-
2
-
-
0029813545
-
+ TH1-like responses
-
+ TH1-like responses. J. Clin. Invest. 98: 1010-1020.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1010-1020
-
-
Berg, D.J.1
Davidson, N.2
Kühn, R.3
Müller, W.4
Menon, S.5
Holland, G.6
Thompson-Snipes, L.7
Leach, M.W.8
Rennick, D.9
-
3
-
-
0030209985
-
+ Lamina Propria (LP) Lymphokine Secretion Profiles in Inflammatory Bowel Disease: Crohn's Disease LP Cells Manifest Increased Secretion of IFN-γ, whereas Ulcerative Colitis LP Cells Manifest Increased Secretion of IL-5
-
Fuss, I. J., M. Neurath, M. Boirivant, J. S. Klein, C. de la Motte, S. A. Strong, C. Fiocchi, and W. Strober. 1996. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease: Crohn's disease LP cells manifest increased secretion of IFN-γ, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J. Immunol. 157: 1261-1270. (Pubitemid 126449643)
-
(1996)
Journal of Immunology
, vol.157
, Issue.3
, pp. 1261-1270
-
-
Fuss, I.J.1
Neurath, M.2
Boirivant, M.3
Klein, J.S.4
De La, M.C.5
Strong, S.A.6
Fiocchi, C.7
Strober, W.8
-
4
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen, D., J. Cheung, H. Scheerens, F. Poulet, T. McClanahan, B. McKenzie, M. A. Kleinschek, A. Owyang, J. Mattson, W. Blumenschein, et al. 2006. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J. Clin. Invest. 116: 1310-1316.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
Poulet, F.4
McClanahan, T.5
McKenzie, B.6
Kleinschek, M.A.7
Owyang, A.8
Mattson, J.9
Blumenschein, W.10
-
5
-
-
34250026960
-
Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice
-
Elson, C. O., Y. Cong, C. T.Weaver, T. R. Schoeb, T. K. McClanahan, R. B. Fick, and R. A. Kastelein. 2007. Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice. Gastroenterology 132: 2359-2370.
-
(2007)
Gastroenterology
, vol.132
, pp. 2359-2370
-
-
Elson, C.O.1
Cong, Y.2
Weaver, C.T.3
Schoeb, T.R.4
McClanahan, T.K.5
Fick, R.B.6
Kastelein, R.A.7
-
7
-
-
33646560950
-
H17 lineage
-
H17 lineage. Nature 441: 231-234.
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
Helms, W.S.4
Bullard, D.C.5
Elson, C.O.6
Hatton, R.D.7
Wahl, S.M.8
Schoeb, T.R.9
Weaver, C.T.10
-
8
-
-
0030995575
-
Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells
-
DOI 10.1016/S0016-5085(97)70128-8
-
Monteleone, G., L. Biancone, R. Marasco, G. Morrone, O. Marasco, F. Luzza, and F. Pallone. 1997. Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Gastroenterology 112: 1169-1178. (Pubitemid 27157528)
-
(1997)
Gastroenterology
, vol.112
, Issue.4
, pp. 1169-1178
-
-
Monteleone, G.1
Biancone, L.2
Marasco, R.3
Morrone, G.4
Marasco, O.5
Luzza, F.6
Pallone, F.7
-
9
-
-
13944281011
-
Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: Elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis
-
Schmidt, C., T. Giese, B. Ludwig, I. Mueller-Molaian, T. Marth, S. Zeuzem, S. C. Meuer, and A. Stallmach. 2005. Expression of interleukin-12- related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis. Inflamm. Bowel Dis. 11: 16-23.
-
(2005)
Inflamm. Bowel Dis.
, vol.11
, pp. 16-23
-
-
Schmidt, C.1
Giese, T.2
Ludwig, B.3
Mueller-Molaian, I.4
Marth, T.5
Zeuzem, S.6
Meuer, S.C.7
Stallmach, A.8
-
10
-
-
56549104968
-
IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease
-
Kobayashi, T., S. Okamoto, T. Hisamatsu, N. Kamada, H. Chinen, R. Saito, M. T. Kitazume, A. Nakazawa, A. Sugita, K. Koganei, et al. 2008. IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease. Gut 57: 1682-1689.
-
(2008)
Gut
, vol.57
, pp. 1682-1689
-
-
Kobayashi, T.1
Okamoto, S.2
Hisamatsu, T.3
Kamada, N.4
Chinen, H.5
Saito, R.6
Kitazume, M.T.7
Nakazawa, A.8
Sugita, A.9
Koganei, K.10
-
11
-
-
70350093623
-
Th1/Th17 immune response is induced by mesenteric lymph node dendritic cells in Crohn's disease
-
Sakuraba, A., T. Sato, N. Kamada, M. Kitazume, A. Sugita, and T. Hibi. 2009. Th1/Th17 immune response is induced by mesenteric lymph node dendritic cells in Crohn's disease. Gastroenterology 137: 1736-1745.
-
(2009)
Gastroenterology
, vol.137
, pp. 1736-1745
-
-
Sakuraba, A.1
Sato, T.2
Kamada, N.3
Kitazume, M.4
Sugita, A.5
Hibi, T.6
-
12
-
-
29744450121
-
Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody
-
Fuss, I. J., C. Becker, Z. Yang, C. Groden, R. L. Hornung, F. Heller, M. F. Neurath, W. Strober, and P. J. Mannon. 2006. Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody. Inflamm. Bowel Dis. 12: 9-15.
-
(2006)
Inflamm. Bowel Dis.
, vol.12
, pp. 9-15
-
-
Fuss, I.J.1
Becker, C.2
Yang, Z.3
Groden, C.4
Hornung, R.L.5
Heller, F.6
Neurath, M.F.7
Strober, W.8
Mannon, P.J.9
-
13
-
-
0033558364
-
+ T cells that respond to bacterial antigens
-
+ T cells that respond to bacterial antigens. J. Immunol. 162: 1884-1888.
-
(1999)
J. Immunol.
, vol.162
, pp. 1884-1888
-
-
Wirtz, S.1
Finotto, S.2
Kanzler, S.3
Lohse, A.W.4
Blessing, M.5
Lehr, H.A.6
Galle, P.R.7
Neurath, M.F.8
-
14
-
-
0037029649
-
The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease
-
Neurath, M. F., B. Weigmann, S. Finotto, J. Glickman, E. Nieuwenhuis, H. Iijima, A. Mizoguchi, E. Mizoguchi, J. Mudter, P. R. Galle, et al. 2002. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease. J. Exp. Med. 195: 1129-1143.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1129-1143
-
-
Neurath, M.F.1
Weigmann, B.2
Finotto, S.3
Glickman, J.4
Nieuwenhuis, E.5
Iijima, H.6
Mizoguchi, A.7
Mizoguchi, E.8
Mudter, J.9
Galle, P.R.10
-
15
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
DOI 10.1126/science.1135245
-
Duerr, R. H., K. D. Taylor, S. R. Brant, J. D. Rioux, M. S. Silverberg, M. J. Daly, A. H. Steinhart, C. Abraham, M. Regueiro, A. Griffiths, et al. 2006. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 314: 1461-1463. (Pubitemid 44871953)
-
(2006)
Science
, vol.314
, Issue.5804
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
Rioux, J.D.4
Silverberg, M.S.5
Daly, M.J.6
Steinhart, A.H.7
Abraham, C.8
Regueiro, M.9
Griffiths, A.10
Dassopoulos, T.11
Bitton, A.12
Yang, H.13
Targan, S.14
Datta, L.W.15
Kistner, E.O.16
Schumm, L.P.17
Lee, A.T.18
Gregersen, P.K.19
Barmada, M.M.20
Rotter, J.I.21
Nicolae, D.L.22
Cho, J.H.23
more..
-
16
-
-
58949097704
-
Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship
-
Anderson, C. A., D. C. Massey, J. C. Barrett, N. J. Prescott, M. Tremelling, S. A. Fisher, R. Gwilliam, J. Jacob, E. R. Nimmo, H. Drummond, et al. 2009. Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship. Gastroenterology 136: 523-529.
-
(2009)
Gastroenterology
, vol.136
, pp. 523-529
-
-
Anderson, C.A.1
Massey, D.C.2
Barrett, J.C.3
Prescott, N.J.4
Tremelling, M.5
Fisher, S.A.6
Gwilliam, R.7
Jacob, J.8
Nimmo, E.R.9
Drummond, H.10
-
17
-
-
44349124113
-
The genetics and immunopathogenesis of inflammatory bowel disease
-
Cho, J. H. 2008. The genetics and immunopathogenesis of inflammatory bowel disease. Nat. Rev. Immunol. 8: 458-466.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 458-466
-
-
Cho, J.H.1
-
18
-
-
59149087627
-
Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study
-
Silverberg, M. S., J. H. Cho, J. D. Rioux, D. P. McGovern, J. Wu, V. Annese, J. P. Achkar, P. Goyette, R. Scott, W. Xu, et al. 2009. Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study. Nat. Genet. 41: 216-220.
-
(2009)
Nat. Genet.
, vol.41
, pp. 216-220
-
-
Silverberg, M.S.1
Cho, J.H.2
Rioux, J.D.3
McGovern, D.P.4
Wu, J.5
Annese, V.6
Achkar, J.P.7
Goyette, P.8
Scott, R.9
Xu, W.10
-
19
-
-
8344284998
-
Anti-interleukin-12 antibody for active Crohn's disease
-
DOI 10.1056/NEJMoa033402
-
Mannon, P. J., I. J. Fuss, L. Mayer, C. O. Elson, W. J. Sandborn, D. Present, B. Dolin, N. Goodman, C. Groden, R. L. Hornung, et al; Anti-IL-12 Crohn's Disease Study Group. 2004. Anti-interleukin-12 antibody for active Crohn's disease. N. Engl. J. Med. 351: 2069-2079. (Pubitemid 39482500)
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.20
, pp. 2069-2079
-
-
Mannon, P.J.1
Fuss, I.J.2
Mayer, L.3
Elson, C.O.4
Sandborn, W.J.5
Present, D.6
Dolin, B.7
Goodman, N.8
Groden, C.9
Hornung, R.L.10
Quezado, M.11
Neurath, M.F.12
Salfeld, J.13
Veldman, G.M.14
Schwertschlag, U.15
Strober, W.16
-
20
-
-
53049091561
-
A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease
-
Ustekinumab Crohn's Disease Study Group
-
Sandborn, W. J., B. G. Feagan, R. N. Fedorak, E. Scherl, M. R. Fleisher, S. Katz, J. Johanns, M. Blank, P. Rutgeerts; Ustekinumab Crohn's Disease Study Group. 2008. A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease. Gastroenterology 135: 1130-1141.
-
(2008)
Gastroenterology
, vol.135
, pp. 1130-1141
-
-
Sandborn, W.J.1
Feagan, B.G.2
Fedorak, R.N.3
Scherl, E.4
Fleisher, M.R.5
Katz, S.6
Johanns, J.7
Blank, M.8
Rutgeerts, P.9
-
21
-
-
45749107055
-
Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-γ axis
-
Kamada, N., T. Hisamatsu, S. Okamoto, H. Chinen, T. Kobayashi, T. Sato, A. Sakuraba, M. T. Kitazume, A. Sugita, K. Koganei, et al. 2008. Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-γ axis. J. Clin. Invest. 118: 2269-2280.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 2269-2280
-
-
Kamada, N.1
Hisamatsu, T.2
Okamoto, S.3
Chinen, H.4
Kobayashi, T.5
Sato, T.6
Sakuraba, A.7
Kitazume, M.T.8
Sugita, A.9
Koganei, K.10
-
22
-
-
34547734621
-
Phenotypic and functional features of human Th17 cells
-
Annunziato, F., L. Cosmi, V. Santarlasci, L. Maggi, F. Liotta, B. Mazzinghi, E. Parente, L. Filì, S. Ferri, F. Frosali, et al. 2007. Phenotypic and functional features of human Th17 cells. J. Exp. Med. 204: 1849-1861.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1849-1861
-
-
Annunziato, F.1
Cosmi, L.2
Santarlasci, V.3
Maggi, L.4
Liotta, F.5
Mazzinghi, B.6
Parente, E.7
Filì, L.8
Ferri, S.9
Frosali, F.10
-
23
-
-
34249079176
-
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
-
Acosta-Rodriguez, E. V., L. Rivino, J. Geginat, D. Jarrossay, M. Gattorno, A. Lanzavecchia, F. Sallusto, and G. Napolitani. 2007. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat. Immunol. 8: 639-646.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 639-646
-
-
Acosta-Rodriguez, E.V.1
Rivino, L.2
Geginat, J.3
Jarrossay, D.4
Gattorno, M.5
Lanzavecchia, A.6
Sallusto, F.7
Napolitani, G.8
-
24
-
-
58149251898
-
Late developmental plasticity in the T helper 17 lineage
-
Lee, Y. K., H. Turner, C. L. Maynard, J. R. Oliver, D. Chen, C. O. Elson, and C. T. Weaver. 2009. Late developmental plasticity in the T helper 17 lineage. Immunity 30: 92-107.
-
(2009)
Immunity
, vol.30
, pp. 92-107
-
-
Lee, Y.K.1
Turner, H.2
Maynard, C.L.3
Oliver, J.R.4
Chen, D.5
Elson, C.O.6
Weaver, C.T.7
-
25
-
-
58149216715
-
Th memory for interleukin-17 expression is stable in vivo
-
Lexberg, M. H., A. Taubner, A. Förster, I. Albrecht, A. Richter, T. Kamradt, A. Radbruch, and H. D. Chang. 2008. Th memory for interleukin-17 expression is stable in vivo. Eur. J. Immunol. 38: 2654-2664.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 2654-2664
-
-
Lexberg, M.H.1
Taubner, A.2
Förster, A.3
Albrecht, I.4
Richter, A.5
Kamradt, T.6
Radbruch, A.7
Chang, H.D.8
-
26
-
-
60549086638
-
Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells
-
Martin-Orozco, N., Y. Chung, S. H. Chang, Y. H. Wang, and C. Dong. 2009. Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells. Eur. J. Immunol. 39: 216-224.
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 216-224
-
-
Martin-Orozco, N.1
Chung, Y.2
Chang, S.H.3
Wang, Y.H.4
Dong, C.5
-
27
-
-
64849103287
-
Cutting edge: In vitro generated Th17 cells maintain their cytokine expression program in normal but not lymphopenic hosts
-
Nurieva, R., X. O. Yang, Y. Chung, and C. Dong. 2009. Cutting edge: in vitro generated Th17 cells maintain their cytokine expression program in normal but not lymphopenic hosts. J. Immunol. 182: 2565-2568.
-
(2009)
J. Immunol.
, vol.182
, pp. 2565-2568
-
-
Nurieva, R.1
Yang, X.O.2
Chung, Y.3
Dong, C.4
-
28
-
-
73349099737
-
A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota
-
Cong, Y., T. Feng, K. Fujihashi, T. R. Schoeb, and C. O. Elson. 2009. A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota. Proc. Natl. Acad. Sci. USA 106: 19256-19261.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 19256-19261
-
-
Cong, Y.1
Feng, T.2
Fujihashi, K.3
Schoeb, T.R.4
Elson, C.O.5
-
30
-
-
68949149159
-
TGF-β promotes Th17 cell development through inhibition of SOCS3
-
Qin, H., L. Wang, T. Feng, C. O. Elson, S. A. Niyongere, S. J. Lee, S. L. Reynolds, C. T. Weaver, K. Roarty, R. Serra, et al. 2009. TGF-β promotes Th17 cell development through inhibition of SOCS3. J. Immunol. 183: 97-105.
-
(2009)
J. Immunol.
, vol.183
, pp. 97-105
-
-
Qin, H.1
Wang, L.2
Feng, T.3
Elson, C.O.4
Niyongere, S.A.5
Lee, S.J.6
Reynolds, S.L.7
Weaver, C.T.8
Roarty, K.9
Serra, R.10
-
31
-
-
0036883901
-
Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora
-
Cong, Y., C. T. Weaver, A. Lazenby, and C. O. Elson. 2002. Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora. J. Immunol. 169: 6112-6119.
-
(2002)
J. Immunol.
, vol.169
, pp. 6112-6119
-
-
Cong, Y.1
Weaver, C.T.2
Lazenby, A.3
Elson, C.O.4
-
32
-
-
2342646956
-
Bacterial flagellin is a dominant antigen in Crohn disease
-
Lodes, M. J., Y. Cong, C. O. Elson, R. Mohamath, C. J. Landers, S. R. Targan, M. Fort, and R. M. Hershberg. 2004. Bacterial flagellin is a dominant antigen in Crohn disease. J. Clin. Invest. 113: 1296-1306.
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 1296-1306
-
-
Lodes, M.J.1
Cong, Y.2
Elson, C.O.3
Mohamath, R.4
Landers, C.J.5
Targan, S.R.6
Fort, M.7
Hershberg, R.M.8
-
34
-
-
77953486362
-
Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitis
-
Feng, T., L. Wang, T. R. Schoeb, C. O. Elson, and Y. Cong. 2010. Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitis. J. Exp. Med. 207: 1321-1332.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1321-1332
-
-
Feng, T.1
Wang, L.2
Schoeb, T.R.3
Elson, C.O.4
Cong, Y.5
-
35
-
-
35349019357
-
Isolation of flagellated bacteria implicated in Crohn's disease
-
Duck, L. W., M. R. Walter, J. Novak, D. Kelly, M. Tomasi, Y. Cong, and C. O. Elson. 2007. Isolation of flagellated bacteria implicated in Crohn's disease. Inflamm. Bowel Dis. 13: 1191-1201.
-
(2007)
Inflamm. Bowel Dis.
, vol.13
, pp. 1191-1201
-
-
Duck, L.W.1
Walter, M.R.2
Novak, J.3
Kelly, D.4
Tomasi, M.5
Cong, Y.6
Elson, C.O.7
-
36
-
-
0842324613
-
Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice
-
Ogawa, A., A. Andoh, Y. Araki, T. Bamba, and Y. Fujiyama. 2004. Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice. Clin. Immunol. 110: 55-62.
-
(2004)
Clin. Immunol.
, vol.110
, pp. 55-62
-
-
Ogawa, A.1
Andoh, A.2
Araki, Y.3
Bamba, T.4
Fujiyama, Y.5
-
37
-
-
65749091607
-
A protective function for interleukin 17A in T cell-mediated intestinal inflammation
-
O'Connor, W., Jr., M. Kamanaka, C. J. Booth, T. Town, S. Nakae, Y. Iwakura, J. K. Kolls, and R. A. Flavell. 2009. A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nat. Immunol. 10: 603-609.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 603-609
-
-
O'Connor Jr., W.1
Kamanaka, M.2
Booth, C.J.3
Town, T.4
Nakae, S.5
Iwakura, Y.6
Kolls, J.K.7
Flavell, R.A.8
-
38
-
-
54449102022
-
Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice
-
Ito, R., M. Kita, M. Shin-Ya, T. Kishida, A. Urano, R. Takada, J. Sakagami, J. Imanishi, Y. Iwakura, T. Okanoue, et al. 2008. Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice. Biochem. Biophys. Res. Commun. 377: 12-16.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.377
, pp. 12-16
-
-
Ito, R.1
Kita, M.2
Shin-Ya, M.3
Kishida, T.4
Urano, A.5
Takada, R.6
Sakagami, J.7
Imanishi, J.8
Iwakura, Y.9
Okanoue, T.10
-
39
-
-
78651500757
-
Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORγt and LTi cells
-
Lochner, M., C. Ohnmacht, L. Presley, P. Bruhns, M. Si-Tahar, S. Sawa, and G. Eberl. 2010. Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORγt and LTi cells. J. Exp. Med. 208: 125-134.
-
(2010)
J. Exp. Med.
, vol.208
, pp. 125-134
-
-
Lochner, M.1
Ohnmacht, C.2
Presley, L.3
Bruhns, P.4
Si-Tahar, M.5
Sawa, S.6
Eberl, G.7
-
40
-
-
78049385155
-
+ innate lymphoid cells
-
+ innate lymphoid cells. Science 330: 665-669.
-
(2010)
Science
, vol.330
, pp. 665-669
-
-
Sawa, S.1
Cherrier, M.2
Lochner, M.3
Satoh-Takayama, N.4
Fehling, H.J.5
Langa, F.6
Di Santo, J.P.7
Eberl, G.8
-
41
-
-
79952986650
-
+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota
-
+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota. Nat. Immunol. 12: 320-326.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 320-326
-
-
Sawa, S.1
Lochner, M.2
Satoh-Takayama, N.3
Dulauroy, S.4
Berard, M.5
Kleinschek, M.6
Cua, D.7
Di Santo, J.P.8
Eberl, G.9
-
42
-
-
70449501815
-
Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis
-
Lin, Y., S. Ritchea, A. Logar, S. Slight, M. Messmer, J. Rangel-Moreno, L. Guglani, J. F. Alcorn, H. Strawbridge, S. M. Park, et al. 2009. Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis. Immunity 31: 799-810.
-
(2009)
Immunity
, vol.31
, pp. 799-810
-
-
Lin, Y.1
Ritchea, S.2
Logar, A.3
Slight, S.4
Messmer, M.5
Rangel-Moreno, J.6
Guglani, L.7
Alcorn, J.F.8
Strawbridge, H.9
Park, S.M.10
-
43
-
-
41549160626
-
Interleukin-23 Restrains Regulatory T Cell Activity to Drive T Cell-Dependent Colitis
-
DOI 10.1016/j.immuni.2008.02.019, PII S1074761308001167
-
Izcue, A., S. Hue, S. Buonocore, C. V. Arancibia-Cárcamo, P. P. Ahern, Y. Iwakura, K. J. Maloy, and F. Powrie. 2008. Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis. Immunity 28: 559-570. (Pubitemid 351467043)
-
(2008)
Immunity
, vol.28
, Issue.4
, pp. 559-570
-
-
Izcue, A.1
Hue, S.2
Buonocore, S.3
Arancibia-Carcamo, C.V.4
Ahern, P.P.5
Iwakura, Y.6
Maloy, K.J.7
Powrie, F.8
-
44
-
-
59849114998
-
RORγ-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F
-
Leppkes, M., C. Becker, I. I. Ivanov, S. Hirth, S. Wirtz, C. Neufert, S. Pouly, A. J. Murphy, D. M. Valenzuela, G. D. Yancopoulos, et al. 2009. RORγ-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F. Gastroenterology 136: 257-267.
-
(2009)
Gastroenterology
, vol.136
, pp. 257-267
-
-
Leppkes, M.1
Becker, C.2
Ivanov, I.I.3
Hirth, S.4
Wirtz, S.5
Neufert, C.6
Pouly, S.7
Murphy, A.J.8
Valenzuela, D.M.9
Yancopoulos, G.D.10
-
45
-
-
33750530394
-
IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis
-
Kullberg, M. C., D. Jankovic, C. G. Feng, S. Hue, P. L. Gorelick, B. S. McKenzie, D. J. Cua, F. Powrie, A. W. Cheever, K. J. Maloy, and A. Sher. 2006. IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. J. Exp. Med. 203: 2485-2494.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2485-2494
-
-
Kullberg, M.C.1
Jankovic, D.2
Feng, C.G.3
Hue, S.4
Gorelick, P.L.5
McKenzie, B.S.6
Cua, D.J.7
Powrie, F.8
Cheever, A.W.9
Maloy, K.J.10
Sher, A.11
-
46
-
-
33747089041
-
Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology
-
Uhlig, H. H., B. S. McKenzie, S. Hue, C. Thompson, B. Joyce-Shaikh, R. Stepankova, N. Robinson, S. Buonocore, H. Tlaskalova-Hogenova, D. J. Cua, and F. Powrie. 2006. Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology. Immunity 25: 309-318.
-
(2006)
Immunity
, vol.25
, pp. 309-318
-
-
Uhlig, H.H.1
McKenzie, B.S.2
Hue, S.3
Thompson, C.4
Joyce-Shaikh, B.5
Stepankova, R.6
Robinson, N.7
Buonocore, S.8
Tlaskalova-Hogenova, H.9
Cua, D.J.10
Powrie, F.11
-
47
-
-
67449147595
-
Interleukin-23/Th17 pathways and inflammatory bowel disease
-
Abraham, C., and J. Cho. 2009. Interleukin-23/Th17 pathways and inflammatory bowel disease. Inflamm. Bowel Dis. 15: 1090-1100.
-
(2009)
Inflamm. Bowel Dis.
, vol.15
, pp. 1090-1100
-
-
Abraham, C.1
Cho, J.2
-
48
-
-
4344688669
-
IL-17 markedly up-regulates β-defensin-2 expression in human airway epithelium via JAK and NF-κB signaling pathways
-
Kao, C. Y., Y. Chen, P. Thai, S. Wachi, F. Huang, C. Kim, R. W. Harper, and R. Wu. 2004. IL-17 markedly up-regulates β-defensin-2 expression in human airway epithelium via JAK and NF-κB signaling pathways. J. Immunol. 173: 3482-3491. (Pubitemid 39142059)
-
(2004)
Journal of Immunology
, vol.173
, Issue.5
, pp. 3482-3491
-
-
Kao, C.-Y.1
Chen, Y.2
Thai, P.3
Wachi, S.4
Huang, F.5
Kim, C.6
Harper, R.W.7
Wu, R.8
-
49
-
-
33749318470
-
Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
-
Liang, S. C., X. Y. Tan, D. P. Luxenberg, R. Karim, K. Dunussi-Joannopoulos, M. Collins, and L. A. Fouser. 2006. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J. Exp. Med. 203: 2271-2279.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2271-2279
-
-
Liang, S.C.1
Tan, X.Y.2
Luxenberg, D.P.3
Karim, R.4
Dunussi-Joannopoulos, K.5
Collins, M.6
Fouser, L.A.7
-
50
-
-
41549135632
-
The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation
-
DOI 10.1016/j.immuni.2008.03.004, PII S1074761308001192
-
Ouyang, W., J. K. Kolls, and Y. Zheng. 2008. The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity 28: 454-467. (Pubitemid 351471762)
-
(2008)
Immunity
, vol.28
, Issue.4
, pp. 454-467
-
-
Ouyang, W.1
Kolls, J.K.2
Zheng, Y.3
-
51
-
-
69349093225
-
Interleukin-17 and type 17 helper T cells
-
Miossec, P., T. Korn, and V. K. Kuchroo. 2009. Interleukin-17 and type 17 helper T cells. N. Engl. J. Med. 361: 888-898.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 888-898
-
-
Miossec, P.1
Korn, T.2
Kuchroo, V.K.3
|