Cytocompatible injectable carboxymethyl chitosan/N-isopropylacrylamide hydrogels for localized drug delivery

Carbohydrate Polymers

Volumn 103, Issue 1, 2014, Pages 110-118

  Zhang, Lin ^a   Wang, Ling ^a   Guo, Baolin ^a   Ma, Peter X ^a,b  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Biodegradable injectable hydrogels; Carboxymethyl chitosan; Localized drug delivery; Photopolymerization; Poly (N isopropyl acrylamide)

Indexed keywords

ANTI-INFLAMMATORY DRUGS; CARBOXYMETHYL CHITOSAN; DICLOFENAC SODIUM; GLYCIDYL METHACRYLATE; INJECTABLE HYDROGELS; LOCALIZED DELIVERY; N-ISOPROPYLACRYLAMIDES; PH AND TEMPERATURE SENSITIVITIES;

ACRYLIC MONOMERS; AMIDES; CHITOSAN; CROSSLINKING; DRUG DELIVERY; GRAFTING (CHEMICAL); PH EFFECTS; PHOTOPOLYMERIZATION; SCANNING ELECTRON MICROSCOPY; STEM CELLS;

HYDROGELS;

ACRYLAMIDE DERIVATIVE; BIOMATERIAL; CARBOXYMETHYL CHITOSAN; CHITOSAN; CROSS LINKING REAGENT; DRUG CARRIER; DRUG DERIVATIVE; N ISOPROPYLACRYLAMIDE; N-ISOPROPYLACRYLAMIDE;

ANIMAL; ARTICLE; BIODEGRADABLE INJECTABLE HYDROGELS; CELL CULTURE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DOG; DRUG DELIVERY SYSTEM; HYDROGEL; LOCALIZED DRUG DELIVERY; PH; PHOTOPOLYMERIZATION; POLY (N-ISOPROPYL ACRYLAMIDE); SYNTHESIS; TEMPERATURE;

BIODEGRADABLE INJECTABLE HYDROGELS; CARBOXYMETHYL CHITOSAN; LOCALIZED DRUG DELIVERY; PHOTOPOLYMERIZATION; POLY (N-ISOPROPYL ACRYLAMIDE);

ACRYLAMIDES; ANIMALS; BIOCOMPATIBLE MATERIALS; CELL PROLIFERATION; CELLS, CULTURED; CHITOSAN; CROSS-LINKING REAGENTS; DOGS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HYDROGELS; HYDROGEN-ION CONCENTRATION; MOLECULAR STRUCTURE; TEMPERATURE;

EID: 84891601173     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2013.12.017     Document Type: Article

References (55)

1. Ajazuddin, A. Alexander, J. Khan, T.K. Giri, D.K. Tripathi, and S. Saraf Advancement in stimuli triggered in situ gelling delivery for local and systemic route Expert Opinion on Drug Delivery 9 12 2012 1573 1592
2. K.S. Anseth, A.T. Metters, S.J. Bryant, P.J. Martens, J.H. Elisseeff, and C.N. Bowman In situ forming degradable networks and their application in tissue engineering and drug delivery Journal of Controlled Release 78 1-3 2002 199 209 (Pubitemid 34081865)
3. C.S. Bahney, T.J. Lujan, C.W. Hsu, M. Bottlang, J.L. West, and B. Johnstone Visible light photoinitiation of mesenchymal stem cell-laden bioresponsive hydrogels European Cells & Materials 22 2010 43 55
4. R. Barbucci, R. Giardino, M. De Cagna, L. Golini, and D. Pasqui Inter-penetrating hydrogels (IPHs) as a new class of injectable polysaccharide hydrogels with thixotropic nature and interesting mechanical and biological properties Soft Matter 6 15 2010 3524 3532
5. A. Bernkop-Schnurch, and S. Dunnhaupt Chitosan-based drug delivery systems European Journal of Pharmaceutics and Biopharmaceutics 81 3 2012 463 469
6. A.S. Carreira, F. Goncalves, P.V. Mendonca, M.H. Gil, and J.F.J. Coelho Temperature and pH responsive polymers based on chitosan: Applications and new graft copolymerization strategies based on living radical polymerization Carbohydrate Polymers 80 3 2010 618 630
7. L.Y. Chen, Z.G. Tian, and Y.M. Du Synthesis and pH sensitivity of carboxymethyl chitosan-based polyampholyte hydrogels for protein carrier matrices Biomaterials 25 17 2004 3725 3732
8. S.B. Chen, H. Zhong, L.L. Zhang, Y.F. Wang, Z.P. Cheng, and Y.L. Zhu et al. Synthesis and characterization of thermoresponsive and biocompatible core-shell microgels based on N-isopropylacrylamide and carboxymethyl chitosan Carbohydrate Polymers 82 3 2010 747 752
9. T. Delair In situ forming polysaccharide-based 3D-hydrogels for cell delivery in regenerative medicine Carbohydrate Polymers 87 2 2012 1013 1019
10. M. Di Biase, P. de Leonardis, V. Castelletto, I.W. Hamley, B. Derby, and N. Tirelli Photopolymerization of Pluronic F127 diacrylate: A colloid-templated polymerization Soft Matter 7 10 2011 4928 4937
11. H.W. Du, P. Hamilton, M. Reilly, and N. Ravi Injectable in situ physically and chemically crosslinkable gellan hydrogel Macromolecular Bioscience 12 7 2012 952 961
12. J. Elisseeff, K. Anseth, D. Sims, W. McIntosh, M. Randolph, and R. Langer Transdermal photopolymerization for minimally invasive implantation Proceedings of the National Academy of Sciences of the United States of America 96 6 1999 3104 3107 (Pubitemid 29148851)
13. J. Elisseeff, K. Anseth, D. Sims, W. McIntosh, M. Randolph, and M. Yaremchuk et al. Transdermal photopolymerization of poly(ethylene oxide)-based injectable hydrogels for tissue-engineered cartilage Plastic and Reconstructive Surgery 104 4 1999 1014 1022 (Pubitemid 29413764)
14. E. Faizuloev, A. Marova, A. Nikonova, I. Volkova, M. Gorshkova, and V. Izumrudov Water-soluble N-[(2-hydroxy-3-trimethylammonium)propyl]chitosan chloride as a nucleic acids vector for cell transfection Carbohydrate Polymers 89 4 2012 1088 1094
15. X.Y. Gao, Y.S. Zhou, G.P. Ma, S.Q. Shi, D.Z. Yang, and F.M. Lu et al. A water-soluble photocrosslinkable chitosan derivative prepared by Michael-addition reaction as a precursor for injectable hydrogel Carbohydrate Polymers 79 3 2010 507 512
16. B.L. Guo, A. Finne-Wistrand, and A.C. Albertsson Degradable and electroactive hydrogels with tunable electrical conductivity and swelling behavior Chemistry of Materials 23 5 2011 1254 1262
17. B.L. Guo, A. Finne-Wistrand, and A.C. Albertsson Facile synthesis of degradable and electrically conductive polysaccharide hydrogels Biomacromolecules 12 7 2011 2601 2609
18. B.L. Guo, A. Finne-Wistrand, and A.C. Albertsson Versatile functionalization of polyester hydrogels with electroactive aniline oligomers Journal of Polymer Science Part A-Polymer Chemistry 49 9 2011 2097 2105
19. B.L. Guo, A. Finne-Wistrand, and A.C. Albertsson Electroactive hydrophilic polylactide surface by covalent modification with tetraaniline Macromolecules 45 2 2012 652 659
20. B.L. Guo, and Q.Y. Gao Preparation and properties of a pH/temperature-responsive carboxymethyl chitosan/poly(N-isopropylacrylamide) semi-IPN hydrogel for oral delivery of drugs Carbohydrate Research 342 16 2007 2416 2422
21. B.L. Guo, J.F. Yuan, and Q.Y. Gao Preparation and characterization of pH sensitive comb-shaped chitosan material for the controlled release of coenzyme A Journal of Materials Science-Materials in Medicine 18 5 2007 753 757
22. B.L. Guo, J.F. Yuan, and Q.Y. Gao Preparation and characterization of temperature and pH-sensitive chitosan material and its controlled release on coenzyme A Colloids and Surfaces B-Biointerfaces 58 2 2007 151 156
23. B.L. Guo, J.F. Yuan, and Q.Y. Gao pH and ionic sensitive chitosan/carboxymethyl chitosan IPN complex films for the controlled release of coenzyme A Colloid and Polymer Science 286 2 2008 175 181
24. B.L. Guo, J.F. Yuan, and Q.Y. Gao Preparation and release behavior of temperature- and pH-responsive chitosan material Polymer International 57 3 2008 463 468
25. B.L. Guo, J.F. Yuan, L. Yao, and Q.Y. Gao Preparation and release profiles of pH/temperature-responsive carboxymethyl chitosan/P(2-(dimethylamino) ethyl methacrylate) semi-IPN amphoteric hydrogel Colloid and Polymer Science 285 6 2007 665 671 (Pubitemid 46403983)
26. L.M. Hu, Y. Sun, and Y. Wu Advances in chitosan-based drug delivery vehicles Nanoscale 5 8 2013 3103 3111
27. S. Ichikawa, S. Iwamoto, and J. Watanabe Formation of biocompatible nanoparticles by self-assembly of enzymatic hydrolysates of chitosan and carboxymethyl cellulose Bioscience Biotechnology and Biochemistry 69 9 2005 1637 1642 (Pubitemid 41390148)
28. J.L. Ifkovits, and J.A. Burdick Review: Photopolymerizable and degradable biomaterials for tissue engineering applications Tissue Engineering 13 10 2007 2369 2385 (Pubitemid 47571700)
29. M. Iijima, and Y. Nagasaki Synthesis of poly[N-isopropylacrylamide-g- poly(ethylene glycol)] with a reactive group at the poly(ethylene glycol) end and its thermosensitive self-assembling character Journal of Polymer Science Part A-Polymer Chemistry 44 4 2006 1457 1469
30. K. Ito Polymeric design by macromonomer technique Progress in Polymer Science 23 4 1998 581 620 (Pubitemid 128676067)
31. R. Jayakumar, M. Prabaharan, S.V. Nair, S. Tokura, H. Tamura, and N. Selvamurugan Novel carboxymethyl derivatives of chitin and chitosan materials and their biomedical applications Progress in Materials Science 55 7 2010 675 709
32. D.Y. Kim, D.Y. Kwon, B.N. Lee, H.W. Seo, J.S. Kwon, and B. Lee et al. Injectable in situ-forming hydrogels for a suppression of drug burst from drug-loaded microcapsules Soft Matter 8 29 2012 7638 7648
33. D.Y. Ko, U.P. Shinde, B. Yeon, and B. Jeong Recent progress of in situ formed gels for biomedical applications Progress in Polymer Science 38 3-4 2013 672 701
34. Y.L. Li, J. Rodrigues, and H. Tomas Injectable and biodegradable hydrogels: Gelation, biodegradation and biomedical applications Chemical Society Reviews 41 6 2012 2193 2221
35. Z.Q. Li, J.F. Shen, H.W. Ma, X. Lu, M. Shi, and N. Li et al. Preparation and characterization of pH- and temperature-responsive hydrogels with surface-functionalized graphene oxide as the crosslinker Soft Matter 8 11 2012 3139 3145
36. R.Z. Lin, Y.C. Chen, R. Moreno-Luna, A. Khademhosseini, and J.M. Melero-Martin Transdermal regulation of vascular network bioengineering using a photopolymerizable methacrylated gelatin hydrogel Biomaterials 34 28 2013 6785 6796
37. J. Mao, S.Q. Bo, and X.L. Ji pH/temperature-responsive behavior of amphiphilic block copolymer micelles prepared using two different methods Langmuir 27 12 2011 7385 7391
38. T. Nakai, T. Hirakura, Y. Sakurai, T. Shimoboji, M. Ishigai, and K. Akiyoshi Injectable hydrogel for sustained protein release by salt-induced association of hyaluronic acid nanogel Macromolecular Bioscience 12 4 2012 475 483
39. R.A. Ortiz, A.Y.R. Martinez, A.E.G. Valdez, and M.L.B. Duarte Preparation of a crosslinked sucrose polymer by thiol-ene photopolymerization using dithiothreitol as comonomer Carbohydrate Polymers 82 3 2010 822 828
40. D.J. Overstreet, D. Dutta, S.E. Stabenfeldt, and B.L. Vernon Injectable hydrogels Journal of Polymer Science Part B-Polymer Physics 50 13 2012 881 903
41. M. Patenaude, and T. Hoare Injectable, degradable thermoresponsive poly(N-isopropylacrylamide) hydrogels ACS Macro Letters 1 3 2012 409 413
42. Y. Qiu, and K. Park Environment-sensitive hydrogels for drug delivery Advanced Drug Delivery Reviews 64 2012 49 60
43. C.V. Rahman, A. Saeed, L.J. White, T.W.A. Gould, G.T.S. Kirby, and M.J. Sawkins et al. Chemistry of polymer and ceramic-based injectable scaffolds and their applications in regenerative medicine Chemistry of Materials 24 5 2012 781 795
44. A. Schmalz, H. Schmalz, and A.H.E. Muller Smart hydrogels based on responsive star-block copolymers Soft Matter 8 36 2012 9436 9445
45. H.P. Tan, and K.G. Marra Injectable, biodegradable hydrogels for tissue engineering applications Materials 3 3 2010 1746 1767
46. Y. Tang, and J. Singh Biodegradable and biocompatible thermosensitive polymer based injectable implant for controlled release of protein International Journal of Pharmaceutics 365 1/2 2009 34 43
47. L. Upadhyaya, J. Singh, V. Agarwal, and R.P. Tewari Biomedical applications of carboxymethyl chitosans Carbohydrate Polymers 91 1 2013 452 466
48. J. Wang, J.S. Chen, J.Y. Zong, D. Zhao, F. Li, and R.X. Zhuo et al. Calcium carbonate/carboxymethyl chitosan hybrid microspheres and nanospheres for drug delivery Journal of Physical Chemistry C 114 44 2010 18940 18945
49. H. Wei, S.X. Cheng, X.Z. Zhang, and R.X. Zhuo Thermo-sensitive polymeric micelles based on poly(N-isopropylacrylamide) as drug carriers Progress in Polymer Science 34 9 2009 893 910
50. H.J. Yu, C. Deng, H.Y. Tian, T.C. Lu, X.S. Chen, and X.B. Jing Chemo-physical and biological evaluation of poly(l-lysine)-grafted chitosan copolymers used for highly efficient gene delivery Macromolecular Bioscience 11 3 2011 352 361
51. L. Yu, and J.D. Ding Injectable hydrogels as unique biomedical materials Chemical Society Reviews 37 8 2008 1473 1481
52. H.F. Zhang, H. Zhong, L.L. Zhang, S.B. Chen, Y.J. Zhao, and Y.L. Zhu Synthesis and characterization of thermosensitive graft copolymer of N-isopropylacrylamide with biodegradable carboxymethylchitosan Carbohydrate Polymers 77 4 2009 785 790
53. Y. Zhang, F. Zhan, and W.F. Shi Photopolymerization behavior and properties of highly branched poly(thioether-urethane) acrylates used for UV-curing coatings Progress in Organic Coatings 71 4 2011 399 405
54. H.Y. Zhou, Y.P. Zhang, W.F. Zhang, and X.G. Chen Biocompatibility and characteristics of injectable chitosan-based thermosensitive hydrogel for drug delivery Carbohydrate Polymers 83 4 2011 1643 1651
55. A.P. Zhu, M.B. Chan-Park, S. Dai, and L. Li The aggregation behavior of O-carboxymethylchitosan in dilute aqueous solution Colloids and Surfaces B-Biointerfaces 43 3-4 2005 143 149 (Pubitemid 40909834)