Oligodendrogliopathy in multiple sclerosis: Low glycolytic metabolic rate promotes oligodendrocyte survival

Journal of Neuroscience

Volumn 36, Issue 17, 2016, Pages 4698-4707

  Rone, Malena B ^a   Cui, Qiao Ling ^a   Fang, Jun ^b   Wang, Li Chun ^b   Zhang, Ji ^a,c   Khan, Damla ^a   Bedard, Melissa ^a   Almazan, Guillermina ^b   Ludwin, Samuel K ^a   Jones, Russel ^b   Kennedy, Timothy E ^a   Antel, Jack P ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Aerobic glycolysis; Metabolic stress; Multiple sclerosis; Oligodendrocytes; Oligodendrogliopathy

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; GLYCOLYTIC ENZYME; MYELIN;

ADULT; ANIMAL CELL; ARTICLE; BIOENERGY; BRAIN HYPOXIA; CELL SURVIVAL; CONTROLLED STUDY; GLYCOLYSIS; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; METABOLIC FLUX ANALYSIS; METABOLIC RATE; METABOLIC STRESS; MICROGLIA; MULTIPLE SCLEROSIS; NEUROLOGIC DISEASE; NONHUMAN; OLIGODENDROCYTE PRECURSOR CELL; OLIGODENDROGLIA; OLIGODENDROGLIOPATHY; PRIORITY JOURNAL; RAT; ANIMAL; BRAIN; CELL CULTURE; CELL DEATH; DEMYELINATING DISEASE; METABOLISM; MYELIN SHEATH; PATHOLOGY; SPRAGUE DAWLEY RAT; STEM CELL;

ANIMALS; BRAIN; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; DEMYELINATING DISEASES; GLYCOLYSIS; HUMANS; MULTIPLE SCLEROSIS; MYELIN SHEATH; OLIGODENDROGLIA; RATS; RATS, SPRAGUE-DAWLEY; STEM CELLS;

EID: 84966489904     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4077-15.2016     Document Type: Article

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