Expression of an immunogenic F1-V fusion protein in lettuce as a plant-based vaccine against plague

Planta

Volumn 232, Issue 2, 2010, Pages 409-416

  Rosales Mendoza, Sergio ^a   Soria Guerra, Ruth E ^b   Moreno Fierros, Leticia ^c   Alpuche Solís, Ángel G ^d   Martínez González, Luzmila ^d   Korban, Schuyler S ^b  

^a UNIVERSIDAD AUTÓNOMA DE SAN LUIS POTOSÍ   (Mexico)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^d INSTITUTO POTOSINO DE INVESTIGACIÓN CIENTÍFICA Y TECNOLÓGICA   (Mexico)

Author keywords

Antigenic fusion protein; Plague; Plant based vaccine; Transgenic plants; Yersinia pestis

Indexed keywords

BACTERIAL ANTIGEN; HYBRID PROTEIN; LCRV PROTEIN, YERSINIA; PLAGUE VACCINE; PORE FORMING CYTOTOXIC PROTEIN;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; IMMUNOLOGY; LETTUCE; METABOLISM; MICROBIOLOGY; MOUSE; PATHOGENICITY; PLAGUE; POLYMERASE CHAIN REACTION; RHIZOBIUM; TRANSGENIC PLANT; WESTERN BLOTTING; YERSINIA PESTIS;

ANIMALS; ANTIGENS, BACTERIAL; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; LETTUCE; MICE; MICE, INBRED BALB C; PLAGUE; PLAGUE VACCINE; PLANTS, GENETICALLY MODIFIED; POLYMERASE CHAIN REACTION; PORE FORMING CYTOTOXIC PROTEINS; RECOMBINANT FUSION PROTEINS; RHIZOBIUM; YERSINIA PESTIS;

AGROBACTERIUM; LACTUCA; MUS; RHIZOBIUM; YERSINIA PESTIS;

EID: 77953686970     PISSN: 00320935     EISSN: 14322048     Source Type: Journal    
DOI: 10.1007/s00425-010-1176-z     Document Type: Article

References (26)

1. Alvarez ML, Pinyerd HL, Crisantes JD, Rigano MM, Pinkhasov J, Walmsley AM, Mason HS, Cardineau GA (2006) Plant-made subunit vaccine against pneumonic and bubonic plague is orally immunogenic in mice. Vaccine 24: 2477-2490.
2. Alvarez ML, Topal E, Martin F, Cardineau GA (2010) Higher accumulation of F1-V fusion recombinant protein in plants after induction of protein body formation. Plant Mol Biol 72: 75-89.
3. Arlen PA, Singleton M, Adamovicz JJ, Ding Y, Davoodi-Semiromi A, Daniell H (2008) Effective plague vaccination via oral delivery of plant cells expressing F1-V antigens in chloroplasts. Infect Immun 76: 3640-3650.
4. Arntzen C, Plotkin S, Dodet B (2005) Plant-derived vaccines and antibodies: potential and limitations. Vaccine 23: 1753-1756.
5. Bradford MM (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.
6. Centers for Disease Control and Prevention (2005) Plague information: CDC division of vector-borne infectious diseases. http://www.cdc.gov/ncidod/dvbid/plague/index.htm.
7. Cornelius CL, Anderson QD, Schneewind O (2007) Protective immunity against plague. Adv Exp Med Biol 603: 415-424.
8. Curtis IS (2006) Lettuce (Lactuca sativa L.). Methods Mol Biol 343: 449-458.
9. Dellaporta SL, Wood J, Hicks JB (1983) A plant DNA minipreparation: version I. Plant Mol Biol Rep 1: 19-21.
10. Gamborg OL, Miller RA, Ojima K (1968) Nutrient requirements of suspension cultures of soybean root cells. Exp Cell Res 50: 151-158.
11. Gelvin SB (1998) The introduction and expression of transgenes in plants. Curr Opin Biotechnol 9: 227-232.
12. Haq TA, Mason HS, Clements JD, Arntzen CJ (1995) Oral Immunization with a recombinant bacterial antigen produced in transgenic plants. Science 268: 714-716.
13. Horn ME, Woodard SL, Howard JA (2004) Plant molecular farming: systems and products. Plant Cell Rep 22: 711-720.
14. Kanamoto H, Yamashita A, Asao H, Okumura S, Takase H, Hattori M, Yokota A, Tomizawa K (2006) Efficient and stable transformation of Lactuca sativa L cv. Cisco (lettuce) plastids. Transgenic Res 15: 205-217.
15. Kapusta J, Modelska A, Figlerowicz M, Pniewski T, Letellier M, Lisowa O, Yusibov V, Koprowski H, Plucienniczak A, Legocki AB (1999) A plant-derived edible vaccine against hepatitis B virus. FASEB J 13: 1796-1799.
16. Lelivelt CL, McCabe MS, Newell CA, Desnoo CB, van Dun KM, Birch-Machin I, Gray JC, Mills KH, Nugent JM (2005) Stable plastid transformation in lettuce (Lactuca sativa L.). Plant Mol Biol 58: 763-774.
17. Li HY, Ramalingam S, Chye ML (2006) Accumulation of recombinant SARS-CoV spike protein in plant cytosol and chloroplasts indicate potential for development of plant-derived oral vaccines. Exp Biol Med 231: 1346-1352.
18. Marcondes J, Hansen E (2008) Transgenic lettuce seedlings carrying hepatitis B virus antigen HBsAg. Braz J Infect Dis 12: 469-471.
19. Meyer KF, Cavanaugh DC, Bartelloni PJ, Marshall JD (1974) Plague immunization: past and present trends. J Infect Dis 129 (suppl): S13-S18.
20. Murashige T, Skoog F (1962) A revised medium for rapid growth and bioassays with tobacco tissue culture. Physiol Plant 15: 473-479.
21. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
22. Santi L, Giritch A, Roy CJ, Marillonnet S, Klimyuk V, Gleba Y, Webb R, Arntzen CJ, Mason HS (2006) Protection conferred by recombinant Yersinia pestis antigens produced by a rapid and highly scalable plant expression system. Proc Natl Acad Sci USA 103: 861-866.
23. Smiley ST (2008) Current challenges in the development of vaccines for pneumonic plague. Exp Rev Vaccines 7: 209-221.
24. Tacket CO, Mason HS, Losonsky G, Clements JD, Wasserman SS, Levine MM, Arntzen CJ (1998) Immunogenicity in humans of a recombinant bacterial-antigen delivered in transgenic potato. Nat Med 4: 607-609.
25. Williamson ED, Eley SM, Stagg AJ, Green M, Russell P, Titball RW (2000) A single dose subunit vaccine protects against pneumonic plague. Vaccine 19: 566-571.
26. Williamson ED, Flick-Smith HC, Lebutt C, Rowland CA, Jones SM, Waters EL, Gwyther RJ, Miller J, Packer PJ, Irving M (2005) Human immune response to a plague vaccine comprising recombinant F1 and V antigens. Infect Immun 73: 3598-3608.