메뉴 건너뛰기




Volumn 76, Issue 8, 2016, Pages 2105-2114

Transcriptome Analysis of Triple-Negative Breast Cancer Reveals an Integrated mRNA-lncRNA Signature with Predictive and Prognostic Value

Author keywords

[No Author keywords available]

Indexed keywords

LONG UNTRANSLATED RNA; MESSENGER RNA; PACLITAXEL; TAXANE DERIVATIVE; TRANSCRIPTOME;

EID: 84965029321     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-3284     Document Type: Review
Times cited : (169)

References (45)
  • 2
    • 76749131688 scopus 로고    scopus 로고
    • Triple-negative/basal-like breast cancer: Clinical, pathologic and molecular features
    • Venkitaraman R. Triple-negative/basal-like breast cancer: clinical, pathologic and molecular features. Expert Rev Anticancer Ther 2010;10:199-207.
    • (2010) Expert Rev Anticancer Ther , vol.10 , pp. 199-207
    • Venkitaraman, R.1
  • 3
    • 78649663247 scopus 로고    scopus 로고
    • Triple-negative breast cancer: Disease entity or title of convenience?
    • Carey L, Winer E, Viale G, Cameron D, Gianni L. Triple-negative breast cancer: disease entity or title of convenience? Nat Rev Clin Oncol 2010; 7:683-92.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 683-692
    • Carey, L.1    Winer, E.2    Viale, G.3    Cameron, D.4    Gianni, L.5
  • 4
    • 67349217988 scopus 로고    scopus 로고
    • Clinicopathological features of the triple-negative tumors in Chinese breast cancer patients
    • Yin WJ, Lu JS, Di GH, Lin YP, Zhou LH, Liu GY, et al. Clinicopathological features of the triple-negative tumors in Chinese breast cancer patients. Breast Cancer Res Treat 2009;115:325-33.
    • (2009) Breast Cancer Res Treat , vol.115 , pp. 325-333
    • Yin, W.J.1    Lu, J.S.2    Di, G.H.3    Lin, Y.P.4    Zhou, L.H.5    Liu, G.Y.6
  • 6
    • 79960015997 scopus 로고    scopus 로고
    • Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
    • Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, Shyr Y, et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest 2011; 121:2750-67.
    • (2011) J Clin Invest , vol.121 , pp. 2750-2767
    • Lehmann, B.D.1    Bauer, J.A.2    Chen, X.3    Sanders, M.E.4    Chakravarthy, A.B.5    Shyr, Y.6
  • 7
    • 84905401266 scopus 로고    scopus 로고
    • Genome-wide mapping and characterization of notch-regulated long noncoding RNAs in acute leukemia
    • Trimarchi T, Bilal E, Ntziachristos P, Fabbri G, Dalla-Favera R, Tsirigos A, et al. Genome-wide mapping and characterization of notch-regulated long noncoding RNAs in acute leukemia. Cell 2014;158:593-606.
    • (2014) Cell , vol.158 , pp. 593-606
    • Trimarchi, T.1    Bilal, E.2    Ntziachristos, P.3    Fabbri, G.4    Dalla-Favera, R.5    Tsirigos, A.6
  • 8
    • 80053045739 scopus 로고    scopus 로고
    • Molecular mechanisms of long noncoding RNAs
    • Wang KC, Chang HY. Molecular mechanisms of long noncoding RNAs. Mol Cell 2011;43:904-14.
    • (2011) Mol Cell , vol.43 , pp. 904-914
    • Wang, K.C.1    Chang, H.Y.2
  • 9
    • 82155186923 scopus 로고    scopus 로고
    • The emergence of lncRNAs in cancer biology
    • Prensner JR, Chinnaiyan AM. The emergence of lncRNAs in cancer biology. Cancer Discov 2011;1:391-407.
    • (2011) Cancer Discov , vol.1 , pp. 391-407
    • Prensner, J.R.1    Chinnaiyan, A.M.2
  • 10
    • 77951118936 scopus 로고    scopus 로고
    • Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
    • Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 2010;464:1071-6.
    • (2010) Nature , vol.464 , pp. 1071-1076
    • Gupta, R.A.1    Shah, N.2    Wang, K.C.3    Kim, J.4    Horlings, H.M.5    Wong, D.J.6
  • 12
    • 84938988506 scopus 로고    scopus 로고
    • Long noncoding RNA MALAT1 promotes aggressive renal cell carcinoma through Ezh2 and interacts with miR-205
    • Hirata H, Hinoda Y, Shahryari V, Deng G, Nakajima K, Tabatabai ZL, et al. Long noncoding RNA MALAT1 promotes aggressive renal cell carcinoma through Ezh2 and interacts with miR-205. Cancer Res 2015;75:1322-31.
    • (2015) Cancer Res , vol.75 , pp. 1322-1331
    • Hirata, H.1    Hinoda, Y.2    Shahryari, V.3    Deng, G.4    Nakajima, K.5    Tabatabai, Z.L.6
  • 13
    • 84893701149 scopus 로고    scopus 로고
    • LncRNA profile study reveals a three-lncRNA signature associated with the survival of patients with oesophageal squamous cell carcinoma
    • Li J, Chen Z, Tian L, Zhou C, He MY, Gao Y, et al. LncRNA profile study reveals a three-lncRNA signature associated with the survival of patients with oesophageal squamous cell carcinoma. Gut 2014;63:1700-10.
    • (2014) Gut , vol.63 , pp. 1700-1710
    • Li, J.1    Chen, Z.2    Tian, L.3    Zhou, C.4    He, M.Y.5    Gao, Y.6
  • 14
    • 80055046798 scopus 로고    scopus 로고
    • Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans
    • Yang F, Zhang L, Huo XS, Yuan JH, Xu D, Yuan SX, et al. Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans. Hepatology 2011;54: 1679-89.
    • (2011) Hepatology , vol.54 , pp. 1679-1689
    • Yang, F.1    Zhang, L.2    Huo, X.S.3    Yuan, J.H.4    Xu, D.5    Yuan, S.X.6
  • 15
    • 84933500899 scopus 로고    scopus 로고
    • Cisplatin plus gemcitabine versus paclitaxel plus gemcitabine as first-line therapy for metastatic triple-negative breast cancer (cbcsg006): A randomised, openlabel, multicentre, phase 3 trial
    • Hu XC, Zhang J, Xu BH, Cai L, Ragaz J, Wang ZH, et al. Cisplatin plus gemcitabine versus paclitaxel plus gemcitabine as first-line therapy for metastatic triple-negative breast cancer (CBCSG006): a randomised, openlabel, multicentre, phase 3 trial. Lancet Oncol 2015;16:436-46.
    • (2015) Lancet Oncol , vol.16 , pp. 436-446
    • Hu, X.C.1    Zhang, J.2    Xu, B.H.3    Cai, L.4    Ragaz, J.5    Wang, Z.H.6
  • 16
    • 84900851474 scopus 로고    scopus 로고
    • Enriched variations in tekt4 and breast cancer resistance to paclitaxel
    • Jiang YZ, Yu KD, Peng WT, Di GH, Wu J, Liu GY, et al. Enriched variations in TEKT4 and breast cancer resistance to paclitaxel. Nat Commun 2014;5:3802.
    • (2014) Nat Commun , vol.5 , pp. 3802
    • Jiang, Y.Z.1    Yu, K.D.2    Peng, W.T.3    Di, G.H.4    Wu, J.5    Liu, G.Y.6
  • 17
    • 84890624762 scopus 로고    scopus 로고
    • The residual tumor autophagy marker lc3b serves as a prognostic marker in local advanced breast cancer after neoadjuvant chemotherapy
    • Chen S, Jiang YZ, Huang L, Zhou RJ, Yu KD, Liu Y, et al. The residual tumor autophagy marker LC3B serves as a prognostic marker in local advanced breast cancer after neoadjuvant chemotherapy. Clin Cancer Res 2013;19: 6853-62.
    • (2013) Clin Cancer Res , vol.19 , pp. 6853-6862
    • Chen, S.1    Jiang, Y.Z.2    Huang, L.3    Zhou, R.J.4    Yu, K.D.5    Liu, Y.6
  • 18
    • 84903973462 scopus 로고    scopus 로고
    • Favorable prognostic impact in loss of tp53 and pik3ca mutations after neoadjuvant chemotherapy in breast cancer
    • Jiang YZ, Yu KD, Bao J, Peng WT, Shao ZM. Favorable prognostic impact in loss of TP53 and PIK3CA mutations after neoadjuvant chemotherapy in breast cancer. Cancer Res 2014;74:3399-407.
    • (2014) Cancer Res , vol.74 , pp. 3399-3407
    • Jiang, Y.Z.1    Yu, K.D.2    Bao, J.3    Peng, W.T.4    Shao, Z.M.5
  • 19
    • 84893821461 scopus 로고    scopus 로고
    • Comparative proteome analysis revealing an 11-protein signature for aggressive triple-negative breast cancer
    • djt376
    • Liu NQ, Stingl C, Look MP, Smid M, Braakman RB, De Marchi T, et al. Comparative proteome analysis revealing an 11-protein signature for aggressive triple-negative breast cancer. J Natl Cancer Inst 2014;106: djt376.
    • (2014) J Natl Cancer Inst , vol.106
    • Liu, N.Q.1    Stingl, C.2    Look, M.P.3    Smid, M.4    Braakman, R.B.5    De Marchi, T.6
  • 20
    • 84888135550 scopus 로고    scopus 로고
    • Prognostic and predictive value of a microrna signature in stage II colon cancer: A microrna expression analysis
    • Zhang JX, Song W, Chen ZH, Wei JH, Liao YJ, Lei J, et al. Prognostic and predictive value of a microRNA signature in stage II colon cancer: a microRNA expression analysis. Lancet Oncol 2013;14:1295-306.
    • (2013) Lancet Oncol , vol.14 , pp. 1295-1306
    • Zhang, J.X.1    Song, W.2    Chen, Z.H.3    Wei, J.H.4    Liao, Y.J.5    Lei, J.6
  • 21
    • 84861572492 scopus 로고    scopus 로고
    • Prognostic value of a microrna signature in nasopharyngeal carcinoma: A microrna expression analysis
    • Liu N, Chen NY, Cui RX, Li WF, Li Y, Wei RR, et al. Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis. Lancet Oncol 2012;13:633-41.
    • (2012) Lancet Oncol , vol.13 , pp. 633-641
    • Liu, N.1    Chen, N.Y.2    Cui, R.X.3    Li, W.F.4    Li, Y.5    Wei, R.R.6
  • 23
    • 79960714772 scopus 로고    scopus 로고
    • Use of integrative epigenetic and cytogenetic analyses to identify novel tumor-suppressor genes in malignant melanoma
    • Mithani SK, Smith IM, Califano JA. Use of integrative epigenetic and cytogenetic analyses to identify novel tumor-suppressor genes in malignant melanoma. Melanoma Res 2011;21:298-307.
    • (2011) Melanoma Res , vol.21 , pp. 298-307
    • Mithani, S.K.1    Smith, I.M.2    Califano, J.A.3
  • 24
    • 84880652927 scopus 로고    scopus 로고
    • Targeting long non-coding RNA to therapeutically upregulate gene expression
    • Wahlestedt C. Targeting long non-coding RNA to therapeutically upregulate gene expression. Nat Rev Drug Discov 2013;12:433-46.
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 433-446
    • Wahlestedt, C.1
  • 25
    • 84887101163 scopus 로고    scopus 로고
    • MicroRNAs and other non-coding RNAs as targets for anticancer drug development
    • Ling H, Fabbri M, Calin GA. MicroRNAs and other non-coding RNAs as targets for anticancer drug development. Nat Rev Drug Discov 2013;12: 847-65.
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 847-865
    • Ling, H.1    Fabbri, M.2    Calin, G.A.3
  • 26
    • 84928608163 scopus 로고    scopus 로고
    • Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes
    • Su X, Malouf GG, Chen Y, Zhang J, Yao H, Valero V, et al. Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes. Oncotarget 2014;5:9864-76.
    • (2014) Oncotarget , vol.5 , pp. 9864-9876
    • Su, X.1    Malouf, G.G.2    Chen, Y.3    Zhang, J.4    Yao, H.5    Valero, V.6
  • 27
    • 84944077358 scopus 로고    scopus 로고
    • Comprehensive genomic characterization of long non-coding RNAs across human cancers
    • Yan X, Hu Z, Feng Y, Hu X, Yuan J, Zhao SD, et al. Comprehensive genomic characterization of long non-coding RNAs across human cancers. Cancer Cell 2015;28:529-40.
    • (2015) Cancer Cell , vol.28 , pp. 529-540
    • Yan, X.1    Hu, Z.2    Feng, Y.3    Hu, X.4    Yuan, J.5    Zhao, S.D.6
  • 28
    • 0642275613 scopus 로고    scopus 로고
    • aHIF but not HIF-1alpha transcript is a poor prognostic marker in human breast cancer
    • Cayre A, Rossignol F, Clottes E, Penault-Llorca F. aHIF but not HIF-1alpha transcript is a poor prognostic marker in human breast cancer. Breast Cancer Res 2003;5:R223-30.
    • (2003) Breast Cancer Res , vol.5 , pp. R223-R230
    • Cayre, A.1    Rossignol, F.2    Clottes, E.3    Penault-Llorca, F.4
  • 30
    • 2442576104 scopus 로고    scopus 로고
    • Natural antisense transcripts of hypoxiainducible factor 1alpha are detected in different normal and tumour human tissues
    • Rossignol F, Vache C, Clottes E. Natural antisense transcripts of hypoxiainducible factor 1alpha are detected in different normal and tumour human tissues. Gene 2002;299:135-40.
    • (2002) Gene , vol.299 , pp. 135-140
    • Rossignol, F.1    Vache, C.2    Clottes, E.3
  • 31
    • 0033585496 scopus 로고    scopus 로고
    • Ahif: A natural antisense transcript overexpressed in human renal cancer and during hypoxia
    • Thrash-Bingham CA, Tartof KD. aHIF: a natural antisense transcript overexpressed in human renal cancer and during hypoxia. J Natl Cancer Inst 1999;91:143-51.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 143-151
    • Thrash-Bingham, C.A.1    Tartof, K.D.2
  • 32
    • 84906831542 scopus 로고    scopus 로고
    • Chk1-induced CCNB1 overexpression promotes cell proliferation and tumor growth in human colorectal cancer
    • Fang Y, Yu H, Liang X, Xu J, Cai X. Chk1-induced CCNB1 overexpression promotes cell proliferation and tumor growth in human colorectal cancer. Cancer Biol Ther 2014;15:1268-79.
    • (2014) Cancer Biol Ther , vol.15 , pp. 1268-1279
    • Fang, Y.1    Yu, H.2    Liang, X.3    Xu, J.4    Cai, X.5
  • 33
    • 79960131390 scopus 로고    scopus 로고
    • Integrin subunits alpha5 and alpha6 regulate cell cycle by modulating the chk1 and Rb/E2F pathways to affect breast cancer metastasis
    • Wang Y, Shenouda S, Baranwal S, Rathinam R, Jain P, Bao L, et al. Integrin subunits alpha5 and alpha6 regulate cell cycle by modulating the chk1 and Rb/E2F pathways to affect breast cancer metastasis. Mol Cancer 2011; 10:84.
    • (2011) Mol Cancer , vol.10 , pp. 84
    • Wang, Y.1    Shenouda, S.2    Baranwal, S.3    Rathinam, R.4    Jain, P.5    Bao, L.6
  • 34
    • 84874775434 scopus 로고    scopus 로고
    • Suppressed miR-424 expression via upregulation of target gene Chk1 contributes to the progression of cervical cancer
    • Xu J, Li Y, Wang F, Wang X, Cheng B, Ye F, et al. Suppressed miR-424 expression via upregulation of target gene Chk1 contributes to the progression of cervical cancer. Oncogene 2013;32:976-87.
    • (2013) Oncogene , vol.32 , pp. 976-987
    • Xu, J.1    Li, Y.2    Wang, F.3    Wang, X.4    Cheng, B.5    Ye, F.6
  • 35
    • 84881100081 scopus 로고    scopus 로고
    • HY-1 induces G(2)/M cell cycle arrest in human colon cancer cells through the ATR-Chk1-Cdc25C and Weel pathways
    • Zhao Y, Wu Z, Zhang Y, Zhu L. HY-1 induces G(2)/M cell cycle arrest in human colon cancer cells through the ATR-Chk1-Cdc25C and Weel pathways. Cancer Sci 2013;104:1062-6.
    • (2013) Cancer Sci , Issue.104 , pp. 1062-1066
    • Zhao, Y.1    Wu, Z.2    Zhang, Y.3    Zhu, L.4
  • 37
    • 84928698046 scopus 로고    scopus 로고
    • Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy response
    • Al-Kaabi MM, Alshareeda AT, Jerjees DA, Muftah AA, Green AR, Alsubhi NH, et al. Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy response. Br J Cancer 2015; 112:901-11.
    • (2015) Br J Cancer , vol.112 , pp. 901-911
    • Al-Kaabi, M.M.1    Alshareeda, A.T.2    Jerjees, D.A.3    Muftah, A.A.4    Green, A.R.5    Alsubhi, N.H.6
  • 39
    • 84942361015 scopus 로고    scopus 로고
    • Interleukin-8 induces expression of FOXC1 to promote trans-activation of CXCR1 and CCL2 in hepatocellular carcinoma cell lines and formation of metastases in mice
    • Huang W, Chen Z, Zhang L, Tian D, Wang D, Fan D, et al. Interleukin-8 induces expression of FOXC1 to promote trans-activation of CXCR1 and CCL2 in hepatocellular carcinoma cell lines and formation of metastases in mice. Gastroenterology 2015;149:1053-67.
    • (2015) Gastroenterology , vol.149 , pp. 1053-1067
    • Huang, W.1    Chen, Z.2    Zhang, L.3    Tian, D.4    Wang, D.5    Fan, D.6
  • 40
    • 84965007927 scopus 로고    scopus 로고
    • Mek-dependent il-8 induction regulates the invasiveness of triple-negative breast cancer cells
    • Nov4. [Epub ahead of print]
    • Kim S, Lee J, Jeon M, Lee JE, Nam SJ. MEK-dependent IL-8 induction regulates the invasiveness of triple-negative breast cancer cells. Tumour Biol . 2015 Nov 4. [Epub ahead of print].
    • (2015) Tumour Biol
    • Kim, S.1    Lee, J.2    Jeon, M.3    Lee, J.E.4    Nam, S.J.5
  • 41
    • 84863982875 scopus 로고    scopus 로고
    • SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors
    • Montagner M, Enzo E, Forcato M, Zanconato F, Parenti A, Rampazzo E, et al. SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors. Nature 2012; 487:380-4.
    • (2012) Nature , vol.487 , pp. 380-384
    • Montagner, M.1    Enzo, E.2    Forcato, M.3    Zanconato, F.4    Parenti, A.5    Rampazzo, E.6
  • 42
    • 84930084705 scopus 로고    scopus 로고
    • Interleukin-8 upregulates integrin b3 expression and promotes estrogen receptor-negative breast cancer cell invasion by activating the PI3K/Akt/NF-kB pathway
    • Shao N, Lu Z, Zhang Y, Wang M, Li W, Hu Z, et al. Interleukin-8 upregulates integrin b3 expression and promotes estrogen receptor-negative breast cancer cell invasion by activating the PI3K/Akt/NF-kB pathway. Cancer Lett 2015;364:165-72.
    • (2015) Cancer Lett , vol.364 , pp. 165-172
    • Shao, N.1    Lu, Z.2    Zhang, Y.3    Wang, M.4    Li, W.5    Hu, Z.6
  • 43
    • 84921411055 scopus 로고    scopus 로고
    • The anti-androgen drug dutasteride renders triple negative breast cancer cells more sensitive to chemotherapy via inhibition of hif-1a-/vegfsignaling
    • von Wahlde MK, Hulsewig C, Ruckert C, Gotte M, Kiesel L, Bernemann C. The anti-androgen drug dutasteride renders triple negative breast cancer cells more sensitive to chemotherapy via inhibition of HIF-1a-/VEGFsignaling. Gynecol Endocrinol 2015;31:160-4.
    • (2015) Gynecol Endocrinol , vol.31 , pp. 160-164
    • Von Wahlde, M.K.1    Hulsewig, C.2    Ruckert, C.3    Gotte, M.4    Kiesel, L.5    Bernemann, C.6
  • 44
    • 84885763308 scopus 로고    scopus 로고
    • Hypoxia induced multidrug resistance of laryngeal cancer cells via hypoxia-inducible factor-1a
    • Li DW, Dong P, Wang F, Chen XW, Xu CZ, Zhou L. Hypoxia induced multidrug resistance of laryngeal cancer cells via hypoxia-inducible factor-1a. Asian Pac J Cancer Prev 2013;14:4853-8.
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 4853-4858
    • Li, D.W.1    Dong, P.2    Wang, F.3    Chen, X.W.4    Xu, C.Z.5    Zhou, L.6
  • 45
    • 77955768685 scopus 로고    scopus 로고
    • Actin-sequestering protein, thymosin beta-4, induces paclitaxel resistance through ros/hif-1alpha stabilization in hela human cervical tumor cells
    • Oh J.M. , MoonE.Y.actin-sequestering protein, thymosin beta-4, induces paclitaxel resistance through ros/hif-1alpha stabilization in hela human cervical tumor cells. Life Sci2010;87:286-293
    • (2010) Life Sci , vol.87 , pp. 286-293
    • Oh, J.M.1    Moon, E.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.