Does the preclinical evidence for functional remyelination following myelinating cell engraftment into the injured spinal cord support progression to clinical trials?

Experimental Neurology

Volumn 283, Issue , 2016, Pages 560-572

  Myers, Scott A ^a   Bankston, Andrew N ^a   Burke, Darlene A ^a   Ohri, Sujata Saraswat ^a   Whittemore, Scott R ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Neural precursor cells; Neural stem progenitor cells; Oligodendrocytes; Remyelination; Schwann cells; Spinal cord injury; Transplantation

Indexed keywords

GROWTH FACTOR; MYELIN;

CENTRAL NERVOUS SYSTEM; CLINICAL TRIAL (TOPIC); DISEASE COURSE; EMBRYONIC STEM CELL; ENGRAFTMENT; HUMAN; INDUCED PLURIPOTENT STEM CELL; LYMPHOID PROGENITOR CELL; NERVE CELL DIFFERENTIATION; NEURAL RESTRICTED PRECURSOR CELL; NEURAL STEM CELL; NEURAL STEM CELL TRANSPLANTATION; NEURAL STEM PROGENITOR CELL; NONHUMAN; OLIGODENDROCYTE PROGENITOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; REMYELINIZATION; REVIEW; SCHWANN CELL; SPINAL CORD INJURY; ANIMAL; DISEASE MODEL; MYELIN SHEATH; PHYSIOLOGY; SPINAL CORD INJURIES; TRANSPLANTATION;

ANIMALS; CLINICAL TRIALS AS TOPIC; DISEASE MODELS, ANIMAL; HUMANS; MYELIN SHEATH; SPINAL CORD INJURIES;

EID: 84964917722     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2016.04.009     Document Type: Review

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