메뉴 건너뛰기




Volumn 26, Issue 6, 2016, Pages 703-717

Polymeric networks for controlled release of drugs: a patent review

Author keywords

Controlled drug delivery; crosslinking; drug delivery systems; hydrogels; interpenetrating polymer networks; patents; polymer network; stimulus responsive drug delivery systems

Indexed keywords

POLYMER; DELAYED RELEASE FORMULATION; DRUG; NANOPARTICLE;

EID: 84966472173     PISSN: 13543776     EISSN: 17447674     Source Type: Journal    
DOI: 10.1080/13543776.2016.1178720     Document Type: Review
Times cited : (6)

References (95)
  • 1
    • 79952290746 scopus 로고    scopus 로고
    • Polymers in drug delivery-state of the art and future trends
    • S.Grund, M.Bauer, D.Fischer Polymers in drug delivery-state of the art and future trends. Adv Engineer Mater. 2011;13:B61–B87.
    • (2011) Adv Engineer Mater , vol.13 , pp. B61-B87
    • Grund, S.1    Bauer, M.2    Fischer, D.3
  • 2
    • 85027424787 scopus 로고    scopus 로고
    • Significance of polymers in drug delivery system
    • P.Agrawal. Significance of polymers in drug delivery system. J Pharmacovigil. 2015;3:e127.
    • (2015) J Pharmacovigil , vol.3 , pp. e127
    • Agrawal, P.1
  • 3
    • 85017473422 scopus 로고    scopus 로고
    • IUPAC, Glossary of basic terms in polymer science
    • (Def. 1.58)
    • A.D.Jenkins, P.Kratochvíl, R.F.T.Stepto, et al. IUPAC, Glossary of basic terms in polymer science. Pure Appl Chem. 1996;68:2287. (Def. 1.58)
    • (1996) Pure Appl Chem , vol.68 , pp. 2287
    • Jenkins, A.D.1    Kratochvíl, P.2    Stepto, R.F.T.3
  • 4
    • 84862557140 scopus 로고    scopus 로고
    • Water soluble polymers as proton exchange membranes for fuel cells
    • Y.-S.Ye, J.Rick, B.-J.Hwang. Water soluble polymers as proton exchange membranes for fuel cells. Polym. 2012;4:913–963.
    • (2012) Polym , vol.4 , pp. 913-963
    • Ye, Y.-S.1    Rick, J.2    Hwang, B.-J.3
  • 5
    • 84865745216 scopus 로고    scopus 로고
    • Highly stretchable and tough hydrogels
    • J.-Y.Sun, X.Zhao, W.R.K.Illeperuma, et al. Highly stretchable and tough hydrogels. Nature. 2012;489:133–136.
    • (2012) Nature , vol.489 , pp. 133-136
    • Sun, J.-Y.1    Zhao, X.2    Illeperuma, W.R.K.3
  • 6
    • 77955653108 scopus 로고    scopus 로고
    • Self-assembled hydrogel nanoparticles for drug delivery applications
    • C.Gonçalves, P.Pereira, M.Gama. Self-assembled hydrogel nanoparticles for drug delivery applications. Materials. 2010;3:1420–1460.
    • (2010) Materials , vol.3 , pp. 1420-1460
    • Gonçalves, C.1    Pereira, P.2    Gama, M.3
  • 9
    • 0009603748 scopus 로고    scopus 로고
    • IUPAC, Source-based nomenclature for non-linear macromolecules and macromolecular assemblies
    • A.D.Jenkins, J.Kahovec, P.Kratochvíl, et al. IUPAC, Source-based nomenclature for non-linear macromolecules and macromolecular assemblies. Pure Appl Chem. 1997;69:2511.
    • (1997) Pure Appl Chem , vol.69 , pp. 2511
    • Jenkins, A.D.1    Kahovec, J.2    Kratochvíl, P.3
  • 11
    • 84923151514 scopus 로고    scopus 로고
    • Hydrogel: Preparation, characterization, and applications: A review
    • E.M.Ahmed. Hydrogel: preparation, characterization, and applications: A review. J Adv Res. 2015;6:105–121.
    • (2015) J Adv Res , vol.6 , pp. 105-121
    • Ahmed, E.M.1
  • 12
    • 78651379819 scopus 로고    scopus 로고
    • Polymers for drug delivery systems
    • •• Excellent insight into intelligent polymeric drug delivery systems
    • W.B.Liechty, D.R.Kryscio, B.V.Slaughter, et al. Polymers for drug delivery systems. Annu Rev Chem Biomol Eng. 2010;1:149–173.•• Excellent insight into intelligent polymeric drug delivery systems.
    • (2010) Annu Rev Chem Biomol Eng , vol.1 , pp. 149-173
    • Liechty, W.B.1    Kryscio, D.R.2    Slaughter, B.V.3
  • 13
    • 84927667186 scopus 로고    scopus 로고
    • A novel crosslinked hyaluronic acid nanogel for drug delivery
    • S.S.Pedrosa, C.Gonçalves, L.David, et al. A novel crosslinked hyaluronic acid nanogel for drug delivery. Macromol Biosci. 2014;14:1556–1568.
    • (2014) Macromol Biosci , vol.14 , pp. 1556-1568
    • Pedrosa, S.S.1    Gonçalves, C.2    David, L.3
  • 14
    • 78650121491 scopus 로고    scopus 로고
    • Self-cross-linked polymer nanogels: A versatile nanoscopic drug delivery platform
    • J.H.Ryu, R.T.Chacko, S.Jiwpanich, et al. Self-cross-linked polymer nanogels: a versatile nanoscopic drug delivery platform. J Am Chem Soc. 2010;8(132):17227–17235.
    • (2010) J Am Chem Soc , vol.8 , Issue.132 , pp. 17227-17235
    • Ryu, J.H.1    Chacko, R.T.2    Jiwpanich, S.3
  • 15
    • 84919935106 scopus 로고    scopus 로고
    • Curcumin encapsulated pH sensitive gelatin based interpenetrating polymeric network nanogels for anti cancer drug delivery
    • K.Madhusudana Rao, K.Rao, G.Ramanjaneyulu, et al. Curcumin encapsulated pH sensitive gelatin based interpenetrating polymeric network nanogels for anti cancer drug delivery. Int J Pharm. 2015;478:788–795.
    • (2015) Int J Pharm , vol.478 , pp. 788-795
    • Madhusudana Rao, K.1    Rao, K.2    Ramanjaneyulu, G.3
  • 16
    • 84891601173 scopus 로고    scopus 로고
    • Cytocompatible injectable carboxymethyl chitosan/N-isopropylacrylamide hydrogels for localized drug delivery
    • W.L.Zhang, B.Guo, X.P.Ma. Cytocompatible injectable carboxymethyl chitosan/N-isopropylacrylamide hydrogels for localized drug delivery. Carbohydr Polym. 2014;103:110–118.
    • (2014) Carbohydr Polym , vol.103 , pp. 110-118
    • Zhang, W.L.1    Guo, B.2    Ma, X.P.3
  • 17
    • 84874171640 scopus 로고    scopus 로고
    • Interpenetrating polymer network of locust bean gum-poly (vinyl alcohol) for controlled release drug delivery
    • S.Kaity, J.Isaac, A.Ghosh. Interpenetrating polymer network of locust bean gum-poly (vinyl alcohol) for controlled release drug delivery. Carbohydr Polym. 2013;15:456–467.
    • (2013) Carbohydr Polym , vol.15 , pp. 456-467
    • Kaity, S.1    Isaac, J.2    Ghosh, A.3
  • 18
    • 84885395495 scopus 로고    scopus 로고
    • KGM and PMAA based pH-sensitive interpenetrating polymer network hydrogel for controlled drug release
    • Q.Xu, W.Huang, L.Jiang, et al. KGM and PMAA based pH-sensitive interpenetrating polymer network hydrogel for controlled drug release. Carbohydr Polym. 2013;97:565–570.
    • (2013) Carbohydr Polym , vol.97 , pp. 565-570
    • Xu, Q.1    Huang, W.2    Jiang, L.3
  • 19
    • 84866688350 scopus 로고    scopus 로고
    • Al3+ ion cross-linked interpenetrating polymeric network microbeads from tailored natural polysaccharides
    • S.S.Bhattacharya, A.K.Ghosh, S.Banerjee, et al. Al3+ ion cross-linked interpenetrating polymeric network microbeads from tailored natural polysaccharides. Int J Biol Macromol. 2012;51:1173–1184.
    • (2012) Int J Biol Macromol , vol.51 , pp. 1173-1184
    • Bhattacharya, S.S.1    Ghosh, A.K.2    Banerjee, S.3
  • 20
    • 42449137105 scopus 로고    scopus 로고
    • Studies on in vitro release of CPM from semi-interpenetrating polymer network (IPN) composed of chitosan and glutamic acid
    • K.Kumari, P.P.Kundu. Studies on in vitro release of CPM from semi-interpenetrating polymer network (IPN) composed of chitosan and glutamic acid. Bull Mater Sci. 2008;3:159–167.
    • (2008) Bull Mater Sci , vol.3 , pp. 159-167
    • Kumari, K.1    Kundu, P.P.2
  • 21
    • 77953331427 scopus 로고    scopus 로고
    • Chitosan-sodium alginate biodegradable interpenetrating polymer network (IPN) beads for delivery ofofloxacin hydrochloride
    • P.V.Kulkarni, J.Keshavayya. Chitosan-sodium alginate biodegradable interpenetrating polymer network (IPN) beads for delivery ofofloxacin hydrochloride. Int J Pharm Pharmaceut Sci. 2010;2:77–82.
    • (2010) Int J Pharm Pharmaceut Sci , vol.2 , pp. 77-82
    • Kulkarni, P.V.1    Keshavayya, J.2
  • 22
    • 77953155293 scopus 로고    scopus 로고
    • Interpenetrating network hydrogel beads of carboxymethylcellulose and egg albumin for controlled release of lipid lowering drug
    • R.Boppana, R.V.Kulkarni, S.S.Mutalik, et al. Interpenetrating network hydrogel beads of carboxymethylcellulose and egg albumin for controlled release of lipid lowering drug. J Microencap. 2010;27:337–344.
    • (2010) J Microencap , vol.27 , pp. 337-344
    • Boppana, R.1    Kulkarni, R.V.2    Mutalik, S.S.3
  • 23
    • 83555173320 scopus 로고    scopus 로고
    • Development of cloxacillin loaded multiple-unit alginate-based floating system by emulsion-gelation method
    • J.Malakar, A.K.Nayak, D.Pal. Development of cloxacillin loaded multiple-unit alginate-based floating system by emulsion-gelation method. Int J Biol Macromol. 2012;50:138–147.
    • (2012) Int J Biol Macromol , vol.50 , pp. 138-147
    • Malakar, J.1    Nayak, A.K.2    Pal, D.3
  • 24
    • 0032720381 scopus 로고    scopus 로고
    • Electrolyte-induced compositional heterogeneity: A novel approach for rate-controlled oral drug delivery
    • V.Pillay, R.Fassihi. Electrolyte-induced compositional heterogeneity: a novel approach for rate-controlled oral drug delivery. J Pharm Sci. 1999;88:1140–1148.
    • (1999) J Pharm Sci , vol.88 , pp. 1140-1148
    • Pillay, V.1    Fassihi, R.2
  • 25
    • 49149101874 scopus 로고    scopus 로고
    • In vitro release of bovine serum albumin from alginate/HPMC hydrogel beads
    • A.Nochos, D.Douroumis, N.Bouropoulos. In vitro release of bovine serum albumin from alginate/HPMC hydrogel beads. Carbohydr Polym. 2008;74:451–457.
    • (2008) Carbohydr Polym , vol.74 , pp. 451-457
    • Nochos, A.1    Douroumis, D.2    Bouropoulos, N.3
  • 26
    • 79960559977 scopus 로고    scopus 로고
    • Lectin-functionalized carboxymethylated kappa-carrageenan microparticles for oral insulin delivery
    • K.H.Leong, L.Y.Chung, M.I.Noordin, et al. Lectin-functionalized carboxymethylated kappa-carrageenan microparticles for oral insulin delivery. Carbohydr Polym. 2011;86:555–565.
    • (2011) Carbohydr Polym , vol.86 , pp. 555-565
    • Leong, K.H.1    Chung, L.Y.2    Noordin, M.I.3
  • 27
    • 33750073190 scopus 로고    scopus 로고
    • Novel chitosan-based pH-sensitive interpenetrating network microgels for the controlled release of cefadroxil
    • K.S.V.Krishna Rao, B.Vijaya Kumar Naidu, M.C.S.Subha, et al. Novel chitosan-based pH-sensitive interpenetrating network microgels for the controlled release of cefadroxil. Carbohydr Polym. 2006;66:333–344.
    • (2006) Carbohydr Polym , vol.66 , pp. 333-344
    • Krishna Rao, K.S.V.1    Vijaya Kumar Naidu, B.2    Subha, M.C.S.3
  • 28
    • 77956768140 scopus 로고    scopus 로고
    • Interpenetrating network hydrogel membranes of sodium alginate and poly(vinyl alcohol) for controlled release of prazosin hydrochloride through skin
    • R.V.Kulkarni, V.Sreedhar, S.Mutalik, et al. Interpenetrating network hydrogel membranes of sodium alginate and poly(vinyl alcohol) for controlled release of prazosin hydrochloride through skin. Int J Biol Macromol. 2010;47:520–527.
    • (2010) Int J Biol Macromol , vol.47 , pp. 520-527
    • Kulkarni, R.V.1    Sreedhar, V.2    Mutalik, S.3
  • 29
    • 84879880281 scopus 로고    scopus 로고
    • Development of ciprofloxacin hydrochloride loaded poly(ethylene glycol)/chitosan scaffold as wound dressing
    • M.Sinha, R.M.Banik, C.Haldar, et al. Development of ciprofloxacin hydrochloride loaded poly(ethylene glycol)/chitosan scaffold as wound dressing. J Por Mater. 2013;20:799–807.
    • (2013) J Por Mater , vol.20 , pp. 799-807
    • Sinha, M.1    Banik, R.M.2    Haldar, C.3
  • 32
    • 0346256860 scopus 로고    scopus 로고
    • Advances in biomaterials, drug delivery, and bionanotechnology
    • R.Langer, N.A.Peppas. Advances in biomaterials, drug delivery, and bionanotechnology. AIChE J. 2003;49:2990–3006.
    • (2003) AIChE J , vol.49 , pp. 2990-3006
    • Langer, R.1    Peppas, N.A.2
  • 33
    • 17544379636 scopus 로고    scopus 로고
    • Integrated medical feedback systems for drug delivery
    • A.Heller. Integrated medical feedback systems for drug delivery. AIChE J. 2005;51:1054–1066.
    • (2005) AIChE J , vol.51 , pp. 1054-1066
    • Heller, A.1
  • 34
    • 67650281482 scopus 로고    scopus 로고
    • Synthesis, characterization and biocompatibility of biodegradable elastomeric poly(ether-ester urethane)s based on poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) and poly(ethylene glycol) via melting polymerization
    • Z.Li, X.Yang, L.Wu, et al. Synthesis, characterization and biocompatibility of biodegradable elastomeric poly(ether-ester urethane)s based on poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) and poly(ethylene glycol) via melting polymerization. J Biomater Sci Polym Ed. 2009;20:1179–1202.
    • (2009) J Biomater Sci Polym Ed , vol.20 , pp. 1179-1202
    • Li, Z.1    Yang, X.2    Wu, L.3
  • 36
    • 77949898500 scopus 로고    scopus 로고
    • Drug release kinetics and transport mechanisms of non-degradable and degradable polymeric delivery systems
    • Y.Fu, W.J.Kao. Drug release kinetics and transport mechanisms of non-degradable and degradable polymeric delivery systems. Expert Opin Drug Deliv. 2010;7:429–444.
    • (2010) Expert Opin Drug Deliv , vol.7 , pp. 429-444
    • Fu, Y.1    Kao, W.J.2
  • 39
    • 84925634644 scopus 로고    scopus 로고
    • Biomedical applications of hydrogels: A review of patents and commercial products
    • E.Caló, V.V.Khutoryanskiy. Biomedical applications of hydrogels: A review of patents and commercial products. Eur Polym J. 2015;65:252–267.
    • (2015) Eur Polym J , vol.65 , pp. 252-267
    • Caló, E.1    Khutoryanskiy, V.V.2
  • 43
    • 84975196434 scopus 로고    scopus 로고
    • Available from
    • Ocular Therapeutix™. 2016. Available from: www.ocutx.com
    • (2016) Ocular Therapeutix™
  • 46
    • 84975200966 scopus 로고    scopus 로고
    • Available from
    • Cervidil website. Available from: www.cervidil.com.2015
    • Cervidil website
  • 52
    • 34547585979 scopus 로고    scopus 로고
    • Biodegradable polymers as biomaterials
    • L.S.Nair, C.T.Laurencin. Biodegradable polymers as biomaterials. Prog Polym Sci. 2007;32:762–798.
    • (2007) Prog Polym Sci , vol.32 , pp. 762-798
    • Nair, L.S.1    Laurencin, C.T.2
  • 53
    • 34548419647 scopus 로고    scopus 로고
    • Investigation of the degradation behavior of poly(ethylene glycol-co-D,L-lactide) copolymer
    • R.Dorati, I.Genta, C.Colonna, et al. Investigation of the degradation behavior of poly(ethylene glycol-co-D,L-lactide) copolymer. Polym Degrad Stabil. 2007;92:1660–1668.
    • (2007) Polym Degrad Stabil , vol.92 , pp. 1660-1668
    • Dorati, R.1    Genta, I.2    Colonna, C.3
  • 54
    • 84873244450 scopus 로고    scopus 로고
    • Advanced materials and processing for drug delivery: The past and the future
    • • Good review highlighting commercialized drug delivery systems
    • Y.Zhang, H.F.Chan, K.W.Leong. Advanced materials and processing for drug delivery: the past and the future. Adv Drug Deliv Rev. 2013;65:104–120.• Good review highlighting commercialized drug delivery systems.
    • (2013) Adv Drug Deliv Rev , vol.65 , pp. 104-120
    • Zhang, Y.1    Chan, H.F.2    Leong, K.W.3
  • 57
    • 0037410016 scopus 로고    scopus 로고
    • Crystalline transition of nylons 12, 20 and 10, 20
    • Y.Huang, W.Li, D.Yan. Crystalline transition of nylons 12, 20 and 10, 20. Eur Polym J. 2003;39:1133–1140.
    • (2003) Eur Polym J , vol.39 , pp. 1133-1140
    • Huang, Y.1    Li, W.2    Yan, D.3
  • 58
    • 13244251300 scopus 로고    scopus 로고
    • Preparation, characterization and crystalline transitions of odd-even polyamides 11, 12 and 11,10
    • X.Cui, D.Yan. Preparation, characterization and crystalline transitions of odd-even polyamides 11, 12 and 11,10. Eur Polym J. 2005;41:863–870.
    • (2005) Eur Polym J , vol.41 , pp. 863-870
    • Cui, X.1    Yan, D.2
  • 59
    • 2342659751 scopus 로고    scopus 로고
    • Synthesis and characterization of novel even–odd nylons based on undecanedioic acid
    • X.Cui, Z.Liu, D.Yan. Synthesis and characterization of novel even–odd nylons based on undecanedioic acid. Eur Polym J. 2004;40:1111–1118.
    • (2004) Eur Polym J , vol.40 , pp. 1111-1118
    • Cui, X.1    Liu, Z.2    Yan, D.3
  • 60
    • 0031140419 scopus 로고    scopus 로고
    • Chain-folded lamellar crystals of aliphatic polyamides. Investigation of nylons 4 8, 4 10, 4 12, 6 10, 6 12, 6 18, and 8 12
    • N.A.Jones, E.D.T.Atkins, M.J.Hill, et al. Chain-folded lamellar crystals of aliphatic polyamides. Investigation of nylons 4 8, 4 10, 4 12, 6 10, 6 12, 6 18, and 8 12. Polymer. 1997;38:2689–2699.
    • (1997) Polymer , vol.38 , pp. 2689-2699
    • Jones, N.A.1    Atkins, E.D.T.2    Hill, M.J.3
  • 61
    • 34250682153 scopus 로고    scopus 로고
    • Novel polyamide 6,10 variants synthesized by modified interfacial polymerization for application as a rate-modulated monolithic drug delivery system
    • O.A.Kolawole, V.Pillay, Y.E.Choonara. Novel polyamide 6,10 variants synthesized by modified interfacial polymerization for application as a rate-modulated monolithic drug delivery system. J Bioact Compat Polym. 2007;22:281–313.
    • (2007) J Bioact Compat Polym , vol.22 , pp. 281-313
    • Kolawole, O.A.1    Pillay, V.2    Choonara, Y.E.3
  • 62
    • 9544254878 scopus 로고    scopus 로고
    • Stimuli-reponsive polymers and their bioconjugates
    • E.S.Gil, S.A.Hudson. Stimuli-reponsive polymers and their bioconjugates. Prog Polym Sci. 2004;29:1173–1222.
    • (2004) Prog Polym Sci , vol.29 , pp. 1173-1222
    • Gil, E.S.1    Hudson, S.A.2
  • 63
    • 33751520245 scopus 로고    scopus 로고
    • Thermo- and pH-responsive polymers in drug delivery
    • D.Schmaljohann. Thermo- and pH-responsive polymers in drug delivery. Adv Drug Deliv Rev. 2006;58:1655–1670.
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 1655-1670
    • Schmaljohann, D.1
  • 64
    • 0004991063 scopus 로고
    • Poly (N-isopropylacrylamide): Experiment, theory and application
    • H.G.Schild. Poly (N-isopropylacrylamide): experiment, theory and application. Prog Polym Sci. 1992;17:163–249.
    • (1992) Prog Polym Sci , vol.17 , pp. 163-249
    • Schild, H.G.1
  • 65
    • 0029294457 scopus 로고
    • Swelling/deswelling of anionic copolymer gels
    • A.R.Khare, N.A.Peppas. Swelling/deswelling of anionic copolymer gels. Biomaterials. 1995;16:559–567.
    • (1995) Biomaterials , vol.16 , pp. 559-567
    • Khare, A.R.1    Peppas, N.A.2
  • 66
    • 0026923132 scopus 로고
    • Self-assembly in aqueous block copolymer solutions
    • M.Malmsten, B.Lindman. Self-assembly in aqueous block copolymer solutions. Macromolecules. 1992;25:5440–5445.
    • (1992) Macromolecules , vol.25 , pp. 5440-5445
    • Malmsten, M.1    Lindman, B.2
  • 67
    • 0031383195 scopus 로고    scopus 로고
    • Thermosensitive micelle-forming block copolymers of poly(ethylene glycol) and poly(N-isopropylacrylamide)
    • M.D.C.Topp, P.J.Dijkstra, H.Talsma, et al. Thermosensitive micelle-forming block copolymers of poly(ethylene glycol) and poly(N-isopropylacrylamide). Macromolecules. 1997;30:8518–8520.
    • (1997) Macromolecules , vol.30 , pp. 8518-8520
    • Topp, M.D.C.1    Dijkstra, P.J.2    Talsma, H.3
  • 68
    • 34247161019 scopus 로고    scopus 로고
    • Shape-memory polymers
    • M.Behl, A.Lendlein. Shape-memory polymers. Mater Today. 2007;10:20–28.
    • (2007) Mater Today , vol.10 , pp. 20-28
    • Behl, M.1    Lendlein, A.2
  • 69
    • 84975183597 scopus 로고    scopus 로고
    • Customized shape memory biopolymers
    • Pillay V., Choonara Y.E., Kumar P., (eds), Bentham Science Publishers
    • L.C.du Toit, T.Marimuthu, P.Kumar, et al. Customized shape memory biopolymers. In: V.Pillay, Y.E.Choonara, P.Kumar, editors. Unfolding the biopolymer landscape. Vol. 2. Sharjah: Bentham Science Publishers; 2016. p. 92–123.
    • (2016) Unfolding the biopolymer landscape , vol.2 , pp. 92-123
    • du Toit, L.C.1    Marimuthu, T.2    Kumar, P.3
  • 70
    • 84923797705 scopus 로고    scopus 로고
    • Shape-memory surfaces for cell mechanobiology
    • M.Ebara. Shape-memory surfaces for cell mechanobiology. Sci Technol Adv Mater. 2015;16:014804.
    • (2015) Sci Technol Adv Mater , vol.16 , pp. 014804
    • Ebara, M.1
  • 71
    • 0025875185 scopus 로고
    • Probing the mechanisms of drug release from hydrogels
    • P.I.Lee, C.J.Kim. Probing the mechanisms of drug release from hydrogels. J Control Rel. 1991;16:229–236.
    • (1991) J Control Rel , vol.16 , pp. 229-236
    • Lee, P.I.1    Kim, C.J.2
  • 81
    • 0037204998 scopus 로고    scopus 로고
    • Biodegradable, elastic shape-memory polymers for potential biomedical applications
    • A.Lendlein, R.Langer. Biodegradable, elastic shape-memory polymers for potential biomedical applications. Science. 2002;296:1673–1676.
    • (2002) Science , vol.296 , pp. 1673-1676
    • Lendlein, A.1    Langer, R.2
  • 82
    • 77951832882 scopus 로고    scopus 로고
    • Shape-memory polymers as a technology platform for biomedical applications
    • A.Lendlein, M.Behl, B.Hiebl, et al. Shape-memory polymers as a technology platform for biomedical applications. Expert Rev Med Device. 2010;7:357–379.
    • (2010) Expert Rev Med Device , vol.7 , pp. 357-379
    • Lendlein, A.1    Behl, M.2    Hiebl, B.3
  • 84
    • 17044379049 scopus 로고    scopus 로고
    • Shape-memory polymer networks from oligo(ϵ-caprolactone)dimethacrylates
    • A.Lendlein, A.M.Schmidt, M.Schroeter, et al. Shape-memory polymer networks from oligo(ϵ-caprolactone)dimethacrylates. J Polym Sci Part A: Polym Chem. 2005;43:1369–1381.
    • (2005) J Polym Sci Part A: Polym Chem , vol.43 , pp. 1369-1381
    • Lendlein, A.1    Schmidt, A.M.2    Schroeter, M.3
  • 85
    • 23444444512 scopus 로고
    • Biodegradable long-circulating polymeric nanospheres
    • R.Gref, Y.Minamitake, M.T.Peracchia, et al. Biodegradable long-circulating polymeric nanospheres. Science. 1994;263:1600–1603.
    • (1994) Science , vol.263 , pp. 1600-1603
    • Gref, R.1    Minamitake, Y.2    Peracchia, M.T.3
  • 87
    • 0037302269 scopus 로고    scopus 로고
    • Recent developments in polyurethanes and poly(acrylates) interpenetrating polymer networks
    • W.D.Athawale, S.L.Kolekar, S.S.Raut. Recent developments in polyurethanes and poly(acrylates) interpenetrating polymer networks. J Macromol Sci-Polym Rev. 2003;C43:1–26.
    • (2003) J Macromol Sci-Polym Rev , vol.C43 , pp. 1-26
    • Athawale, W.D.1    Kolekar, S.L.2    Raut, S.S.3
  • 88
    • 0025811822 scopus 로고
    • Thermoresponsive swelling and drug release switching of interpenetrating polymer networks composed of poly (acrylamide-co-butyl methacrylate) and poly (acrylic-acid)
    • H.Katono, A.Maruyama, K.Sanui, et al. Thermoresponsive swelling and drug release switching of interpenetrating polymer networks composed of poly (acrylamide-co-butyl methacrylate) and poly (acrylic-acid). J Control Release. 1991;16:215–227.
    • (1991) J Control Release , vol.16 , pp. 215-227
    • Katono, H.1    Maruyama, A.2    Sanui, K.3
  • 91
    • 84886292840 scopus 로고    scopus 로고
    • Stimuli-responsive nanocarriers for drug delivery
    • S.Mura, J.Nicolas, P.Couvreur. Stimuli-responsive nanocarriers for drug delivery. Nat Mater. 2013;12:991–1003.
    • (2013) Nat Mater , vol.12 , pp. 991-1003
    • Mura, S.1    Nicolas, J.2    Couvreur, P.3
  • 92
    • 84925272997 scopus 로고    scopus 로고
    • Interpenetrating polymer networks as innovative drug delivery systems
    • 583612, In-depth review of the use of IPNs in novel drug delivery systems
    • A.Lohani, G.Singh, S.S.Bhattacharya, et al. Interpenetrating polymer networks as innovative drug delivery systems. J Drug Deliv. 2014;2014:11. Article ID 583612. In-depth review of the use of IPNs in novel drug delivery systems.
    • (2014) J Drug Deliv , vol.2014 , pp. 11
    • Lohani, A.1    Singh, G.2    Bhattacharya, S.S.3
  • 93
    • 85009064672 scopus 로고    scopus 로고
    • Smart polymers for the controlled delivery of drugs – a concise overview
    • • Well-balanced article providing insight into the advantages and challenges of stimuli-responsive drug delivery systems
    • H.P.James, R.John, A.Alex, et al. Smart polymers for the controlled delivery of drugs – a concise overview. Acta Pharmaceutica Sinica B. 2014;4:120–127.• Well-balanced article providing insight into the advantages and challenges of stimuli-responsive drug delivery systems.
    • (2014) Acta Pharmaceutica Sinica B , vol.4 , pp. 120-127
    • James, H.P.1    John, R.2    Alex, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.