WW domain
    • Jäger, M. et al. (2006) Structure-function-folding relationship in a WW domain. Proc. Natl. Acad. Sci. U. S. A., 103, 10648-10653.
    • (2006) Proc. Natl. Acad. Sci. U. S. A , vol.103 , pp. 10648-10653
    • Jäger, M.1
  • 20
    • 0033629682 scopus 로고    scopus 로고
    • Phosphorylation-dependent prolyl isomerization: a novel cell cycle regulatory mechanism
    • Lu, K.P. (2000) Phosphorylation-dependent prolyl isomerization: a novel cell cycle regulatory mechanism. Prog. Cell Cycle Res., 4, 83-96.
    • (2000) Prog. Cell Cycle Res , vol.4 , pp. 83-96
    • Lu, K.P.1
  • 21
    • 18644384688 scopus 로고    scopus 로고
    • The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response
    • Zheng, H. et al. (2002) The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response. Nature, 419, 849-853.
    • (2002) Nature , vol.419 , pp. 849-853
    • Zheng, H.1
  • 22
    • 34247464252 scopus 로고    scopus 로고
    • Prolyl isomerase Pin1 expression predicts prognosis in patients with esophageal squamous cell carcinoma and correlates with cyclinD1 expression
    • Fukuchi, M. et al. (2006) Prolyl isomerase Pin1 expression predicts prognosis in patients with esophageal squamous cell carcinoma and correlates with cyclinD1 expression. Int. J. Oncol., 29, 329-334.
    • (2006) Int. J. Oncol , vol.29 , pp. 329-334
    • Fukuchi, M.1
  • 23
    • 0035796405 scopus 로고    scopus 로고
    • Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1
    • Wulf, G.M. et al. (2001) Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1. EMBO J., 20, 3459-3472.
    • (2001) EMBO J , vol.20 , pp. 3459-3472
    • Wulf, G.M.1
  • 24
    • 77949742297 scopus 로고    scopus 로고
    • The prolyl isomerase Pin1 enhances HER-2 expression and cellular transformation via its interaction with mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1
    • Khanal, P. et al. (2010) The prolyl isomerase Pin1 enhances HER-2 expression and cellular transformation via its interaction with mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1. Mol. Cancer Ther., 9, 606-616.
    • (2010) Mol. Cancer Ther , vol.9 , pp. 606-616
    • Khanal, P.1
  • 25
    • 0347955360 scopus 로고    scopus 로고
    • Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA
    • Ryo, A. et al. (2003) Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. Mol. Cell, 12, 1413-1426.
    • (2003) Mol. Cell , vol.12 , pp. 1413-1426
    • Ryo, A.1
  • 26
    • 36849062265 scopus 로고    scopus 로고
    • Pin1 is required for the Ser727 phosphorylationdependent Stat3 activity
    • Lufei, C. et al. (2007) Pin1 is required for the Ser727 phosphorylationdependent Stat3 activity. Oncogene, 26, 7656-7664.
    • (2007) Oncogene , vol.26 , pp. 7656-7664
    • Lufei, C.1
  • 27
    • 10344258041 scopus 로고    scopus 로고
    • Targeting the mitogen-activated protein kinase cascade to treat cancer
    • Sebolt-Leopold, J.S. et al. (2004) Targeting the mitogen-activated protein kinase cascade to treat cancer. Nat. Rev. Cancer, 4, 937-947.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 937-947
    • Sebolt-Leopold, J.S.1
  • 28
    • 21244463215 scopus 로고    scopus 로고
    • Tpl2/cot signals activate ERK, JNK, and NF-kappaB in a cell-type and stimulus-specific manner
    • Das, S. et al. (2005) Tpl2/cot signals activate ERK, JNK, and NF-kappaB in a cell-type and stimulus-specific manner. J. Biol. Chem., 280, 23748-23757.
    • (2005) J. Biol. Chem , vol.280 , pp. 23748-23757
    • Das, S.1
  • 29
    • 2342462460 scopus 로고    scopus 로고
    • Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation
    • Radaeva, S. et al. (2004) Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation. Hepatology, 39, 1332-1342.
    • (2004) Hepatology , vol.39 , pp. 1332-1342
    • Radaeva, S.1
  • 30
    • 77954951053 scopus 로고    scopus 로고
    • The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer
    • Namgoong, G.M. et al. (2010) The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer. J. Biol. Chem., 285, 23829-23841.
    • (2010) J. Biol. Chem , vol.285 , pp. 23829-23841
    • Namgoong, G.M.1
  • 31
    • 0242691046 scopus 로고    scopus 로고
    • AP-1: a double-edged sword in tumorigenesis
    • Eferl, R. et al. (2003) AP-1: a double-edged sword in tumorigenesis. Nat. Rev. Cancer, 3, 859-868.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 859-868
    • Eferl, R.1
  • 32
    • 0029032249 scopus 로고
    • The regulation of AP-1 activity by mitogen-activated protein kinases
    • Karin, M. (1995) The regulation of AP-1 activity by mitogen-activated protein kinases. J. Biol. Chem., 270, 16483-16486.
    • (1995) J. Biol. Chem , vol.270 , pp. 16483-16486
    • Karin, M.1
  • 33
    • 33646848776 scopus 로고    scopus 로고
    • A novel cis-acting element in Her2 promoter regulated by Stat3 in mammary cancer cells
    • Qian, L. et al. (2006) A novel cis-acting element in Her2 promoter regulated by Stat3 in mammary cancer cells. Biochem. Biophys. Res. Commun., 345, 660-668.
    • (2006) Biochem. Biophys. Res. Commun , vol.345 , pp. 660-668
    • Qian, L.1
  • 34
    • 78650034777 scopus 로고    scopus 로고
    • Towards a knowledge-based Human Protein Atlas
    • Uhlen, M. et al. (2010) Towards a knowledge-based Human Protein Atlas. Nat. Biotechnol., 28, 1248-1250.
    • (2010) Nat. Biotechnol , vol.28 , pp. 1248-1250
    • Uhlen, M.1
  • 35
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • Zou, W. (2005) Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat. Rev. Cancer, 5, 263-274.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 263-274
    • Zou, W.1
  • 36
    • 8144228952 scopus 로고    scopus 로고
    • Friends or foes-bipolar effects of the tumour stroma in cancer
    • Mueller, M.M. et al. (2004) Friends or foes-bipolar effects of the tumour stroma in cancer. Nat. Rev. Cancer, 4, 839-849.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 839-849
    • Mueller, M.M.1
  • 37
    • 20444412646 scopus 로고    scopus 로고
    • Therapeutic targeting of the tumor microenvironment
    • Joyce, J.A. (2005) Therapeutic targeting of the tumor microenvironment. Cancer Cell, 7, 513-520.
    • (2005) Cancer Cell , vol.7 , pp. 513-520
    • Joyce, J.A.1
  • 38
    • 27644575157 scopus 로고    scopus 로고
    • Coordinating ERK/MAPK signalling through scaffolds and inhibitors
    • Kolch, W. (2005) Coordinating ERK/MAPK signalling through scaffolds and inhibitors. Nat. Rev. Mol. Cell Biol., 6, 827-837.
    • (2005) Nat. Rev. Mol. Cell Biol , vol.6 , pp. 827-837
    • Kolch, W.1
  • 39
    • 30944447568 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions
    • Yoon, S. et al. (2006) The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors, 24, 21-44.
    • (2006) Growth Factors , vol.24 , pp. 21-44
    • Yoon, S.1
  • 40
    • 21644440921 scopus 로고    scopus 로고
    • Recent progress in targeting the Raf/MEK/ERK pathway with inhibitors in cancer drug discovery
    • Thompson, N. et al. (2005) Recent progress in targeting the Raf/MEK/ERK pathway with inhibitors in cancer drug discovery. Curr. Opin. Pharmacol., 5, 350-356.
    • (2005) Curr. Opin. Pharmacol , vol.5 , pp. 350-356
    • Thompson, N.1
  • 41
    • 0037057521 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion
    • Harmey, J.H. et al. (2002) Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion. Int. J. Cancer, 101, 415-422.
    • (2002) Int. J. Cancer , vol.101 , pp. 415-422
    • Harmey, J.H.1
  • 42
    • 0032983865 scopus 로고    scopus 로고
    • Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis
    • Moore, R.J. et al. (1999) Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis. Nat. Med., 5, 828-831.
    • (1999) Nat. Med , vol.5 , pp. 828-831
    • Moore, R.J.1
  • 43
    • 0026022698 scopus 로고
    • Role of endogenous tumor necrosis factor alpha and interleukin 1 for experimental tumor growth and the development of cancer cachexia
    • Gelin, J. et al. (1991) Role of endogenous tumor necrosis factor alpha and interleukin 1 for experimental tumor growth and the development of cancer cachexia. Cancer Res., 51, 415-421.
    • (1991) Cancer Res , vol.51 , pp. 415-421
    • Gelin, J.1
  • 44
    • 17744371331 scopus 로고    scopus 로고
    • TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway
    • Dumitru, C.D. et al. (2000) TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway. Cell, 103, 1071-1083.
    • (2000) Cell , vol.103 , pp. 1071-1083
    • Dumitru, C.D.1
  • 45
    • 76249111625 scopus 로고    scopus 로고
    • Tumor progression locus 2 (Map3k8) is critical for host defense against Listeria monocytogenes and IL-1 beta production
    • Mielke, L.A. et al. (2009) Tumor progression locus 2 (Map3k8) is critical for host defense against Listeria monocytogenes and IL-1 beta production. J. Immunol., 183, 7984-7993.
    • (2009) J. Immunol , vol.183 , pp. 7984-7993
    • Mielke, L.A.1
  • 46
    • 0033517331 scopus 로고    scopus 로고
    • Overexpression of the Tpl-2/Cot oncogene in human breast cancer
    • Sourvinos, G. et al. (1999) Overexpression of the Tpl-2/Cot oncogene in human breast cancer. Oncogene, 18, 4968-4973.
    • (1999) Oncogene , vol.18 , pp. 4968-4973
    • Sourvinos, G.1
  • 47
    • 38049113253 scopus 로고    scopus 로고
    • Cot, a novel kinase of histone H3, induces cellular transformation through up-regulation of c-fos transcriptional activity
    • Choi, H.S. et al. (2008) Cot, a novel kinase of histone H3, induces cellular transformation through up-regulation of c-fos transcriptional activity. FASEB J., 22, 113-126.
    • (2008) FASEB J , vol.22 , pp. 113-126
    • Choi, H.S.1
  • 48
    • 84873529688 scopus 로고    scopus 로고
    • Interleukin-17 induces AP-1 activity and cellular transformation via upregulation of tumor progression locus 2 activity
    • Kim, G. et al. (2013) Interleukin-17 induces AP-1 activity and cellular transformation via upregulation of tumor progression locus 2 activity. Carcinogenesis, 34, 341-350.
    • (2013) Carcinogenesis , vol.34 , pp. 341-350
    • Kim, G.1
  • 49
    • 0036535975 scopus 로고    scopus 로고
    • Pinning down proline-directed phosphorylation signaling
    • Lu, K.P. et al. (2002) Pinning down proline-directed phosphorylation signaling. Trends Cell Biol., 12, 164-172.
    • (2002) Trends Cell Biol , vol.12 , pp. 164-172
    • Lu, K.P.1
  • 50
    • 0037351048 scopus 로고    scopus 로고
    • Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer
    • Ryo, A. et al. (2003) Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer. J. Cell Sci., 116(Pt 5), 773-783.
    • (2003) J. Cell Sci , vol.116 , pp. 773-783
    • Ryo, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.