Genome-wide microRNA changes in human intracranial aneurysms

BMC Neurology

Volumn 14, Issue 1, 2014, Pages

  Liu, Dehua ^a   Han, Liang ^a   Wu, Xiao ^b   Yang, Xinjian ^c   Zhang, Qunye ^b   Jiang, Fan ^b  

^a JILIN UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Cerebral vascular disease; Human; Intracranial aneurysm; Microarray; MicroRNA; Protein translation machinery; System biology; Transcriptome

Indexed keywords

MICRORNA; MICRORNA 1; MICRORNA 101; MICRORNA 10A; MICRORNA 124A; MICRORNA 125A 5P; MICRORNA 125B; MICRORNA 126; MICRORNA 133A; MICRORNA 139; MICRORNA 143; MICRORNA 145; MICRORNA 146A; MICRORNA 155; MICRORNA 17; MICRORNA 199B 5P; MICRORNA 218; MICRORNA 222; MICRORNA 223; MICRORNA 23B; MICRORNA 24 1; MICRORNA 26A; MICRORNA 296 5P; MICRORNA 30C; MICRORNA 30E; MICRORNA 330 3P; MICRORNA 338 3P; MICRORNA 362 5P; MICRORNA LET 7; UNCLASSIFIED DRUG; TRANSCRIPTOME;

ADULT; AGED; APOPTOSIS; ARTICLE; BIOINFORMATICS; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION; HUMAN; HUMAN GENOME; HUMAN TISSUE; HYPERTENSION; INTRACRANIAL ANEURYSM; MACROPHAGE; MALE; MEDICAL HISTORY; MICROARRAY ANALYSIS; MONOCYTE; OXIDATIVE STRESS; PATHOGENESIS; PHENOTYPE; RNA ANALYSIS; SUPERFICIAL TEMPORAL ARTERY; UPREGULATION; VASCULAR SMOOTH MUSCLE CELL; GENETIC ASSOCIATION; METABOLISM; MIDDLE AGED;

FEMALE; GENE EXPRESSION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INTRACRANIAL ANEURYSM; MALE; MICROARRAY ANALYSIS; MICRORNAS; MIDDLE AGED; TRANSCRIPTOME;

EID: 84965090918     PISSN: None     EISSN: 14712377     Source Type: Journal    
DOI: 10.1186/s12883-014-0188-x     Document Type: Article

References (63)

1. Krings T, Mandell DM, Kiehl TR, Geibprasert S, Tymianski M, Alvarez H, ter Brugge KG, Hans FJ: Intracranial aneurysms: from vessel wall pathology to therapeutic approach. Nat Rev Neurol 2011, 7(10):547-559.
2. Brown RD: Unruptured intracranial aneurysms. Semin Neurol 2010, 30(5):537-544.
3. Steiner T, Juvela S, Unterberg A, Jung C, Forsting M, Rinkel G: European Stroke Organization guidelines for the management of intracranial aneurysms and subarachnoid haemorrhage. Cerebrovasc Dis 2013, 35(2):93-112.
4. Wardlaw JM, White PM: The detection and management of unruptured intracranial aneurysms. Brain 2000, 123(Pt 2):205-221.
5. Clarke M: Systematic review of reviews of risk factors for intracranial aneurysms. Neuroradiology 2008, 50(8):653-664.
6. Juvela S, Poussa K, Porras M: Factors affecting formation and growth of intracranial aneurysms: a long-term follow-up study. Stroke 2001, 32(2):485-491.
7. Chalouhi N, Ali MS, Jabbour PM, Tjoumakaris SI, Gonzalez LF, Rosenwasser RH, Koch WJ, Dumont AS: Biology of intracranial aneurysms: role of inflammation. J Cereb Blood Flow Metab 2012, 32(9):1659-1676.
8. Sforza DM, Putman CM, Cebral JR: Hemodynamics of Cerebral Aneurysms. Annu Rev Fluid Mech 2009, 41:91-107.
9. Omodaka S, Sugiyama S, Inoue T, Funamoto K, Fujimura M, Shimizu H, Hayase T, Takahashi A, Tominaga T: Local hemodynamics at the rupture point of cerebral aneurysms determined by computational fluid dynamics analysis. Cerebrovasc Dis 2012, 34(2):121-129.
10. Shiue I, Arima H, Hankey GJ, Anderson CS: Dietary intake of key nutrients and subarachnoid hemorrhage: a population-based case-control study in Australasia. Cerebrovasc Dis 2011, 31(5):464-470.
11. Ruigrok YM, Rinkel GJ, Wijmenga C: Genetics of intracranial aneurysms. Lancet Neurol 2005, 4(3):179-189.
12. Caranci F, Briganti F, Cirillo L, Leonardi M, Muto M: Epidemiology and genetics of intracranial aneurysms. Eur J Radiol 2013, 82(10):1598-1605.
13. Pera J, Korostynski M, Krzyszkowski T, Czopek J, Slowik A, Dziedzic T, Piechota M, Stachura K, Moskala M, Przewlocki R, Szczudlik A: Gene expression profiles in human ruptured and unruptured intracranial aneurysms: what is the role of inflammation? Stroke 2010, 41(2):224-231.
14. Krischek B, Kasuya H, Tajima A, Akagawa H, Sasaki T, Yoneyama T, Ujiie H, Kubo O, Bonin M, Takakura K, Hori T, Inoue I: Network-based gene expression analysis of intracranial aneurysm tissue reveals role of antigen presenting cells. Neuroscience 2008, 154(4):1398-1407.
15. Li L, Yang X, Jiang F, Dusting GJ, Wu Z: Transcriptome-wide characterization of gene expression associated with unruptured intracranial aneurysms. Eur Neurol 2009, 62(6):330-337.
16. Shi C, Awad IA, Jafari N, Lin S, Du P, Hage ZA, Shenkar R, Getch CC, Bredel M, Batjer HH, Bendok BR: Genomics of human intracranial aneurysm wall. Stroke 2009, 40(4):1252-1261.
17. Marchese E, Vignati A, Albanese A, Nucci CG, Sabatino G, Tirpakova B, Lofrese G, Zelano G, Maira G: Comparative evaluation of genome-wide gene expression profiles in ruptured and unruptured human intracranial aneurysms. J Biol Regul Homeost Agents 2010, 24(2):185-195.
18. Roder C, Kasuya H, Harati A, Tatagiba M, Inoue I, Krischek B: Meta-analysis of microarray gene expression studies on intracranial aneurysms. Neuroscience 2012, 201:105-113.
19. Bartel DP: MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116(2):281-297.
20. He L, Hannon GJ: MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 2004, 5(7):522-531.
21. Bonauer A, Boon RA, Dimmeler S: Vascular microRNAs. Curr Drug Targets 2010, 11(8):943-949.
22. McDonald RA, Hata A, MacLean MR, Morrell NW, Baker AH: MicroRNA and vascular remodelling in acute vascular injury and pulmonary vascular remodelling. Cardiovasc Res 2012, 93(4):594-604.
23. Wei Y, Schober A, Weber C: Pathogenic arterial remodeling: the good and bad of microRNAs. Am J Physiol Heart Circ Physiol 2013, 304(8):H1050-H1059.
24. Pahl MC, Derr K, Gäbel G, Hinterseher I, Elmore JR, Schworer CM, Peeler TC, Franklin DP, Gray JL, Carey DJ, Tromp G, Kuivaniemi H: MicroRNA expression signature in human abdominal aortic aneurysms. BMC Med Genomics 2012, 5:25.
25. Kin K, Miyagawa S, Fukushima S, Shirakawa Y, Torikai K, Shimamura K, Daimon T, Kawahara Y, Kuratani T, Sawa Y: Tissue-and plasma-specific MicroRNA signatures for atherosclerotic abdominal aortic aneurysm. J Am Heart Assoc 2012, 1(5):e000745.
26. Jiang Y, Zhang M, He H, Chen J, Zeng H, Li J, Duan R: MicroRNA/mRNA profiling and regulatory network of intracranial aneurysm. BMC Med Genomics 2013, 6(1):36.
27. Guo D, Liu J, Wang W, Hao F, Sun X, Wu X, Bu P, Zhang Y, Liu Y, Liu F, Zhang Q, Jiang F: Alteration in Abundance and Compartmentalization of Inflammation-Related miRNAs in Plasma After Intracerebral Hemorrhage. Stroke 2013, 44(6):1739-1742.
28. Xiao F, Zuo Z, Cai G, Kang S, Gao X, Li T: miRecords: an integrated resource for microRNA-target interactions. Nucleic Acids Res 2009, 37(Database issue):D105-D110.
29. Vergoulis T, Vlachos IS, Alexiou P, Georgakilas G, Maragkakis M, Reczko M, Gerangelos S, Koziris N, Dalamagas T, Hatzigeorgiou AG: TarBase 6.0: capturing the exponential growth of miRNA targets with experimental support. Nucleic Acids Res 2012, 40(Database issue):D222-D229.
30. da Huang W, Sherman BT, Lempicki RA: Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009, 4(1):44-57.
31. Kohl M, Wiese S, Warscheid B: Cytoscape: software for visualization and analysis of biological networks. Methods Mol Biol 2011, 696:291-303.
32. Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25(4):402-408.
33. Santoro MM, Nicoli S: miRNAs in endothelial cell signaling: the endomiRNAs. Exp Cell Res 2013, 319(9):1324-1330.
34. Robinson HC, Baker AH: How do microRNAs affect vascular smooth muscle cell biology? Curr Opin Lipidol 2012, 23(5):405-411.
35. Xie C, Zhang J, Chen YE: MicroRNA and vascular smooth muscle cells. Vitam Horm 2011, 87:321-339.
36. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F: Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002, 3(7):RESEARCH0034.
37. Penn DL, Witte SR, Komotar RJ, Sander Connolly E Jr: The role of vascular remodeling and inflammation in the pathogenesis of intracranial aneurysms. J Clin Neurosci 2014, 21(1):28-32.
38. Bruno G, Todor R, Lewis I, Chyatte D: Vascular extracellular matrix remodeling in cerebral aneurysms. J Neurosurg 1998, 89(3):431-440.
39. Starke RM, Chalouhi N, Ali MS, Jabbour PM, Tjoumakaris SI, Gonzalez LF, Rosenwasser RH, Koch WJ, Dumont AS: The role of oxidative stress in cerebral aneurysm formation and rupture. Curr Neurovasc Res 2013, 10(3):247-255.
40. Frosen J, Tulamo R, Paetau A, Laaksamo E, Korja M, Laakso A, Niemela M, Hernesniemi J: Saccular intracranial aneurysm: pathology and mechanisms. Acta Neuropathol 2012, 123(6):773-786.
41. Fang JH, Zhou HC, Zeng C, Yang J, Liu Y, Huang X, Zhang JP, Guan XY, Zhuang SM: MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression. Hepatology 2011, 54(5):1729-1740.
42. Aoki T, Kataoka H, Morimoto M, Nozaki K, Hashimoto N: Macrophagederived matrix metalloproteinase-2 and-9 promote the progression of cerebral aneurysms in rats. Stroke 2007, 38(1):162-169.
43. Maegdefessel L, Azuma J, Toh R, Merk DR, Deng A, Chin JT, Raaz U, Schoelmerich AM, Raiesdana A, Leeper NJ, McConnell MV, Dalman RL, Spin JM, Tsao PS: Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development. J Clin Invest 2012, 122(2):497-506.
44. Nohata N, Hanazawa T, Enokida H, Seki N: microRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers. Oncotarget 2012, 3(1):9-21.
45. Liu N, Bezprozvannaya S, Williams AH, Qi X, Richardson JA, Bassel-Duby R, Olson EN: microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev 2008, 22(23):3242-3254.
46. Liu N, Bezprozvannaya S, Shelton JM, Frisard MI, Hulver MW, McMillan RP, Wu Y, Voelker KA, Grange RW, Richardson JA, Bassel-Duby R, Olson EN: Mice lacking microRNA 133a develop dynamin 2-dependent centronuclear myopathy. J Clin Invest 2011, 121(8):3258-3268.
47. Guo X, Guo L, Ji J, Zhang J, Zhang J, Chen X, Cai Q, Li J, Gu Q, Liu B, Zhu Z, Yu Y: miRNA-331-3p directly targets E2F1 and induces growth arrest in human gastric cancer. Biochem Biophys Res Commun 2010, 398(1):1-6.
48. van't Hof FN, Ruigrok YM, Baas AF, Kiemeney LA, Vermeulen SH, Uitterlinden AG, Hofman A, Rivadeneira F, Rinkel GJ, de Bakker PI: Impact of inherited genetic variants associated with lipid profile, hypertension, and coronary artery disease on the risk of intracranial and abdominal aortic aneurysms. Circ Cardiovasc Genet 2013, 6(3):264-270.
49. Scheper GC, van der Knaap MS, Proud CG: Translation matters: protein synthesis defects in inherited disease. Nat Rev Genet 2007, 8(9):711-723.
50. Casad ME, Abraham D, Kim IM, Frangakis S, Dong B, Lin N, Wolf MJ, Rockman HA: Cardiomyopathy is associated with ribosomal protein gene haploinsufficiency in Drosophila melanogaster. Genetics 2011, 189(3):861-870.
51. Hannan RD, Stefanovsky V, Taylor L, Moss T, Rothblum LI: Overexpression of the transcription factor UBF1 is sufficient to increase ribosomal DNA transcription in neonatal cardiomyocytes: implications for cardiac hypertrophy. Proc Natl Acad Sci U S A 1996, 93(16):8750-8755.
52. Mourani PM, Garl PJ, Wenzlau JM, Carpenter TC, Stenmark KR, Weiser-Evans MC: Unique, highly proliferative growth phenotype expressed by embryonic and neointimal smooth muscle cells is driven by constitutive Akt, mTOR, and p70S6K signaling and is actively repressed by PTEN. Circulation 2004, 109(10):1299-1306.
53. Hegner B, Lange M, Kusch A, Essin K, Sezer O, Schulze-Lohoff E, Luft FC, Gollasch M, Dragun D: mTOR regulates vascular smooth muscle cell differentiation from human bone marrow-derived mesenchymal progenitors. Arterioscler Thromb Vasc Biol 2009, 29(2):232-238.
54. Ma XM, Blenis J: Molecular mechanisms of mTOR-mediated translational control. Nat Rev Mol Cell Biol 2009, 10(5):307-318.
55. Rodier F, Campisi J, Bhaumik D: Two faces of p53: aging and tumor suppression. Nucleic Acids Res 2007, 35(22):7475-7484.
56. Kim R: Unknotting the roles of Bcl-2 and Bcl-xL in cell death. Biochem Biophys Res Commun 2005, 333(2):336-343.
57. Hara A, Yoshimi N, Mori H: Evidence for apoptosis in human intracranial aneurysms. Neurol Res 1998, 20(2):127-130.
58. Takagi Y, Ishikawa M, Nozaki K, Yoshimura S, Hashimoto N: Increased expression of phosphorylated c-Jun amino-terminal kinase and phosphorylated c-Jun in human cerebral aneurysms: role of the c-Jun amino-terminal kinase/c-Jun pathway in apoptosis of vascular walls. Neurosurgery 2002, 51(4):997-1002. discussion 1002-1004.
59. Laaksamo E, Tulamo R, Baumann M, Dashti R, Hernesniemi J, Juvela S, Niemela M, Laakso A: Involvement of mitogen-activated protein kinase signaling in growth and rupture of human intracranial aneurysms. Stroke 2008, 39(3):886-892.
60. Weinsheimer S, Lenk GM, van der Voet M, Land S, Ronkainen A, Alafuzoff I, Kuivaniemi H, Tromp G: Integration of expression profiles and genetic mapping data to identify candidate genes in intracranial aneurysm. Physiol Genomics 2007, 32(1):45-57.
61. Frosen J, Piippo A, Paetau A, Kangasniemi M, Niemela M, Hernesniemi J, Jaaskelainen J: Growth factor receptor expression and remodeling of saccular cerebral artery aneurysm walls: implications for biological therapy preventing rupture. Neurosurgery 2006, 58(3):534-541. discussion 534-541.
62. Ruigrok YM, Baas AF, Medic J, Wijmenga C, Rinkel GJ: The transforming growth factor-beta receptor genes and the risk of intracranial aneurysms. Int J Stroke 2012, 7(8):645-648.
63. Peters DG, Kassam AB, Feingold E, Heidrich-O'Hare E, Yonas H, Ferrell RE, Brufsky A: Molecular anatomy of an intracranial aneurysm: coordinated expression of genes involved in wound healing and tissue remodeling. Stroke 2001, 32(4):1036-1042.