메뉴 건너뛰기




Volumn 5, Issue 4, 2012, Pages 296-305

Development of targeted therapy for a broad spectrum of cancers (pancreatic cancer, ovarian cancer, glioblastoma and HCC) mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences

Author keywords

Diphtheria toxin A; Glioblastoma; H19; Hepatocellular carcinoma; IGF2; Ovarian cancer; Pancreatic cancer; Targeted cancer therapy

Indexed keywords

ANTINEOPLASTIC AGENT; DIPHTHERIA TOXIN A FRAGMENT; UNCLASSIFIED DRUG;

EID: 84866016111     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (40)

References (44)
  • 12
    • 0023730194 scopus 로고
    • Differential expression of the human insulinlike growth factor II gene. Characterization of the IGF-II mRNAs and an mRNA encoding a putative IGF-II-associated protein
    • de Pagter-Holthuizen P, Jansen M, van der Kammen RA, van Schaik FM and Sussenbach JS. Differential expression of the human insulinlike growth factor II gene. Characterization of the IGF-II mRNAs and an mRNA encoding a putative IGF-II-associated protein. Biochim Biophys Acta 1988; 950: 282-295.
    • (1988) Biochim Biophys Acta , vol.950 , pp. 282-295
    • de Pagter-Holthuizen, P.1    Jansen, M.2    van der Kammen, R.A.3    van Schaik, F.M.4    Sussenbach, J.S.5
  • 13
    • 0025086209 scopus 로고
    • Identification and initial characterization of a fourth leader exon and promoter of the human IGF-II gene
    • Holthuizen P, van der Lee FM, Ikejiri K, Yamamoto M and Sussenbach JS. Identification and initial characterization of a fourth leader exon and promoter of the human IGF-II gene. Biochim Biophys Acta 1990; 1087: 341-343.
    • (1990) Biochim Biophys Acta , vol.1087 , pp. 341-343
    • Holthuizen, P.1    van der Lee, F.M.2    Ikejiri, K.3    Yamamoto, M.4    Sussenbach, J.S.5
  • 14
    • 0028899741 scopus 로고
    • Promoter-specific IGF2 imprinting status and its plasticity during human liver development
    • Ekstrom TJ, Cui H, Li X and Ohlsson R. Promoter-specific IGF2 imprinting status and its plasticity during human liver development. Development 1995; 121: 309-316.
    • (1995) Development , vol.121 , pp. 309-316
    • Ekstrom, T.J.1    Cui, H.2    Li, X.3    Ohlsson, R.4
  • 16
    • 0029556759 scopus 로고
    • Normal development and neoplasia: The imprinting connection
    • Ohlsson R and Franklin G. Normal development and neoplasia: the imprinting connection. Int J Dev Biol 1995; 39: 869-876.
    • (1995) Int J Dev Biol , vol.39 , pp. 869-876
    • Ohlsson, R.1    Franklin, G.2
  • 17
    • 0031956224 scopus 로고    scopus 로고
    • Insulin-like growth factor 2 and overgrowth: Molecular biology and clinical implications
    • Morison IM and Reeve AE. Insulin-like growth factor 2 and overgrowth: molecular biology and clinical implications. Mol Med Today 1998; 4: 110-115.
    • (1998) Mol Med Today , vol.4 , pp. 110-115
    • Morison, I.M.1    Reeve, A.E.2
  • 18
    • 0031560899 scopus 로고    scopus 로고
    • Relaxation of imprinting of human insulinlike growth factor II gene, IGF2, in sporadic breast carcinomas
    • Wu HK, Squire JA, Catzavelos CG and Weksberg R. Relaxation of imprinting of human insulinlike growth factor II gene, IGF2, in sporadic breast carcinomas. Biochem Biophys Res Commun 1997; 235: 123-129.
    • (1997) Biochem Biophys Res Commun , vol.235 , pp. 123-129
    • Wu, H.K.1    Squire, J.A.2    Catzavelos, C.G.3    Weksberg, R.4
  • 21
    • 0034708052 scopus 로고    scopus 로고
    • Promoter usage for insulin-like growth factor-II in cancerous and benign human breast, prostate, and bladder tissues, and confirmation of a 10th exon
    • Mineo R, Fichera E, Liang SJ and Fujita-Yamaguchi Y. Promoter usage for insulin-like growth factor-II in cancerous and benign human breast, prostate, and bladder tissues, and confirmation of a 10th exon. Biochem Biophys Res Commun 2000; 268: 886-892.
    • (2000) Biochem Biophys Res Commun , vol.268 , pp. 886-892
    • Mineo, R.1    Fichera, E.2    Liang, S.J.3    Fujita-Yamaguchi, Y.4
  • 22
    • 0029840654 scopus 로고    scopus 로고
    • Increased expression of insulin-like growth factor 2 in hepatocellular carcinoma is primarily regulated at the transcriptional level
    • Sohda T, Yun K, Iwata K, Soejima H and Okumura M. Increased expression of insulin-like growth factor 2 in hepatocellular carcinoma is primarily regulated at the transcriptional level. Lab Invest 1996; 75: 307-311.
    • (1996) Lab Invest , vol.75 , pp. 307-311
    • Sohda, T.1    Yun, K.2    Iwata, K.3    Soejima, H.4    Okumura, M.5
  • 25
    • 78650102883 scopus 로고    scopus 로고
    • Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences
    • Amit D and Hochberg A. Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences. J Transl Med 2010; 8: 134.
    • (2010) J Transl Med , vol.8 , pp. 134
    • Amit, D.1    Hochberg, A.2
  • 27
    • 0037112364 scopus 로고    scopus 로고
    • Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2
    • Cui H, Onyango P, Brandenburg S, Wu Y, Hsieh CL and Feinberg AP. Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2. Cancer Res 2002; 62: 6442-6446.
    • (2002) Cancer Res , vol.62 , pp. 6442-6446
    • Cui, H.1    Onyango, P.2    Brandenburg, S.3    Wu, Y.4    Hsieh, C.L.5    Feinberg, A.P.6
  • 28
    • 0037381304 scopus 로고    scopus 로고
    • Monoallelic upregulation of the imprinted H19 gene in airway epithelium of phenotypically normal cigarette smokers
    • Kaplan R, Luettich K, Heguy A, Hackett NR, Harvey BG and Crystal RG. Monoallelic upregulation of the imprinted H19 gene in airway epithelium of phenotypically normal cigarette smokers. Cancer Res 2003; 63: 1475-1482.
    • (2003) Cancer Res , vol.63 , pp. 1475-1482
    • Kaplan, R.1    Luettich, K.2    Heguy, A.3    Hackett, N.R.4    Harvey, B.G.5    Crystal, R.G.6
  • 31
    • 0037000488 scopus 로고    scopus 로고
    • The role of insulin-like growth factor 2 and its receptors in human tumors
    • Pavelic K, Bukovic D and Pavelic J. The role of insulin-like growth factor 2 and its receptors in human tumors. Mol Med 2002; 8: 771-780.
    • (2002) Mol Med , vol.8 , pp. 771-780
    • Pavelic, K.1    Bukovic, D.2    Pavelic, J.3
  • 32
    • 0028880017 scopus 로고
    • Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II)
    • Bates P, Fisher R, Ward A, Richardson L, Hill DJ and Graham CF. Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II). Br J Cancer 1995; 72: 1189-1193.
    • (1995) Br J Cancer , vol.72 , pp. 1189-1193
    • Bates, P.1    Fisher, R.2    Ward, A.3    Richardson, L.4    Hill, D.J.5    Graham, C.F.6
  • 33
    • 0037434663 scopus 로고    scopus 로고
    • Transgenic overexpression of IGF-II induces spontaneous lung tumors: A model for human lung adenocarcinoma
    • Moorehead RA, Sanchez OH, Baldwin RM and Khokha R. Transgenic overexpression of IGF-II induces spontaneous lung tumors: a model for human lung adenocarcinoma. Oncogene 2003; 22: 853-857.
    • (2003) Oncogene , vol.22 , pp. 853-857
    • Moorehead, R.A.1    Sanchez, O.H.2    Baldwin, R.M.3    Khokha, R.4
  • 34
    • 0028318189 scopus 로고
    • Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice
    • Rogler CE, Yang D, Rossetti L, Donohoe J, Alt E, Chang CJ, Rosenfeld R, Neely K and Hintz R. Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice. J Biol Chem 1994; 269: 13779-13784.
    • (1994) J Biol Chem , vol.269 , pp. 13779-13784
    • Rogler, C.E.1    Yang, D.2    Rossetti, L.3    Donohoe, J.4    Alt, E.5    Chang, C.J.6    Rosenfeld, R.7    Neely, K.8    Hintz, R.9
  • 35
    • 0031965821 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor-2 can predict the prognosis of human colorectal cancer patients: Correlation with tumor progression, proliferative activity and survival
    • Kawamoto K, Onodera H, Kondo S, Kan S, Ikeuchi D, Maetani S and Imamura M. Expression of insulin-like growth factor-2 can predict the prognosis of human colorectal cancer patients: correlation with tumor progression, proliferative activity and survival. Oncology 1998; 55: 242-248.
    • (1998) Oncology , vol.55 , pp. 242-248
    • Kawamoto, K.1    Onodera, H.2    Kondo, S.3    Kan, S.4    Ikeuchi, D.5    Maetani, S.6    Imamura, M.7
  • 37
    • 0028356419 scopus 로고
    • A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis
    • Christofori G, Naik P and Hanahan D. A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis. Nature 1994; 369: 414-418.
    • (1994) Nature , vol.369 , pp. 414-418
    • Christofori, G.1    Naik, P.2    Hanahan, D.3
  • 40
    • 0034692430 scopus 로고    scopus 로고
    • Role of the insulin-like growth factor family in cancer development and progression
    • Yu H and Rohan T. Role of the insulin-like growth factor family in cancer development and progression. J Natl Cancer Inst 2000; 92: 1472-1489.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1472-1489
    • Yu, H.1    Rohan, T.2
  • 42
    • 0033897718 scopus 로고    scopus 로고
    • A quantitative reverse transcription and polymerase chain reaction assay for human IGF-II allows direct comparison of IGF-II mRNA levels in cancerous breast, bladder, and prostate tissues
    • Fichera E, Liang S, Xu Z, Guo N, Mineo R and Fujita-Yamaguchi Y. A quantitative reverse transcription and polymerase chain reaction assay for human IGF-II allows direct comparison of IGF-II mRNA levels in cancerous breast, bladder, and prostate tissues. Growth Horm IGF Res 2000; 10: 61-70.
    • (2000) Growth Horm IGF Res , vol.10 , pp. 61-70
    • Fichera, E.1    Liang, S.2    Xu, Z.3    Guo, N.4    Mineo, R.5    Fujita-Yamaguchi, Y.6
  • 43
    • 0032893137 scopus 로고    scopus 로고
    • Possible paracrine mechanism of insulin-like growth factor-2 in the development of liver metastases from colorectal carcinoma
    • Kawamoto K, Onodera H, Kan S, Kondo S and Imamura M. Possible paracrine mechanism of insulin-like growth factor-2 in the development of liver metastases from colorectal carcinoma. Cancer 1999; 85: 18-25.
    • (1999) Cancer , vol.85 , pp. 18-25
    • Kawamoto, K.1    Onodera, H.2    Kan, S.3    Kondo, S.4    Imamura, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.