Birth by caesarean section and the risk of adult psychosis: A population-based cohort study

Schizophrenia Bulletin

Volumn 42, Issue 3, 2016, Pages 633-641

  O'Neill, Sinéad M ^a   Curran, Eileen A ^a   Dalman, Christina ^b   Kenny, Louise C ^a,c   Kearney, Patricia M ^d   Clarke, Gerard ^d,e   Cryan, John F ^d,e   Dinan, Timothy G ^d,e   Khashan, Ali S ^a,d  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b KAROLINSKA INSTITUTE   (Sweden)

^c Irish Centre for Fetal and Neonatal Translational Research   (Ireland)

^d UNIVERSITY COLLEGE CORK   (Ireland)

^e UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Caesarean; confounding; mode of delivery; psychosis; sibling control

Indexed keywords

ADULT DISEASE; ARTICLE; ASSISTED VAGINAL DELIVERY; BIPOLAR DISORDER; CESAREAN SECTION; COHORT ANALYSIS; DEPRESSION; ELECTIVE SURGERY; ICD-10; LIVE BIRTH; OBSTETRIC DELIVERY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGENY; PSYCHOSIS; REGISTER; SCHIZOPHRENIA; SWEDEN; UNASSISTED VAGINAL DELIVERY; ADOLESCENT; ADULT; ADVERSE EFFECTS; FEMALE; HUMAN; MALE; PSYCHOTIC DISORDERS; STATISTICS AND NUMERICAL DATA; YOUNG ADULT;

ADOLESCENT; ADULT; CESAREAN SECTION; COHORT STUDIES; DELIVERY, OBSTETRIC; ELECTIVE SURGICAL PROCEDURES; FEMALE; HUMANS; MALE; PSYCHOTIC DISORDERS; REGISTRIES; SWEDEN; YOUNG ADULT;

EID: 84966389454     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbv152     Document Type: Article

References (42)

1. Keshavan MS, Giedd J, Lau JY, et al. Changes in the adolescent brain and the pathophysiology of psychotic disorders. Lancet Psychiatry. 2014; 1: 549-558
2. Kelleher I, Connor D, Clarke MC, et al. Prevalence of psychotic symptoms in childhood and adolescence: a systematic review and meta-Analysis of population-based studies. Psychol Med. 2012; 42: 1857-1863
3. Linscott RJ, van Os J. An updated and conservative systematic review and meta-Analysis of epidemiological evidence on psychotic experiences in children and adults: on the pathway from proneness to persistence to dimensional expression across mental disorders. Psychol Med. 2013; 43: 1133-1149
4. Bruenig D, White MJ, Young RM, et al. Subclinical psychotic experiences in healthy young adults: associations with stress and genetic predisposition. Genet Test Mol Biomarkers. 2014; 18: 683-689
5. Eisenberger NI, Cole SW. Social neuroscience and health: neurophysiological mechanisms linking social ties with physical health. Nat Neurosci. 2012; 15: 669-674
6. Cryan JF, Dinan TG. Mind-Altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nat Rev Neurosci. 2012; 13: 701-712
7. Kavanagh D, Tansey K, O Donovan M, et al. Schizophrenia genetics: emerging themes for a complex disorder. Mol Psychiatry. 2014; 20: 72-76
8. Chudal R, Sourander A, Polo-Kantola P, et al. Perinatal factors and the risk of bipolar disorder in Finland. J Affect Disord. 2014; 155: 75-80
9. Borre YE, O Keeffe GW, Clarke G, et al. Microbiota and neurodevelopmental windows: implications for brain disorders. Trends Mol Med. 2014; 20: 509-518
10. Stilling RM, Dinan TG, Cryan JF. Microbial genes, brain & behaviour-epigenetic regulation of the gut-brain axis. Genes Brain Behav. 2014; 13: 69-86
11. Mackay DF, Smith GC, Dobbie R, et al. Obstetric factors and different causes of special educational need: retrospective cohort study of 407, 503 schoolchildren. BJOG. 2013; 120: 297-307
12. Cho CE, Norman M. Cesarean section and development of the immune system in the offspring. Am J Obstet Gynecol. 2013; 208: 249-254
13. Curran EA, Dalman C, Kearney PM, et al. Association between obstetric mode of delivery and autism spectrum disorder: a population-based sibling design study. JAMA Psychiatry. 2015; 72: 935-942
14. Rosso IM, Cannon TD, Huttunen T, et al. Obstetric risk factors for early-onset schizophrenia in a Finnish birth cohort. Am J Psychiatry. 2000; 157: 801-807
15. Clarke MC, Tanskanen A, Huttunen M, et al. Increased risk of schizophrenia from additive interaction between infant motor developmental delay and obstetric complications: evidence from a population-based longitudinal study. Am J Psychiatry. 2011; 168: 1295-1302
16. McNeil TF, Cantor-Graae E, Weinberger DR. Relationship of obstetric complications and differences in size of brain structures in monozygotic twin pairs discordant for schizophrenia. Am J Psychiatry. 2000; 157: 203-212
17. Rubio-Abadal E, Ochoa S, Barajas A, et al. Birth weight and obstetric complications determine age at onset in first episode of psychosis. J Psychiatr Res. 2015; 65: 108-114
18. Abel KM, Heuvelman HP, Jörgensen L, et al. Severe bereavement stress during the prenatal and childhood periods and risk of psychosis in later life: population based cohort study. BMJ. 2014; 348: f7679
19. Cannon M, Jones PB, Murray RM. Obstetric complications and schizophrenia: historical and meta-Analytic review. Am J Psychiatry. 2002; 159: 1080-1092
20. Bain M, Juszczak E, McInneny K, Kendell RE. Obstetric complications and affective psychoses. Two case-control studies based on structured obstetric records. Br J Psychiatry. 2000; 176: 523-526
21. Chudal R, Sourander A, Polo-Kantola P, et al. Perinatal factors and the risk of bipolar disorder in Finland. J Affect Disord. 2014; 155: 75-80
22. Ludvigsson JF, Otterblad-Olausson P, Pettersson BU, Ekbom A. The Swedish personal identity number: possibilities and pitfalls in healthcare and medical research. Eur J Epidemiol. 2009; 24: 659-667
23. Axelsson O. The Swedish medical birth register. Acta Obstet Gynecol Scand. 2003; 82: 491-492
24. Ludvigsson JF, Andersson E, Ekbom A, et al. External review and validation of the Swedish national inpatient register. BMC Public Health. 2011; 11: 450
25. Ekbom A. The Swedish multi-generation register. Methods Biobank. 2011: 215-220
26. Nosarti C, Reichenberg A, Murray RM, et al. Preterm birth and psychiatric disorders in young adult life. Arch Gen Psychiary. 2012; 69: 610-617
27. Textor J, Hardt J, Knüppel S. DAGitty: a graphical tool for analyzing causal diagrams. Epidemiology. 2011; 22: 745
28. Fazel S, Bakiyeva L, Cnattingius S, et al. Perinatal risk factors in offenders with severe personality disorder: a population-based investigation. J Pers Disord. 2012; 26: 737-750
29. Groenwold RH, White IR, Donders ART, et al. Missing covariate data in clinical research: when and when not to use the missing-indicator method for analysis. Cand Med Assoc. 2012; 184: 1265-1269
30. Allison P. Estimating Cox regression models with PROC PHREG. Survival analysis using the SAS system. 2000: 111-184
31. Bain M, Juszczak E, McInneny K, et al. Obstetric complications and affective psychoses. Two case-control studies based on structured obstetric records. Br J Psychiatry. 2000; 176: 523-526
32. Dalman C, Allebeck P, Cullberg J, et al. Obstetric complications and the risk of schizophrenia: a longitudinal study of a national birth cohort. Arch Gen Psychiatry. 1999; 56: 234-240
33. Verdoux H, Geddes JR, Takei N, et al. Obstetric complications and age at onset in schizophrenia: an international collaborative meta-Analysis of individual patient data. Am J Psychiatry. 1997; 154: 1220-1227
34. Sellgren C, Landén M, Lichtenstein P, et al. Validity of bipolar disorder hospital discharge diagnoses: file review and multiple register linkage in Sweden. Acta Psychiatr Scand. 2011; 124: 447-453
35. Ekholm B, Ekholm A, Adolfsson R, et al. Evaluation of diagnostic procedures in Swedish patients with schizophrenia and related psychoses. Nord J Psychiatry. 2005; 59: 457-464
36. Frisell T, Öberg S, Kuja-Halkola R, et al. Sibling comparison designs: bias from non-shared confounders and measurement error. Epidemiology. 2012; 23: 713-720
37. Donovan SJ, Susser E. Commentary: advent of sibling designs. Int J Epidemiol. 2011; 40: 345-349
38. Macfarlane A, Blondel B, Mohangoo A, et al. Wide differences in mode of delivery within Europe: risk-stratified analyses of aggregated routine data from the Euro-Peristat study. BJOG
39. Fagerberg MC, Maršál K, Källén K. Predicting the chance of vaginal delivery after one cesarean section: validation and elaboration of a published prediction model. Eur J Obstet Gynecol Reprod Biol. 2015; 188: 88-94
40. Keyes KM, Smith GD, Susser E. On sibling designs. Epidemiology. 2013; 24: 473-474
41. Lavender T, Hofmeyr GJ, Neilson JP, et al. Caesarean section for non-medical reasons at term. Cochrane Database Syst Rev. 2012
42. Frisell T, Öberg S, Kuja-Halkola R, et al. Sibling comparison designs: bias from non-shared confounders and measurement error. Epidemiology. 2012; 23: 713-720