-
1
-
-
84975089176
-
Expression and manufacture of pharmaceutical proteins in genetically engineered horticultural plants
-
Mou B, Scorza R (eds), 1st edn. CRC, Boca Raton
-
Chen Q (2011) Expression and manufacture of pharmaceutical proteins in genetically engineered horticultural plants. In: Mou B, Scorza R (eds) Transgenic horticultural crops: challenges and opportunities, vol. 1, 1st edn. CRC, Boca Raton, pp 83–113
-
(2011)
Transgenic Horticultural Crops: Challenges and Opportunities
, vol.1
, pp. 83-113
-
-
Chen, Q.1
-
2
-
-
77249152189
-
Expression and purification of pharmaceutical proteins in plants
-
Chen Q (2008) Expression and purification of pharmaceutical proteins in plants. Biol Eng 1:291–321
-
(2008)
Biol Eng
, vol.1
, pp. 291-321
-
-
Chen, Q.1
-
3
-
-
79960377157
-
Turning a new leaf
-
Chen Q (2011) Turning a new leaf. Eur Biopharm Rev 2:64–68
-
(2011)
Eur Biopharm Rev
, vol.2
, pp. 64-68
-
-
Chen, Q.1
-
4
-
-
84856962688
-
Bioprocessing of plant-derived virus-like particles of Norwalk virus capsid protein under current Good Manufacture Practice regulations
-
Lai H, Chen Q (2012) Bioprocessing of plant-derived virus-like particles of Norwalk virus capsid protein under current Good Manufacture Practice regulations. Plant Cell Rep 31:573–584
-
(2012)
Plant Cell Rep
, vol.31
, pp. 573-584
-
-
Lai, H.1
Chen, Q.2
-
5
-
-
84902176028
-
Manufacturing economics of plant-made biologics: Case studies in therapeutic and industrial enzymes
-
Tuse D, Tu T, McDonald K (2014) Manufacturing economics of plant-made biologics: case studies in therapeutic and industrial enzymes. BioMed Res Int 2014:10
-
(2014)
Biomed Res Int
, vol.2014
, pp. 10
-
-
Tuse, D.1
Tu, T.2
McDonald, K.3
-
7
-
-
77954018329
-
Success stories in molecular farming—a brief overview
-
Faye L, Gomord V (2010) Success stories in molecular farming—a brief overview. Plant Biotechnol J 8:525–528
-
(2010)
Plant Biotechnol J
, vol.8
, pp. 525-528
-
-
Faye, L.1
Gomord, V.2
-
8
-
-
77951533858
-
Subunit vaccines produced using plant biotechnology
-
Levine MM, Informa Healthcare, USA
-
Chen Q, Mason HS, Mor T et al (2009) Subunit vaccines produced using plant biotechnology. In: Levine MM (ed) New generation vaccines. Informa Healthcare, USA, pp 306–14
-
(2009)
New Generation Vaccines
, pp. 306-314
-
-
Chen, Q.1
Mason, H.S.2
Mor, T.3
-
9
-
-
77956440770
-
Commercialization of whole-plant systems for biomanufacturing of protein products: Evolution and prospects
-
Davies HM (2010) Commercialization of whole-plant systems for biomanufacturing of protein products: evolution and prospects. Plant Biotechnol J 8:845–861
-
(2010)
Plant Biotechnol J
, vol.8
, pp. 845-861
-
-
Davies, H.M.1
-
10
-
-
26944486269
-
Stable plastid transformation in lettuce (Lactuca sativa L.)
-
Lelivelt CC, McCabe M, Newell C et al (2005) Stable plastid transformation in lettuce (Lactuca sativa L.). Plant Mol Biol 58:763–774
-
(2005)
Plant Mol Biol
, vol.58
, pp. 763-774
-
-
Lelivelt, C.C.1
McCabe, M.2
Newell, C.3
-
11
-
-
77955260676
-
Transient expression systems for plant-derived biopharmaceuticals
-
Komarova TV, Baschieri S, Donini M et al (2010) Transient expression systems for plant-derived biopharmaceuticals. Expert Rev Vaccines 9:859–876
-
(2010)
Expert Rev Vaccines
, vol.9
, pp. 859-876
-
-
Komarova, T.V.1
Baschieri, S.2
Donini, M.3
-
12
-
-
84880841565
-
Efficient agroinfiltration of plants for high-level transient expression of recombinant proteins
-
Leuzinger K, Dent M, Hurtado J et al (2013) Efficient agroinfiltration of plants for high-level transient expression of recombinant proteins. J Vis Exp. doi:10.3791/50521
-
(2013)
J Vis Exp
-
-
Leuzinger, K.1
Dent, M.2
Hurtado, J.3
-
13
-
-
84880768342
-
Agroinfiltration as an effective and scalable strategy of gene delivery for production of pharmaceutical proteins
-
Chen Q, Lai H, Hurtado J et al (2013) Agroinfiltration as an effective and scalable strategy of gene delivery for production of pharmaceutical proteins. Adv Tech Biol Med 1:2
-
(2013)
Adv Tech Biol Med
, vol.1
, pp. 2
-
-
Chen, Q.1
Lai, H.2
Hurtado, J.3
-
14
-
-
25144467500
-
High-level transient expression of recombinant protein in lettuce
-
Joh LD, Wroblewski T, Ewing NN et al (2005) High-level transient expression of recombinant protein in lettuce. Biotechnol Bioeng 91:861–871
-
(2005)
Biotechnol Bioeng
, vol.91
, pp. 861-871
-
-
Joh, L.D.1
Wroblewski, T.2
Ewing, N.N.3
-
15
-
-
46049083590
-
Viral vectors for production of recombinant proteins in plants
-
Lico C, Chen Q, Santi L (2008) Viral vectors for production of recombinant proteins in plants. J Cell Physiol 216:366–377
-
(2008)
J Cell Physiol
, vol.216
, pp. 366-377
-
-
Lico, C.1
Chen, Q.2
Santi, L.3
-
16
-
-
1542291115
-
Engineering viral expression vectors for plants: The ‘full virus’ and the ‘deconstructed virus’ strategies
-
Gleba Y, Marillonnet S, Klimyuk V (2004) Engineering viral expression vectors for plants: the ‘full virus’ and the ‘deconstructed virus’ strategies. Curr Opin Plant Biol 7:182–188
-
(2004)
Curr Opin Plant Biol
, vol.7
, pp. 182-188
-
-
Gleba, Y.1
Marillonnet, S.2
Klimyuk, V.3
-
17
-
-
40849140609
-
An efficient plant viral expression system generating orally immunogenic Norwalk virus-like particles
-
Santi L, Batchelor L, Huang Z et al (2008) An efficient plant viral expression system generating orally immunogenic Norwalk virus-like particles. Vaccine 26:1846–1854
-
(2008)
Vaccine
, vol.26
, pp. 1846-1854
-
-
Santi, L.1
Batchelor, L.2
Huang, Z.3
-
18
-
-
23644457158
-
Expression of porcine prorelaxin in transgenic tobacco
-
Buswell S, Medina-Bolivar F, Chen Q et al (2005) Expression of porcine prorelaxin in transgenic tobacco. Ann N Y Acad Sci 1041: 77–81
-
(2005)
Ann N Y Acad Sci
, vol.1041
, pp. 77-81
-
-
Buswell, S.1
Medina-Bolivar, F.2
Chen, Q.3
-
19
-
-
24944498904
-
Systemic Agrobacterium tumefaciens-mediated transfection of viral replicons for efficient transient expression in plants
-
Marillonnet S, Thoeringer C, Kandzia R et al (2005) Systemic Agrobacterium tumefaciens-mediated transfection of viral replicons for efficient transient expression in plants. Nat Biotechnol 23:718–723
-
(2005)
Nat Biotechnol
, vol.23
, pp. 718-723
-
-
Marillonnet, S.1
Thoeringer, C.2
Kandzia, R.3
-
20
-
-
79953675401
-
Geminiviral vectors based on bean yellow dwarf virus for production of vaccine antigens and monoclonal antibodies in plants
-
Chen Q, He J, Phoolcharoen W et al (2011) Geminiviral vectors based on bean yellow dwarf virus for production of vaccine antigens and monoclonal antibodies in plants. Hum Vaccin 7:331–338
-
(2011)
Hum Vaccin
, vol.7
, pp. 331-338
-
-
Chen, Q.1
He, J.2
Phoolcharoen, W.3
-
21
-
-
77949479819
-
High-level rapid production of full-size monoclonal antibodies in plants by a single-vector DNA replicon system
-
Huang Z, Phoolcharoen W, Lai H et al (2010) High-level rapid production of full-size monoclonal antibodies in plants by a single-vector DNA replicon system. Biotechnol Bioeng 106: 9–17
-
(2010)
Biotechnol Bioeng
, vol.106
, pp. 9-17
-
-
Huang, Z.1
Phoolcharoen, W.2
Lai, H.3
-
22
-
-
67650156117
-
A DNA replicon system for rapid high-level production of virus-like particles in plants
-
Huang Z, Chen Q, Hjelm B et al (2009) A DNA replicon system for rapid high-level production of virus-like particles in plants. Biotechnol Bioeng 103:706–714
-
(2009)
Biotechnol Bioeng
, vol.103
, pp. 706-714
-
-
Huang, Z.1
Chen, Q.2
Hjelm, B.3
-
23
-
-
83055181327
-
Robust production of virus-like particles and monoclonal antibodies with geminiviral replicon vectors in lettuce
-
Lai H, He J, Engle M et al (2012) Robust production of virus-like particles and monoclonal antibodies with geminiviral replicon vectors in lettuce. Plant Biotechnol J 10:95–104
-
(2012)
Plant Biotechnol J
, vol.10
, pp. 95-104
-
-
Lai, H.1
He, J.2
Engle, M.3
-
24
-
-
20744443090
-
Optimization of Agrobacterium-mediated transient assays of gene expression in lettuce, tomato and Arabidopsis
-
Wroblewski T, Tomczak A, Michelmore R (2005) Optimization of Agrobacterium-mediated transient assays of gene expression in lettuce, tomato and Arabidopsis. Plant Biotechnol J 3:259–273
-
(2005)
Plant Biotechnol J
, vol.3
, pp. 259-273
-
-
Wroblewski, T.1
Tomczak, A.2
Michelmore, R.3
-
25
-
-
84855543357
-
A novel system for rapid and cost-effective production of detection and diagnostic reagents of West Nile Virus in plants
-
He J, Lai H, Brock C et al (2012) A novel system for rapid and cost-effective production of detection and diagnostic reagents of West Nile Virus in plants. J Biomed Biotechnol 2012:10
-
(2012)
J Biomed Biotechnol
, vol.2012
, pp. 10
-
-
He, J.1
Lai, H.2
Brock, C.3
-
26
-
-
84890546904
-
Transient expression of human growth hormone in potato (Solanum tuberosum), tobacco (Nicotiana tobacum) and lettuce (Lactuca sativa) leaves by agroinfiltration Iranian
-
Sohi HH, Jourabchi E, Khodabandeh M (2005) Transient expression of human growth hormone in potato (Solanum tuberosum), tobacco (Nicotiana tobacum) and lettuce (Lactuca sativa) leaves by agroinfiltration Iranian. J Biotechnol 3:109–113
-
(2005)
J Biotechnol
, vol.3
, pp. 109-113
-
-
Sohi, H.H.1
Jourabchi, E.2
Khodabandeh, M.3
-
27
-
-
21444444551
-
Highly efficient transient expression of functional recombinant antibodies in lettuce
-
Negrouk V, Eisner G, Lee H-I et al (2005) Highly efficient transient expression of functional recombinant antibodies in lettuce. Plant Sci 169:433–438
-
(2005)
Plant Sci
, vol.169
, pp. 433-438
-
-
Negrouk, V.1
Eisner, G.2
Lee, H.-I.3
-
28
-
-
0032863164
-
A plant-derived edible vaccine against hepatitis B virus
-
Kapusta J, Modelska A, Figlerowicz M et al (1999) A plant-derived edible vaccine against hepatitis B virus. FASEB J 13:1796–1799
-
(1999)
FASEB J
, vol.13
, pp. 1796-1799
-
-
Kapusta, J.1
Modelska, A.2
Figlerowicz, M.3
-
29
-
-
77953686970
-
Expression of an immunogenic F1-V fusion protein in lettuce as a plant-based vaccine against plague
-
Rosales-Mendoza S, Soria-Guerra R, Moreno-Fierros L et al (2010) Expression of an immunogenic F1-V fusion protein in lettuce as a plant-based vaccine against plague. Planta 232:409–416
-
(2010)
Planta
, vol.232
, pp. 409-416
-
-
Rosales-Mendoza, S.1
Soria-Guerra, R.2
Moreno-Fierros, L.3
-
30
-
-
33645214025
-
Measles virus hemagglutinin protein expressed in transgenic lettuce induces neutralising antibodies in mice following mucosal vaccination
-
Webster DE, Smith SD, Pickering RJ et al (2006) Measles virus hemagglutinin protein expressed in transgenic lettuce induces neutralising antibodies in mice following mucosal vaccination. Vaccine 24:3538–3544
-
(2006)
Vaccine
, vol.24
, pp. 3538-3544
-
-
Webster, D.E.1
Smith, S.D.2
Pickering, R.J.3
-
31
-
-
79955917510
-
Low-dose oral immunization with lyophilized tissue of herbicide-resistant lettuce expressing hepatitis B surface antigen for prototype plant-derived vaccine tablet formulation
-
Pniewski T, Kapusta J, Bociąg P et al (2011) Low-dose oral immunization with lyophilized tissue of herbicide-resistant lettuce expressing hepatitis B surface antigen for prototype plant-derived vaccine tablet formulation. J Appl Genet 52:125–136
-
(2011)
J Appl Genet
, vol.52
, pp. 125-136
-
-
Pniewski, T.1
Kapusta, J.2
Bociąg, P.3
-
32
-
-
33947502240
-
Transient expression of an active human interferon-beta in lettuce
-
Li J, Chen M, Liu X-W et al (2007) Transient expression of an active human interferon-beta in lettuce. Sci Hortic 112:258–265
-
(2007)
Sci Hortic
, vol.112
, pp. 258-265
-
-
Li, J.1
Chen, M.2
Liu, X.-W.3
-
33
-
-
47749105359
-
Transient expression of chicken alpha interferon gene in lettuce
-
Li S, De-gang Z, Yong-jun W et al (2008) Transient expression of chicken alpha interferon gene in lettuce. J Zhejiang Univ Sci B 9:351–355
-
(2008)
J Zhejiang Univ Sci B
, vol.9
, pp. 351-355
-
-
Li, S.1
De-Gang, Z.2
Yong-Jun, W.3
-
34
-
-
84899561933
-
Virus-like particle vaccines for norovirus gastroenteritis
-
Giese M (ed), Springer, Vienna
-
Chen Q (2013) Virus-like particle vaccines for norovirus gastroenteritis. In: Giese M (ed) Molecular vaccines, vol 1. Springer, Vienna, pp 153–81. doi:10.1007/978-3-7091-1419-3_8
-
(2013)
Molecular Vaccines
, vol.1
, pp. 153-181
-
-
Chen, Q.1
-
35
-
-
84874755493
-
Plant-derived virus-like particles as vaccines
-
Chen Q, Lai H (2013) Plant-derived virus-like particles as vaccines. Hum Vacc Immunother 9:26–49
-
(2013)
Hum Vacc Immunother
, vol.9
, pp. 26-49
-
-
Chen, Q.1
Lai, H.2
-
36
-
-
77249090742
-
Monoclonal antibody produced in plants efficiently treats West Nile virus infection in mice
-
Lai H, Engle M, Fuchs A et al (2010) Monoclonal antibody produced in plants efficiently treats West Nile virus infection in mice. Proc Natl Acad Sci U S A 107:2419–2424
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 2419-2424
-
-
Lai, H.1
Engle, M.2
Fuchs, A.3
-
37
-
-
84899504050
-
A Plant-Produced Antigen Elicits Potent Immune Responses against West Nile Virus in Mice
-
He J, Peng L, Lai H et al (2014) A Plant-Produced Antigen Elicits Potent Immune Responses against West Nile Virus in Mice. BioMed Res Int 2014:10
-
(2014)
Biomed Res Int
, vol.2014
, pp. 10
-
-
He, J.1
Peng, L.2
Lai, H.3
-
38
-
-
79961171492
-
Expression of an immunogenic Ebola immune complex in Nicotiana benthamiana
-
Phoolcharoen W, Bhoo SH, Lai H et al (2011) Expression of an immunogenic Ebola immune complex in Nicotiana benthamiana. Plant Biotechnol J 9:807–816
-
(2011)
Plant Biotechnol J
, vol.9
, pp. 807-816
-
-
Phoolcharoen, W.1
Bhoo, S.H.2
Lai, H.3
-
39
-
-
84899542375
-
Generation and analysis of novel plant-derived antibody-based therapeutic molecules against West Nile Virus
-
He J, Lai H, Engle M et al (2014) Generation and analysis of novel plant-derived antibody-based therapeutic molecules against West Nile Virus. PLoS One 9:e93541. doi:10.1371/journal.pone.0093541
-
(2014)
Plos One
, vol.9
-
-
He, J.1
Lai, H.2
Engle, M.3
-
40
-
-
84925932871
-
Structural and functional characterization of an anti-West Nile virus monoclonal antibody and its single-chain variant produced in glycoengineered plants
-
Lai H, He J, Hurtado J et al (2014) Structural and functional characterization of an anti-West Nile virus monoclonal antibody and its single-chain variant produced in glycoengineered plants. Plant Biotechnol J 12(8):1098–1107
-
(2014)
Plant Biotechnol J
, vol.12
, Issue.8
, pp. 1098-1107
-
-
Lai, H.1
He, J.2
Hurtado, J.3
-
41
-
-
84855483647
-
A nonreplicating subunit vaccine protects mice against lethal Ebola virus challenge
-
Phoolcharoen W, Dye JM, Kilbourne J et al (2011) A nonreplicating subunit vaccine protects mice against lethal Ebola virus challenge. Proc Natl Acad Sci U S A 108:20695–20700
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 20695-20700
-
-
Phoolcharoen, W.1
Dye, J.M.2
Kilbourne, J.3
|