Poly(glycidyl methacrylate-co-2-hydroxyethyl methacrylate) Brushes as Peptide/Protein Microarray Substrate for Improving Protein Binding and Functionality

ACS Applied Materials and Interfaces

Volumn 8, Issue 16, 2016, Pages 10174-10182

  Lei, Zhen ^a,b   Gao, Jiaxue ^a,b   Liu, Xia ^a   Liu, Dianjun ^a   Wang, Zhenxin ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

binding of human IgG with rabbit antihuman IgG antibody; matrix metalloproteinase; peptide microarray; poly(glycidyl methacrylate co 2 hydroxyethyl methacrylate) P(GMA HEMA); polymer brush substrate; protein microarray

Indexed keywords

ACRYLIC MONOMERS; ANTIBODIES; BINS; BIOCHEMISTRY; BIOCOMPATIBILITY; CHEMICAL DETECTION; COPOLYMERIZATION; DENDRIMERS; ENZYME ACTIVITY; FREE RADICAL REACTIONS; PEPTIDES; PHEMA; PROTEINS; SUBSTRATES;

HUMAN IGG; HYDROXYETHYL METHACRYLATE; MATRIX METALLOPROTEINASES; POLYMER BRUSHES; PROTEIN MICROARRAY;

ATOM TRANSFER RADICAL POLYMERIZATION;

2 HYDROXYETHYL METHACRYLATE; EPOXIDE; GLYCIDYL METHACRYLATE; METHACRYLIC ACID DERIVATIVE; PEPTIDE; PROTEIN BINDING;

HUMAN; PROTEIN MICROARRAY;

EPOXY COMPOUNDS; HUMANS; METHACRYLATES; PEPTIDES; PROTEIN ARRAY ANALYSIS; PROTEIN BINDING;

EID: 84966297159     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.6b01156     Document Type: Article

References (50)

1. Sassolas, A.; Leca-Bouvier, B. D.; Blum, L. J. DNA Biosensors and Microarrays Chem. Rev. 2008, 108, 109-139 10.1021/cr0684467
2. Weinrich, D.; Jonkheijm, P.; Niemeyer, C. M.; Waldmann, H. Applications of Protein Biochips in Biomedical and Biotechnological Research Angew. Chem., Int. Ed. 2009, 48, 7744-7751 10.1002/anie.200901480
3. Schutkowski, M.; Reimer, U.; Panse, S.; Dong, L.; Lizcano, J. M.; Alessi, D. R.; Schneider-Mergener, J. High-Content Peptide Microarrays for Deciphering Kinase Specificity and Biology Angew. Chem., Int. Ed. 2004, 43, 2671-2674 10.1002/anie.200453900
4. Wilson, D. S.; Nock, S. Recent Developments in Protein Microarray Technology Angew. Chem., Int. Ed. 2003, 42, 494-500 10.1002/anie.200390150
5. Köhn, M.; Gutierrez-Rodriguez, M.; Jonkheijm, P.; Wetzel, S.; Wacker, R.; Schroeder, H.; Prinz, H.; Niemeyer, C. M.; Breinbauer, R.; Szedlacsek, S. E.; Waldmann, H. A Microarray Strategy for Mapping the Substrate Specificity of Protein Tyrosine Phosphatase Angew. Chem., Int. Ed. 2007, 46, 7700-7703 10.1002/anie.200701601
6. Pirri, G.; Chiari, M.; Damin, F.; Meo, A. Microarray Glass Slides Coated with Block Copolymer Brushes Obtained by Reversible Addition Chain-Transfer Polymerization Anal. Chem. 2006, 78, 3118-3124 10.1021/ac0521091
7. Martin, K.; Steinberg, T. H.; Cooley, L. A.; Gee, K. R.; Beechem, J. M.; Patton, W. F. Quantitative Analysis of Protein Phosphorylation Status and Protein Kinase Activity on Microarrays Using a Novel Fluorescent Phosphorylation Sensor Dye Proteomics 2003, 3, 1244-1255 10.1002/pmic.200300445
8. MacBeath, G.; Schreiber, S. L. Printing Proteins as Microarrays for High-Throughput Function Determination Science 2000, 289, 1760-1763 10.1126/science.289.5485.1760
9. Haab, B.; Dunham, M.; Brown, P. Protein Microarrays for Highly Parallel Detection and Quantitation of Specific Proteins and Antibodies in Complex Solutions Genome Biol. 2001, 2, research0004.1-research0004.13 10.1186/gb-2001-2-2-research0004
10. Hong, B. J.; Oh, S. J.; Youn, T. O.; Kwon, S. H.; Park, J. W. Nanoscale-Controlled Spacing Provides DNA Microarrays with the SNP Discrimination Efficiency in Solution Phase Langmuir 2005, 21, 4257-4261 10.1021/la046951y
11. Lin, Z.; Ma, Y.; Zhao, C.; Chen, R.; Zhu, X.; Zhang, L.; Yan, X.; Yang, W. An Extremely Simple Method for Fabricating 3D Protein Microarrays with an Anti-Fouling Background and High Protein Capacity Lab Chip 2014, 14, 2505-2514 10.1039/c4lc00223g
12. Stillman, B. A.; Tonkinson, J. L. FAST Slides: A Novel Surface for Microarrays Biotechniques 2000, 29, 630-635
13. Allcock, H. R.; Phelps, M. V. B.; Barrett, E. W.; Pishko, M. V.; Koh, W.-G. Ultraviolet Photolithographic Development of Polyphosphazene Hydrogel Microstructures for Potential Use in Microarray Biosensors Chem. Mater. 2006, 18, 609-613 10.1021/cm050316b
14. Zhu, Y.; Gupta, B.; Guan, B.; Ciampi, S.; Reece, P. J.; Gooding, J. J. Photolithographic Strategy for Patterning Preformed, Chemically Modified, Porous Silicon Photonic Crystal Using Click Chemistry ACS Appl. Mater. Interfaces 2013, 5, 6514-6521 10.1021/am4006012
15. Krishnamoorthy, M.; Hakobyan, S.; Ramstedt, M.; Gautrot, J. E. Surface-Initiated Polymer Brushes in the Biomedical Field: Applications in Membrane Science, Biosensing, Cell Culture, Regenerative Medicine and Antibacterial Coatings Chem. Rev. 2014, 114, 10976-11026 10.1021/cr500252u
16. Barbey, R.; Lavanant, L.; Paripovic, D.; Schüwer, N.; Sugnaux, C.; Tugulu, S.; Klok, H.-A. Polymer Brushes via Surface-Initiated Controlled Radical Polymerization: Synthesis, Characterization, Properties, and Applications Chem. Rev. 2009, 109, 5437-5527 10.1021/cr900045a
17. Hucknall, A.; Kim, D.-H.; Rangarajan, S.; Hill, R. T.; Reichert, W. M.; Chilkoti, A. Simple Fabrication of Antibody Microarrays on Nonfouling Polymer Brushes with Femtomolar Sensitivity for Protein Analytes in Serum and Blood Adv. Mater. 2009, 21, 1968-1971 10.1002/adma.200803125
18. Ma, J.; Luan, S.; Song, L.; Yuan, S.; Yan, S.; Jin, J.; Yin, J. Facile Fabrication of Microsphere-Polymer Brush Hierarchically Three-Dimensional (3D) Substrates for Immunoassays Chem. Commun. 2015, 51, 6749-6752 10.1039/C5CC01250C
19. Bilgic, T.; Klok, H.-A. Oligonucleotide Immobilization and Hybridization on Aldehyde-Functionalized Poly(2-hydroxyethyl methacrylate) Brushes Biomacromolecules 2015, 16, 3657-3665 10.1021/acs.biomac.5b01116
20. Liu, W.; Liu, X.; Ge, P.; Fang, L.; Xiang, S.; Zhao, X.; Shen, H.; Yang, B. Hierarchical-Multiplex DNA Patterns Mediated by Polymer Brush Nanocone Arrays That Possess Potential Application for Specific DNA Sensing ACS Appl. Mater. Interfaces 2015, 7, 24760-24771 10.1021/acsami.5b07577
21. Hu, W.; Li, X.; He, G.; Zhang, Z.; Zheng, X.; Li, P.; Li, C. M. Sensitive Competitive Immunoassay of Multiple Mycotoxins with Non-Fouling Antigen Microarray Biosens. Bioelectron. 2013, 50, 338-344 10.1016/j.bios.2013.06.037
22. Barbey, R.; Kauffmann, E.; Ehrat, M.; Klok, H.-A. Protein Microarrays Based on Polymer Brushes Prepared via Surface-Initiated Atom Transfer Radical Polymerization Biomacromolecules 2010, 11, 3467-3479 10.1021/bm101297w
23. Salisbury, C. M.; Maly, D. J.; Ellman, J. A. Peptide Microarrays for the Determination of Protease Substrate Specificity J. Am. Chem. Soc. 2002, 124, 14868-14870 10.1021/ja027477q
24. Zhang, D.; Kilian, K. A. Peptide Microarrays for the Discovery of Bioactive Surfaces That Guide Cellular Processes: A Single Step Azide-Alkyne 'Click' Chemistry Approach J. Mater. Chem. B 2014, 2, 4280-4288 10.1039/C4TB00375F
25. Hu, W.; Liu, Y.; Lu, Z.; Li, C. M. Poly[oligo(ethylene glycol) methacrylate-co-glycidyl methacrylate] Brush Substrate for Sensitive Surface Plasmon Resonance Imaging Protein Arrays Adv. Funct. Mater. 2010, 20, 3497-3503 10.1002/adfm.201001159
26. Gao, J.; Liu, C.; Liu, D.; Wang, Z.; Dong, S. Antibody Microarray-Based Strategies for Detection of Bacteria by Lectin-Conjugated Gold Nanoparticle Probes Talanta 2010, 81, 1816-1820 10.1016/j.talanta.2010.03.052
27. Li, T.; Liu, D.; Wang, Z. Screening Kinase Inhibitors with a Microarray-Based Fluorescent and Resonance Light Scattering Assay Anal. Chem. 2010, 82, 3067-3072 10.1021/ac902804h
28. Lei, Z.; Gao, J.; Liu, X.; Liu, D.; Wang, Z. Peptide Microarray-Based Fluorescence Assay for Simultaneously Detecting Matrix Metalloproteinases Anal. Methods 2016, 8, 72-77 10.1039/C5AY02041G
29. Jones, D. M.; Huck, W. T. S. Controlled Surface-Initiated Polymerizations in Aqueous Media Adv. Mater. 2001, 13, 1256-1259 10.1002/1521-4095(200108)13:16<1256::AID-ADMA1256>3.0.CO;2-B
30. Chan, K.; Gleason, K. K. Initiated Chemical Vapor Deposition of Linear and Cross-linked Poly(2-hydroxyethyl methacrylate) for Use as Thin-Film Hydrogels Langmuir 2005, 21, 8930-8939 10.1021/la051004q
31. Barbey, R.; Laporte, V.; Alnabulsi, S.; Klok, H.-A. Postpolymerization Modification of Poly(glycidyl methacrylate) Brushes: An XPS Depth-Profiling Study Macromolecules 2013, 46, 6151-6158 10.1021/ma400819a
32. Barbey, R.; Klok, H.-A. Room Temperature, Aqueous Post-Polymerization Modification of Glycidyl Methacrylate-Containing Polymer Brushes Prepared via Surface-Initiated Atom Transfer Radical Polymerization Langmuir 2010, 26, 18219-18230 10.1021/la102400z
33. Nagase, H.; Woessner, J. F. Matrix Metalloproteinases J. Biol. Chem. 1999, 274, 21491-21494 10.1074/jbc.274.31.21491
34. Zitka, O.; Kukacka, J.; Krizkov, S.; Huska, D.; Adam, V.; Masarik, M.; Prusa, R.; Kizek, R. Matrix Metalloproteinases Curr. Med. Chem. 2010, 17, 3751-3768 10.2174/092986710793213724
35. Murphy, G.; Nagase, H. Progress in Matrix Metalloproteinase Research Mol. Aspects Med. 2008, 29, 290-308 10.1016/j.mam.2008.05.002
36. Deryugina, E.; Quigley, J. Matrix Metalloproteinases and Tumor Metastasis Cancer Metastasis Rev. 2006, 25, 9-34 10.1007/s10555-006-7886-9
37. Kridel, S. J.; Chen, E.; Kotra, L. P.; Howard, E. W.; Mobashery, S.; Smith, J. W. Substrate Hydrolysis by Matrix Metalloproteinase-9 J. Biol. Chem. 2001, 276, 20572-20578 10.1074/jbc.M100900200
38. Fudala, R.; Ranjan, A. P.; Mukerjee, A.; Vishwanatha, J. K.; Gryczynski, Z.; Borejdo, J.; Sarkar, P.; Gryczynski, I. Fluorescence Detection of MMP-9. I. MMP-9 Selectively Cleaves Lys-Gly-Pro-Arg-Ser-Leu-Ser-Gly-Lys Peptide Curr. Pharm. Biotechnol. 2011, 12, 834-838 10.2174/138920111795470967
39. Fudala, R.; Rich, R.; Mukerjee, A.; Ranjan, A. P.; Vishwanatha, J. K.; Kurdowska, A. K.; Gryczynski, Z.; Borejdo, J.; Gryczynski, I. Fluorescence Detection of MMP-9. II. Ratiometric FRET-Based Sensing with Dually Labeled Specific Peptide Curr. Pharm. Biotechnol. 2013, 14, 1134-1138 10.2174/138920101413140605111109
40. Wang, Y.; Shen, P.; Li, C.; Wang, Y.; Liu, Z. Upconversion Fluorescence Resonance Energy Transfer Based Biosensor for Ultrasensitive Detection of Matrix Metalloproteinase-2 in Blood Anal. Chem. 2012, 84, 1466-1473 10.1021/ac202627b
41. Wang, Z.; Li, X.; Feng, D.; Li, L.; Shi, W.; Ma, H. Poly(m-phenylenediamine)-Based Fluorescent Nanoprobe for Ultrasensitive Detection of Matrix Metalloproteinase 2 Anal. Chem. 2014, 86, 7719-7725 10.1021/ac5016563
42. Lefkowitz, R. B.; Schmid-Schönbein, G. W.; Heller, M. J. Whole Blood Assay for Elastase, Chymotrypsin, Matrix Metalloproteinase-2, and Matrix Metalloproteinase-9 Activity Anal. Chem. 2010, 82, 8251-8258 10.1021/ac101462c
43. Jung, S.-H.; Kong, D.-H.; Park, J. H.; Lee, S.-T.; Hyun, J.; Kim, Y.-M.; Ha, K.-S. Rapid Analysis of Matrix Metalloproteinase-3 Activity by Gelatin Arrays Using a Spectral Surface Plasmon Resonance Biosensor Analyst 2010, 135, 1050-1057 10.1039/b919857a
44. Bolduc, O. R.; Pelletier, J. N.; Masson, J.-F. SPR Biosensing in Crude Serum Using Ultralow Fouling Binary Patterned Peptide SAM Anal. Chem. 2010, 82, 3699-3706 10.1021/ac100035s
45. Shoji, A.; Kabeya, M.; Sugawara, M. Real-Time Monitoring of Matrix Metalloproteinase-9 Collagenolytic Activity with a Surface Plasmon Resonance Biosensor Anal. Biochem. 2011, 419, 53-60 10.1016/j.ab.2011.07.031
46. Roomi, M.; Monterrey, J.; Kalinovsky, T.; Rath, M.; Niedzwiecki, A. Patterns of MMP-2 and MMP-9 Expression in Human Cancer Cell Lines Oncol. Rep. 2009, 21, 1323-1333 10.3892/or-00000358
47. Li, X.; Deng, D.; Xue, J.; Qu, L.; Achilefu, S.; Gu, Y. Quantum Dots Based Molecular Beacons for in Vitro and in Vivo Detection of MMP-2 on Tumor Biosens. Bioelectron. 2014, 61, 512-518 10.1016/j.bios.2014.05.035
48. Ling, H.; Yang, H.; Tan, S. H.; Chui, W. K.; Chew, E. H. 6-Shogaol, an Active Constituent of Ginger, Inhibits Breast Cancer Cell Invasion by Reducing Matrix Metalloproteinase-9 Expression via Blockade of Nuclear Factor-κB Activation Br. J. Pharmacol. 2010, 161, 1763-1777 10.1111/j.1476-5381.2010.00991.x
49. Bachmeier, B. E.; Albini, A.; Vené, R.; Benelli, R.; Noonan, D.; Weigert, C.; Weiler, C.; Lichtinghagen, R.; Jochum, M.; Nerlich, A. G. Cell Density-Dependent Regulation of Matrix Metalloproteinase and TIMP Expression in Differently Tumorigenic Breast Cancer Cell Lines Exp. Cell Res. 2005, 305, 83-98 10.1016/j.yexcr.2004.12.019
50. Tugulu, S.; Silacci, P.; Stergiopulos, N.; Klok, H.-A. RGD-Functionalized Polymer Brushes as Substrates for the Integrin Specific Adhesion of Human Umbilical Vein Endothelial Cells Biomaterials 2007, 28, 2536-2546 10.1016/j.biomaterials.2007.02.006