Identification of benzothiazole derivatives and polycyclic aromatic hydrocarbons as aryl hydrocarbon receptor agonists present in tire extracts

Environmental Toxicology and Chemistry

Volumn 30, Issue 8, 2011, Pages 1915-1925

  He, Guochun ^a   Zhao, Bin ^a,b   Denison, Michael S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b RESEARCH CENTER FOR ECO ENVIRONMENTAL SCIENCES   (China)

Author keywords

Ah receptor; Benzothiazoles; CALUX; Tires; Toxicant identification evaluation

Indexed keywords

2-MERCAPTOBENZOTHIAZOLE; ACTIVE CHEMICALS; AGONIST ACTIVITY; AH RECEPTOR; AQUATIC ORGANISMS; ARYL HYDROCARBON RECEPTOR; BENZOTHIAZOLE DERIVATIVES; BENZOTHIAZOLES; BIOLOGICAL EFFECTS; CALUX; COMPLEX MIXTURE; DIRECT INTERACTIONS; DNA BINDING; LEACHATES; LUCIFERASE GENES; SIGNALING PATHWAYS; TIRE MATERIAL; TOXICANT IDENTIFICATION EVALUATION;

AROMATIC COMPOUNDS; BIOASSAY; BIOLOGICAL MATERIALS; CHEMICALS; COMPLEXATION; GENE EXPRESSION; HYDROCARBONS; LEACHING; POLYCYCLIC AROMATIC HYDROCARBONS; SIGNALING;

TIRES;

2 MERCAPTOBENZOTHIAZOLE; 2 METHYLTHIOBENZOTHIAZOLE; AROMATIC HYDROCARBON RECEPTOR; BENZOTHIAZOLE DERIVATIVE; LUCIFERASE; POLYCYCLIC AROMATIC HYDROCARBON; UNCLASSIFIED DRUG;

AQUATIC ORGANISM; BIOASSAY; FISH; GENE EXPRESSION; GENETIC ANALYSIS; IDENTIFICATION METHOD; LEACHATE; METABOLISM; ORGANIC COMPOUND; POLLUTION EFFECT; TIRE; TOXICOLOGY;

ANIMAL CELL; ARTICLE; CHEMICAL ANALYSIS; DNA BINDING; GENE EXPRESSION; LEACHING; MOTOR VEHICLE TIRE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; BENZOTHIAZOLES; BIOLOGICAL ASSAY; CELL LINE; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION; LUCIFERASES; MICE; MOLECULAR STRUCTURE; POLYCYCLIC HYDROCARBONS, AROMATIC; RECEPTORS, ARYL HYDROCARBON; RUBBER;

EID: 79960085652     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1002/etc.581     Document Type: Article

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