Increased level of H19 long noncoding RNA promotes invasion, angiogenesis, and stemness of glioblastoma cells

Journal of Neurosurgery

Volumn 124, Issue 1, 2016, Pages 129-136

  Jiang, Xiaochun ^a   Yan, Yukui ^b   Hu, Minghua ^a   Chen, Xiande ^a   Wang, Yaxian ^b   Dai, Yi ^a   Wu, Degang ^a   Wang, Yongsheng ^c   Zhuang, Zhixiang ^d   Xia, Hongping ^a  

^a WANNAN MEDICAL COLLEGE   (China)

^b HUZHOU CENTRAL HOSPITAL   (China)

^c MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^d SUZHOU UNIVERSITY   (China)

Author keywords

Angiogenesis; Glioblastoma; H19; Invasion; Long noncoding RNA; Mouse; Oncology; Stemness

Indexed keywords

CD133 ANTIGEN; LONG UNTRANSLATED RNA; RNA H19; GLYCOPROTEIN; H19 LONG NON-CODING RNA; LEUKOCYTE ANTIGEN; PEPTIDE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CANCER SURGERY; CANCER SURVIVAL; CARCINOGENESIS; CARCINOGENICITY; CELL INVASION; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; GLIOMA STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SURVIVAL ANALYSIS; TUMOR GROWTH; TUMOR INVASION; TUMOR VOLUME; TUMOR XENOGRAFT; ANIMAL; BAGG ALBINO MOUSE; BRAIN TUMOR; CANCER STEM CELL; CELL CLONE; DRUG SCREENING; GENETICS; MORTALITY; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; TUMOR CELL LINE; CASE CONTROL STUDY; CELL CULTURE TECHNIQUE; DISEASE MODEL; MALE; METABOLISM;

ANIMALS; ANTIGENS, CD; BRAIN NEOPLASMS; CELL LINE, TUMOR; CLONE CELLS; FEMALE; GLIOBLASTOMA; GLYCOPROTEINS; HUMANS; MICE; MICE, INBRED BALB C; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; NEOVASCULARIZATION, PATHOLOGIC; PEPTIDES; RNA, LONG NONCODING; SURVIVAL ANALYSIS; XENOGRAFT MODEL ANTITUMOR ASSAYS; CASE-CONTROL STUDIES; CELL CULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; MALE; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84966277157     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2014.12.JNS1426     Document Type: Article

References (31)

1. Amit D, Hochberg A: Development of targeted therapy for a broad spectrum of cancers (pancreatic cancer, ovarian cancer, glioblastoma and HCC) mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences. Int J Clin Exp Med 5:296-305, 2012
2. Amit D, Matouk IJ, Lavon I, Birman T, Galula J, Abu-Lail R, et al: Transcriptional targeting of glioblastoma by diphtheria toxin-A driven by both H19 and IGF2-P4 promoters. Int J Clin Exp Med 5:124-135, 2012
3. Ayers D: Long non-coding RNAs: novel emergent biomarkers for cancer diagnostics. J Cancer Res Treatment 1:31-35, 2013
4. Barsyte-Lovejoy D, Lau SK, Boutros PC, Khosravi F, Jurisica I, Andrulis IL, et al: The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis. Cancer Res 66:5330-5337, 2006
5. Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, et al: The somatic genomic landscape of glioblastoma. Cell 155:462-477, 2013
6. Esteller M: Non-coding RNAs in human disease. Nat Rev Genet 12:861-874, 2011
7. Fellig Y, Amit D, Matouk IJ, Kopolovic J, Erdmann VA, Hochberg A: The non-coding oncofetal H19 gene in brain tumors, in Erdmann VA, Reifenberger G, Barciszewski HJ (eds): Therapeutic Ribonucleic Acids in Brain Tumors. Berlin: Springer, 2009, pp 471-484
8. Frattini V, Trifonov V, Chan JM, Castano A, Lia M, Abate F, et al: The integrated landscape of driver genomic alterations in glioblastoma. Nat Genet 45:1141-1149, 2013
9. Han L, Zhang K, Shi Z, Zhang J, Zhu J, Zhu S, et al: LncRNA proo le of glioblastoma reveals the potential role of lncRNAs in contributing to glioblastoma pathogenesis. Int J Oncol 40:2004-2012, 2012
10. Hao Y, Crenshaw T, Moulton T, Newcomb E, Tycko B: Tumour- suppressor activity of H19 RNA. Nature 365:764-767, 1993
11. Hauptman N, Glavač D: Long non-coding RNA in cancer. Int J Mol Sci 14:4655-4669, 2013
12. He Y, Meng XM, Huang C, Wu BM, Zhang L, Lv XW, et al: Long noncoding RNAs: Novel insights into hepatocelluar carcinoma. Cancer Lett 344:20-27, 2014
13. Iizuka N, Oka M, Tamesa T, Hamamoto Y, Yamada-Okabe H: Imbalance in expression levels of insulin-like growth factor 2 and H19 transcripts linked to progression of hepatocellular carcinoma. Anticancer Res 24:4085-4089, 2004
14. Kotliarova S, Fine HA: SnapShot: glioblastoma multiforme. Cancer Cell 21:710.e1, 2012
15. Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔC T method. Methods 25:402-408, 2001
16. Luo M, Li Z, Wang W, Zeng Y, Liu Z, Qiu J: Long noncoding RNA H19 increases bladder cancer metastasis by associating with EZH2 and inhibiting E-cadherin expression. Cancer Lett 333:213-221, 2013
17. Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, et al: Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350:2129-2139, 2004
18. Matouk I, Ohana P, Ayesh S, Sidi A, Czerniak A, de Groot N, et al: The oncofetal H19 RNA in human cancer, from the bench to the patient. Cancer Ther 3:249-266, 2005
19. Matouk IJ, DeGroot N, Mezan S, Ayesh S, Abu-lail R, Hochberg A, et al: The H19 non-coding RNA is essential for human tumor growth. PLoS ONE 2:e845, 2007
20. Cancer Genome Atlas Research Network: Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455:1061-1068, 2008
21. Omuro A, DeAngelis LM: Glioblastoma and other malignant gliomas: a clinical review. JAMA 310:1842-1850, 2013
22. Park JY, Lee JE, Park JB, Yoo H, Lee SH, Kim JH: Roles of long non-coding RNAs on tumorigenesis and glioma development. Brain Tumor Res Treat 2:1-6, 2014
23. Parsons DW, Jones S, Zhang X, Lin JCH, Leary RJ, Angenendt P, et al: An integrated genomic analysis of human glioblastoma multiforme. Science 321:1807-1812, 2008
24. Qiu MT, Hu JW, Yin R, Xu L: Long noncoding RNA: an emerging paradigm of cancer research. Tumour Biol 34:613-620, 2013
25. Song H, Sun W, Ye G, Ding X, Liu Z, Zhang S, et al: Long non-coding RNA expression profile in human gastric cancer and its clinical significances. J Transl Med 11:225, 2013
26. Tate MC, Aghi MK: Biology of angiogenesis and invasion in glioma. Neurotherapeutics 6:447-457, 2009
27. Wörns MA, Galle PR: HCC therapies-lessons learned. Nat Rev Gastroenterol Hepatol 11:447-452, 2014
28. Xia H, Cheung WK, Ng SS, Jiang X, Jiang S, Sze J, et al: Loss of brain-enriched miR-124 microRNA enhances stemlike traits and invasiveness of glioma cells. J Biol Chem 287:9962-9971, 2012
29. Xia H, Yan Y, Hu M, Wang Y, Wang Y, Dai Y, et al: MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-kB activity. Neuro Oncol 15:413-422, 2012
30. Yang F, Bi J, Xue X, Zheng L, Zhi K, Hua J, et al: Up-regulated long non-coding RNA H19 contributes to proliferation of gastric cancer cells. FEBS J 279:3159-3165, 2012
31. Zhang Y, Tycko B: Monoallelic expression of the human H19 gene. Nat Genet 1:40-44, 1992