-
1
-
-
84871211326
-
Pathobiology of pulmonary arterial hypertension and right ventricular failure
-
N.F. Voelkel, J. Gomez-Arroyo, A. Abbate, H.J. Bogaard, and M.R. Nicolls Pathobiology of pulmonary arterial hypertension and right ventricular failure Eur. Respir. J. 40 2012 1555 1565
-
(2012)
Eur. Respir. J.
, vol.40
, pp. 1555-1565
-
-
Voelkel, N.F.1
Gomez-Arroyo, J.2
Abbate, A.3
Bogaard, H.J.4
Nicolls, M.R.5
-
3
-
-
26444534291
-
Sildenafil citrate therapy for pulmonary arterial hypertension
-
N. Galie, H.A. Ghofrani, A. Torbicki, R.J. Barst, L.J. Rubin, D. Badesch, T. Fleming, T. Parpia, G. Burgess, A. Branzi, F. Grimminger, M. Kurzyna, and G. Simonneau Sildenafil citrate therapy for pulmonary arterial hypertension N. Engl. J. Med. 353 2005 2148 2157
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 2148-2157
-
-
Galie, N.1
Ghofrani, H.A.2
Torbicki, A.3
Barst, R.J.4
Rubin, L.J.5
Badesch, D.6
Fleming, T.7
Parpia, T.8
Burgess, G.9
Branzi, A.10
Grimminger, F.11
Kurzyna, M.12
Simonneau, G.13
-
4
-
-
77950878463
-
Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline
-
P. Caruso, M.R. MacLean, R. Khanin, J. McClure, E. Soon, M. Southgate, R.A. MacDonald, J.A. Greig, K.E. Robertson, R. Masson, L. Denby, Y. Dempsie, L. Long, N.W. Morrell, and A.H. Baker Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline Arterioscler. Thromb. Vasc. Biol. 30 2010 716 723
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 716-723
-
-
Caruso, P.1
MacLean, M.R.2
Khanin, R.3
McClure, J.4
Soon, E.5
Southgate, M.6
MacDonald, R.A.7
Greig, J.A.8
Robertson, K.E.9
Masson, R.10
Denby, L.11
Dempsie, Y.12
Long, L.13
Morrell, N.W.14
Baker, A.H.15
-
5
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
6
-
-
84925243798
-
MicroRNAs in pulmonary arterial hypertension: Pathogenesis, diagnosis and treatment
-
J. Bienertova-Vasku, J. Novak, and A. Vasku MicroRNAs in pulmonary arterial hypertension: pathogenesis, diagnosis and treatment J. Am. Soc. Hypertens. 9 2015 221 234
-
(2015)
J. Am. Soc. Hypertens.
, vol.9
, pp. 221-234
-
-
Bienertova-Vasku, J.1
Novak, J.2
Vasku, A.3
-
7
-
-
33947520124
-
P53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload
-
M. Sano, T. Minamino, H. Toko, H. Miyauchi, M. Orimo, Y. Qin, H. Akazawa, K. Tateno, Y. Kayama, M. Harada, I. Shimizu, T. Asahara, H. Hamada, S. Tomita, J.D. Molkentin, Y. Zou, and I. Komuro p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload Nature 446 2007 444 448
-
(2007)
Nature
, vol.446
, pp. 444-448
-
-
Sano, M.1
Minamino, T.2
Toko, H.3
Miyauchi, H.4
Orimo, M.5
Qin, Y.6
Akazawa, H.7
Tateno, K.8
Kayama, Y.9
Harada, M.10
Shimizu, I.11
Asahara, T.12
Hamada, H.13
Tomita, S.14
Molkentin, J.D.15
Zou, Y.16
Komuro, I.17
-
8
-
-
84865853420
-
MicroRNA-199a-5p is associated with hypoxia-inducible factor-1alpha expression in lungs from patients with COPD
-
S. Mizuno, H.J. Bogaard, J. Gomez-Arroyo, A. Alhussaini, D. Kraskauskas, C.D. Cool, and N.F. Voelkel MicroRNA-199a-5p is associated with hypoxia-inducible factor-1alpha expression in lungs from patients with COPD Chest 142 2012 663 672
-
(2012)
Chest
, vol.142
, pp. 663-672
-
-
Mizuno, S.1
Bogaard, H.J.2
Gomez-Arroyo, J.3
Alhussaini, A.4
Kraskauskas, D.5
Cool, C.D.6
Voelkel, N.F.7
-
9
-
-
84895521111
-
Circulating miR-29a, among other up-regulated microRNAs, is the only biomarker for both hypertrophy and fibrosis in patients with hypertrophic cardiomyopathy
-
R. Roncarati, C. Viviani Anselmi, M.A. Losi, L. Papa, E. Cavarretta, P. Da Costa Martins, C. Contaldi, G. Saccani Jotti, A. Franzone, L. Galastri, M.V. Latronico, M. Imbriaco, G. Esposito, L. De Windt, S. Betocchi, and G. Condorelli Circulating miR-29a, among other up-regulated microRNAs, is the only biomarker for both hypertrophy and fibrosis in patients with hypertrophic cardiomyopathy J. Am. Coll. Cardiol. 63 2014 920 927
-
(2014)
J. Am. Coll. Cardiol.
, vol.63
, pp. 920-927
-
-
Roncarati, R.1
Viviani Anselmi, C.2
Losi, M.A.3
Papa, L.4
Cavarretta, E.5
Da Costa Martins, P.6
Contaldi, C.7
Saccani Jotti, G.8
Franzone, A.9
Galastri, L.10
Latronico, M.V.11
Imbriaco, M.12
Esposito, G.13
De Windt, L.14
Betocchi, S.15
Condorelli, G.16
-
10
-
-
84890011341
-
Transforming growth factor-beta(1) represses bone morphogenetic protein-mediated Smad signaling in pulmonary artery smooth muscle cells via Smad3
-
P.D. Upton, R.J. Davies, T. Tajsic, and N.W. Morrell Transforming growth factor-beta(1) represses bone morphogenetic protein-mediated Smad signaling in pulmonary artery smooth muscle cells via Smad3 Am. J. Respir. Cell Mol. Biol. 49 2013 1135 1145
-
(2013)
Am. J. Respir. Cell Mol. Biol.
, vol.49
, pp. 1135-1145
-
-
Upton, P.D.1
Davies, R.J.2
Tajsic, T.3
Morrell, N.W.4
-
11
-
-
84924755766
-
Loss of microRNA-17 approximately 92 in smooth muscle cells attenuates experimental pulmonary hypertension via induction of PDZ and LIM domain 5
-
T. Chen, G. Zhou, Q. Zhou, H. Tang, J.C. Ibe, H. Cheng, D. Gou, J. Chen, J.X. Yuan, and J.U. Raj Loss of microRNA-17 approximately 92 in smooth muscle cells attenuates experimental pulmonary hypertension via induction of PDZ and LIM domain 5 Am. J. Respir. Crit. Care Med. 191 2015 678 692
-
(2015)
Am. J. Respir. Crit. Care Med.
, vol.191
, pp. 678-692
-
-
Chen, T.1
Zhou, G.2
Zhou, Q.3
Tang, H.4
Ibe, J.C.5
Cheng, H.6
Gou, D.7
Chen, J.8
Yuan, J.X.9
Raj, J.U.10
-
12
-
-
84455168708
-
Altered microRNA processing in heritable pulmonary arterial hypertension: An important role for Smad-8
-
K.M. Drake, D. Zygmunt, L. Mavrakis, P. Harbor, L. Wang, S.A. Comhair, S.C. Erzurum, and M.A. Aldred Altered microRNA processing in heritable pulmonary arterial hypertension: an important role for Smad-8 Am. J. Respir. Crit. Care Med. 184 2011 1400 1408
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.184
, pp. 1400-1408
-
-
Drake, K.M.1
Zygmunt, D.2
Mavrakis, L.3
Harbor, P.4
Wang, L.5
Comhair, S.A.6
Erzurum, S.C.7
Aldred, M.A.8
-
13
-
-
77955484492
-
Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha
-
B.N. Davis, A.C. Hilyard, P.H. Nguyen, G. Lagna, and A. Hata Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha Mol. Cell 39 2010 373 384
-
(2010)
Mol. Cell
, vol.39
, pp. 373-384
-
-
Davis, B.N.1
Hilyard, A.C.2
Nguyen, P.H.3
Lagna, G.4
Hata, A.5
-
14
-
-
24644492790
-
The role of increased pulmonary blood flow in pulmonary arterial hypertension
-
M.E. van Albada, R.G. Schoemaker, M.S. Kemna, A.H. Cromme-Dijkhuis, R. van Veghel, and R.M. Berger The role of increased pulmonary blood flow in pulmonary arterial hypertension Eur. Respir. J. 26 2005 487 493
-
(2005)
Eur. Respir. J.
, vol.26
, pp. 487-493
-
-
Van Albada, M.E.1
Schoemaker, R.G.2
Kemna, M.S.3
Cromme-Dijkhuis, A.H.4
Van Veghel, R.5
Berger, R.M.6
-
15
-
-
0035020086
-
Nitric oxide attenuates H(2)O(2)-induced endothelial barrier dysfunction: Mechanisms of protection
-
M.P. Gupta, M.D. Ober, C. Patterson, M. Al-Hassani, V. Natarajan, and C.M. Hart Nitric oxide attenuates H(2)O(2)-induced endothelial barrier dysfunction: mechanisms of protection Am. J. Physiol. Lung Cell Mol. Physiol. 280 2001 L116 L126
-
(2001)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.280
, pp. L116-L126
-
-
Gupta, M.P.1
Ober, M.D.2
Patterson, C.3
Al-Hassani, M.4
Natarajan, V.5
Hart, C.M.6
-
16
-
-
84940482569
-
The key target of neuroprotection after the onset of ischemic stroke: Secretory pathway Ca(2+)-ATPase 1
-
L.H. Li, X.R. Tian, and Z.P. Hu The key target of neuroprotection after the onset of ischemic stroke: secretory pathway Ca(2+)-ATPase 1 Neural Regen. Res. 10 2015 1271 1278
-
(2015)
Neural Regen. Res.
, vol.10
, pp. 1271-1278
-
-
Li, L.H.1
Tian, X.R.2
Hu, Z.P.3
-
17
-
-
84885055633
-
Nuclear factor kappa-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension
-
L.C. Price, G. Caramori, F. Perros, C. Meng, N. Gambaryan, P. Dorfmuller, D. Montani, P. Casolari, J. Zhu, K. Dimopoulos, D. Shao, B. Girerd, S. Mumby, A. Proudfoot, M. Griffiths, A. Papi, M. Humbert, I.M. Adcock, and S.J. Wort Nuclear factor kappa-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension PLoS One 8 2013 e75415
-
(2013)
PLoS One
, vol.8
-
-
Price, L.C.1
Caramori, G.2
Perros, F.3
Meng, C.4
Gambaryan, N.5
Dorfmuller, P.6
Montani, D.7
Casolari, P.8
Zhu, J.9
Dimopoulos, K.10
Shao, D.11
Girerd, B.12
Mumby, S.13
Proudfoot, A.14
Griffiths, M.15
Papi, A.16
Humbert, M.17
Adcock, I.M.18
Wort, S.J.19
-
18
-
-
84877783446
-
MicroRNA-138 plays a role in hypoxic pulmonary vascular remodelling by targeting Mst1
-
S. Li, Y. Ran, D. Zhang, J. Chen, and D. Zhu MicroRNA-138 plays a role in hypoxic pulmonary vascular remodelling by targeting Mst1 Biochem. J. 452 2013 281 291
-
(2013)
Biochem. J.
, vol.452
, pp. 281-291
-
-
Li, S.1
Ran, Y.2
Zhang, D.3
Chen, J.4
Zhu, D.5
-
19
-
-
84892943787
-
MicroRNA-138 regulates hypoxia-induced endothelial cell dysfunction by targeting S100A1
-
A. Sen, S. Ren, C. Lerchenmuller, J. Sun, N. Weiss, P. Most, and K. Peppel MicroRNA-138 regulates hypoxia-induced endothelial cell dysfunction by targeting S100A1 PLoS One 8 2013 e78684
-
(2013)
PLoS One
, vol.8
-
-
Sen, A.1
Ren, S.2
Lerchenmuller, C.3
Sun, J.4
Weiss, N.5
Most, P.6
Peppel, K.7
-
20
-
-
84888004362
-
MiR-199a-5p promotes migration and tube formation of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and eNOS
-
S. Zhang, L. Liu, R. Wang, H. Tuo, Y. Guo, L. Yi, J. Wang, and D. Wang MiR-199a-5p promotes migration and tube formation of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and eNOS Arch. Virol. 158 2013 2443 2452
-
(2013)
Arch. Virol.
, vol.158
, pp. 2443-2452
-
-
Zhang, S.1
Liu, L.2
Wang, R.3
Tuo, H.4
Guo, Y.5
Yi, L.6
Wang, J.7
Wang, D.8
-
21
-
-
77956533696
-
MicroRNAs are dynamically regulated in hypertrophic hearts, and miR-199a is essential for the maintenance of cell size in cardiomyocytes
-
X.W. Song, Q. Li, L. Lin, X.C. Wang, D.F. Li, G.K. Wang, A.J. Ren, Y.R. Wang, Y.W. Qin, W.J. Yuan, and Q. Jing MicroRNAs are dynamically regulated in hypertrophic hearts, and miR-199a is essential for the maintenance of cell size in cardiomyocytes J. Cell Physiol. 225 2010 437 443
-
(2010)
J. Cell Physiol.
, vol.225
, pp. 437-443
-
-
Song, X.W.1
Li, Q.2
Lin, L.3
Wang, X.C.4
Li, D.F.5
Wang, G.K.6
Ren, A.J.7
Wang, Y.R.8
Qin, Y.W.9
Yuan, W.J.10
Jing, Q.11
-
22
-
-
84900789644
-
MicroRNA-199a-5p affects porcine preadipocyte proliferation and differentiation
-
X.E. Shi, Y.F. Li, L. Jia, H.L. Ji, Z.Y. Song, J. Cheng, G.F. Wu, C.C. Song, Q.L. Zhang, J.Y. Zhu, and G.S. Yang MicroRNA-199a-5p affects porcine preadipocyte proliferation and differentiation Int. J. Mol. Sci. 15 2014 8526 8538
-
(2014)
Int. J. Mol. Sci.
, vol.15
, pp. 8526-8538
-
-
Shi, X.E.1
Li, Y.F.2
Jia, L.3
Ji, H.L.4
Song, Z.Y.5
Cheng, J.6
Wu, G.F.7
Song, C.C.8
Zhang, Q.L.9
Zhu, J.Y.10
Yang, G.S.11
-
23
-
-
84867525253
-
Functional screening for miRNAs targeting Smad4 identified miR-199a as a negative regulator of TGF-beta signalling pathway
-
Y. Zhang, K.J. Fan, Q. Sun, A.Z. Chen, W.L. Shen, Z.H. Zhao, X.F. Zheng, and X. Yang Functional screening for miRNAs targeting Smad4 identified miR-199a as a negative regulator of TGF-beta signalling pathway Nucleic Acids Res. 40 2012 9286 9297
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 9286-9297
-
-
Zhang, Y.1
Fan, K.J.2
Sun, Q.3
Chen, A.Z.4
Shen, W.L.5
Zhao, Z.H.6
Zheng, X.F.7
Yang, X.8
-
24
-
-
0034678908
-
Transcriptional control by the TGF-β/Smad signaling system
-
J. Massagué, and D. Wotton Transcriptional control by the TGF-β/Smad signaling system EMBO J. 19 2000 1745 1754
-
(2000)
EMBO J.
, vol.19
, pp. 1745-1754
-
-
Massagué, J.1
Wotton, D.2
-
25
-
-
34250176894
-
The transforming growth factor-beta/Smad2,3 signalling axis is impaired in experimental pulmonary hypertension
-
A. Zakrzewicz, F.M. Kouri, B. Nejman, G. Kwapiszewska, M. Hecker, R. Sandu, E. Dony, W. Seeger, R.T. Schermuly, O. Eickelberg, and R.E. Morty The transforming growth factor-beta/Smad2,3 signalling axis is impaired in experimental pulmonary hypertension Eur. Respir. J. 29 2007 1094 1104
-
(2007)
Eur. Respir. J.
, vol.29
, pp. 1094-1104
-
-
Zakrzewicz, A.1
Kouri, F.M.2
Nejman, B.3
Kwapiszewska, G.4
Hecker, M.5
Sandu, R.6
Dony, E.7
Seeger, W.8
Schermuly, R.T.9
Eickelberg, O.10
Morty, R.E.11
-
26
-
-
84911863805
-
Serotonin drives the activation of pulmonary artery adventitial fibroblasts and TGF-beta1/Smad3-mediated fibrotic responses through 5-HT(2A) receptors
-
C. Chen, X. Han, F. Fan, Y. Liu, T. Wang, J. Wang, P. Hu, A. Ma, and H. Tian Serotonin drives the activation of pulmonary artery adventitial fibroblasts and TGF-beta1/Smad3-mediated fibrotic responses through 5-HT(2A) receptors Mol. Cell Biochem. 397 2014 267 276
-
(2014)
Mol. Cell Biochem.
, vol.397
, pp. 267-276
-
-
Chen, C.1
Han, X.2
Fan, F.3
Liu, Y.4
Wang, T.5
Wang, J.6
Hu, P.7
Ma, A.8
Tian, H.9
-
27
-
-
84927176114
-
Transforming growth factor beta-at the centre of systemic sclerosis
-
R. Lafyatis Transforming growth factor beta-at the centre of systemic sclerosis Nat. Rev. Rheumatol. 10 2014 706 719
-
(2014)
Nat. Rev. Rheumatol.
, vol.10
, pp. 706-719
-
-
Lafyatis, R.1
-
28
-
-
66249125359
-
A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension
-
M. Shintani, H. Yagi, T. Nakayama, T. Saji, and R. Matsuoka A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension J. Med. Genet. 46 2009 331 337
-
(2009)
J. Med. Genet.
, vol.46
, pp. 331-337
-
-
Shintani, M.1
Yagi, H.2
Nakayama, T.3
Saji, T.4
Matsuoka, R.5
-
29
-
-
84903590362
-
MicroRNA-190 regulates hypoxic pulmonary vasoconstriction by targeting a voltage-gated K(+) channel in arterial smooth muscle cells
-
S.S. Li, Y.J. Ran, D.D. Zhang, S.Z. Li, and D. Zhu MicroRNA-190 regulates hypoxic pulmonary vasoconstriction by targeting a voltage-gated K(+) channel in arterial smooth muscle cells J. Cell Biochem. 115 2014 1196 1205
-
(2014)
J. Cell Biochem.
, vol.115
, pp. 1196-1205
-
-
Li, S.S.1
Ran, Y.J.2
Zhang, D.D.3
Li, S.Z.4
Zhu, D.5
|