Selective down-regulation of Th2 cell-mediated airway inflammation in mice by pharmacological intervention of CCR4

Clinical and Experimental Allergy

Volumn 42, Issue 2, 2012, Pages 315-325

  Kaminuma, O ^a,b   Ohtomo, T ^b   Mori, A ^b   Nagakubo, D ^c   Hieshima, K ^c   Ohmachi, Y ^d   Noda, Y ^d   Katayama, K ^a   Suzuki, K ^a   Motoi, Y ^a   Kitamura, N ^a   Saeki, M ^a   Nishimura, T ^a   Yoshie, O ^c   Hiroi, T ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b SAGAMIHARA NATIONAL HOSPITAL   (Japan)

^c KINKI UNIVERSITY   (Japan)

^d NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

Airway inflammation; Bronchial hyperresponsiveness; Chemokine; Eosinophil; Lung; T cell

Indexed keywords

CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR6; CYTOKINE ANTIBODY; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 5; OVALBUMIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; CELL HYPERPLASIA; CELL INFILTRATION; CELLULAR IMMUNITY; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; EOSINOPHIL; GOBLET CELL; IMMUNE RESPONSE; IN VITRO STUDY; INFLAMMATORY CELL; LUNG; LUNG INFILTRATE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTIC INFILTRATION; MOUSE; MUCUS SECRETION; NEUTROPHIL; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; RESPIRATORY TRACT INFLAMMATION; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH17 CELL; TH2 CELL;

ADOPTIVE TRANSFER; ANIMALS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; GOBLET CELLS; INFLAMMATION; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; RECEPTORS, CCR4; RECEPTORS, CCR6; RESPIRATORY HYPERSENSITIVITY; TH1 CELLS; TH17 CELLS; TH2 CELLS;

EID: 84863058550     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2011.03847.x     Document Type: Article

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