The HSP70 co-chaperone DNAJC14 targets misfolded pendrin for unconventional protein secretion

Nature Communications

Volumn 7, Issue , 2016, Pages

  Jung, Jinsei ^a   Kim, Jiyoon ^a   Roh, Shin Hye ^a   Jun, Ikhyun ^a   Sampson, Robert D ^a   Gee, Heon Yung ^a,b   Choi, Jae Young ^a   Lee, Min Goo ^a  

^a Yonsei University College of Medicine   (South Korea)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEINS AND BINDING PROTEINS; HEAT SHOCK COGNATE PROTEIN 70; HSP70 COCHAPERONE DNAJC14; MUTANT PROTEIN; PENDRIN; SMALL INTERFERING RNA; SYNTAXIN; SYNTAXIN 5; UNCLASSIFIED DRUG; CARRIER PROTEIN; CHAPERONE; DNAJC14 PROTEIN, HUMAN; FETOPROTEIN; HEAT SHOCK PROTEIN 70; SLC26A4 PROTEIN, HUMAN;

AQUEDUCT; CELLS AND CELL COMPONENTS; DNA; GENE EXPRESSION; HEARING; MOLECULAR ANALYSIS; MUTATION; PROTEIN; PROTEOMICS; SECRETION; STRESS; TRAFFICKING;

ANION EXCHANGE; ARTICLE; BIOTINYLATION; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME SPECIFICITY; EXOCYTOSIS; GENETIC TRANSFECTION; GOLGI COMPLEX; HEK293 CELL LINE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LIQUID CHROMATOGRAPHY; PENDRED SYNDROME; PROTEIN FOLDING; PROTEIN SECRETION; PROTEIN TRANSPORT; PROTEOMICS; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; TRANSPORT VESICLE; UPREGULATION; CHEMISTRY; GENETICS; METABOLISM; MUTATION; NODULAR GOITER; PERCEPTION DEAFNESS;

FETAL PROTEINS; GOITER, NODULAR; GOLGI APPARATUS; HEARING LOSS, SENSORINEURAL; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR CHAPERONES; MUTATION; PROTEIN FOLDING; PROTEIN TRANSPORT;

EID: 84964810088     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms11386     Document Type: Article

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