-
1
-
-
0030987778
-
The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4
-
Imai T., Baba M., Nishimura M., Kakizaki M., Takagi S., Yoshie O. The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4. J. Biol. Chem 1997, 272:15036-15042.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 15036-15042
-
-
Imai, T.1
Baba, M.2
Nishimura, M.3
Kakizaki, M.4
Takagi, S.5
Yoshie, O.6
-
2
-
-
0031893264
-
Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4
-
Imai T., Chantry D., Raport C.J., Wood C.L., Nishimura M., Godiska R., et al. Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4. J. Biol. Chem 1998, 273:1764-1768.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 1764-1768
-
-
Imai, T.1
Chantry, D.2
Raport, C.J.3
Wood, C.L.4
Nishimura, M.5
Godiska, R.6
-
3
-
-
0032908743
-
Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine
-
Imai T., Nagira M., Takagi S., Kakizaki M., Nishimura M., Wang J., et al. Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine. Int. Immunol 1999, 11:81-88.
-
(1999)
Int. Immunol
, vol.11
, pp. 81-88
-
-
Imai, T.1
Nagira, M.2
Takagi, S.3
Kakizaki, M.4
Nishimura, M.5
Wang, J.6
-
4
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel T.J., Coukos G., Zou L., Alvarez X., Cheng P., Mottram P., et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med 2004, 10:942-949.
-
(2004)
Nat. Med
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
-
5
-
-
40449111457
-
Human Th17 cells share major trafficking receptors with both polarized effector T cells and FOXP3+ regulatory T cells
-
Lim H.W., Lee J., Hillsamer P., Kim C.H. Human Th17 cells share major trafficking receptors with both polarized effector T cells and FOXP3+ regulatory T cells. J. Immunol 2008, 180:122-129.
-
(2008)
J. Immunol
, vol.180
, pp. 122-129
-
-
Lim, H.W.1
Lee, J.2
Hillsamer, P.3
Kim, C.H.4
-
6
-
-
72849131815
-
Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling
-
Eyerich S., Eyerich K., Pennino D., Carbone T., Nasorri F., Pallotta S., et al. Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. J. Clin. Invest 2009, 119:3573-3585.
-
(2009)
J. Clin. Invest
, vol.119
, pp. 3573-3585
-
-
Eyerich, S.1
Eyerich, K.2
Pennino, D.3
Carbone, T.4
Nasorri, F.5
Pallotta, S.6
-
7
-
-
43949105866
-
Regulatory T cells and immune tolerance
-
Sakaguchi S., Yamaguchi T., Nomura T., Ono M. Regulatory T cells and immune tolerance. Cell 2008, 133:775-787.
-
(2008)
Cell
, vol.133
, pp. 775-787
-
-
Sakaguchi, S.1
Yamaguchi, T.2
Nomura, T.3
Ono, M.4
-
8
-
-
0034716925
-
Regulatory T cells: key controllers of immunologic self-tolerance
-
Sakaguchi S. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 2000, 101:455-458.
-
(2000)
Cell
, vol.101
, pp. 455-458
-
-
Sakaguchi, S.1
-
9
-
-
77950992076
-
Tumor-infiltrating lymphocytes, particularly the balance between CD8(+) T cells and CCR4(+) regulatory T cells, affect the survival of patients with oral squamous cell carcinoma
-
Watanabe Y., Katou F., Ohtani H., Nakayama T., Yoshie O., Hashimoto K. Tumor-infiltrating lymphocytes, particularly the balance between CD8(+) T cells and CCR4(+) regulatory T cells, affect the survival of patients with oral squamous cell carcinoma. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod 2010, 109:744-752.
-
(2010)
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod
, vol.109
, pp. 744-752
-
-
Watanabe, Y.1
Katou, F.2
Ohtani, H.3
Nakayama, T.4
Yoshie, O.5
Hashimoto, K.6
-
10
-
-
3242736641
-
Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice
-
Jones E., Dahm-Vicker M., Simon A.K., Green A., Powrie F., Cerundolo V., et al. Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice. Cancer Immun 2002, 2:1.
-
(2002)
Cancer Immun
, vol.2
, pp. 1
-
-
Jones, E.1
Dahm-Vicker, M.2
Simon, A.K.3
Green, A.4
Powrie, F.5
Cerundolo, V.6
-
11
-
-
80855156710
-
A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens
-
Pere H., Montier Y., Bayry J., Quintin-Colonna F., Merillon N., Dransart E., et al. A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens. Blood 2011, 118:4853-4862.
-
(2011)
Blood
, vol.118
, pp. 4853-4862
-
-
Pere, H.1
Montier, Y.2
Bayry, J.3
Quintin-Colonna, F.4
Merillon, N.5
Dransart, E.6
-
12
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish C.L., Chen Y., Blumenschein W.M., Mattson J., Basham B., Sedgwick J.D., et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med 2005, 201:233-240.
-
(2005)
J. Exp. Med
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
-
13
-
-
77957689108
-
Role of Th17 cells in human autoimmune arthritis
-
Leipe J., Grunke M., Dechant C., Reindl C., Kerzendorf U., Schulze-Koops H., et al. Role of Th17 cells in human autoimmune arthritis. Arthritis Rheum 2012, 62:2876-2885.
-
(2012)
Arthritis Rheum
, vol.62
, pp. 2876-2885
-
-
Leipe, J.1
Grunke, M.2
Dechant, C.3
Reindl, C.4
Kerzendorf, U.5
Schulze-Koops, H.6
-
14
-
-
79958025270
-
Th17 cells induce colitis and promote Th1 cell responses through IL-17 induction of innate IL-12 and IL-23 production
-
Feng T., Qin H., Wang L., Benveniste E.N., Elson C.O., Cong Y. Th17 cells induce colitis and promote Th1 cell responses through IL-17 induction of innate IL-12 and IL-23 production. J. Immunol 2011, 186:6313-6318.
-
(2011)
J. Immunol
, vol.186
, pp. 6313-6318
-
-
Feng, T.1
Qin, H.2
Wang, L.3
Benveniste, E.N.4
Elson, C.O.5
Cong, Y.6
-
15
-
-
70449530422
-
T helper 17 cells promote cytotoxic T cell activation in tumor immunity
-
Martin-Orozco N., Muranski P., Chung Y., Yang X.O., Yamazaki T., Lu S., et al. T helper 17 cells promote cytotoxic T cell activation in tumor immunity. Immunity 2009, 31:787-798.
-
(2009)
Immunity
, vol.31
, pp. 787-798
-
-
Martin-Orozco, N.1
Muranski, P.2
Chung, Y.3
Yang, X.O.4
Yamazaki, T.5
Lu, S.6
-
16
-
-
80054121352
-
Th17 and Th17-stimulated CD8(+) T cells play a distinct role in Th17-induced preventive and therapeutic antitumor immunity
-
Ankathatti Munegowda M., Deng Y., Mulligan S.J., Xiang J. Th17 and Th17-stimulated CD8(+) T cells play a distinct role in Th17-induced preventive and therapeutic antitumor immunity. Cancer Immunol. Immunother 2011, 60:1473-1484.
-
(2011)
Cancer Immunol. Immunother
, vol.60
, pp. 1473-1484
-
-
Ankathatti Munegowda, M.1
Deng, Y.2
Mulligan, S.J.3
Xiang, J.4
-
17
-
-
33846202995
-
Core exploration in optimization of chemokine receptor CCR4 antagonists
-
Purandare A.V., Wan H., Somerville J.E., Burke C., Vaccaro W., Yang X., et al. Core exploration in optimization of chemokine receptor CCR4 antagonists. Bioorg. Med. Chem. Lett 2007, 17:679-682.
-
(2007)
Bioorg. Med. Chem. Lett
, vol.17
, pp. 679-682
-
-
Purandare, A.V.1
Wan, H.2
Somerville, J.E.3
Burke, C.4
Vaccaro, W.5
Yang, X.6
-
18
-
-
0032885058
-
Molecular cloning of mXCR1, the murine SCM-1/lymphotactin receptor
-
Yoshida T., Izawa D., Nakayama T., Nakahara K., Kakizaki M., Imai T., et al. Molecular cloning of mXCR1, the murine SCM-1/lymphotactin receptor. FEBS Lett 1999, 458:37-40.
-
(1999)
FEBS Lett
, vol.458
, pp. 37-40
-
-
Yoshida, T.1
Izawa, D.2
Nakayama, T.3
Nakahara, K.4
Kakizaki, M.5
Imai, T.6
-
19
-
-
0035914708
-
CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin
-
Reiss Y., Proudfoot A.E., Power C.A., Campbell J.J., Butcher E.C. CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin. J. Exp. Med 2001, 194:1541-1547.
-
(2001)
J. Exp. Med
, vol.194
, pp. 1541-1547
-
-
Reiss, Y.1
Proudfoot, A.E.2
Power, C.A.3
Campbell, J.J.4
Butcher, E.C.5
-
20
-
-
79959415857
-
Chemokine receptor requirements for epidermal T-cell trafficking
-
Tubo N.J., McLachlan J.B., Campbell J.J. Chemokine receptor requirements for epidermal T-cell trafficking. Am. J. Pathol 2011, 178:2496-2503.
-
(2011)
Am. J. Pathol
, vol.178
, pp. 2496-2503
-
-
Tubo, N.J.1
McLachlan, J.B.2
Campbell, J.J.3
-
21
-
-
84916883542
-
Plasmacytoid dendritic cells support melanoma progression by promoting Th2 and regulatory immunity through OX40L and ICOSL
-
Aspord C., Leccia M.T., Charles J., Plumas J. Plasmacytoid dendritic cells support melanoma progression by promoting Th2 and regulatory immunity through OX40L and ICOSL. Cancer Immunol. Res 2013, 1:402-415.
-
(2013)
Cancer Immunol. Res
, vol.1
, pp. 402-415
-
-
Aspord, C.1
Leccia, M.T.2
Charles, J.3
Plumas, J.4
-
22
-
-
84899804081
-
A requirement of dendritic cell-derived interleukin-27 for the tumor infiltration of regulatory T cells
-
Xia S., Wei J., Wang J., Sun H., Zheng W., Li Y., et al. A requirement of dendritic cell-derived interleukin-27 for the tumor infiltration of regulatory T cells. J. Leukoc. Biol 2014, 95:733-742.
-
(2014)
J. Leukoc. Biol
, vol.95
, pp. 733-742
-
-
Xia, S.1
Wei, J.2
Wang, J.3
Sun, H.4
Zheng, W.5
Li, Y.6
-
23
-
-
0037416171
-
Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen
-
Alferink J., Lieberam I., Reindl W., Behrens A., Weiss S., Huser N., et al. Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen. J. Exp. Med 2003, 197:585-599.
-
(2003)
J. Exp. Med
, vol.197
, pp. 585-599
-
-
Alferink, J.1
Lieberam, I.2
Reindl, W.3
Behrens, A.4
Weiss, S.5
Huser, N.6
-
24
-
-
0035072806
-
Macrophage-derived chemokine (MDC/CCL22) and CCR4 are involved in the formation of T lymphocyte-dendritic cell clusters in human inflamed skin and secondary lymphoid tissue
-
Katou F., Ohtani H., Nakayama T., Ono K., Matsushima K., Saaristo A., et al. Macrophage-derived chemokine (MDC/CCL22) and CCR4 are involved in the formation of T lymphocyte-dendritic cell clusters in human inflamed skin and secondary lymphoid tissue. Am. J. Pathol 2001, 158:1263-1270.
-
(2001)
Am. J. Pathol
, vol.158
, pp. 1263-1270
-
-
Katou, F.1
Ohtani, H.2
Nakayama, T.3
Ono, K.4
Matsushima, K.5
Saaristo, A.6
-
25
-
-
59849090484
-
CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation
-
Medoff B.D., Seung E., Hong S., Thomas S.Y., Sandall B.P., Duffield J.S., et al. CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation. J. Immunol 2009, 182:623-635.
-
(2009)
J. Immunol
, vol.182
, pp. 623-635
-
-
Medoff, B.D.1
Seung, E.2
Hong, S.3
Thomas, S.Y.4
Sandall, B.P.5
Duffield, J.S.6
-
26
-
-
84863058550
-
Selective down-regulation of Th2 cell-mediated airway inflammation in mice by pharmacological intervention of CCR4
-
Kaminuma O., Ohtomo T., Mori A., Nagakubo D., Hieshima K., Ohmachi Y., et al. Selective down-regulation of Th2 cell-mediated airway inflammation in mice by pharmacological intervention of CCR4. Clin. Exp. Allergy 2012, 42:315-325.
-
(2012)
Clin. Exp. Allergy
, vol.42
, pp. 315-325
-
-
Kaminuma, O.1
Ohtomo, T.2
Mori, A.3
Nagakubo, D.4
Hieshima, K.5
Ohmachi, Y.6
-
27
-
-
55749116154
-
Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansion
-
Chizzolini C., Chicheportiche R., Alvarez M., de Rham C., Roux-Lombard P., Ferrari-Lacraz S., et al. Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansion. Blood 2008, 112:3696-3703.
-
(2008)
Blood
, vol.112
, pp. 3696-3703
-
-
Chizzolini, C.1
Chicheportiche, R.2
Alvarez, M.3
de Rham, C.4
Roux-Lombard, P.5
Ferrari-Lacraz, S.6
-
28
-
-
9144219649
-
Cutting edge: TGF-beta signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory CD4+CD25+ T cells
-
Huber S., Schramm C., Lehr H.A., Mann A., Schmitt S., Becker C., et al. Cutting edge: TGF-beta signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory CD4+CD25+ T cells. J. Immunol 2004, 173:6526-6531.
-
(2004)
J. Immunol
, vol.173
, pp. 6526-6531
-
-
Huber, S.1
Schramm, C.2
Lehr, H.A.3
Mann, A.4
Schmitt, S.5
Becker, C.6
-
29
-
-
33846923124
-
IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells
-
Zheng S.G., Wang J., Wang P., Gray J.D., Horwitz D.A. IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells. J. Immunol 2007, 178:2018-2027.
-
(2007)
J. Immunol
, vol.178
, pp. 2018-2027
-
-
Zheng, S.G.1
Wang, J.2
Wang, P.3
Gray, J.D.4
Horwitz, D.A.5
-
30
-
-
65549145080
-
Human memory CCR4+CD8+ T cell subset has the ability to produce multiple cytokines
-
Kondo T., Takiguchi M. Human memory CCR4+CD8+ T cell subset has the ability to produce multiple cytokines. Int. Immunol 2009, 21:523-532.
-
(2009)
Int. Immunol
, vol.21
, pp. 523-532
-
-
Kondo, T.1
Takiguchi, M.2
-
31
-
-
7444247430
-
CXC chemokine receptor 3 expression by activated CD8+ T cells is associated with survival in melanoma patients with stage III disease
-
Mullins I.M., Slingluff C.L., Lee J.K., Garbee C.F., Shu J., Anderson S.G., et al. CXC chemokine receptor 3 expression by activated CD8+ T cells is associated with survival in melanoma patients with stage III disease. Cancer Res 2004, 64:7697-7701.
-
(2004)
Cancer Res
, vol.64
, pp. 7697-7701
-
-
Mullins, I.M.1
Slingluff, C.L.2
Lee, J.K.3
Garbee, C.F.4
Shu, J.5
Anderson, S.G.6
-
33
-
-
44349111367
-
Aberrant expression of Fra-2 promotes CCR4 expression and cell proliferation in adult T-cell leukemia
-
Nakayama T., Hieshima K., Arao T., Jin Z., Nagakubo D., Shirakawa A.K., et al. Aberrant expression of Fra-2 promotes CCR4 expression and cell proliferation in adult T-cell leukemia. Oncogene 2008, 27:3221-3232.
-
(2008)
Oncogene
, vol.27
, pp. 3221-3232
-
-
Nakayama, T.1
Hieshima, K.2
Arao, T.3
Jin, Z.4
Nagakubo, D.5
Shirakawa, A.K.6
-
34
-
-
84879697872
-
SOX4 is a direct target gene of FRA-2 and induces expression of HDAC8 in adult T-cell leukemia/lymphoma
-
Higuchi T., Nakayama T., Arao T., Nishio K., Yoshie O. SOX4 is a direct target gene of FRA-2 and induces expression of HDAC8 in adult T-cell leukemia/lymphoma. Blood 2013, 121:3640-3649.
-
(2013)
Blood
, vol.121
, pp. 3640-3649
-
-
Higuchi, T.1
Nakayama, T.2
Arao, T.3
Nishio, K.4
Yoshie, O.5
-
35
-
-
77951916883
-
Phase I study of KW-0761, a defucosylated humanized anti-CCR4 antibody, in relapsed patients with adult T-cell leukemia-lymphoma and peripheral T-cell lymphoma
-
Yamamoto K., Utsunomiya A., Tobinai K., Tsukasaki K., Uike N., Uozumi K., et al. Phase I study of KW-0761, a defucosylated humanized anti-CCR4 antibody, in relapsed patients with adult T-cell leukemia-lymphoma and peripheral T-cell lymphoma. J. Clin. Oncol 2010, 28:1591-1598.
-
(2010)
J. Clin. Oncol
, vol.28
, pp. 1591-1598
-
-
Yamamoto, K.1
Utsunomiya, A.2
Tobinai, K.3
Tsukasaki, K.4
Uike, N.5
Uozumi, K.6
-
36
-
-
84863393084
-
Defucosylated anti-CCR4 monoclonal antibody (KW-0761) for relapsed adult T-cell leukemia-lymphoma: a multicenter phase II study
-
Ishida T., Joh T., Uike N., Yamamoto K., Utsunomiya A., Yoshida S., et al. Defucosylated anti-CCR4 monoclonal antibody (KW-0761) for relapsed adult T-cell leukemia-lymphoma: a multicenter phase II study. J. Clin. Oncol 2012, 30:837-842.
-
(2012)
J. Clin. Oncol
, vol.30
, pp. 837-842
-
-
Ishida, T.1
Joh, T.2
Uike, N.3
Yamamoto, K.4
Utsunomiya, A.5
Yoshida, S.6
-
37
-
-
84887081136
-
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans
-
Sugiyama D., Nishikawa H., Maeda Y., Nishioka M., Tanemura A., Katayama I., et al. Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:17945-17950.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 17945-17950
-
-
Sugiyama, D.1
Nishikawa, H.2
Maeda, Y.3
Nishioka, M.4
Tanemura, A.5
Katayama, I.6
-
38
-
-
84945978548
-
Phase Ia Study of FoxP3+ CD4 Treg Depletion by Infusion of a Humanized Anti-CCR4 Antibody, KW-0761, in Cancer Patients
-
Kurose K., Ohue Y., Wada H., Iida S., Ishida T., Kojima T., et al. Phase Ia Study of FoxP3+ CD4 Treg Depletion by Infusion of a Humanized Anti-CCR4 Antibody, KW-0761, in Cancer Patients. Clin. Cancer Res 2015, 21:4327-4336.
-
(2015)
Clin. Cancer Res
, vol.21
, pp. 4327-4336
-
-
Kurose, K.1
Ohue, Y.2
Wada, H.3
Iida, S.4
Ishida, T.5
Kojima, T.6
|