PCSK9 inhibition in the management of hyperlipidemia: Focus on evolocumab

Vascular Health and Risk Management

Volumn 12, Issue , 2016, Pages 185-197

  Blom, Dirk J ^a   Dent, Ricardo ^b   Castro, Rita C ^b   Toth, Peter P ^c,d  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b AMGEN INC   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CGH Medical Center   (United States)

Author keywords

Alirocumab; Hypercholesterolemia; Hyperlipidemia; LDL C; Monoclonal antibody

Indexed keywords

ALIROCUMAB; ATORVASTATIN; EVOLOCUMAB; EZETIMIBE; GLYCOSYLATED HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPOPROTEIN; MONOCLONAL ANTIBODY; PROTEIN PCSK9; SERINE PROTEINASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ANTILIPEMIC AGENT; BIOLOGICAL MARKER; LIPID; PCSK9 PROTEIN, HUMAN; PROPROTEIN CONVERTASE 9; SERINE PROTEINASE INHIBITOR;

ANTIHYPERLIPIDEMIC ACTIVITY; ARTICLE; BACKACHE; BRONCHITIS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RESPONSE; CLINICAL PRACTICE; CLINICAL TRIAL (TOPIC); COMBINATION CHEMOTHERAPY; COUGHING; DIARRHEA; DISORDERS OF HIGHER CEREBRAL FUNCTION; DIZZINESS; DRUG ACTIVITY; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ENZYME INHIBITION; FAMILIAL HYPERCHOLESTEROLEMIA; GASTROENTERITIS; HEADACHE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIA; HYPERTENSION; INFLUENZA; INJECTION SITE REACTION; LONG TERM CARE; MONOTHERAPY; MUSCLE SPASM; MUSCULOSKELETAL PAIN; MYALGIA; OUTCOME ASSESSMENT; PATIENT CARE; PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PRIMARY MEDICAL CARE; RHINOPHARYNGITIS; SIDE EFFECT; SINUSITIS; UPPER RESPIRATORY TRACT INFECTION; URINARY TRACT INFECTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; CARDIOVASCULAR DISEASES; COMPLICATION; ENZYMOLOGY; HYPERLIPIDEMIAS; METABOLISM; RISK FACTOR; TIME FACTOR; TREATMENT OUTCOME;

ANIMALS; ANTIBODIES, MONOCLONAL; BIOMARKERS; CARDIOVASCULAR DISEASES; HUMANS; HYPERLIPIDEMIAS; HYPOLIPIDEMIC AGENTS; LIPIDS; PROPROTEIN CONVERTASE 9; RISK FACTORS; SERINE PROTEINASE INHIBITORS; TIME FACTORS; TREATMENT OUTCOME;

EID: 84966293831     PISSN: 11766344     EISSN: 11782048     Source Type: Journal    
DOI: 10.2147/VHRM.S102564     Document Type: Article

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