Layer-by-layer assembled fluorescent probes in the second near-infrared window for systemic delivery and detection of ovarian cancer

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 19, 2016, Pages 5179-5184

  Dang, Xiangnan ^a,b   Gu, Li ^a,b   Qi, Jifa ^a,b   Correa, Santiago ^a,b   Zhang, Geran ^a,b   Belcher, Angela M ^a,b   Hammond, Paula T ^a,b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Massachusetts Institute of Technology   (United States)

Author keywords

Deep penetration; Layer by layer; Ovarian tumor detection; Second near infrared window; Systemic comparison

Indexed keywords

FLUORESCENT DYE; LANTHANIDE; QUANTUM DOT; SINGLE WALLED NANOTUBE; SMALL INTERFERING RNA; CONTRAST MEDIUM; NANOCAPSULE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER DIAGNOSIS; CIRCULATION; FEMALE; FLUORESCENCE IMAGING; LAYER BY LAYER ASSEMBLY; MOUSE; NONHUMAN; OVARY CANCER; PLASMA HALF LIFE; PRIORITY JOURNAL; SECOND NEAR INFRARED WINDOW; SIGNAL NOISE RATIO; SURFACE CHARGE; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; ANTIBODY SPECIFICITY; BAGG ALBINO MOUSE; CHEMISTRY; CRYSTALLIZATION; DIAGNOSTIC IMAGING; FLUORESCENCE MICROSCOPY; HUMAN; NEAR INFRARED SPECTROSCOPY; OVARY TUMOR; PATHOLOGY; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SYNTHESIS; THERANOSTIC NANOMEDICINE; TISSUE DISTRIBUTION; TUMOR CELL LINE; ULTRASTRUCTURE;

ANIMALS; CELL LINE, TUMOR; CONTRAST MEDIA; CRYSTALLIZATION; FEMALE; FLUORESCENT DYES; HUMANS; MICE; MICE, INBRED BALB C; MICROSCOPY, FLUORESCENCE; NANOCAPSULES; ORGAN SPECIFICITY; OVARIAN NEOPLASMS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROSCOPY, NEAR-INFRARED; THERANOSTIC NANOMEDICINE; TISSUE DISTRIBUTION;

EID: 84966277141     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1521175113     Document Type: Article

References (43)

1. Jung HK, Wang K, Jung MK, Kim IS, Lee BH (2014) In vivo near-infrared fluorescence imaging of apoptosis using histone H1-targeting peptide probe after anti-cancer treatment with cisplatin and cetuximab for early decision on tumor response. PLoS One 9(6):e100341.
2. van Dam GM, et al. (2011) Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor - a targeting: First in-human results. Nat Med 17(10):1315-1319.
3. Zhang X, et al. (2015) Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer's disease. Proc Natl Acad Sci USA 112(31):9734-9739.
4. Zhu A, et al. (2015) Dually pH/reduction-responsive vesicles for ultrahigh-contrast fluorescence imaging and thermo-chemotherapy-synergized tumor ablation. ACS Nano 9(8):7874-7885.
5. Weissleder R, Pittet MJ (2008) Imaging in the era of molecular oncology. Nature 452(7187):580-589.
6. Hong G, et al. (2012) Multifunctional in vivo vascular imaging using near-infrared II fluorescence. Nat Med 18(12):1841-1846.
7. Ghosh D, et al. (2014) Deep, noninvasive imaging and surgical guidance of submillimeter tumors using targeted M13-stabilized single-walled carbon nanotubes. Proc Natl Acad Sci USA 111(38):13948-13953.
8. Hong G, et al. (2012) In vivo fluorescence imaging with Ag2S quantum dots in the second near-infrared region. Angew Chem Int Ed Engl 51(39):9818-9821.
9. Naczynski DJ, et al. (2013) Rare-earth-doped biological composites as in vivo shortwave infrared reporters. Nat Commun 4:2199.
10. Tao Z, et al. (2013) Biological imaging using nanoparticles of small organic molecules with fluorescence emission at wavelengths longer than 1000 nm. Angew Chem Int Ed Engl 52(49):13002-13006.
11. Yi H, et al. (2012) M13 phage-functionalized single-walled carbon nanotubes as nanoprobes for second near-infrared window fluorescence imaging of targeted tumors. Nano Lett 12(3):1176-1183.
12. Diao S, et al. (2015) Fluorescence imaging in vivo at wavelengths beyond 1500 nm. Angew Chem Int Ed Engl 54(49):14758-14762.
13. Deng ZJ, et al. (2013) Layer-by-layer nanoparticles for systemic codelivery of an anticancer drug and siRNA for potential triple-negative breast cancer treatment. ACS Nano 7(11):9571-9584.
14. Dreaden EC, et al. (2014) Bimodal tumor-targeting from microenvironment responsive hyaluronan layer-by-layer (LbL) nanoparticles. ACS Nano 8(8):8374-8382.
15. Poon Z, Lee JB, Morton SW, Hammond PT (2011) Controlling in vivo stability and biodistribution in electrostatically assembled nanoparticles for systemic delivery. Nano Lett 11(5):2096-2103.
16. Elbakry A, et al. (2009) Layer-by-layer assembled gold nanoparticles for siRNA delivery. Nano Lett 9(5):2059-2064.
17. Dreaden EC, et al. (2015) Tumor-targeted synergistic blockade of MAPK and PI3K from a layer-by-layer nanoparticle. Clin Cancer Res 21(19):4410-4419.
18. Schneider G, Decher G (2004) From functional core/shell nanoparticles prepared via layer-by-layer deposition to empty nanospheres. Nano Lett 4(10):1833-1839.
19. Ai H (2011) Layer-by-layer capsules for magnetic resonance imaging and drug delivery. Adv Drug Deliv Rev 63(9):772-788.
20. Soike T, et al. (2010) Engineering a material surface for drug delivery and imaging using layer-by-layer assembly of functionalized nanoparticles. Adv Mater 22(12):1392-1397.
21. Liu Z, et al. (2008) Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy. Proc Natl Acad Sci USA 105(5):1410-1415.
22. Blanco E, Shen H, Ferrari M (2015) Principles of nanoparticle design for overcoming biological barriers to drug delivery. Nat Biotechnol 33(9):941-951.
23. Alexis F, Pridgen E, Molnar LK, Farokhzad OC (2008) Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol Pharm 5(4):505-515.
24. Hu R, et al. (2012) PEGylated phospholipid micelle-encapsulated near-infrared PbS quantum dots for in vitro and in vivo bioimaging. Theranostics 2(7):723-733.
25. Cao J, et al. (2012) In vivo NIR imaging with PbS quantum dots entrapped in biodegradable micelles. J Biomed Mater Res A 100(4):958-968.
26. Choi HS, et al. (2007) Renal clearance of quantum dots. Nat Biotechnol 25(10): 1165-1170.
27. Antaris AL, et al. (2016) A small-molecule dye for NIR-II imaging. Nat Mater 15(2):235-242.
28. Balu M, et al. (2009) Effect of excitation wavelength on penetration depth in nonlinear optical microscopy of turbid media. J Biomed Opt 14(1):010508.
29. van Leeuwen-van Zaane F, et al. (2013) In vivo quantification of the scattering properties of tissue using multi-diameter single fiber reflectance spectroscopy. Biomed Opt Express 4(5):696-708.
30. Diao S, et al. (2015) Biological imaging without autofluorescence in the second nearinfrared region. Nano Res 8(9):3027-3034.
31. del Rosal B, Villa I, Jaque D, Sanz-Rodríguez F (2015) In vivo autofluorescence in the biological windows: The role of pigmentation. J Biophotonics, 10.1002/jbio.201500271.
32. McCreery RL (2005) Raman Spectroscopy for Chemical Analysis (Wiley, New York).
33. Welsher K, Sherlock SP, Dai H (2011) Deep-tissue anatomical imaging of mice using carbon nanotube fluorophores in the second near-infrared window. Proc Natl Acad Sci USA 108(22):8943-8948.
34. Su Y, et al. (2011) In vivo distribution, pharmacokinetics, and toxicity of aqueous synthesized cadmium-containing quantum dots. Biomaterials 32(25):5855-5862.
35. Valizadeh A, et al. (2012) Quantum dots: Synthesis, bioapplications, and toxicity. Nanoscale Res Lett 7(1):480.
36. Tsoi KM, Dai Q, Alman BA, Chan WC (2013) Are quantum dots toxic? Exploring the discrepancy between cell culture and animal studies. Acc Chem Res 46(3):662-671.
37. Domcke S, Sinha R, Levine DA, Sander C, Schultz N (2013) Evaluating cell lines as tumour models by comparison of genomic profiles. Nat Commun 4:2126.
38. Wang M, et al. (2009) Immunolabeling and NIR-excited fluorescent imaging of HeLa cells by using NaYF(4):Yb,Er upconversion nanoparticles. ACS Nano 3(6):1580-1586.
39. Ye X, et al. (2010) Morphologically controlled synthesis of colloidal upconversion nanophosphors and their shape-directed self-assembly. Proc Natl Acad Sci USA 107(52):22430-22435.
40. Somers RC, Snee PT, Bawendi MG, Nocera DG (2012) Energy transfer of CdSe/ZnS nanocrystals encapsulated with rhodamine-dye functionalized poly(acrylic acid). J Photochem Photobiol Chem 248:24-29.
41. Liu Z, et al. (2007) In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice. Nat Nanotechnol 2(1):47-52.
42. Hong G, et al. (2014) Ultrafast fluorescence imaging in vivo with conjugated polymer fluorophores in the second near-infrared window. Nat Commun 5:4206.
43. Welsher K, et al. (2009) A route to brightly fluorescent carbon nanotubes for nearinfrared imaging in mice. Nat Nanotechnol 4(11):773-780.